Clinical trials: Contraceptive Devices
Contraception
Study on Safety and Efficacy of an Oral Contraceptive in Long Cycles
The purpose of the study is to determine safety and efficacy of long-cycle regimens of an oral contraceptive.
- Trial name
- NCT00266032
- Testing
- Flexible (extended) treatment of EE20/DRSP (YAZ, BAY86-5300), Fixed extended treatment of EE20/DRSP (YAZ, BAY86-5300), Standard 24+4 treatment of EE20/DRSP (YAZ, BAY86-5300)
- Where
- 35 sites in Canada, Germany and 1 more
- Volunteers
- 1,166 people, healthy volunteers welcome
- Sponsor
- Bayer
Reproductive Behavior, Family Planning Services
Effectiveness of Integrating Family Planning - Maternal, Newborn and Child Health (MNCH) Services on Uptake of Voluntary Modern Contraceptive Methods
Aim To evaluate the impact of an integrated Family Planning-Maternal,Newborn and Child Health service delivery model to increase coverage of MCM in a rural Pakistan.
- Trial name
- RMNCH FP (NCT05045599)
- Testing
- Capacity Building of Health care workers and providers to deliver integrated Family Planning and Maternal, Newborn and Child Health
- Where
- Pakistan
- Volunteers
- 125,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Healthy
A Study of Lanabecestat in Healthy Female Participants Taking Oral Contraceptive
The study will evaluate the effect of oral contraceptive (birth control pill) on the blood level of lanabecestat when both are given together. Side effects will be monitored and documented.
- Trial name
- NCT03506399
- Testing
- Lanabecestat, Oral Contraceptive
- Where
- Singapore
- Volunteers
- healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Pregnancy, Unplanned, Contraceptive Behavior
Group-based Life Skills and Health Empowerment for Married Women to Avoid Unintended Pregnancies in India
The goal of the cluster randomized trial is to evaluate the impact of a reproductive health and empowerment intervention (TARANG) compared to the standard of care health information (control group) on the prevalence of…
- Trial name
- TARANG (NCT06024616)
- Testing
- TARANG
- Where
- India
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Contraception, Ovulation Inhibition
Efficacy and Safety of Two Flexible Extended Regimens of BAY86-5300 (SH T00186D) in Comparison With the Conventional Regimen of YAZ
The purpose of this study is to determine whether the study drug is safe and effective.
- Conditions
- Contraception, Ovulation Inhibition, Contraceptives, Oral
- Trial name
- NCT00567164
- Testing
- EE20/DRSP (BAY86-5300), EE20/DRSP (YAZ, BAY86-5300)
- Where
- 85 sites in United States
- Volunteers
- 1,887 people, healthy volunteers welcome
- Sponsor
- Bayer
Contraception
Dose-finding Study of MR-130A-01 Contraceptive Transdermal Patch
A single-center, randomized, open-label, parallel-group, multi-arm, phase II clinical trial in healthy women aged 18 to 35 years who have a documented ovulatory cycle prior to randomization.
- Trial name
- NCT06048536
- Testing
- MR-130A-01 Transdermal patch
- Where
- Germany
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Mylan Pharmaceuticals Inc
Pregnancy
Oral Contraceptive Pills Compared to Vaginal Rings
The purpose of this study is to determine whether teens and young women would prefer the Nuvaring to oral contraceptive pills after having tried both methods.
- Trial name
- NCT00357526
- Testing
- OCPs, vaginal ring
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Contraceptive Usage
Immediate Versus Delayed Insertion of Implanon in Postpartum Adolescents
The specific aim of this study is to evaluate whether insertion of a long-acting contraceptive implant in postpartum adolescents prior to hospital discharge increases use of this highly effective contraception during the first…
- Trial name
- Implanon (NCT03585504)
- Testing
- Etonogestrel contraceptive implant
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Vestibulodynia
Hormonal Contraceptive Use and the Risk of Provoked Vestibulodynia
There have been reports in the medical literature demonstrating a link between the development of provoked vestibulodynia (PVD), a sexual pain disorder, and hormonal contraceptive (HC) use.
- Trial name
- NCT01741948
- Testing
- Hormonal contraceptive
- Where
- 2 sites in Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- ahinoam lev sagie
Peer Counseling, LARC Desire
Influence of Peer Mentoring on Adolescent Contraceptive Decision Making
This is a prospective, randomized-controlled trial in which subjects will be randomized to receive either routine contraceptive counseling or peer mentoring plus routine contraceptive counseling.
