Clinical trials: Contrast Agent
Myocardial Infarction, Contrast-induced Nephropathy
Effect of Hydration Guided by Vigileo on the Prevention of CIN After PCI for Patients With AMI
In this study, Vigileo is used to guide hydration adjustment, and SCr is used to estimate renal function. The aim of the study is to investigate the preventive effect of adequate hydration guided by Vigileo on contrast induced…
- Trial name
- NCT04382313
- Testing
- the adequate hydration group guided by Vigileo
- Where
- China
- Volunteers
- 344 people
- Sponsor
- Chinese PLA General Hospital
Urinary Bladder Neoplasms
Virtual Histology of the Bladder Wall for Bladder Cancer Staging
This is a phase Ib study of the safety and performance of a novel intravesical contrast-enhanced Magnetic Resonance Imaging protocol for determination of bladder cancer stage prior to transurethral resection of bladder tumor (21…
- Trial name
- NCT04369560
- Testing
- Magnetic Resonance Imaging, Gadobutrol intravesical administration (4mM), Ferumoxytol intravesical administration (5 mM)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Jodi Maranchie
Breast Cancer, Pancreas Cancer
A First-in-human Clinical Evaluation of SN132D in Patients With Breast and Pancreatic Cancer
This phase I, first-in-human (FIH) study is open-label, non-randomised and non-placebo-controlled. The study is designed to evaluate the safety, tolerability and pharmacokinetics (PK) of a single intravenous dose of SN132D in…
- Trial name
- SPAGOPIX-01 (NCT04080024)
- Testing
- SN132D
- Where
- 2 sites in Sweden
- Volunteers
- 14 people
- Sponsor
- Spago Nanomedical AB
Peripheral Arterial Disease, Chronic Kidney Diseases
Preventing Kidney Injury Using Carbon Dioxide as Contrast Medium in Patients With Peripheral Arterial Disease (PAD) and Chronic Kidney Disease (CKD) Having Arterial Intervention
This research trial will test whether using carbon dioxide as a contrast medium during surgery to open blocked leg arteries can prevent kidney injury.
- Conditions
- Peripheral Arterial Disease, Chronic Kidney Diseases, Acute Kidney Injury
- Trial name
- KID (NCT07891988)
- Testing
- Iodinated contrast medium, CO2 automated injector contrast medium
- Where
- 6 sites in United Kingdom
- Volunteers
- 184 people
- Sponsor
- University of Leicester
Nephropathy
Evaluating the Protective Effect of Pentoxifylline on Contrast Induced Nephropathy
Contrast induced nephropathy (CIN) is of great concern when using contrast media in the new era of medicine. CIN is defined as 25-50% relative increase, 0.5-1 absolute increase in serum creatinin value or 25% fall in GFR.
- Trial name
- NCT01469624
- Testing
- Pentoxifylline
- Where
- Iran
- Volunteers
- healthy volunteers welcome
- Sponsor
- Shiraz University of Medical Sciences
Brain Injuries, Cerebrovascular Disorders
Measuring Blood Flow Characteristics Using Dynamic Contrast Enhanced Magnetic Resonance Imaging
Dynamic contrast-enhanced (DCE) MRI gives quantitative and semi-quantitative information about the integrity of the vascular system and can be used to quantify blood-brain barrier (BBB) integrity.
- Trial name
- NCT02702635
- Testing
- DCE MRI of the brain
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Contrast Enhanced X-ray Based Examination
A Study, Called UV Population, to Learn More About the Safety of the Study Drug Ultravist, Which is Given to Get Clearer X-ray Pictures, in People of Different Sexes, Races, and From Different Countries/Regions
This is an observational study in which patient data from the past of people who received Ultravist prior to an X-ray based scan are studied.
- Trial name
- NCT05428397
- Testing
- Iopromide (Ultravist, BAY86-4877)
- Where
- Germany
- Volunteers
- 152,233 people
- Sponsor
- Bayer
Breast Cancer Screening
CESM ABMR Breast Cancer Screening Trial
This is a single institution, prospective screening trial of women at high risk for developing breast cancer, enriched with women with suspicious lesions on breast MRI which have been recommended for biopsy.
- Trial name
- NCT03517813
- Testing
- Contrast-enhanced Spectral Mammography (CESM)
- Where
- United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- University of Washington
Contrast Induced Nephropathy
Statins for Prevention of Contrast Induced Nephropathy
In this randomized study the investigators wish to explore the role of pre-procedural statin therapy for the prevention of contrast induced nephropathy in patients with moderate-to-severe renal dysfunction, submitted to elective…
- Trial name
- NCT00770796
- Testing
- Atorvastatin
- Volunteers
- 304 people
- Sponsor
- Ospedale Misericordia e Dolce
ARDS (Acute Respiratory Distress Syndrome)
Comparison of 5% Nacl and 10% NaHCO3 As Contrast Agents for Lung Perfusion with EIT
Electrical impedance tomography (EIT) has enabled the bedside monitoring of lung perfusion measurement through the indicator-based contrast method.
