Clinical trials: Contrast Agent
Diffuse Large B-cell Lymphoma
The Study of Pegylated Liposomal Doxorubicin Contrast Epirubicin for the Treatment of Diffuse Large B-cell Lymphoma
270 untreated patients, age between 18 and 65 years , with diffuse large B-cell lymphoma (B-DLCL) were treated with a pegylated liposomal doxorubicin (PL-doxorubicin) modified CHOP-rituximab regimen.
- Trial name
- NCT03022123
- Testing
- PL-doxorubicin and epirubicin
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Hebei Medical University Fourth Hospital
Heart Transplant Patients
Scanner and Transplant Heart Patients Protocol
Coronary vasculopathy remains the leading cause of decreased survival after the first year post-transplantation. It is mainly asymptomatic because of the denervation of the heart transplant.
- Trial name
- NCT01122810
- Testing
- Coronary scanner
- Where
- France
- Volunteers
- 102 people
- Sponsor
- French Cardiology Society
Kidney Failure, Chronic
A Safety Comparison of Iopromide and Iodixanol in Renal Impaired Patients
The investigators intend to find out which contrast agent has less kidney toxicity in renal impaired patients undergoing cardiac angiography or percutaneous coronary intervention (PCI).
- Trial name
- DIRECT (NCT00926562)
- Testing
- Iopromide (Ultravist), Iodixanol (Visipaque)
- Where
- 19 sites in China
- Volunteers
- 592 people
- Sponsor
- Chinese PLA General Hospital
Eye Cancer
MRI in Diagnosing Solid Tumors of the Eye and Orbit
This study is being done due to a new imaging method that may help others in the future to improve evaluation of diseases in the eye and eye socket and to help make a decision concerning best treatment of the disease.
- Trial name
- NCT01653080
- Testing
- dynamic contrast-enhanced MRI
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Cincinnati
Ophthalmoplegia
Prevalence of Contrast Enhancement of the Oculomotor Nerve on 3D PD T1 MRI Sequence in Patients With Ophthalmoplegia
Oculomotor nerve (third cranial nerve or "III") palsy is a relatively frequent cause of consultation in ophthalmology. It may reveal a life-threatening pathology such as aneurysm rupture, pituitary apoplexy, and therefore need…
- Trial name
- 3D-III (NCT03269682)
- Testing
- 3D PD T1 MRI sequence
- Where
- France
- Volunteers
- 134 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Athletic Performance
Priming Using Contrast Training Exercise
This study investigated the effects of a morning complex-contrast training session on afternoon sport-specific and physical performance in competitive judokas.
- Trial name
- NCT07754669
- Testing
- Morning Complex-Contrast Training, Time-Matched Walking Control Condition
- Where
- Poland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Patients With Intraosseous Vascular Access Requiring Computed Tomography (CT) Exam
Observational Study of CT Dye Administration Through the Intraosseous Vascular Access Route
An observational study to determine the safety and effectiveness of Intraosseous (IO) vascular access for delivery of contrast dye for Computed Tomography (CT) examination.
- Trial name
- NCT01531686
- Testing
- Intraosseous delivery of CT contrast dye
- Where
- 4 sites in United States
- Volunteers
- 8 people
- Sponsor
- Vidacare Corporation
Dual Sensory Impairment of Vision and Hearing
Gaining Insight Into Dual Sensory Loss
The goal of this observational study is to explore difficulties in information access, mobility, communication and fatigue in people with combined vision and hearing impairments.
- Trial name
- DSL (NCT06362213)
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- Amsterdam UMC, location VUmc
Gastrointestinal Subepithelial Tumors
EUS-Elastography and Contrast-Enhanced EUS Diagnostic Accuracy in the Differential Diagnosis of Subepithelial Gastrointestinal Tumors
The differentiation among the Gastrointestinal Subepithelial Tumors (SETs) represents a clinical challenge. Endoscopic Ultrasound (EUS) alone may be ineffective in differentiating SETs subtypes, and tissue sampling of these…
- Trial name
- SUNNYDAY (NCT04695262)
- Testing
- EUS-FNB
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Istituto Clinico Humanitas
Multiple Sclerosis
Vision Assessment With the Quick Contrast Sensitivity Function (qCSF) Method in Healthy Controls and MS
Victor2 is an observational cohort study over two years and is designed to investigate longitudinal changes of visual impairment in multiple sclerosis (MS).
