Clinical trials: Contrast Agent
Coronary Artery Disease
A Low-dose Radiation and Contrast Agent Exposure Protocol for Coronary CTA in Diabetic Patients
To assess diagnostic accuracy,image quality and renal safety of a double low-dose coronary CTA protocol at coronary artery evaluation in patients with diabetes by using invasive coronary angiography(ICA) as the reference method…
- Trial name
- NCT04342455
- Testing
- double-low scanning
- Where
- China
- Volunteers
- 400 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Kidney Transplantation
Contrast-Enhanced Ultrasound for Kidney Transplant
Contrast-enhanced ultrasound (CEUS) is a promising non-invasive imaging tool that may aid in the early detection of kidney transplant complications, such as delayed graft function (DGF) and acute allograft rejection.
- Trial name
- NCT02911714
- Testing
- Lumason Contrast-Enhanced Ultrasound
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Utah
Healthy Volunteers
The Effect of Contrast Media on Erythrocytes in Healthy Volunteers
The purpose of the study is to test the effect that contrast media (dye) has on cellular integrity (structure)
- Trial name
- NCT00285506
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Small Bowel Obstruction
Clinical Impacts of Oral Gastrografin Follow Through in Adhesive Small Bowel Obstruction (SBO)
Mini abstract : Altogether 100 patients with 117 episodes of ASBO were randomized into control and gastrografin groups. Eight episodes in eight patients were excluded.
- Trial name
- NCT00738855
- Testing
- Oral Gastrografin, Nothing per os
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Glaucoma
Visual Function Changes After Intraocular Pressure Reduction
During the glaucomatous disease process, subpopulations of cells may be dead, damaged or healthy. Visual function changes could be observed due to a recovering of the suffering ganglion cells after the intraocular pressure…
- Trial name
- NCT00435058
- Testing
- timolol maleate 0,5%, brimonidine tartrate 0,2%, travoprost 0,004%
- Volunteers
- 54 people
- Sponsor
- University of Sao Paulo
Breast Cancer Female, Breast Cancer
Tomosynthesis vs. Contrast-Enhanced Mammography in Women With Personal History of Breast Cancer in Western Pennsylvania
This is a prospective clinical trial that will examine if contrast-enhanced mammography substantially improves breast cancer detection compared to mammography with tomosynthesis, with minimal increase in false-positives, in women…
- Conditions
- Breast Cancer Female, Breast Cancer, Breast Neoplasms, Neoplasms
- Trial name
- TOCEM (NCT04085510)
- Testing
- Contrast-enhanced mammogram
- Where
- 3 sites in United States
- Volunteers
- 1,647 people, healthy volunteers welcome
- Sponsor
- Wendie Berg
Liver Metastases, Colon Cancer
Pilot 3D Contrast-Enhanced Ultrasound Imaging to Predict Treatment Response in Liver Metastases
Patients are invited to participate in a research study of liver perfusion (how blood flows to the liver over time). Researchers hope to learn whether perfusion characteristics of liver metastases may be predictive of response to…
- Trial name
- NCT01631318
- Testing
- Dynamic contrast-enhanced ultrasound imaging, Optical Tracking Device, Electromagnetic Tracking Device
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Stanford University
Endometriosis, Rectum
Bowel Preparation Before 3D Rectal Water Contrast Transvaginal Ultrasonography for Rectosigmoid Endometriosis
Three-dimensional (3D) rendering may be employed during transvaginal rectal water-contrast transvaginal ultrasonography (RWC-TVS) for detecting the presence and describe the characteristics of rectosigmoid endometriosis.
- Trial name
- NCT04406155
- Testing
- 3D-RWC-TVS with bowel preparation, 3D-RWC-TVS without bowel preparation
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Piazza della Vittoria 14 Studio Medico - Ginecologia e Ostetricia
End-stage Renal Disease, Renal Replacement Therapy
Can High Convection Volumes be Achieved in Each Patient During Online Post-dilution Hemodiafiltration?
Two recent randomized controlled trials (RCT) on online hemodiafiltration (HDF) did not show a treatment effect on patient survival when compared with low- or high-flux hemodialysis.
- Conditions
- End-stage Renal Disease, Renal Replacement Therapy, Hemodiafiltration, Convection Volume
- Trial name
- NCT01877499
- Testing
- Optimization of HDF key parameters
- Where
- 7 sites in Netherlands
- Volunteers
- 86 people
- Sponsor
- Amsterdam UMC, location VUmc
HCC, Hepatocellular Carcinoma
CEUS vs. AMRI for HCC Detection in Patients With Indeterminate Liver Nodules
The study will be conducted at the following locations: 1. UT Southwestern Medical Center 2. Parkland Health and Hospital System 3.
- Trial name
- NCT06184152
- Testing
- CEUS imaging, aMRI imaging
- Where
- 2 sites in United States
- Volunteers
- 600 people
- Sponsor
- University of Texas Southwestern Medical Center
Allergic Reaction to Contrast Media, Hypersensitivity Reaction
1-hour Premedication for Allergy Goal in Emergency: PAGE-1 Study
1-hour Premedication for Allergy Goal in Emergency: PAGE-1 is a prospective, parallel, two-arm, non-inferiority, randomized controlled trial evaluating the safety of a 1-hour (intervention) versus a 4-hour (standard regimen)…
- Conditions
- Allergic Reaction to Contrast Media, Hypersensitivity Reaction, Computed Tomography, Premedication
- Trial name
- PAGE1 (NCT07268248)
- Testing
- IV glucocorticoid and antihistamine, IV glucocorticoid and antihistamine (standard of care)
- Volunteers
- 540 people
- Sponsor
- Paul Peng, MD PhD MSCR
Coronary Artery Disease
Identification of Adverse Plaque Characteristics by Coronary MR Angiography
This is a pilot study to determine whether coronary magnetic resonance angiography(CMRA)can identify adverse plaque characteristics (buildup of fat, cholesterol, calcium, and other substances found in the blood) seen on coronary…
- Trial name
- NCT01986868
- Testing
- Coronary MR Angiography (CMRA)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Cedars-Sinai Medical Center
Endometriosis, Sigmoid, Endometriosis, Rectum
Three-dimensional (3D) Rectal Water Contrast Transvaginal Ultrasonography Versus Computed Colonography in the Diagnosis of Rectosigmoid Endometriosis
Rectosigmoid involvement by endometriosis causes intestinal symptoms such as constipation, diarrhea, and dyschezia. A non-invasive diagnosis of bowel endometriosis is relevant to provide the patients information on the potential…
- Trial name
- NCT04295343
- Testing
- Three-dimensional (3D) rectal water contrast transvaginal ultrasonography, Computed colonography
- Where
- Italy
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ospedale Policlinico San Martino
Taste, Altered
Flavoring Oral Contrast for MR Enterography
To determine if patient satisfaction, participation, and image quality improves with flavored oral contrast for MR enterography.
- Trial name
- NCT02617576
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota
Intracranial Pathology, Intracranial Hypertension
Clinical Efficacy of a Non-Invasive Measure of Intracranial Pressure
This study is designed to evaluate the accuracy of a non-invasive method phase-contrast magnetic resonance imaging (MR-ICP) for assessing intracranial pressure (Phase 1).
- Trial name
- MR-ICP (NCT03212976)
- Testing
- Phase contrast magnetic resonance imaging
- Where
- 2 sites in United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Miami
Breast Cancer
Dual-energy Contrast-enhanced (2D and 3D Mammography Versus Contrast-enhanced MRI)- A Pilot Study
This is a pilot study to evaluate 2D contrast-enhanced mammography image and 3D (tomosynthesis) contrast-enhanced images to contrast enhanced MRI in women with greater than 95% probability of breast cancer (BIRADS 5) or confirmed…
- Trial name
- NCT01433640
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hologic, Inc.
Healthy Volunteers
Imaging Techniques in CT: Technical Development
Background: Computed tomography (CT) scanning is a procedure that helps doctors with diagnoses. It uses X-ray radiation to produce an image in three dimensions.
- Trial name
- NCT02242448
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Embolism, Pulmonary
Detection of Pulmonary Embolism With Low-dose CT Pulmonary Angiography
Computed tomography pulmonary angiography (CTPA) is the imaging method of choice to rule out acute pulmonary embolism based on its high sensitivity and specificity.
- Trial name
- REDOPED (NCT01258140)
- Testing
- Computed tomography pulmonary angiography
- Where
- Switzerland
- Volunteers
- 504 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cataract and IOL Surgery
Clareon PanOptix Versus AcrySof PanOptix : Prospective Study Comparing Contrast Sensitivity
Retrospective, comparative, interventional, randomized, single-center study, contralateral (the patient's 2 eyes will be implanted: 1 CPO and the other APO) Patients presenting for cataract surgery with a request for presbyopia…
- Trial name
- CLAYRE (NCT07158177)
- Testing
- Acrysof™ PanOptix™ toric or not, trifocal IOL CE marked, Alcon company., Clareon Panoptix
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Focal Liver Lesions
Phase 4 Paediatric Study to Evaluate Sonazoid Safety and Efficacy for Contrast-Enhanced Ultrasound Liver Imaging
Liver tumours, 40% of which are benign, account for 1% to 4% of all solid tumours in children. The benign tumours are mainly haemangiomas, liver hamartomas, and liver cell adenomas.
- Trial name
- NCT06639828
- Testing
- Contrast-Enhanced Ultrasound
- Where
- 6 sites in Germany, Italy and 1 more
- Volunteers
- 50 people
- Sponsor
- GE Healthcare
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