Clinical trials: Contraceptive Devices
Emergency Contraception
A Study of Use of Ella®, an Emergency Contraceptive, Under Simulated OTC Conditions
This study is designed to assess whether consumers select and use ella® (ulipristal acetate 30mg), an emergency contraceptive, in a manner consistent with the OTC package directions in an OTC-like setting.
- Trial name
- LIBRella (NCT03208985)
- Testing
- Use Phase (Ulipristal Acetate, 30 mg)
- Where
- 34 sites in United States
- Volunteers
- 1,270 people, healthy volunteers welcome
- Sponsor
- HRA Pharma
Contraceptive Usage, Diffuse Noxious Inhibitory Control
Effects of Oral Contraceptives on DNIC in Non-painful Healthy Women
The purpose of this study is tu assess the influence of oral contraceptives (OC) on diffuse noxious inhibitory control (DNIC) in healthy women, tested during high, low endogenous estrogens sessions and ovulatory period.
- Trial name
- NCT04365426
- Testing
- Mechanical stimulus, Thermal (cold) stimulus, Oral contraceptive (OC)
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Vina del Mar
Abortion
Impact of Video Intervention on Postabortal Uptake of Long Acting Reversible Contraception (LARC)
Primary: To compare rates of immediate postabortal LARC uptake between women exposed to a brief, theory-based, video intervention prior to standard contraceptive counseling and women exposed to standard counseling alone.
- Trial name
- LARC IUD (NCT01945385)
- Testing
- Video intervention
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Contraception
Study to Investigate Efficacy and Safety of a New Oral Contraceptive
The purpose of this study is to evaluate the safety and effectiveness of a new 4-phasic preparation in the prevention of pregnancies in a large group of volunteers.
- Trial name
- NCT00185289
- Testing
- EV/DNG (Qlaira, BAY86-5027, SH T00658K)
- Where
- 50 sites in Austria, Germany and 1 more
- Volunteers
- 1,392 people, healthy volunteers welcome
- Sponsor
- Bayer
Contraception, Female Contraception
A Study to Evaluate the Hormone Exposure From Multiple Commercial Lots of ORTHO EVRA (a Transdermal Contraceptive Patch)
The objective of this study is to estimate the exposure to the hormones norelgestromin, norgestrel, and ethinyl estradiol in the bloodstream of healthy female volunteers across multiple commercial lots of ORTHO EVRA® (a…
- Trial name
- NCT00258076
- Testing
- EVRA transdermal contraceptive patch 6 mg NGMN and 0.75 mg EE
- Volunteers
- 53 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Contraception
An Exploratory Study of ZB-06 as a Vaginal Contraceptive Film
This is an early Phase 1 study to establish proof-of-concept by determining whether an intravaginal film containing a human contraceptive antibody (ZB-06) shows promise to provide contraceptive efficacy using the post-coital…
- Trial name
- NCT04731818
- Testing
- ZB-06
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- KBio Inc
Endometrioma
Effect of Elagolix in Symptomatic Endometrioma in Comparison to Combined Oral Contraceptive Pill.
women of 18-40 years with symptomatic endometrioma (moderate to severe dysmenorrhea with endometrioma(2-5cm),will be allocated into 2 groups-Experimental group (group A) and comparatorgroup( group B).Experimental…
- Trial name
- endometrioma (NCT07763847)
- Testing
- tab Elagolix 150mg, Combined oral contraceptive pill (ethinyl estradiol,30mcg+desogestrel,150mcg) tablet
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- Mst.Sumyara Khatun
Bone; Disorder, Development and Growth
Effects of Oral vs. Non-oral Contraceptives on the GH/IGF-1 Axis
This study will determine whether the negative effects of combined oral contraceptive (COC) therapy on the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis and bone turnover are dependent on the route of administration…
- Trial name
- NCT02367833
- Testing
- Combined Oral Contraceptive, Transdermal Contraceptive, Contraceptive Vaginal Ring
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Penn State University
Hiv, Contraception Behavior
TwySHE - An Mhealth Peer-navigator Intervention to Increase PrEP and Contraceptive Use
The goal of this clinical trial is to learn if the TwySHE intervention can increase the use of HIV prevention in at-risk female university students aged 18-24 in Zambia.
- Trial name
- NCT06852508
- Testing
- TwySHE
- Where
- Zambia
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Contraceptive Usage
Injectable Contraception Cohort Study in Punjab, Pakistan
The aim of this study is to assess the value proposition of expanding contraceptive options available to women in Punjab, Pakistan to include subcutaneous depot medroxyprogesterone acetate (DMPA-SC). Specific objectives are: 1.
