Clinical trials: Contrast Agent
Renal Transplantation
CE-US in Renal Transplantation
Acute allograft dysfunction is often observed in the first weeks after kidney transplantation. Renal biopsy is universally considered the gold standard procedure for differential diagnosis of acute allograft dysfunction secondary…
- Trial name
- NCT01815320
- Testing
- Contrast-enhanced ultrasound (CE-US), SonoVue
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Ileus; Mechanical, Contrast-induced Nephropathy
Investigation of Relationship Between Contrast Nephropathy and Caval Index Measurement in Patients With Ileus in ED
In this study, the investigators aimed to evaluate the incidence of vena cava inferior diamater on ultrasound guidance of intravascular volume before diagnosis of contrast enhanced CT for diagnostic purposes in ileus patients and…
- Trial name
- NCT03261518
- Testing
- inferior vena cava ultrasound
- Volunteers
- 250 people
- Sponsor
- Derince Training and Research Hospital
Transcatheter Aortic Valve Replacement
CT TAVR Abdomen Study
A standard polyenergetic CT (computed tomography) procedure utilizes 100 ml of iodinated contrast. A recent world-wide shortage of iodine based intravenous contrast has highlighted the need to search for alternative methods or…
- Trial name
- CT TAVR (NCT05758701)
- Testing
- Iodinated Contrast Agent (Omnipaque), Dual Energy CT
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Breast Cancer, Microcalcification
Imaging Quality and Potential Clinical Relevance of Phase Contrast Mammography In-vivo: a Single-center, Prospective Study
Conventional mammography, breast sonography and breast MRI have specific weaknesses. In particular, mammography has a low sensitivity for the detection of mammary carcinoma in patients with a dense breast.
- Conditions
- Breast Cancer, Microcalcification, Image
- Trial name
- NCT06489665
- Testing
- Experimental Intervention
- Where
- 2 sites in Switzerland
- Volunteers
- 350 people
- Sponsor
- University of Zurich
Stenosis, Carotid, Stroke
Deoxyhemoglobin Concentration Changes and Cerebral Perfusion Imaging
To investigate a new method to rapidly modulate pulmonary venous hemoglobin oxygen saturation to enable the use of deoxyhemoglobin concentration in arterial blood as an intra-arterial MRI contrast agent for cerebral tissue…
- Conditions
- Stenosis, Carotid, Stroke, Neurovascular Disorder
- Trial name
- NCT04537611
- Testing
- dHb contrast and gadolinium contrast imaging
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University Health Network, Toronto
Vesico-Ureteral Reflux
Clinical Applications of Contrast-Enhanced Ultrasonography in Pediatric Population - Intravesicle Administration
In children, specifically the intravesicle administration to study vesicoureteral reflux in children already catheterized and scheduled for voiding cystourethrogram (VCUG).
- Trial name
- NCT02986477
- Testing
- Contrast Ultrasound
- Sponsor
- Johns Hopkins University
Intracranial Arterial Aneurysm
Analysis Of Intracranial Artery Lesions Using 2-D/3D Phase Contrast MR
Using phase contrast MR Angiography with NOVA® Software, this study intends to identify,evaluate and map intracranial aneurysm development as well as develope a predicator for future morphological changes of aneurysms and…
- Trial name
- NCT00710281
- Testing
- Additional scan time on standard MR angiography
- Where
- United States
- Sponsor
- Lahey Clinic
Cardiovascular Abnormalities
Magnevist® Injection Enhanced MRA Compared to Non Contrast MRA for the Detection of Structural Abnormalities of the Aortic Arch and Cerebral Branches
The purpose of this study is to look at the safety (what are the side effects) and efficacy (how well does it work) of Magnevist (the study drug) used for MRI of the aortic arch and cerebral branches.
- Trial name
- NCT00310609
- Testing
- Gadopentetate dimeglumine (Magnevist)
- Volunteers
- 123 people
- Sponsor
- Bayer
Carcinoma, Hepatocellular
DCE-MRI for Assessment of Response to TACE of HCC
This study is conducted to evaluate dynamic contrast-enhanced MRI to quantify the efficacy of trans-arterial chemoembolization by comparing imaging results before and after treatment for at least one hepatic tumor and to look at…
- Trial name
- DCE-MRI (NCT02878109)
- Testing
- Post-treatment phase group, Pre-treatment phase group
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Renal Tumors
Development of AI Model for Renal Tumor Diagnosis Using CT and Lab Tests
This multi-center retrospective study aims to develop a multimodal artificial intelligence diagnostic model using preoperative contrast-enhanced CT images and routine laboratory parameters from patients with renal tumors.
