Clinical trials: Contraceptive Devices
Contraception Behavior
A Pilot Study to Estimate the Impact of a Screening and Referral Service on Contraceptive Use
The specific aim of this pilot study is to estimate the impact of a new digital health service on the uptake of family planning among Kenyan women with an unmet need for contraception.
- Trial name
- E0108 (NCT03224390)
- Testing
- digital family planning screening and referral service
- Where
- Kenya
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Duke University
Hypothalamic-pituitary-ovarian Axis, Gonadotropins, Ethinyl Estradiol, Contraceptive Efficacy
Oral Contraceptive Hormone-free Interval Pituitary/ Ovarian Activity
The degree of suppression and subsequent activation of the hypothalamic-pituitary-ovarian axis during the hormone-free interval in combined oral contraceptive (COC) hormone users varies depending on the dose of ethinyl estradiol…
- Trial name
- NCT01953211
- Testing
- combined oral contraceptives
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Southern California
Oral Contraceptive
Oral Contraceptive (OC) Estrogen Dose and Breast Proliferation
The purpose of this research study is to gain a better understanding of the changes that may occur in the breast when a woman uses an oral contraceptive (birth control pill).
- Trial name
- OCP2 (NCT01318005)
- Testing
- Oral Contraceptive: Ortho-Novum® 1/35, Oral Contraceptive: Ovcon® 35, Oral Contraceptive: Microgestin Fe® 1/20
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Healthy
A Study in Healthy Women to Test Whether BI 1358894 Influences the Amount of a Contraceptive in the Blood
This study aims to investigate the effect of multiple doses of BI 1358894 on pharmacokinetics of ethinylestradiol (EE) and drospirenone (DRSP) (Yasmin®)
- Trial name
- NCT05934942
- Testing
- Yasmin®, BI 1358894
- Where
- Germany
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Postpartum
Home-based Delivery of the Contraceptive Implant in Postpartum Guatemalan Women
Abstract Background: Postpartum contraception is important to prevent unintended and closely spaced pregnancies following childbirth.
- Trial name
- NCT04005391
- Testing
- Offer of Participant's Choice of Contraception Method
- Where
- 2 sites in United States, Guatemala
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Contraception
Study of the Use of a Contraceptive Vaginal Ring (NuvaRing) in Normal Daily Practice in Indian Women (P07733)
This study will collect information on cycle control, acceptability and tolerability of the vaginal contraceptive ring (NuvaRing) as used in normal daily practice by Indian women.
- Trial name
- NCT01490190
- Testing
- Ethinylestradiol + Etonogestrel Vaginal Ring (NuvaRing)
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Organon and Co
PCOS
Comparing the Effects of Oral Contraceptive Pills Versus Metformin
To determine the effect of Oral Contraceptive Pills (OCP) verses Metformin verses OCP and Metformin on the prevalence of Metabolic Syndrome (MetS) and its components in overweight/obese women with Polycystic Ovary Syndrome…
- Trial name
- COMET-PCOS (NCT03229057)
- Testing
- OCP + Metformin
- Where
- 2 sites in United States
- Volunteers
- 240 people
- Sponsor
- Anuja Dokras
Dysmenorrhea
A Study to Evaluate the Efficacy of Seasonique for the Treatment of Cyclic Pelvic Pain
This study is being conducted to evaluate the effects of treatment with Seasonique an extended-regimen oral contraceptive that utilizes low dose ethinyl estradiol during the typical hormone-free interval.
- Trial name
- NCT00196313
- Testing
- levonorgestrel/EE 0.15/0.03 and EE 0.01 mg tablets
- Where
- 13 sites in United States
- Volunteers
- 95 people
- Sponsor
- Duramed Research
Contraception Behavior
Premature Discontinuation of Contraceptive Implants
To compare rates of etonogestrel implant discontinuation in implant initiators who are given advance provision of combined oral contraceptive pills (COCs) and a bleeding rescue regimen (COCR intervention) to participants given…
- Trial name
- NCT04828824
- Testing
- Ethinyl Estradiol / Norgestimate Oral Tablet
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Contraceptive Usage, Vaginal Epithelial Disruption
Hormonal Contraception and Vaginal Health
The purpose of this study is to help determine if the route by which women receive hormonal contraception causes different changes to occur in the lining of the vagina.
