Clinical trials: Contraceptive Devices
Contraception
Study of Safety and Efficacy of an Oral Contraceptive
This is a non-comparative study. the primary objective of the study is to assess the efficacy of a low dose oral contraceptive in the prevention of pregnancy.
- Trial name
- NCT00477633
- Testing
- Norethindrone/ethinyl estradiol
- Where
- 63 sites in United States
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- Warner Chilcott
Healthy Volunteers
Drug-drug Interaction Study of CTP-543 and Oral Contraceptives in Healthy Female Subjects
This is a Phase 1, fixed sequence, multiple dose, open-label study of the effect of CTP-543 on oral contraceptive pharmacokinetics in healthy female subjects.
- Trial name
- NCT04309643
- Testing
- CTP-543, Combined oral contraceptive containing Ethinyl estradiol (EE) and Levonorgestrel (LNG)
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Concert Pharmaceuticals
Ligament Injury
Do Oral Contraceptives Protect Against ACL Injuries in Female Athletes
The purpose of this research study is to examine the impact of one type of commonly used birth control pill on blood levels of relaxin and measure changes in knee movement to determine whether there are changes in joint…
- Trial name
- OC (NCT04899778)
- Testing
- Oral Contraceptive Pill, norethindrn a-e estradiol-iron
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Contraception
Effects of Hormonal Contraceptives on Liver Proteins and Coagulation Factors: A Comparison of a Contraceptive Vaginal Ring and an Oral Contraceptive
The purpose of this 3-month (cycle) study was to evaluate the effects of hormonal contraceptives containing a progestin and an estrogen on liver proteins and coagulation factors that are sensitive to estrogen.
- Trial name
- NCT00213096
- Testing
- Nestorone/ethinyl estradiol contraceptive vaginal ring; levonorgestrel/ethinyl estradiol oral contraceptive
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Population Council
Opioid-use Disorder, Contraception
Averting NAS Among Opioid-Using Young Women Receiving MAT Using Buprenorphine
The primary objective of this study is to test the efficacy of a Motivational Interviewing and Educational Training intervention with immediate linkage to long acting reversible contraception (LARC) (hereafter known as MIET).
- Conditions
- Opioid-use Disorder, Contraception, Neonatal Abstinence Syndrome
- Trial name
- NAS-MIET (NCT04611659)
- Testing
- Motivational Interviewing and Educational Training (MIET)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Meharry Medical College
Contraception Behavior, Contraceptive Usage
Contraceptive Equity Study 2016
The purpose of this study is to assess the impact of a provider counseling training on patient contraceptive behaviors and satisfaction in a clustered randomized trial among 10 Planned Parenthood health centers.
- Conditions
- Contraception Behavior, Contraceptive Usage, Contraceptive Method Switching
- Trial name
- CES (NCT03012659)
- Testing
- Contraceptive Counseling Training
- Where
- United States
- Volunteers
- 1,015 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood Federation of America
Contraception
Endometrial Biopsy in Progestin Contraceptive Users
The purpose of the study is to learn more about menstrual changes in progestin contraception users. The investigators are hoping to find out what changes in the endometrium lead to different bleeding patterns during the first…
- Trial name
- NCT05760144
- Testing
- DMPA, Etonogestrel implant
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Copper Intrauterine Device Induced Bleeding
Study About Patients Using Copper Intrauterine Device
THE AIM OF THE this study is to assess the hemodynamic changes of uterine artery in patients with CIUD induced bleeding by using transvaginal color Doppler indices (uterine artery resistance index and pulsatility index) to prove…
- Trial name
- IUD (NCT01541241)
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Egymedicalpedia
Rheumatoid Arthritis
The Effect of BMS-986195 Combined With an Oral Contraceptive (Ethinyl Estradiol/Norethindrone) in Healthy Female Patients
The purpose of this study is to investigate the effect of BMS-986195 in combination with an oral contraceptive in healthy female patients.
- Trial name
- NCT03262740
- Testing
- BMS-986195, Loestrin 1.5/30 (1.5 mg norethindrone acetate/30 μg ethinyl estradiol)
- Where
- 2 sites in United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Contraception
A Study to Assess Contraceptive Efficacy and Safety of Etonogestrel (ENG) Implant Beyond 3 Years of Use (MK-8415-060)
The primary purpose of this study is to assess the efficacy and safety of the etonogestrel (ENG) contraceptive implant during participants' fourth and fifth years of use when used as the only method of contraception.
- Trial name
- NCT04626596
- Testing
- Radiopaque Etonogestrel (ENG) Implant
- Where
- 67 sites in United States, Puerto Rico
- Volunteers
- 498 people
- Sponsor
- Organon and Co
Oral Contraceptive
Study Evaluating Levonorgestrel and Ethinyl Estradiol for Oral Contraception
The purpose of this study is to evaluate the contraceptive efficacy and safety of an oral contraceptive containing a combination of LNG 100mcg/EE 20mcg compared to LNG 150mcg/EE 30 mcg.