- Trial name
- NCT05774626
- Testing
- Contraceptive usage
- Where
- 41 sites in Pakistan
- Volunteers
- 1,009 people, healthy volunteers welcome
- Sponsor
- Jhpiego
Healthy Adult Premenopausal Female Volunteers
Study of the Effect of ITCA 650 on the PK/PD of Oral Contraceptive in Healthy Female Subjects
A Phase 1, randomized, double-blind, placebo-controlled, crossover study to assess the effect of ITCA 650 on the pharmacokinetics (PK) of once daily administration of Levora® (ethinyl estradiol 0.3 mg (EE) and levonorgestrel 0.15…
- Trial name
- NCT02641990
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Intarcia Therapeutics
Vaginal Infection
Relation Between Internal Vaginal Douching and Vaginal Infections in Intrauterine Contraceptive Device Users
To determine the effect of performing internal vaginal douching on the frequency and severity and type of vaginal infections in IUD users
- Trial name
- NCT03261804
- Testing
- relation between vaginal douching and vaginal infection
- Where
- Egypt
- Volunteers
- 604 people
- Sponsor
- Assiut University
Female Contraception
Study to Evaluate Contraceptive Efficacy and Safety of a Progestin Only Patch in Women of Childbearing Potential
The Sponsor is developing a progestin-only contraceptive transdermal system (patch). The main purpose of this study is to look at how safe the study patch is and how well it works in preventing pregnancy.
- Trial name
- NCT06672016
- Testing
- Transdermal system containing progestin
- Where
- 56 sites in United States
- Volunteers
- 1,630 people
- Sponsor
- Mylan Pharmaceuticals Inc
Hepatitis C Virus
A Study in Healthy Female Participants Investigating the Effect of TMC435 on the Pharmacokinetics of the Synthetic Hormones of the Oral Contraceptive Ovysmen
The purpose of this study is to investigate the effect of steady-state concentrations of TMC435 (administered once a day) on the steady-state pharmacokinetics of ethinylestradiol and norethindrone (administered once a day) and on…
- Trial name
- NCT01486004
- Testing
- TMC435, Ovysmen
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Tibotec Pharmaceuticals, Ireland
Contraception
Pharmacodynamics and Pharmacokinetics Study of Existing DMPA Contraceptive Methods
This is a randomized, multi-center, parallel-group Phase I study to evaluate the pharmacodynamics (PD) of Medroxyprogesterone Acetate (MPA) after a single subcutaneous (SC) injection of 150 mg/mL or 300 mg/2 mL Depo-Provera CI in…
- Trial name
- NCT02456584
- Testing
- DMPA 150, DMPA 300, DMPA 104
- Where
- 2 sites in United States, Dominican Republic
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- FHI 360
Endometriosis Ovary
Comparing the Safety and Efficacy in the Use of Hormonal Therapy on Endometriosis Patients After Conservative Surgery
The goal of this clinical trial is to compare safety and efficacy in endometriosis patient after conservative surgery. The main question[s] it aims to answer are: 1. Health-related quality of life (HRQoL) 2. VAS score 3.
- Trial name
- ENDOSafe (NCT06145438)
- Testing
- Dienogest, Depo Medroxyprogesterone acetate, Leuprolide (as Leuprolide Acetate)
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- Universitas Diponegoro
Abortion
Trial of Immediate Versus Delayed Initiation of Oral Contraceptive Pills After Abortion
This is a randomized, controlled trial investigating whether immediate versus standard, "Sunday Start", initiation of oral contraceptive pills (OCPs) in post-abortion subjects can improve compliance and the continuation of…
- Trial name
- NCT00235534
- Testing
- Immediate initiation of OCPs, Delayed initiation of OCPs
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Healthy
Study Comparing Two Manufacturing Processes for Levonorgestrel 90 mg/Ethinyl Estradiol 20 mg (LNG/EE) in Healthy, Cycling Women
Primary Objective: To determine the bioequivalence between the clinical batch process and the new processes for manufacturing LNG/EE.
- Trial name
- NCT00319163
- Testing
- levonorgestrel/ethinyl estradiol
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Contraception
Study of Safety and Efficacy of an Oral Contraceptive
This is a non-comparative study. the primary objective of the study is to assess the efficacy of a low dose oral contraceptive in the prevention of pregnancy.
- Trial name
- NCT00477633
- Testing
- Norethindrone/ethinyl estradiol
- Where
- 63 sites in United States
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- Warner Chilcott
Contraception
US Cycle Control and Blood Pressure Study
Birth Control Patch Study
- Trial name
- NCT00920985
- Testing
- Gestodene/EE (FC Patch Low, BAY86-5016), Oral contraceptive (equivalent to the active treatment tablets of Levlite), 21-day blister SH D00593A
- Where
- 28 sites in United States
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- Bayer