Clinical trials: Contrast Agent
Coronary Artery Disease, Healthy
Evaluation and Optimization of PB127 Myocardial Perfusion Echocardiography on Ultrasound Systems
The purpose of this clinical trial is to evaluate various commercially available ultrasound systems and to identify imaging parameters to be used with these systems (along with the contrast agent PB127) as well as to further…
- Trial name
- NCT00487903
- Testing
- PB127 for Injectable Suspension
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Point Biomedical
Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc)
Interventional AI-Human Collaboration for Liver Tumor Diagnosis
Recent advances in artificial intelligence (AI), particularly deep learning technology, have transformed medical imaging analysis.
- Conditions
- Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc), Hepatic Metastasis, Hepatic Hemangioma
- Trial name
- NCT07153783
- Testing
- AI-human collaboration for CE-CTs diagnosis
- Where
- China
- Volunteers
- 10,333 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Healthy
A Healthy Volunteer Trial Investigating MR-enterography Image Quality of Lumentin® 44
A healthy volunteer, open, PoC single center trial investigating a new oral contrast agent for use in combination of MR examination of the abdomen and pelvis.
- Trial name
- NCT05781490
- Testing
- Lumentin® 44 Powder for oral foam
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Lument AB
Healthy, Coronary Artery Disease
Dose Finding Study of PB127 Ultrasound Contrast Agent in Healthy Volunteers and Patients With Coronary Artery Disease
The purpose of this study is to determine the dose of PB127 for detection and/or exclusion of coronary artery disease when used with cardiac ultrasound. This study also evaluates the safety of PB127.
- Trial name
- NCT00584818
- Testing
- PB127 for Injectable Suspension
- Where
- 16 sites in United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Point Biomedical
Mucogingival Defect
Blood Flow Analysis of the Human Mucosa After Vestibuloplasty Procedures
Apply the LSCI for follow-up the postoperative microcirculation after surgical procedures to enlarge keratinized gingiva in order to characterize the kinetics of the blood flow changes during wound healing in human subjects.
- Trial name
- NCT02975024
- Testing
- laser speckle contrast imaging of the oral mucosa, wound fluid measurement, quantitative determination of VEGF
- Where
- Hungary
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Thyroid Dysfunction
Serum Thyroid Function After Iodinated Contrast Administration
This study investigated the changes in serum thyroid function and urinary iodine levels before and after the use of iodinated contrast to analyze the prevalence of thyroid dysfunction in the Chinese euthyroid adults after using…
- Trial name
- NCT05786846
- Testing
- Iodinated contrast agents
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Contrast Enhanced Mammography-guided Biopsy
Clinical Evaluation of CEM-guided Biopsy
CEM-guided biopsy is an optional accessory of Senographe Pristina intended to provide accurate location of lesions in the breast in three dimensions, using information obtained from Contrast Enhanced Mammography (CEM) images.
- Trial name
- NCT05250674
- Testing
- CEM-guided biopsy
- Where
- Spain
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Glaucoma
Assessment of Ability Related to Vision
To determine the clinical usefulness of a refined third-generation instrument - The Assessment of Ability Related to Vision (AARV) in establishing the amount of disability, charting the detrimental effects of progressive disease…
- Trial name
- AARV (NCT01027312)
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Renal Cell Carcinoma
Yorkshire Kidney Screening Trial
Kidney cancer is the 8th most common cancer in Yorkshire. It has a poor survival rate, with only 6 out of 10 patients diagnosed with kidney cancer still alive after 5 years.
- Trial name
- YKST (NCT05005195)
- Testing
- Low dose abdominal computed tomography scan
- Where
- United Kingdom
- Volunteers
- 5,850 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Healthy
A Study to Evaluate Laser Speckle Contrast Imaging to Assess Changes in Chemical Agent-Induced Skin Blood Flow in Healthy Participants (MK-0000-420)
Pain is a significant issue and there is a need for better treatments for pain management. Local changes in skin blood flow can be used as an indicator of pain in the body.
- Trial name
- NCT06809569
- Testing
- Allyl Isothiocyanate (AITC), Capsaicin, Vehicle for AITC
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Carotid Artery Disease
3D Multi-Contrast Atherosclerosis Characterization of the Carotid Artery
This is a technical development study with the goal to develop 3D techniques for atherosclerosis plaque characterization. We hypothesize that 3D MRI is superior to 2D MRI in characterizing major plaque constituents that…
- Trial name
- NCT02163408
- Testing
- MRI with/without contrast
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Athletic Performance, Neuromuscular Adaptations
Neuromuscular Adaptations Following Eight Weeks of French Contrast Training in Elite Youth Football Players: Implications for Athlete Health and Performance
This randomized controlled trial aimed to investigate the effects of an 8-week French Contrast Training (FCT) intervention on reactive strength index (RSI), sprint performance, and anaerobic profile in elite youth football players
- Trial name
- Unlocking PAPE (NCT07511348)
- Testing
- French Contrast Training + Standard football training (8 weeks), Control
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Cardiovascular Diseases, Vascular Diseases
The Effects of Iontophoresed Vasoactive Drugs on Cutaneus Blood Flow
Many acute and chronical medical conditions, such as, shock, sepsis, diabetes, hypertonia, and cardiovascular disease are associated with a perturbated or lost ability of regulating the diameter of the blood vessels.
- Trial name
- Jonto01 (NCT04777383)
- Testing
- Acetylcholine, Norepinephrine, Phenylephrine
- Where
- Sweden
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Peripheral Artery Disease
Contrast Ultrasound Perfusion Imaging in PAD With Sonazoid
The measurement of limb skeletal muscle perfusion and perfusion reserve during exercise is an approach that can assess the total impact of the complex pathophysiologic processes in patients with limb ischemia, particularly in…
- Trial name
- NCT02398266
- Testing
- Contrast ultrasound of leg muscle with Sonazoid (Contrast ultrasound microvascular perfusion imaging)
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Contrast Enhancement on Cardiac CT
Comparison of Contrast Agents During CT Angiography
The purpose of this study is to compare the effects of a certain contrast agent (iodixanol) to two other commonly used contrast agents called Iopamidol (Isovue) and iohexol (Omnipaque), on heart and kidney safety in patients…
- Trial name
- Visipaque (NCT01534975)
- Testing
- contrast agent
- Where
- United States
- Volunteers
- 513 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Lower-Limb Explosive Performance
French Contrast Training in Male Collegiate Basketball Players
This randomized controlled trial evaluated the effects of 12 weeks of French Contrast Training (FCT) compared with traditional resistance training (RT) on lower-limb explosive performance in male collegiate basketball players.
- Trial name
- NCT07776808
- Testing
- French Contrast Training, Resistance Training
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ziren Zhao
Alzheimer Disease, Dementia
Evaluation of Age- and Alzheimer's Disease-Related Memory Disorder
The purpose of this study is to examine how a part of the brain called the hippocampus contributes to memory changes that occur with aging and Alzheimer's disease (AD). Memory problems are the most important early symptoms of AD.
- Conditions
- Alzheimer Disease, Dementia, Memory Disorder, Healthy
- Trial name
- NCT00029120
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Low Vision
Obstacle Negotiation in Older People With and Without Vision Impairment
Falls are common among people with vision impairment and can lead to devastating health consequences. Understanding the functions of vision and how the visual characteristics of obstacles in the walking path impact the gait of…
- Trial name
- NCT05888441
- Testing
- Obstacle characteristics
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Indiana University
Gd-based Contrast Media Exposure During Breast MRI Scans
Evaluation of Gadolinium Deposits in Healthy Women Participating in a High Risk Screening Program for Early Breast Cancer Detection
Purpose: To determine whether patients at high risk to develop breast cancer having received at least 6 cumulative dosages of macrocyclic Gd-based contrast media in the context of breast cancer screening by means of…
- Trial name
- NCT03393442
- Testing
- Brain MRI scan
- Where
- Austria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Cataract, Pseudophakia
Wavefront Analisys and Contrast Sensitivity of Spherical and Aspherical Intraocular Lenses
Purpose:To compare visual performance, total and high order wavefront aberrations (coma, spherical aberration and other terms) and contrast sensitivity in eyes implanted with one monofocal aspheric intraocular lens (IOL) and two…
- Trial name
- NCT00347243
- Testing
- phacoemulsification (cataract surgery)
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Federal University of São Paulo