Clinical trials: Contrast Agent
Contrast-induced Nephropathy
Comparison of Captisol-Enabled™ Iohexol and Omnipaque™ in Patients With Impaired Renal Function Undergoing Coronary Angiography
Randomized parallel group study comparing the renal safety of Captisol-Enabled™ Iohexol (CE-Iohexol) Injection and Omnipaque™ (Iohexol) Injection in patients with impaired renal function undergoing coronary angiography.
- Trial name
- NCT04627831
- Testing
- CE-Iohexol, Iohexol
- Sponsor
- Ligand Pharmaceuticals
Visual Acuity
Visual Outcomes of a Segmental Refractive Multifocal Intraocular Lens
To evaluate visual outcomes of a segmental refractive multifocal intraocular lens (IOL) after cataract surgery.
- Trial name
- NCT03452969
- Testing
- Implantation of multifocal intraocular lens
- Where
- Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Clinic Frankfurt
Healthy, Physiology
Assessment of the Changes in Cortical and Medullary Renal Blood Flow During Exercise in Healthy Subjects Using Contrast Enhanced Ultrasound
Renal parenchymal blood flow can be divided in cortical and medullary blood flow. Changes and factors affecting renal medullary blood flow have not been studied in detail previously as investigators/doctors did not have tools to…
- Trial name
- NCT02672722
- Testing
- Definity, Exercise, Kidney Ultrasound
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Carotid Plaque Imaging
Contrast Enhanced SWI for Carotid Plaque Imaging
This study aims to compare image-based characteristics of carotid walls between symptomatic side and the opposite side. The design of this study is phase IV, prospective observational study.
- Trial name
- NCT02749916
- Testing
- Methods of carotid wall imaging
- Where
- 2 sites in South Korea
- Volunteers
- 25 people
- Sponsor
- Hyun Seok Choi, M.D.
Contrast Medium-induced Nephropathy
Prevention of Contrast Renal Injury With Different Hydration Strategies
Using a randomized controlled trial design, two hydration protocols for the prevention of contrast medium-induced nephropathy will be tested.
- Trial name
- POSEIDON (NCT01218828)
- Testing
- LVEDP -Based hydration strategy, Standard hydration
- Where
- United States
- Volunteers
- 396 people
- Sponsor
- Kaiser Permanente
Unspecified Disorder of Stomach and Duodenum
A Study to Evaluate the Safety and Efficacy of Oral Contrast Agent for Sonography
The goal of this clinical trial is to verify the safety and efficacy of Oral Contrast Agent for Sonography produced by Shandong Baiduo Medical Instruments Co., LTD.
- Trial name
- NCT05676164
- Testing
- KANG XIAN, TIAN XIA
- Where
- China
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Shandong Branden Med.Device Co.,Ltd
Contrast Sensitivity
Contrast Sensitivity Assessment in Pediatric Cataract Surgery With IOL Implantation
The study evaluates contrast sensitivity in older children following surgery for lamellar and posterior subcapsular cataracts. Often, pediatric surgeons tend to delay surgery in these children who present beyond the amblyogenic…
- Trial name
- NCT01901744
- Testing
- Cataract Surgery
- Where
- India
- Volunteers
- 25 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Acute Ischemic Stroke
Dynamic Contrast-enhanced Ultrasound Imaging for Cerebral Perfusion Measurement in Acute Ischemic Stroke
Stroke, a personal, familial, and social disaster, is the first cause of acquired disability, the second cause of dementia, and the third cause of death worldwide. Its associated socio-economic costs are astronomic.
- Trial name
- NCT02415972
- Testing
- Ultrasound perfusion imaging
- Where
- Switzerland
- Volunteers
- 33 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Contrast Induced Nephropathy
Sodium Bicarbonate in Preventing Contrast Induced Nephropathy
We plan to conduct an open-label, randomized, stratified, parallel-group study to compare normal saline infusion to sodium bicarbonate infusion.
- Trial name
- SIPCIN (NCT00531765)
- Testing
- sodium bicarbonate infusion
- Where
- Saudi Arabia
- Volunteers
- 220 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Contrast Induced Acute Kidney Injury
Monitoring Renal Blood Flow With Contrast Enhanced Ultrasound During Coronary Angiogram
Contrast induced nephropathy (CN) is a common cause of acute kidney injury and is associated with increased morbidity and mortality and healthcare cost.
