Clinical trials: Contraceptive Devices
Drug Interaction
Pharmacokinetics and Pharmacodynamics of the Etonogestrel Contraceptive Implant When Co-administered With Efavirenz
This study evaluates whether there is an interaction between etonogestrel, the progestin hormone released by the contraceptive implant Nexplanon, and efavirenz, a common medication used to treat HIV.
- Trial name
- NCT01980342
- Testing
- Efavirenz
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Contraception, Breastfeeding
Immediate Postpartum Contraceptive Implant Placement and Breastfeeding Success in Women at Risk for Low Milk Supply: A Non-inferiority Trial
The investigators goal is to measure the impact of timing of postpartum contraceptive implant insertion on breastfeeding success and duration and to explore women's experiences with and attitudes towards contraceptive and…
- Conditions
- Contraception, Breastfeeding, Postpartum Contraception
- Trial name
- NCT02866279
- Testing
- Etonogestrel Contraceptive Implant
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Drug Interactions, Contraception
A Drug Interaction Study of Folic Acid and Oral Contraceptive Tablets Containing Norgestimate (NGM)/Ethinyl Estradiol (EE) in Healthy Women.
The purpose of the study is to assess the effect of folic acid administration on the blood level and the breakdown products of oral contraceptive (OC) [250 mcg NGM/35 mcg EE] tablets.
- Conditions
- Drug Interactions, Contraception, Pharmacokinetics
- Trial name
- NCT00709332
- Testing
- Norgestimate; Ethinyl Estradiol; Folic acid
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Intravaginal Ring Use
Women's Input on Sexual Health
The purpose of this study is to answer the following question: How do user sensory perceptions and experiences (USPEs) for IVRS differ between initial and continued use and how can this knowledge help product developers better…
- Trial name
- WISH (NCT02057419)
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Contraception, Contraceptive Usage
Assessment of Family Planning and Immunization Service Integration in Malawi
This is a mixed methods process evaluation of a programmatic intervention to integrate family planning and immunization services at health facilities and through outreach services in Dowa and Ntchisi districts of Malawi.
- Conditions
- Contraception, Contraceptive Usage, Contraception Behavior, Infant, Newborn, Diseases
- Trial name
- NCT03404284
- Testing
- Family planning and infant immunization service integration
- Volunteers
- 43 people
- Sponsor
- Jhpiego
Unprotected Sex, Contraceptive Usage
The Evaluation of Pulse: A Mobile Health App and Teen Pregnancy Prevention Program
This study used a randomized controlled design to evaluate the efficacy of a new mobile app, Pulse, in reducing the incidence of unprotected sex among young women.
- Trial name
- NCT04043130
- Testing
- Pulse
- Where
- United States
- Volunteers
- 2,317 people, healthy volunteers welcome
- Sponsor
- Child Trends
Contraception, Fetal Growth Retardation
Obesity and Oral Contraceptive Failure
Contraceptive failure is the primary cause of unintended pregnancy in the United States. With obesity rates at epidemic proportions, any association between obesity and strategies that prevent undesired pregnancies constitutes a…
- Conditions
- Contraception, Fetal Growth Retardation, Infant, Small for Gestational Age, Obesity
- Trial name
- NCT01944306
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Contraception
Vaginal Misoprostol Before Intrauterine Contraceptive Device Insertion
the current study was conducted to assess efficacy of vaginal misoprostol before IUD insertion following previous insertion failure
- Trial name
- NCT03790371
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Adenomyosis
Levonorgestrel-releasing Intrauterine System Versus a Low-dose Combined Oral Contraceptive for Management of Adenomyosis Uteri
This study aims to compare the efficacy of LNG - IUD (Levonorgestrel releasing intrauterine device) Versus Low dose COCs (combined oral contraceptive pills) on management of heavy menstrual bleeding and Dysmenorrhea caused by…
- Trial name
- LNG-IUDvsCOCs (NCT03037944)
- Testing
- Yasmin, Metraplant-E
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Ain Shams Maternity Hospital
Contraceptive Usage
Clinical Use of a Contraceptive Decision Aid and Patient Outcomes
The study at hand aims to examine whether incorporating use of a contraceptive decision aid (Tuune for Clinics) improves outcomes for patients seeking contraceptive care.
