Clinical trials: Contraceptive Devices
Endometriotic Cyst of Ovary
Letrozole in Preventing Recurrence of Endometrioma Following Laparoscopic Ovarian Cystectomy
Endometriosis is a chronic inflammatory disease that affects approximately 10-15% of women of reproductive age. Symptoms include dysmenorrhoea, chronic pelvic pain, dyspareunia and infertility.
- Trial name
- NCT05487092
- Testing
- Letrozole
- Where
- 5 sites in Hong Kong
- Volunteers
- 194 people
- Sponsor
- The University of Hong Kong
Healthy
A Study To Estimate The Effect of PF-06650833 On The Pharmacokinetics (PK) of Oral Contraceptive (OC)
This is a Phase 1, open label, fixed sequence study of the effect of multiple dose PF-06650833 on single dose OC PK in healthy female subjects.
- Trial name
- NCT05064332
- Testing
- PF-06650833, Ethinyl estradiol (EE) and levonogestrel (LN)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pfizer
Contraceptive Use After Emergency Contraception
Initiating Contraception After Emergency Contraception From Pharmacy
Pharmacists do not provide immediate contraception to women after emergency contraception (EC); they can only give advice on local contraceptive services.
- Trial name
- NCT01738971
- Testing
- rapid access, one month progestogen only pill
- Where
- United Kingdom
- Volunteers
- 168 people
- Sponsor
- University of Edinburgh
Healthy
Validation of Reproductive Autonomy and Contraceptive Autonomy Scales Among Egyptian Women
This study aims to: 1. To validate Arabic version of the reproductive autonomy scale among married women in reproductive age group (15-49 year) in Assiut. 2.
- Trial name
- NCT04803526
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Assiut University
Contraceptive Usage
Expanded Program for Immunization, a Missed Opportunity for Postpartum Family Planning Utilization
This study is aimed to enhance postpartum family planning by integrating family planning information with infant immunization services, which is the most widely utilized health services globally.
- Trial name
- NCT04780243
- Testing
- counseling
- Where
- Ethiopia
- Volunteers
- 1,474 people, healthy volunteers welcome
- Sponsor
- Hawassa University
Bacterial Vaginosis, HIV
Effects of Contraceptive Ring on Vaginal Microbiota, HIV Shedding and Local Immunity
The investigators propose to explore the hypothesis-supported by limited data-that a contraceptive vaginal ring (CVR) that is commonly used in the United States, the NuvaRing, will enhance women's genital and reproductive health.
- Trial name
- NCT02445989
- Testing
- NuvaRing
- Where
- Kenya
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Washington
Ovulation Inhibition
A Study to Evaluate the Effect of a Contraceptive Vaginal Ring Delivering Ulipristal Acetate Combined With a Single or Repeated Levonorgestrel on Inhibition of Ovulation, Endometrial Changes and Bleeding Patterns in Normal Cycling Women
The purpose of this study is to determine the effect of a contraceptive vaginal ring on inhibition of ovulation, endometrial changes and bleeding patterns in normal cycling women.
- Trial name
- NCT02451826
- Testing
- Ulipristal acetate
- Where
- Dominican Republic
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Population Council
Contraception Behavior, Contraception
The Influence of Trust in the Health Care System on Postpartum Contraceptive Choice
The purpose of this research is to understand the relationship between trust in the health care system and choice of contraception during the postpartum period among pregnant women receiving prenatal care.
- Trial name
- NCT02213874
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Contraception, Obesity
The Effect of Body Mass Index on Etonogestrel Hormone Levels in Women Using the Single-rod Contraceptive Implant
Two-thirds of young women in the United States are overweight or obese. This excess weight may affect how their body metabolizes drugs such as different birth control methods.
- Trial name
- Eto BMI (NCT01855620)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Columbia University
Contraceptive Usage, Telemedicine
Telemedicine Contraceptive Counselling (TECC) Versus Standard Care
Overall purpose of the PILOT and RCT: This research project aims to increase access and uptake of contraception after abortion through the systematic development and testing of a new telemedicine service for contraceptive…
- Trial name
- TECC (NCT06682065)
- Testing
- Telemedicine for contraceptive counseling (TECC), Standard Care
- Where
- 2 sites in South Africa
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Contraception, Female Contraception
A Study of Efficacy and Safety With the Transdermal Contraceptive System.
The purpose of the study is to evaluate the contraceptive efficacy, safety, cycle control, and compliance with the transdermal contraceptive system.
- Trial name
- NCT00236769
- Testing
- norelgestromin + ethinyl estradiol
- Volunteers
- 1,751 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Contraception Behavior
Debunking Myths About Contraceptive Safety Among Women in Kingston, Jamaica
The primary hypothesis is that the intervention video - based on strategies from cognitive psychology - can correct women's misinformation about long-acting reversible contraception (LARC) and result in higher use of LARC.
- Trial name
- NCT03775642
- Testing
- Intervention video, Control video
- Where
- Jamaica
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Substance Use Disorder (SUD), Sexual and Reproductive Health
WORTH Paths Intervention
Women in the criminal legal system are more likely to experience substance use disorders and unintended pregnancy than women in the general public.
- Conditions
- Substance Use Disorder (SUD), Sexual and Reproductive Health, Sexual Risk Behavior
- Trial name
- NCT06889831
- Testing
- WORTH Paths Digital Intervention, WORTH Paths Wellness Group
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Fairleigh Dickinson University
Polycystic Ovary Syndrome (PCOS), Overweight
The Effect of GLP-1 Agonists Versus OCs on Reproductive Disorders and Cardiovascular Risks in Overweight PCOS
Polycystic ovary syndrome (PCOS) is a health problem that affects one in 10 women of childbearing age, which is usually characterized by hormonal imbalance and metabolism problems such as hyperandrogenism and obesity.
- Conditions
- Polycystic Ovary Syndrome (PCOS), Overweight, Obesity
- Trial name
- NCT03151005
- Testing
- Metformin-GLP-1 Receptor Agonist, Metformin-Oral Contraceptive(OC)
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Xinqiao Hospital of Chongqing
Postpartum Depressive Mood, Postpartum Sexual Function
Oral Contraceptive Ethinyl Estradiol Dose Effect on Postpartum Depression and Sexual Functioning Scales
This is a prospective, randomized, controlled cohort study. This study will look at the effect of Ethinyl Estradiol 35mcg/Norethindrone 1mg and Ethinyl Estradiol 20 mcg/Norethindrone 1mg on postpartum depressive symptoms and…
- Trial name
- NCT02210702
- Testing
- Ethinyl Estradiol 35mcg/Norethindrone 1mg, Ethinyl Estradiol 20mcg/Norethindrone 1mg
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- The Jones Institute
Dysmenorrhea
A Study to Evaluate the Effect of Contraceptive Vaginal Rings on Primary Dysmenorrhea (P08257/MK-8175A/MK-8342B-057)
The study investigates four vaginal ring groups with respect to relief of primary dysmenorrhea, and should identify at least one vaginal ring that shows clinically relevant treatment efficacy in relief of primary dysmenorrhea.
- Trial name
- NCT01670656
- Testing
- Nomegestrol acetate contraceptive vaginal ring (NOMAC-CVR), Etonogestrel containing contraceptive vaginal ring (ENG-CVR), Ibuprofen
- Volunteers
- 439 people
- Sponsor
- Organon and Co
Uterine Hemorrhage
Management of Initial Bleeding/Spotting Associated With the Levonorgestrel-releasing Intrauterine System (MIRENA)
The purpose of the study is to investigate if the study drugs (tranexamic acid or mefenamic acid) can control irregular bleeding during the first 3 months of using Mirena.
- Trial name
- NCT01295294
- Testing
- Tranexamic acid, Mefenamic acid, Mirena (Levonorgestrel IUS, BAY86-5028)
- Where
- 12 sites in Denmark, Ireland and 1 more
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Bayer
Contraceptive Usage
Contraception Decision Aid Use and Patient Outcomes
The purpose of this study is to assess the impact of a contraception decision aid mobile application on: (a) decisional conflict, (b) reproductive health self-efficacy, (c) contraceptive and reproductive health literacy, and (d)…
- Trial name
- NCT05177783
- Testing
- Tuune health questionnaire, Control health questionnaire
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Texas Christian University
Hormonal Contraception
Contraceptive Hormones, Immunity, and Microbiome Evaluation
The study is a prospective cohort study to explore the mechanisms underlying the HIV risk associated with pharmacologic doses of exogenous sex hormones via hormonal contraceptives specially progestin-containing hormonal…
- Trial name
- CHIME (NCT03660046)
- Testing
- Depot medroxyprogesterone acetate (DMPA), Etonogestrel implant (Eng-Implant), Levonorgestrel IUD (Lng-IUD)
- Where
- 3 sites in United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Emory University
Pregnancy
Study of the Safety and Contraceptive Efficacy of C31G Compared to Conceptrol®
This is a multicenter, randomized, double-masked, controlled, phase III study of repeated use of C31G vaginal gel compared to Conceptrol® Vaginal Gel as the primary method of contraception over six months (183 days) and at least…
- Trial name
- NCT00274261
- Testing
- C31G, nonoxynol-9 (N-9)
- Where
- 15 sites in United States
- Volunteers
- 1,565 people, healthy volunteers welcome
- Sponsor
- Premier Research