- Trial name
- NCT02021097
- Testing
- Levonorgestrel 100 mcg and Ethinyl Estradiol 20 mcg, Levonorgestrel 150 mcg and Ethinyl Estradiol 30 mcg
- Where
- 21 sites in China
- Volunteers
- 1,008 people, healthy volunteers welcome
- Sponsor
- Regenex Pharmaceutical, China
Pregnancy Prevention
Continuous Use of COCs
The primary objective is to determine if continuous COC use leads to higher continuation rates over 12 months of follow up than use of the standard 28-day COC regimen.
- Trial name
- NCT00570440
- Testing
- Oral contraceptives--ethinyl estradiol, levonorgestrel
- Where
- 2 sites in Dominican Republic, Nicaragua
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- FHI 360
Metrorrhagia
Study of a 4-phasic Oral Contraceptive for the Treatment of Heavy Menstrual Bleeding
To evaluate efficacy and safety of a combined oral contraceptive of estradiol valerate and dienogest in the treatment of heavy menstrual bleeding
- Trial name
- NCT01638923
- Testing
- EV/DNG (Qlaira, Natazia, BAY86-5027)
- Where
- 41 sites in China, Philippines and 4 more
- Volunteers
- 339 people
- Sponsor
- Bayer
Contraception
Contraceptive Efficacy, Tolerance and Acceptability of a Benzalkonium Chloride Spermicide Cream In Women Aged Over 40 Years of Age
In spite of many advantages of spermicides, there is no contraceptive efficacy study conducted with any spermicide in women aged over 40 years.
- Trial name
- BZK40+ (NCT03102450)
- Testing
- Benzalkonium Chloride Spermicide Cream
- Where
- 15 sites in France, Russia
- Volunteers
- 151 people
- Sponsor
- Laboratoire Innotech International
Contraception
A Multicenter, Non-Comparative Trial on the Contraceptive Efficacy, Safety, and Tolerability of LPRI-424, 13 Cycles
The main objective of this trial is to demonstrate the contraceptive efficacy of LPRI424, Additional goals of the trial are to demonstrate the safety and tolerability of LPRI424.
- Trial name
- NCT03945513
- Testing
- LPRI424 (dienogest/ethinylestradiol)
- Where
- United States
- Volunteers
- 1,034 people, healthy volunteers welcome
- Sponsor
- Insud Pharma
Cushing's Syndrome
A Study of the Efficacy and Safety of CORLUX in the Treatment of Endogenous Cushing's Syndrome
Patients will receive Corlux (mifepristone) daily for up to 24 weeks. Assessments of the signs and symptoms of Cushing's syndrome will be obtained.
- Trial name
- SEISMIC (NCT00569582)
- Testing
- mifepristone
- Where
- 17 sites in United States
- Volunteers
- 50 people
- Sponsor
- Corcept Therapeutics
Hepatitis C Virus
A Study in Healthy Female Participants Investigating the Effect of TMC435 on the Pharmacokinetics of the Synthetic Hormones of the Oral Contraceptive Ovysmen
The purpose of this study is to investigate the effect of steady-state concentrations of TMC435 (administered once a day) on the steady-state pharmacokinetics of ethinylestradiol and norethindrone (administered once a day) and on…
- Trial name
- NCT01486004
- Testing
- TMC435, Ovysmen
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Tibotec Pharmaceuticals, Ireland
Contraception
Pharmacist-Administered Injections for Contraception
The purpose of this study is to see if it is a feasible arrangement to have women receive their second and third birth control injection (with Depo-Provera) at a pharmacy compared with receiving it a Planned Parenthood Clinic.
- Trial name
- PAD (NCT00775047)
- Testing
- Pharmacist-administered, clinic-administered injections
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Contraceptive Usage
Injectable Contraception Cohort Study in Punjab, Pakistan
The aim of this study is to assess the value proposition of expanding contraceptive options available to women in Punjab, Pakistan to include subcutaneous depot medroxyprogesterone acetate (DMPA-SC). Specific objectives are: 1.
- Trial name
- NCT05774626
- Testing
- Contraceptive usage
- Where
- 41 sites in Pakistan
- Volunteers
- 1,009 people, healthy volunteers welcome
- Sponsor
- Jhpiego
Bipolar Disorder
Oral Contraceptive Interaction Study for GW273225
GW273225 is in development for epilepsy and bipolar disorder and can affect women of child bearing potential. A clear understanding of the potential interaction between oral contraceptives and GW273225 is therefore important for…
- Trial name
- NCT00483535
- Testing
- GW273225, COC
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline