Clinical trials: Contrast Agent
Thyroid Nodules
Contrast-enhanced Ultrasound-guided Fine-needle Aspiration Biopsy in the Evaluation of Thyroid Nodules
To evaluate the application value of contrast-enhanced ultrasound in the diagnosis of thyroid nodules using fine needle aspiration.
- Trial name
- NCT03102099
- Testing
- contrast-enhanced ultrasound group, conventional ultrasound group
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Peking University Third Hospital
Hepatocellular Carcinoma
Accuracy of Contrast-Enhanced Ultrasound for Hepatocellular Carcinoma Post TACE
The purpose of this research study is to find out if a different type of imaging study called contrast enhanced ultrasound (CEUS) is as good as, or better than CT or MRI in patients diagnosed with hepatocellular carcinoma (HCC)…
- Trial name
- TACE (NCT04569799)
- Testing
- Lumason
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Milton S. Hershey Medical Center
Pancreas Cancer
Three New Methods for Diagnosing Pancreas Cancer
The purpose of this project is to evaluate and compare three new methods for diagnosis, staging, operability evaluation and treatment control of pancreas cancer.
- Trial name
- NCT00259532
- Testing
- Ultrasound and contrast agent
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Copenhagen
Aneurysm, AVM, Dural Arteriovenous Fistula, Glioma, Meningioma, Metastasis, Bypass
Intraoperative Laser Speckle Contrast Imaging of Cerebral Blood Flow
The purpose of the proposed study is to investigate the usefulness of laser speckle contrast imaging (LSCI) compared to indocyanine green angiography (ICGA).
- Trial name
- NCT05305378
- Testing
- Laser speckle contrast imaging (LSCI)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Dynamic Light
Malignant Melanoma
Sentinel Node With Ultrasound Contrast in Melanoma
The purpose is to evaluate,in 20 patients, if the sentinel node(s) in melanoma can be detected by lymph contrast ultrasound. In comparing the patients will also get lymph-scintigraphy and sentinel node detection wiht blue dye.
- Trial name
- NCT00370136
- Testing
- ultrasound contrast
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pancreatic Cancer
A Study of Nimotuzumab Combinated With Gemcitabine in K-RAS Wild-type Locally Advanced and Metastatic Pancreatic Cancer
Nimotuzumab is a humanized monoclonal antibody against epidermal growth factor receptor (EGFR). Clinical trials are ongoing globally to evaluate Nimotuzumab in different indications.
- Trial name
- NCT02395016
- Testing
- nimotuzumab, Gemcitabine
- Where
- 25 sites in China
- Volunteers
- 90 people
- Sponsor
- Biotech Pharmaceutical Co., Ltd.
Aortic Valve Stenosis, Renal Insufficiency
Remote Ischemic Preconditioning for Renal Protection in TAVI
Severe aortic stenosis remains a major cause of morbidity and mortality of the elderly affecting approximately 3% of elderly patients with an increasing number of patients undergoing transcatheter aortic valve interventions.
- Conditions
- Aortic Valve Stenosis, Renal Insufficiency, Contrast-induced Nephropathy
- Trial name
- NCT03347032
- Testing
- Remote ischemic preconditioning, Control
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Henry Ford Health System
Contrast-Induced Nephropathy, Acute Myocardial Infarction
Contrast Nephropathy Prevention With N-Acetylcysteine in Acute Myocardial Infarction
Patients with acute myocardial infarction undergoing primary angioplasty are at high risk for renal injury due to the toxic effect of contrast agents.
- Trial name
- NCT00237614
- Testing
- intravenous and oral N-acetylcysteine
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Milan
Chronic Renal Insufficiency, Serum Creatinine Concentration
MESNA for Prevention of Acute Deterioration of Renal Function Following Contrast Agent Application
The purpose of this study is to determine wether Mesna could prevent contrast-induced nephropathy
- Conditions
- Chronic Renal Insufficiency, Serum Creatinine Concentration, Contrast Media Exposition
- Trial name
- NCT00223548
- Testing
- sodium 2-mercaptoethane sulfonate
- Where
- Germany
- Volunteers
- 106 people
- Sponsor
- University of Ulm
Patients Undergoing Contrast Enhanced Multidetector Computed Tomography of the Chest, Abdomen, Liver or Aorta for Any Diagnostic Cause
Multidetector Computed Tomography (MDCT) Tailored Protocol
Collection of data from different sites regardless of whether they use standard or tailored protocols for the application of high concentration iodinated contrast agents to assess if the individually patient-adapted protocols…
- Trial name
- NCT01737333
- Where
- 2 sites in United States, Italy
- Volunteers
- 1,493 people
- Sponsor
- Bracco Diagnostics, Inc
Abdominal Neoplasm, Abdominal Injury
Pediatric Intravenous Contrast-Enhanced Ultrasound(CEUS) in China
The goal of this clinical trial is to evaluate the application of intravenous contrast-enhanced ultrasound examination in children with intra-abdominal diseases that require clear diagnoses.