- Trial name
- NCT01544036
- Testing
- perflutren
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of Virginia
Aging Problems
Vascular Aging and Microcirculation: Physiological Aspects of Vascular Aging in the Elderly Population (VAMP-Aging)
Rising life expectancy worldwide challenges public health due to increased cardiovascular disease linked to vascular aging, where microvascular dysfunction serves as an early indicator of system-wide inflammation, or…
- Trial name
- VAMP-Aging (NCT07563725)
- Testing
- Laser Speckle Contrast Imaging, Handgrip Dynamometry (Muscle Strength), Sit-to-Stand Test (5-Times Sit-to-Stand - 5STS)
- Where
- Brazil
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Ultrasound, Breast Cancer
Added Value of Contrast-enhanced Ultrasound for BI RADS 4A Nodules
The aim of this study was to investigate the added value of contrast-enhanced ultrasound (CEUS) for differentiating low risk patients with breast nodules categorized as 4A using the Breast Imaging Reporting and Data System…
- Conditions
- Ultrasound, Breast Cancer, Pathology
- Trial name
- BIRADS (NCT04929132)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pulmonary Thromboembolisms, Pulmonary Embolism
Non-Contrast 4DCT to Detect Pulmonary Thromboembolic Events
Deep vein thrombosis (DVT) occurs when a blood clot forms in a deep vein, typically in the lower extremities. Pulmonary embolism (PE) occurs when a DVT clot (or fragment) breaks free and travels through the heart to the pulmonary…
- Trial name
- NCT03183063
- Testing
- 4DCT and SPECT/CT, 4DCT with BiPAP and SPECT/CT, 4DCT with CTA in suspected PE
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Thomas Guerrero
Chronic Kidney Diseases, Chronic Kidney Disease 5D
The Discrepancy in Radiologists' Practice of Intravenous Contrast Imaging Studies Among Chronic Kidney Disease Patients
There is a discrepancy between protocols used for intravenous imaging for chronic kidney disease including hemodialysis patients among different hospitals and even, among radiologists same selves.
- Trial name
- NCT05729126
- Testing
- Questionnare
- Where
- Egypt
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Benha University
Coronary Artery Disease
Contrast-Enhanced Whole-Heart Coronary Magnetic Resonance Angiography at 3.0-T: A Multicenter Trial
The multicenter study evaluates the diagnostic performance of 3.0 T contrast-enhanced whole-heart coronary MRA in patients with suspected coronary artery disease.
- Trial name
- NCT01024478
- Where
- China
- Volunteers
- 272 people
- Sponsor
- Capital Medical University
Myopia
Impact of Positive & Negative Lens-Induced Defocus on Contrast-Sensitivity in Myopic & Non-Myopic Adults
examines the influence of lens-induced defocus on contrast sensitivity-a crucial aspect of visual performance.Each participant experiences both positive and negative defocus through different lenses, with measurements taken for…
- Trial name
- NCT06753032
- Testing
- Positive Lens-Induced Defocus Using Spectacle Lenses (+2.00 D) for Myopic Participants, Negative Lens-Induced Defocus Using Spectacle Lenses (-2.00 D) for Myopic Participants, Positive Lens-Induced Defocus Using Spectacle Lenses (+2.00 D) for Non-Myopic Participants
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Superior University
Vision, Low, Mobility Limitation
Evaluating Stairway Designs for Individuals With Vision Impairment
The goal of this study is to learn if contrast frequency on step tread-edges influences foot clearance measures, a marker of fall risk, in older adults with and without visual impairments.
- Trial name
- NCT07337317
- Testing
- Frequency of contrast marking on stair steps
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- The University of Alabama in Huntsville
Atrial Fibrillation
Efficacy of Optison Echo Contrast to Detect Thrombus in Left Atrial Appendage
The investigators intend to determine if using Optison echocardiography contrast increases sensitivity and specificity of detecting left atrial appendage thrombus in transesophageal echocardiography studies as opposed to standard…
- Trial name
- DOLOP (NCT01721447)
- Testing
- Optison echocardiography contrast agent
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Utah
Transplantation, Kidney
The Effect of Erythropoietin Usage in Renal Function After Kidney Transplantation, in Early Phase, in Contrast to Placebo Group
The study hypothesis is that erythropoietin usage after kidney transplantation, in early phase, can improve the outcome for patients and their graft increasing patient and graft survival.
- Trial name
- NCT00617474
- Testing
- Erythropoietin
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Labbafinejhad Hospital
Cerebral Arterial Diseases
Carotid and Vertebral Magnetic Resonance Angiography (MRA) Study Comparing Dotarem and Time Of Flight (TOF)
The study will evaluate the efficacy and safety of Dotarem enhanced MRA in patients suffering from carotid or vertebral arterial disease.
- Trial name
- NCT01010932
- Testing
- Dotarem, TOF MRA
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- Guerbet
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