- Trial name
- NCT06868810
- Testing
- Injection of hypertonic saline, Injection of 5% NaHCO3
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Peking Union Medical College Hospital
Healthy, Coronary Artery Disease
Dose Finding Study of PB127 Ultrasound Contrast Agent in Healthy Volunteers and Patients With Coronary Artery Disease
The purpose of this study is to determine the dose of PB127 for detection and/or exclusion of coronary artery disease when used with cardiac ultrasound. This study also evaluates the safety of PB127.
- Trial name
- NCT00584818
- Testing
- PB127 for Injectable Suspension
- Where
- 16 sites in United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Point Biomedical
Portal Hypertension
Multimodal Ultrasound and Portal Hypertension
According to international guidelines, Hepatic Venous Pressure Gradient is the gold standard technique for portal hypertension measurement, but it is invasive and poorly available.
- Trial name
- NCT05789641
- Where
- Italy
- Volunteers
- 73 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Osteomyelitis
Ferumoxytol-enhanced Imaging of Osteomyelitis
Diabetic foot infections contribute to 75,000 hospitalizations in the US each year. There is a lifetime incidence of 15-25% of foot infections in diabetics.
- Trial name
- NCT05959590
- Testing
- Ferumoxides 11.2Mg Solution for Injection
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of New Mexico
Healthy
Omnipaque Versus Gastroview as Oral Contrast for Abdominal and Pelvic CT
Patients who are scheduled by their health care provider for routine computed tomography (CT) scan will be asked to participate in this study.
- Trial name
- NCT00478556
- Testing
- Omnipaque, Gastroview
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Ovarian Cancer
MRI in Staging Ovarian Cancer Using MRI Contrast Agent
Can MRI be used to stage ovarian cancer?
- Trial name
- NCT00463996
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Chronic Kidney Diseases
A Study to Explore the Renal Safety of Visipaque Injection 320 mgI/mL in Patients With Chronic Kidney Disease
This parallel-group, randomized, placebo-controlled study will examine the incidence and severity of acute kidney injury (AKI) in patients with chronic kidney disease (CKD) stage III/IV following an i.v.
- Trial name
- NCT03119662
- Testing
- Visipaque
- Where
- 29 sites in United States, Belgium and 4 more
- Volunteers
- 4 people
- Sponsor
- GE Healthcare
Magnetic Resonance Imaging, Hepatocellular Carcinoma
Improving Hepatocellular Carcinoma Screening
This is a monocentric, single blind, interventional, single arm study. It is designed to compare the rates of detection of hepatocellular carcinoma (HCC) by ultrasound (US) used in clinical routine vs.
- Conditions
- Magnetic Resonance Imaging, Hepatocellular Carcinoma, Screening, Contrast-enhanced US
- Trial name
- AMRIK (NCT05828446)
- Testing
- MRI
- Where
- Switzerland
- Volunteers
- 330 people
- Sponsor
- Naik Vietti Violi
Pulmonary Disease
Chest CT Using Low-concentration Iodine Contrast Media
This study aims to evaluate the quality of images when low-concentration iodine contrast agents is used in chest CT with low tube voltage and if they can be used in routine imaging.
- Trial name
- NCT05967117
- Testing
- Iohexol (320mgI/mL) with 120kVp, Iohexol (320mgI/mL) with 100kVp, Iohexol (270mgI/mL) with 100kVp
- Where
- 6 sites in South Korea
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Jung Im Jung
Carotid Artery Stenosis, Atherosclerosis
Contrast-enhanced Ultrasound (CE-US) and Magnetic Resonance Imaging (MRI): Evaluating Plaque Neovascularisation
The first goal of this study is to investigate whether CE-US is able to accurately identify and quantify neovascularisation in carotid artery plaques.
- Trial name
- NCT00677963
- Testing
- sulphur hexafluoride, gadopentate dimeglumine
- Where
- Netherlands
- Volunteers
- 18 people
- Sponsor
- Maastricht University Medical Center
Chronic Hepatitis, Liver Cirrhosis
Hepatocyte-specific Versus Extracellular Contrast Agents for Liver MRI: Prospective, Intra-individual Comparison of Diagnostic Performance for Hepatocellular Carcinoma
Adult patients with chronic hepatitis B and cirrhosis of any etiology who are found to have suspected liver cancer are potentially eligible for the study.
- Trial name
- NCT03892681
- Testing
- hepatocyte-specific contrast agent, extracellular contrast agent
- Where
- South Korea
- Volunteers
- 129 people
- Sponsor
- Yonsei University
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