- Trial name
- ImPACCT (NCT02157285)
- Testing
- Peer Mentor Counseling
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Bacterial Vaginosis
Effects of a Vaginal Contraceptive Ring on Vaginal Microbiota and Local Immunity
To assess potential benefits associated with both intermittent (use for 3 weeks, remove for 1 week, as defined in the package insert) and continuous (use for 4 weeks, then replace) CVR use among women either with BV or at high…
- Trial name
- NCT02432404
- Testing
- NuvaRing
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Washington
Type 2 Diabetes Mellitus
The Effects of Exenatide on Oral Contraceptive Pharmacokinetics in Healthy Females
The purpose of this study is the examine the effect of taking exenatide on the blood levels (pharmacokinetics) of orally-administered contraceptives.
- Trial name
- NCT00254800
- Testing
- ethinyl estradiol and levonorgestrel; exenatide
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Bariatric Surgery Candidate
Contraception and Bariatric Surgery: Evaluation of Contraception and Contraceptive Knowledge of Women Undergoing Bariatric Surgery at the University Hospital of Reims
Obesity is a public health phenomenon affecting more than 17% of women in France, and more than 20% of men and women in Champagne-Ardenne.
- Trial name
- NCT04219852
- Testing
- data collection
- Where
- France
- Volunteers
- 100 people
- Sponsor
- CHU de Reims
Neural Tube Defects, Congenital, Hereditary, and Neonatal Diseases and Abnormalities
A Study to Evaluate Folate Levels in Women Taking Oral Contraceptives
The purpose of this study is to compare red blood cell folate levels in women who are taking oral contraceptives with or without folic acid
- Conditions
- Neural Tube Defects, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Nervous System Malformations
- Trial name
- NCT00301587
- Testing
- Norgestimate-ethinyl estradiol, with or without folic acid
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Contraception
Evaluation of a Novel and Simplified Technique for Intrauterine Contraceptive Devices Insertion: a Prospective Cohort Study
The intrauterine devices (IUDs) are a safe, reliable, long-acting and reversible contraceptive method. It is also sound safe and cheap contraceptive methods available and is nearly maintenance free for up to 10 years.
- Trial name
- NCT02841826
- Testing
- IUD, Uterine sounding, Transvaginal ultrasound
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Cardiovascular Diseases, Heart Diseases
Myocardial Infarction and Non-contraceptive Estrogen Use
To evaluate whether the use of noncontraceptive estrogen influenced the incidence of first myocardial infarction in women.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Myocardial Infarction, Menopause
- Trial name
- NCT00005185
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
HIV Infections, Contraception
A Crossover Acceptability Study Assessing a DPP Capsule for HIV and Pregnancy Prevention
The study design is a single-site, two-arm, randomized, open-label crossover trial in 30 AGYW aged 16-24 in Chitungwiza (Harare), Zimbabwe.
- Trial name
- 952 (NCT04778514)
- Testing
- Dual Prevention Pill, PrEP and combined oral contraceptive (COC) as two separate tablets
- Where
- Zimbabwe
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Population Council
Contraception, Reproductive Behavior
Patient-centered Information on Permanent Contraception
The goal of this study is to understand whether providing information to women with a strong desire to avoid future pregnancy about how tubal sterilization compares to long-acting reversible contraceptives improves perceived…
- Conditions
- Contraception, Reproductive Behavior, Contraception Behavior
- Trial name
- NCT06296797
- Testing
- Control arm: Existing educational website, Advancing Access Website
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Contraception
Study to Evaluate the Safety and Efficacy of Two Contraceptive Vaginal Rings Delivering a Daily Dose of 1500 or 2500 μg of CDB-2914
The purpose of this study is to to determine pharmacodynamic effects of a vaginal ring delivering either 1,500 or 2,500 μg of CDB-2914 per day during 6 months of treatment on: 1. follicular function and inhibition of ovulation 2.
- Trial name
- NCT00791297
- Testing
- CDB-2914
- Where
- 3 sites in United States, Chile and 1 more
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Population Council
Combined Oral Contraceptive Cessation
CBG Normalization After Discontinuation of COC's
In this study, the investigators aim to examine after which duration corticosteroid-binding globulin (CBG) and total cortisol concentrations return to normal after cessation of the combined oral contraceptive pill in healthy…
- Trial name
- NCT06802211
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)