Clinical trials: Contraceptive Devices
HIV, Contraception
Darunavir and Rilpivirine Interactions With Etonogestrel Contraceptive Implant
This study will evaluate the pharmacokinetic properties of rilpivirine and darunavir when used in combination with etonogestrel
- Trial name
- DRIVE-1 (NCT03589040)
- Testing
- Etonogestrel 68Mg Implant, rilpivirine, darunavir
- Where
- Uganda
- Volunteers
- 60 people
- Sponsor
- Makerere University
Female Contraception, Contraception
Bioequivalence Study of the Oral Contraceptive Tablet Containing Norgestimate (NGM)/Ethinyl Estradiol (EE) With or Without Folic Acid in Healthy Women.
The purpose of the study is to determine the bioequivalence of NGM and EE in 2 formulations of 250 mcg NGM/35 mcg EE, 1 without folic acid and 1 containing 400 mcg folic acid.
- Conditions
- Female Contraception, Contraception, Therapeutic Equivalency, Pharmacokinetics
- Trial name
- NCT00709189
- Testing
- Norgestimate/Ehinyl Estradiol; Folic acid.
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Contraception
Study Assessing the Reduction of Pain Felt During Installation Intra- Uterine Device by Direct Technique
Intrauterine devices (IUDs) are contraceptive methods of long-acting (from 3 to 10 years depending on the model) and among the most effective.
- Trial name
- DIRECTE (NCT02595125)
- Testing
- IUD
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Contraception
Contraceptive Efficacy, Tolerance and Acceptability of a Benzalkonium Chloride Spermicide Cream In Women Aged Over 40 Years of Age
In spite of many advantages of spermicides, there is no contraceptive efficacy study conducted with any spermicide in women aged over 40 years.
- Trial name
- BZK40+ (NCT03102450)
- Testing
- Benzalkonium Chloride Spermicide Cream
- Where
- 15 sites in France, Russia
- Volunteers
- 151 people
- Sponsor
- Laboratoire Innotech International
Contraception Behavior, Contraception
The Influence of Trust in the Health Care System on Postpartum Contraceptive Choice
The purpose of this research is to understand the relationship between trust in the health care system and choice of contraception during the postpartum period among pregnant women receiving prenatal care.
- Trial name
- NCT02213874
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Contraception
Effects on Bone Mineral Density (BMD) of the Combined Oral Contraceptive NOMAC-E2 Compared to a COC Containing LNG/EE (292005)(P05765)(COMPLETED)
The primary purpose of this study is to evaluate the effects of the NOMAC-E2 combined oral contraceptive (COC) on bone mineral density (BMD).
- Trial name
- NCT00511342
- Testing
- NOMAC-E2, LNG-EE
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Contraception
Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring in Women at Risk for Pregnancy (MK-8342B-061)
The purpose of this study is to assess the contraceptive efficacy of the Etonogestrel (ENG) + 17β-Estradiol (E2) vaginal ring in women between 18 and 35 years of age based on the number of in-treatment pregnancies as expressed by…
- Trial name
- NCT02524288
- Testing
- ENG-E2 125 μg/300 μg vaginal ring
- Volunteers
- 1,941 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Contraception, Change in Bone Mineral Density
Efficacy, Safety, and Tolerability of LPRI-CF113 as an Oral Contraceptive in Females
This study will be in two parts, Part A and Part B. The primary objective of Part A is to evaluate the contraceptive efficacy of LPRI-CF113.
- Trial name
- NCT05461573
- Testing
- Drospirenone
- Where
- 47 sites in United States, Canada
- Volunteers
- 1,542 people, healthy volunteers welcome
- Sponsor
- Insud Pharma
Contraception
A Study to Assess Contraceptive Efficacy and Safety of Etonogestrel (ENG) Implant Beyond 3 Years of Use (MK-8415-060)
The primary purpose of this study is to assess the efficacy and safety of the etonogestrel (ENG) contraceptive implant during participants' fourth and fifth years of use when used as the only method of contraception.
- Trial name
- NCT04626596
- Testing
- Radiopaque Etonogestrel (ENG) Implant
- Where
- 67 sites in United States, Puerto Rico
- Volunteers
- 498 people
- Sponsor
- Organon and Co
Contraception
Bedsider.Org in Post-abortion Contraceptive Counseling: A Mixed Methods Study
This is a mixed methods study, incorporating a randomized controlled trial and a qualitative provider focus group, to evaluate contraceptive counseling aided by www.Bedsider.org in patients seeking first-trimester abortion.