- Trial name
- NCT05973071
- Testing
- Tuune Supplemented Contraceptive Visit, Traditional Contraceptive Visit
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Texas Christian University
Migraine
A Multicenter Study to Evaluate the Efficacy of a 91-Day Extended Cycle Oral Contraceptive for Menstrually-Related Migraine Headaches
This study is being conducted to evaluate the efficacy of a 91-day extended cycle oral contraceptive compared to placebo for decreasing the frequency and severity of menstrually-related migraine headaches.
- Trial name
- NCT00781456
- Testing
- 91-day Levonorgestrel Oral Contraceptive
- Where
- 22 sites in United States
- Volunteers
- 109 people
- Sponsor
- Duramed Research
Contraception
Effect of Motivational Counseling on the Intention to Use Modern Contraceptive Methods
This study aims to evaluate the effect of motivational interviewing-based family planning counseling on attitudes and intentions toward modern contraceptive methods among women currently using traditional contraceptive methods.
- Trial name
- NCT07184229
- Testing
- motivational interviewing-based family planning counseling, standard family planning counseling.
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Adiyaman University
Infertility
Oral Microdose Lupron Versus Luteal Estradiol Trial in Poor Responder In Vitro Fertilization (IVF) Patients
Hundreds of thousands of couples in the United States experience infertility each year. When initial measures do not help, some couples require a process called ovarian stimulation and in vitro fertilization (IVF).
- Trial name
- OMLET (NCT00826839)
- Testing
- Oral contraceptive pill and microdose lupron, E2 patch/antagonist
- Where
- United States
- Sponsor
- Weill Medical College of Cornell University
Dysmenorrhea
Efficacy and Safety,Long-term Study of Low-dose Oral Contraceptive Pill to Treat Dysmenorrhea.
The purpose of this long-term study is to determine whether combination oral contraceptive pill of Norethindrone \& Ethinyl estradiol is effective in the treatmentof dysmenorrhea associated with endometriosis.
- Trial name
- NCT00212277
- Testing
- Norethindrone,Ethinyl Estradiol
- Sponsor
- Nobelpharma
Contraception, Abortion
Understanding Women's Contraceptive Expectations at the Time of a First Trimester Surgical Abortion
The investigators will conduct a voluntary anonymous survey at four separate Sacramento area family planning clinics. The investigators will ask the staff at each facility to offer a survey to all women 18 and older presenting to…
- Trial name
- NCT01807715
- Testing
- survey
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Bipolar Disorder
Oral Contraceptive Interaction Study for GW273225
GW273225 is in development for epilepsy and bipolar disorder and can affect women of child bearing potential. A clear understanding of the potential interaction between oral contraceptives and GW273225 is therefore important for…
- Trial name
- NCT00483535
- Testing
- GW273225, COC
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy
A Study to Assess the Effects of Canagliflozin (JNJ-28431754) on the Pharmacokinetics and Safety of an Oral Contraceptive in Healthy Volunteers
The purpose of this study is to investigate whether there is a drug-drug interaction between multiple doses of canagliflozin (JNJ-28431754) and single doses of an oral contraceptive containing ethinyl estradiol and…
- Trial name
- NCT01714193
- Testing
- Oral contraceptive, Canagliflozin (JNJ-28431754)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Vaginal Infection
Relation Between Internal Vaginal Douching and Vaginal Infections in Intrauterine Contraceptive Device Users
To determine the effect of performing internal vaginal douching on the frequency and severity and type of vaginal infections in IUD users
- Trial name
- NCT03261804
- Testing
- relation between vaginal douching and vaginal infection
- Where
- Egypt
- Volunteers
- 604 people
- Sponsor
- Assiut University
Contraception, Pharmacogenomic Drug Interaction
Oral Contraceptive Pill (OCP) Pharmacogenomics
The goal of this clinical trial is to evaluate how differences in specific parts of our DNA can influence how individual bodies break down the hormones contained within oral contraceptive pills, which could affect how well these…
- Trial name
- NCT06334315
- Testing
- Desogestrel / Ethinyl Estradiol Pill
- Where
- 2 sites in United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Yale University
Contraception
A Comparison of Short Interval vs. Routine Postpartum Visit on Contraceptive Initiation
The current postpartum care model of a single visit 4-6 weeks after delivery does not optimally address contraceptive needs. By this visit, many women have resumed sexual activity, potentially putting them at risk for unintended…
- Trial name
- NCT02769676
- Testing
- 3-week visit, usual care
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine