Clinical trials: Contraceptive Device; Intrauterine
Contraception
Evaluation of ContraMed VeraCept Intrauterine Copper Contraceptive for Long Acting Reversible Contraception
Prospective, multi-center, single-arm, open-label, Phase II clinical study to evaluate the effectiveness, device placement, safety, and tolerability of VeraCept to support commencing a Phase III Clinical Study
- Trial name
- NCT02446821
- Testing
- VeraCept
- Where
- 12 sites in United States
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- Sebela Women's Health Inc.
Prevention of Pregnancy
Comparative Study of the VeraCept Low-Dose Intrauterine Copper Contraceptive vs. the TCu380 Copper IUD
The purpose of this study is to evaluate the safety and effectiveness of the VeraCept Low Dose Intrauterine Copper Contraceptive compared to the standard T shaped copper IUD, the TCu380.
- Trial name
- NCT02167763
- Testing
- VeraCept Intrauterine Copper Contraceptive, TCu380 IUD
- Where
- Dominican Republic
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sebela Women's Health Inc.
Postpartum Contraception, Reproductive Health
Predictors of PPIUCD Discontinuation at Two Years: A Clinical Study in Pakistan
This prospective cohort study evaluated the continuation rates, complications, and satisfaction associated with postpartum intrauterine contraceptive devices (PPIUCDs) as a long-acting reversible contraception (LARC) method.
- Conditions
- Postpartum Contraception, Reproductive Health, Family Planning
- Trial name
- NCT06766396
- Testing
- Postpartum Intrauterine Contraceptive Device (PPIUCD).
- Where
- Pakistan
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Uterine Hemorrhage
Management of Initial Bleeding/Spotting Associated With the Levonorgestrel-releasing Intrauterine System (MIRENA)
The purpose of the study is to investigate if the study drugs (tranexamic acid or mefenamic acid) can control irregular bleeding during the first 3 months of using Mirena.
- Trial name
- NCT01295294
- Testing
- Tranexamic acid, Mefenamic acid, Mirena (Levonorgestrel IUS, BAY86-5028)
- Where
- 12 sites in Denmark, Ireland and 1 more
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Bayer
Menorrhagia
Treatment of Copper Intra Uterine Device Associated Heavy Menstrual Blood Loss
Intrauterine contraceptive device is the most commonly reversible method used among women of reproductive age worldwide. Almost one in five married contraceptive users is currently using Intrauterine contraceptive device.
- Trial name
- NCT03139422
- Testing
- Tranexamic Acid 500 MG, Calcium Dobesilate
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Assiut University
Contraception
Postplacental Intrauterine Device Insertion: A Mixed Methods Assessment of Women's Experience
The primary objective of this mixed methods pilot study is to understand women's experiences with postplacental intrauterine device (IUD) insertion through postpartum semi-structured interviews.
- Trial name
- PIPPI (NCT02312726)
- Testing
- Postplacental IUD insertion
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Contraception
Evaluation of a Novel and Simplified Technique for Intrauterine Contraceptive Devices Insertion: a Prospective Cohort Study
The intrauterine devices (IUDs) are a safe, reliable, long-acting and reversible contraceptive method. It is also sound safe and cheap contraceptive methods available and is nearly maintenance free for up to 10 years.
- Trial name
- NCT02841826
- Testing
- IUD, Uterine sounding, Transvaginal ultrasound
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Contraception
Online Peer Influence on IUD Behaviors and Attitudes
This study will look at women's social communication about IUDs (intrauterine devices) and their attitudes and behavior related to IUD use.
- Trial name
- NCT02279043
- Testing
- Interaction with users of IUC and non-IUC users, Interaction with non-IUC users only
- Where
- United States
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Intrauterine Contraceptive Device Complication
A Comparative Study Evaluating Pain Experienced During Intrauterine Device Insertion in Women
The intrauterine device (IUD) is a reversible contraceptive method with good efficacy and long-lasting action. One of the obstacles to IUD insertion, both for healthcare professionals and patients, is the fear of painful…
- Trial name
- DODIU (NCT07437235)
- Where
- France
- Volunteers
- 162 people
- Sponsor
- University Hospital, Rouen
Contraception
KYleena Satisfaction Study / Observational Study on User Satisfaction With the Levonorgestrel Intrauterine Delivery System Kyleena (LNG-IUS 12) in New Contraceptive Users and After Switching From Another Contraceptive Method
The main goal of this non-interventional study (NIS) is to evaluate user satisfaction with Kyleena in a real-life setting and to identify factors which influence user satisfaction, taking into account previously used…
- Trial name
- KYSS (NCT03182140)
- Testing
- Kyleena
- Where
- 19 sites in United States, Belgium and 6 more
- Volunteers
- 1,134 people, healthy volunteers welcome
- Sponsor
- Bayer
Contraception
Pharmacodynamics and Pharmacokinetics Study of Existing DMPA Contraceptive Methods
This is a randomized, multi-center, parallel-group Phase I study to evaluate the pharmacodynamics (PD) of Medroxyprogesterone Acetate (MPA) after a single subcutaneous (SC) injection of 150 mg/mL or 300 mg/2 mL Depo-Provera CI in…
- Trial name
- NCT02456584
- Testing
- DMPA 150, DMPA 300, DMPA 104
- Where
- 2 sites in United States, Dominican Republic
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- FHI 360
HIV, Contraception
Impact of Different Contraceptives on the Immune System of HIV Infected Women in Zambia
In this study, 66 HIV-infected women who desire contraception will be randomly assigned to use either an IUD or Depo Provera, and will be followed for six months.
- Conditions
- HIV, Contraception, HIV Infections
- Trial name
- MSRC (NCT00807625)
- Testing
- Depo Provera, Copper T Intrauterine contraception device
- Where
- Zambia
- Volunteers
- 66 people
- Sponsor
- University of Alabama at Birmingham
IUD (Intrauterine Device) Malposition, IUD; Complications, Infection or Inflammation
Clinical Outcomes of Post-placental Insertion of Cupper T380A and Multiload 375 Contraceptive Devices During Cesarean Section
Clinical outcomes of post-placental insertion of Cupper T380A and Multiload 375 contraceptive devices during cesarean section
- Trial name
- NCT05624411
- Testing
- CU T380A IUD, multiload 375 IUD
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Sohag University
Intrauterine Contraceptive Device Complication
Uterine Artery Doppler and Menstrual Changes After Insertion Intrauterine Contraceptive Device
To evaluate the correlation between uterine artery Doppler indices and subsequent menstrual changes after 3 months of insertion of copper T-380 IUD and LNG-IUS
- Trial name
- NCT05986344
- Testing
- Copper intrauterine contraceptive device, LNG-IUS
- Where
- Egypt
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Contraception
LCS12 vs Combined Oral Contraceptive (COC) User Satisfaction Study
The primary objective of this study is to evaluate user satisfaction and tolerability in young women (18-29 years of age) using the LCS12 compared with young women using a COC (Yasmin) over a period of 18 months.
- Trial name
- NCT01254292
- Testing
- Levonorgestrel IUD (LCS, BAY86-5028), Yasmin (EE30/DRSP, BAY86-5131)
- Where
- 94 sites in United States, Austria and 3 more
- Volunteers
- 567 people
- Sponsor
- Bayer
Reproductive Health
RH and Adolescents
This study will create a model of reproductive health services for HIV-positive female adolescents in Asia.
- Trial name
- NCT02713750
- Testing
- reversible contraceptive methods
- Where
- 4 sites in Thailand
- Volunteers
- 77 people
- Sponsor
- The HIV Netherlands Australia Thailand Research Collaboration
Attitudes
Pilot #2 of Social Network Intrauterine Contraceptive (IUC) Intervention
This study has two goals: 1) to test an approach to helping women who use intrauterine contraception (IUC) spread the word about this type of long-lasting, highly effective birth control method among their friends and family and…
- Trial name
- NCT02242890
- Testing
- Contraception Information Packet
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Contraception Desired, Obesity
Levonorgestrel-releasing Intrauterine Device on Obese Women: Effects on Hemostatic and Arterial Function
Obesity is a disorder associated with metabolic dysfunction and changes in cardiovascular risk markers; the use of oral contraceptives (OCs) may exert a further negative effect on these alterations in patients with PCOS.
- Trial name
- NCT01320917
- Testing
- Levonorgestrel releasing device, Cu-IUD insertion
- Where
- Brazil
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Contraception
A proof-of Concept, Randomized 3-month Study to Evaluate the Effects of Three Contraceptive Intrauterine Systems Delivering Copper and a Daily Dose of 5, 20 or 40 μg of Ulipristal Acetate (UPA)
The UPA doses to be tested in this new IUS, 5, 20 or 40 μg per day, are not expected to suppress ovulation, however they should prevent endometrial growth resulting in endometrial atrophy, minimal bleeding, or even amenorrhea.
- Trial name
- NCT03230539
- Testing
- Ulipristal Acetate IUS delivering Cu and 5μg, Ulipristal Acetate IUS delivering Cu and 20μg, Ulipristal Acetate IUS delivering Cu and 40μg
- Where
- Dominican Republic
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Population Council
Medicated Intrauterine Devices, Contraception
Mirena Efficiency and Tolerability During the First Year of Use
In this trial the efficacy and safety of Mirena was investigated during the first year of use
- Trial name
- NCT00696202
- Testing
- Mirena (BAY86-5028)
- Where
- France
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Bayer