- Trial name
- Bedsider (NCT02532946)
- Testing
- Bedsider.org counseling
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Contraception
Prospective Controlled Cohort Study on the Safety of a Monophasic Oral Contraceptive Containing Nomegestrol Acetate (2.5mg) and 17ß-estradiol (1.5mg)
This study compares the risks of short- and long-term use of NOMAC-E2 (containing a fixed dose of nomegestrol acetate and estradiol) compared with levonorgestrel-containing combined oral contraceptives (COC-LNG) in a study…
- Trial name
- PRO-E2 (NCT01650168)
- Where
- Germany
- Volunteers
- 101,498 people, healthy volunteers welcome
- Sponsor
- Center for Epidemiology and Health Research, Germany
Acne Vulgaris
Evaluate Safety and Efficacy of an OC Preparation vs Placebo for 6 Treatment Cycles in Women With Moderate Acne.
The objectives of this study were to evaluate the efficacy and safety of drospirenone 3 mg/ethinyl estradiol 0.02 mg (DRSP/EE) in comparison with placebo in female subjects with moderate acne vulgaris during 6 treatment cycles.
- Trial name
- NCT00651469
- Testing
- YAZ (DRSP 3 mg/EE 0.02 mg, BAY86-5300)
- Where
- 27 sites in United States
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- Bayer
Contraception, Family Characteristics
Evaluation of a Mass Media Family Planning Campaign on the Uptake of Contraceptive Methods in Burkina Faso
In this experiment, the investigators will study the effect of a mass media family planning campaign on contraception related behavior.
- Conditions
- Contraception, Family Characteristics, Family Size, Desired
- Trial name
- NCT02714686
- Testing
- Radio Mass Media Family Planning Campaign
- Where
- Burkina Faso
- Volunteers
- 7,515 people, healthy volunteers welcome
- Sponsor
- Abdul Latif Jameel Poverty Action Lab
Adherence to Oral Contraceptive Therapy
Effect of a Smartphone Application on Oral Contraceptive Adherence in College Females
This research study is to see if smartphone applications help college women remember to take birth control better than pharmacist consultation alone. Patients will participate in this study for 6 (six) months.
- Trial name
- NCT01947842
- Testing
- Smartphone App Dosecast
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Belmont University
Contraceptive Behavior, Internet Use
Evaluation of Internet Access and Use in Adolescent Women Initiating Contraception
This purpose of this study is determine whether the use of internet technology to communicate with adolescents about contraception is feasible and to determine whether it is more effective than traditional methods.
- Trial name
- NCT00333541
- Testing
- Using internet/E-mail for follow-up
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Contraception, Birth Control
Safety of a Contraceptive Copper Vaginal Ring
Many birth control options today come with unwanted side effects or risks. Hormonal methods can affect both mental and physical health, while devices like copper IUDs carry risks such as uterine perforation or infection.
- Conditions
- Contraception, Birth Control, Pregnancy Prevention
- Trial name
- NCT07666997
- Testing
- Vaginal Ring
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Elle, MD Biotechnologies Inc.
Sterility, Female, Contraception
Real World Effectiveness and Safety of Hysteroscopic (Essure®) Compared to Laparoscopic Sterilization
More than 345,000 U.S. women undergo either tubal ligation ("getting her tubes tied") or Essure procedures each year to permanently avoid pregnancy.
- Conditions
- Sterility, Female, Contraception, Contraceptive Device; Complications
- Trial name
- NCT03438682
- Testing
- Essure, Laparoscopic sterilization, Intrauterine Device (IUD)
- Where
- United States
- Volunteers
- 89,203 people, healthy volunteers welcome
- Sponsor
- Yale University
Underweight
The Effect of Hormonal Contraceptives on Breast-milk Production and Infant Growth
The investigators propose a randomized clinical trial comparing the effect of 30 mcg ethinyl estradiol and LNG 150 combination oral contraceptive pills versus placebo, or LNG-IUS or Etonogestrel-releasing contraceptive implant…
- Trial name
- NCT01388582
- Testing
- LNG-IUS, Implanon, 30 mcg EE and 150 LNG oral contraceptive (Microvlar)
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Postpartum Contraception, Reproductive Health
Predictors of PPIUCD Discontinuation at Two Years: A Clinical Study in Pakistan
This prospective cohort study evaluated the continuation rates, complications, and satisfaction associated with postpartum intrauterine contraceptive devices (PPIUCDs) as a long-acting reversible contraception (LARC) method.
- Conditions
- Postpartum Contraception, Reproductive Health, Family Planning
- Trial name
- NCT06766396
- Testing
- Postpartum Intrauterine Contraceptive Device (PPIUCD).
- Where
- Pakistan
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Glucose Homeostasis
Postprandial Glucose Handing in Contraceptive and IUD Users
Goals: The long-term use of hormonal birth control has been shown to effect glucose handling, or blood sugar regulation, and potentially lead to insulin resistance which increases a person's risk for metabolic diseases such as…
- Trial name
- HCPG (NCT07169591)
- Testing
- Oral Glucose Tolerance test (75g 2-hour)
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- McMaster University