- Conditions
- Abdominal Neoplasm, Abdominal Injury, Ascites
- Trial name
- CEUS (NCT07113808)
- Testing
- contrast-enhanced ultrasound examination, SonoVue®
- Where
- China
- Volunteers
- 108 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Contrast-induced Nephropathy
Predictive Value of CHA2DS2-VASC Score and Contrast Volume to Creatinine Clearance Ratio in Relation to Mehran Score for Contrast-Induced Nephropathy In ST- Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention
all patient presented with ST elevated myocardial infarction and underwent PPCI will be calculated with CHA2DS2-VASC score and contrast volume / creatinine clearance as apredictive value for Contrast induced nephropathy and the…
- Trial name
- NCT03266458
- Testing
- Primary percutaneous coronary intervention
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Assiut University
Breast Cancer
Non-contrast DWI for Supplemental Screening
Diffusion-weighted imaging (DWI) is a short (under 5 minutes) non-contrast MRI technique that has shown promise for the detection and characterization of breast cancer.
- Trial name
- NCT03607552
- Testing
- Non-contrast DWI, Non-contrast MRI
- Where
- 2 sites in United States
- Volunteers
- 269 people
- Sponsor
- University of Washington
Liver Neoplasms
Assessment of Indocyanine Green as a Near-Infrared Fluorescent Contrast Agent for Image-guided Liver Surgery
This is a prospective, monocentric, non-randomized, phase I-II study. The goal is to assess the faisability and the capabilities of fluorescence imaging in hepatic surgery, and specially to help the surgeon while performing liver…
- Trial name
- HEPATOFLUO (NCT01738217)
- Testing
- Fluobeam
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Centre Leon Berard
Tetralogy of Fallot, Pulmonary Insufficiency
Contrast Enhanced 3D Echocardiographic Quantification of Right Ventricular Volumes in Repaired CHD
We propose the novel integration of two echocardiographic technologies - three-dimensional echocardiography using semi-automated right ventricular analysis coupled with the administration of ultrasound enhancing agents - to…
- Trial name
- NCT05186415
- Testing
- Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Injection Powder for Suspension [LUMASON]
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Nemours Children's Clinic
Cataract, Lens Opacities
PMCF Study on Monofocal Toric IOL (PODEYE TORIC) in Asia
This is a single-center, prospective, open-label PMCF study whereby patients undergoing routine cataract surgery will have mono- or bilateral implantation of hydrophobic acrylic monofocal toric intraocular lens PODEYE TORIC…
- Conditions
- Cataract, Lens Opacities, Astigmatism
- Trial name
- PHY2102 (NCT04778501)
- Testing
- IOL implantation experimental
- Where
- Philippines
- Volunteers
- 45 people
- Sponsor
- Beaver-Visitec International, Inc.
Renal Calculi
External Physical Vibration Lithecbole Versus Traditional Row of Stone After Extracorporeal Shockwave Lithotripsy(ESWL)
The traditional stone row method comprises increasing exercise, drink lots of water, drug row of stone and stone row position. External physical vibration lithecbole(EPVL) is a non-invasive device active row of stone, the…
- Trial name
- NCT02643134
- Testing
- extracorporeal shockwave lithotripsy, External Physical Vibration Lithecbole
- Where
- China
- Volunteers
- 180 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Thyroid Nodules
Characterization of Thyroid Nodules Using Contrast Enhanced Ultrasound
This study will evaluate thyroid nodules using specialized ultrasound imaging methods.
- Trial name
- NCT01225016
- Testing
- Definity contrast agent
- Where
- United States
- Sponsor
- University of Alabama at Birmingham
Kidney Diseases
The Correlation Between Oxidative Stress and Indinated Contrast-Media Nephrotoxicity
Clinically, iodinated contrast-medium (CM) is widely used in angiography and computerized tomography. CM-induced nephropathy (CMIN) is one major complication after application of CM.
- Trial name
- NCT00632892
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Far Eastern Memorial Hospital
Healthy Volunteers
Cardiac Safety Evaluation of P03277
The study is a Phase I, Single center, Randomized, Cross-over Double-blind Placebo-controlled and Open-label Positive-controlled (moxifloxacin) in healthy volunteers.
- Trial name
- NCT03657264
- Testing
- P03277 0.1 mmol/kg, Moxifloxacin 400mg, NaCl 0.9%
- Where
- Belgium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Guerbet
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