- Trial name
- NCT00612508
- Testing
- Desogen (ethinyl estradiol and desogestrel), NuvaRing (ethinyl estradiol and etonogestrel)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Acne Vulgaris
An Efficacy and Safety Study Comparing Oral Contraceptive Containing Norgestimate or Desogestrel for Acne Treatment
The purpose of this study is to evaluate the efficacy and safety of Ethinyl estradiol and Norgestimate (EE/NGM) compared to Ethinyl estradiol and Desogestrel (EE/DSG), for treatment of female participants with mild to moderate…
- Trial name
- NCT01466673
- Testing
- Ethinyl estradiol/Norgestimate (EE/NGM), Ethinyl estradiol/Desogestrel (EE/DSG)
- Where
- 3 sites in Thailand
- Volunteers
- 201 people
- Sponsor
- Janssen-Cilag Ltd.,Thailand
Post Abortion Care
Contraceptive Counseling Following an Abortion
The purpose of this study is to determine whether contraceptive counseling is effective on acceptance and use of methods in women following an abortion.
- Trial name
- APA (NCT00756314)
- Testing
- Personalized contraceptive counseling
- Where
- Brazil
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Prevention of Pregnancy
Study of Safety and Efficacy of an Oral Contraceptive
This is a comparative study. The primary objective of the study is to assess the efficacy of a low dose oral contraceptive in the prevention of pregnancy.
- Trial name
- NCT00932321
- Testing
- Norethindrone Acetate/Ethinyl Estradiol 24 Days, Norethindrone Acetate /Ethinyl Estradiol 21 Days
- Where
- 34 sites in United States
- Volunteers
- 938 people, healthy volunteers welcome
- Sponsor
- Warner Chilcott
Contraception
Desogestrel-containing COCP Pharmacokinetic Validation Study
This study aims to validate prior pharmacokinetic research with combined oral contraceptive pill users that supports utilizing a 24-hour trough concentration as an accurate proxy for the intensive pharmacokinetic parameter of…
- Trial name
- NCT05002738
- Testing
- Desogestrel and Ethinyl Estradiol Tablets
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Infertility, In-vitro Fertilization
NuvaRing vs. Oral Contraceptive Pills (OCP) for In-Vitro Fertilization (IVF) Pre-treatment
The newly designed contraceptive ring, Nuvaring has a lower total steroid dose, and medications are delivered locally. It has been proven to be as safe and effective as the combined OCP in ovarian suppression and preventing…
- Trial name
- NCT01298128
- Testing
- NuvaRing, marvelon
- Volunteers
- 70 people
- Sponsor
- University of Toronto
Contraception, Malposition of Intrauterine Contraceptive Device
LNG-IUS at 2 Weeks Postpartum
This is a study of 50 postpartum women interested in having the Mirena® LNG-IUS placed for contraception. The Mirena® is an FDA approved intrauterine contraceptive device that provides contraception for 5 years with excellent…
- Trial name
- LNG-IUS (NCT02121067)
- Testing
- Levonorgestrel Intrauterine System (LNG-IUS)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Contraception
E4 FREEDOM (Female Response Concerning Efficacy and Safety of Estetrol/Drospirenone as Oral Contraceptive in a Multicentric Study) - EU/Russia Study
The objectives of this study are to evaluate the contraceptive efficacy, vaginal bleeding pattern (cycle control), and the general safety and acceptability of the 15 mg estetrol (E4)/3 mg drospirenone (DRSP) combination in…
- Trial name
- NCT02817828
- Testing
- 15 mg E4/3 mg DRSP
- Where
- Belgium
- Volunteers
- 1,577 people, healthy volunteers welcome
- Sponsor
- Estetra
Contraception, Decision Making
Computerized Contraceptive Decision Aid
The purpose of this study is to conduct a randomized clinical trial of a web-based contraceptive decision aid compared to routine contraceptive counseling to evaluate the effect of the contraceptive decision aid on the…
- Conditions
- Contraception, Decision Making, Satisfaction, Evaluation
- Trial name
- CDM RCT (NCT01479985)
- Testing
- CDM Tool
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Bone Mineral Density
A Multicenter Study to Evaluate the Effects of a 91-day Oral Contraceptive on Bone Mineral Density in Adolescent Females
This study is being conducted to compare the effects of a 91-day oral contraceptive (OC) to a 28-day OC regimen on bone mineral density (BMD) in adolescent females.
- Trial name
- NCT00924560
- Testing
- 91-day Levonorgestrel Oral Contraceptive, 28-day Levonorgestrel Oral Contraceptive
- Where
- 46 sites in United States
- Volunteers
- 1,361 people, healthy volunteers welcome
- Sponsor
- Duramed Research
Relapsing Multiple Sclerosis (RMS)
Effects of Cladribine Tablets on the PK of Microgynon®
The purpose of this study was to investigate the potential effects of cladribine on the pharmacokinetics (PK) of monophasic oral contraceptive microgynon® by assessment of its constituents, ethinyl estradiol (EE) and…
- Trial name
- NCT03745144
- Testing
- Cladribine, Microgynon®
- Where
- 7 sites in Germany, Poland
- Volunteers
- 28 people
- Sponsor
- Merck KGaA, Darmstadt, Germany