- Trial name
- NCT06761742
- Where
- China
- Volunteers
- 1,922 people
- Sponsor
- RenJi Hospital
Atherosclerosis
Comparison of Magnetic Resonance Angiography and Standard Angiography in Diagnosing Atherosclerosis
This study will evaluate ways to improve magnetic resonance angiography (MRA) for diagnosing atherosclerosis (hardening and narrowing of the arteries).
- Trial name
- NCT00001946
- Testing
- Magnetic resonance angiography
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Limbal Dermoid
Visual Quality and Contrast Sensitivity Function for Limbal Dermoid Children After Corneal Transplantation
This study is to inquiry the contrast sensitivity function in the 50 eyes of limbal dermoid children with keratoplasty with quick contrast sensitivity function (quick CSF) test, as well asa to analyze its relationship between…
- Trial name
- NCT03447041
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Alzheimer Disease
Association Between Cerebral Arterial Vascular Flow and Sleep Apnea in Neurodegenerative Alterations
Obstructive sleep apnea syndrome (OSAS) is a sleep-disordered breathing characterized by the occurrence of repeated upper airway obstructions leading to airflow reduction (hypopnea) or cessation (apnea).
- Trial name
- VAAPS (NCT02578303)
- Testing
- Vascular flow measurement by PC-MRI
- Where
- France
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Central Hospital Saint Quentin
Cataract Extraction
Surgical Outcomes After Routine Cataract Extraction & Implantation of a Conventional or Spheric Intraocular Lens
To determine quality of vision post cataract extraction and intraocular lens (IOL) implantation of 2 different acrylic intraocular lenses: Acrysof® Single-Piece IOL and Acrysof® WF, through evaluation of contrast sensitivity…
- Trial name
- NCT00366496
- Testing
- Acrysof single piece (SA60AT), Acrysof IQ (SN60WF)
- Volunteers
- 30 people
- Sponsor
- Medical University of South Carolina
Primary Hepatocellular Carcinoma
Comparison of Liver and Renal Function After Transarterial Chemoembolization for Primary Hepatocellular Carcinoma With Iso-osmolar Contrast Media and Low Osmolar Contrast Media
Primary Hepatocellular Carcinoma (PHC) is one of the most common malignant tumors in the world. In men is the fifth most frequently diagnosed cancer worldwide but the second most frequent cause of cancer death.
- Trial name
- NCT01563484
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Li Chen
Breast Cancer
Efficacy and Safety of Gadobutrol 1.0 Molar (Gadovist) for Breast Magnetic Resonance Imaging (MRI)
The purpose of this study is to look at the efficacy (how does it work) and safety of gadobutrol when used for obtaining MR images of both breasts.Women with a recent diagnosis of breast cancer by mammogram (X-ray examination of…
- Trial name
- GEMMA 2 (NCT01104584)
- Testing
- Gadobutrol (Gadavist, Gadovist, BAY86-4875)
- Where
- 48 sites in United States, Argentina and 7 more
- Volunteers
- 460 people
- Sponsor
- Bayer
Pancreatic Adenocarcinoma
Contrast-harmonic Endoscopic Ultrasound (CH-EUS) for the Diagnosis of Pancreatic Adenocarcinoma
Ductal adenocarcinoma is the most frequent pancreatic solid lesion and the most common tumor of the pancreas. Given its poor prognosis and the major therapeutic consequences, the discrimination between PA and other pancreatic…
- Trial name
- NCT01765036
- Testing
- SonoVue®
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Société Française d'Endoscopie Digestive
Bipolar Depression
Neural and Visual Responses to Light in Bipolar Disorder: A Novel Putative Biomarker
Objective. Bipolar Disorders (BD) are a major public health problem. The investigators still lack knowledge of the mechanisms which contribute to BD.
- Trial name
- LightEyeBD (NCT02048995)
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Cervical Carcinoma, Malignant Female Reproductive System Neoplasm
Gynecological Sentinel Lymph Nodes CEUS
This clinical trial compares the use of ultrasound for the detection of sentinel lymph nodes (SLNs) to the standard of care (which varies depending on cancer treatment).
- Conditions
- Cervical Carcinoma, Malignant Female Reproductive System Neoplasm, Vaginal Carcinoma, Vulvar Carcinoma
- Trial name
- NCT05105087
- Testing
- Perflubutane Microbubble, Contrast-Enhanced Ultrasound
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Thomas Jefferson University
Pain
Contrast and Anesthetic Level With Lumbar Erector Spinae Plan (ESP) Block
As per usual care for spine surgery, participants will have their back cleaned with alcohol and a needle will be placed using ultrasound for the ESP block.
- Trial name
- NCT07174440
- Testing
- Ropivacaine (Epidural analgesia), Dexmedetomidine, Iohexol
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University Hospitals Cleveland Medical Center
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