- Trial name
- VICTOR2 (NCT03703180)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Breast Cancer, Contrast Enhanced Ultrasound
Pilot Study to Evaluate if Contrast Enhanced Ultrasound (CEUS) Can Predict Treatment Response in Triple Negative Breast Cancer (TNBC) Patients Receiving Combined Chemotherapy and Immune Checkpoint Inhibitors (ICI).
To find out if contrast enhanced ultrasound (CEUS) can be used to determine if patients receiving combined ICI therapy for triple negative breast cancer (TNBC) are responding to treatment earlier than standard of care MR or CT.
- Trial name
- NCT05957042
- Testing
- Lumason
- Where
- United States
- Sponsor
- Milton S. Hershey Medical Center
Contrast Media Induced Nephropathy
Nephroprotective Effects of Carnitine and (PDE5) Inhibitor Agent Against Contrast Media-induced Nephropathy (CMN)
CIAKI is a common iatrogenic. Up to date the suggested treatments for CIAKI are partially effective and have not been approved by the Food and Drug Administration yet.
- Trial name
- NCT01564303
- Testing
- Acetylcysteine, Phosphodiesterase type 5 inhibitor ,Carnitine
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- The Nazareth Hospital
Exertional Heat Illness, Hydration Status
Comparing Risk of Heat Illness Based on Peak Core Temps During Preseason Football Camp Across 3 Different Age Levels
To collect field data in professional, collegiate, and high school football players to determine how they respond physiologically to the rigors of preseason training environment.
- Trial name
- NCT01954537
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Liver Neoplasms
A Trial on Contrast-enhanced Ultrasound Versus Conventional Ultrasound Guided Biopsy of Liver Neoplasms
The purpose of this study is to estimate the clinical value of contrast-enhanced ultrasound in percutaneous biopsy for liver occupied lesion.
- Trial name
- NCT02413437
- Testing
- CEUS guided biopsy, US guided biopsy, Ultrasound
- Where
- China
- Volunteers
- 2,088 people
- Sponsor
- Peking University Cancer Hospital & Institute
HCC
"Double Low-Dose" DECT for HCC Imaging
Hypothesis: double low-dose protocol provide better lesion conspicuity than standard protocol CT in patients at high-risk of HCC.
- Trial name
- NCT03045445
- Testing
- Double Low-Dose protocol CT, Standard protocol CT
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Seoul National University Hospital
Angiography, Multidetector Computed Tomography
A Non-interventional Study to Observe the Computed Tomographic Angiography Image Quality With Different Contrast Media Injection Protocols Under Different Computed Tomography Machines Parameters Setting
The objective of this study is to evaluate the image quality for different iodine delivery rates at different low voltage scanning protocols (80 or 100 kV ) under the modern advanced Multi-Detector Computed Tomography (MDCT)…
- Trial name
- RIGHT (NCT02840903)
- Testing
- Iopromide (Ultravist, BAY86-4877)
- Where
- China
- Volunteers
- 1,214 people
- Sponsor
- Bayer
Lung Neoplasms, Emphysema
Computed Tomography Assessment of Regional Ventilation (CURVE)
This study uses CT scans to assess airflow in the lung, the scan is quick, cheap and painless. The information from the scan may help doctors tell which patients are suitable to have surgery to cure early stage lung cancer.
- Conditions
- Lung Neoplasms, Emphysema, Lung Diseases, Interstitial, Pulmonary Disease, Chronic Obstructive
- Trial name
- CURVE (NCT02879773)
- Testing
- CTPVe
- Where
- United Kingdom
- Volunteers
- 131 people
- Sponsor
- Heart of England NHS Trust
Peripheral Artery Disease
Contrast Ultrasound Perfusion Imaging in PAD With Sonazoid
The measurement of limb skeletal muscle perfusion and perfusion reserve during exercise is an approach that can assess the total impact of the complex pathophysiologic processes in patients with limb ischemia, particularly in…
- Trial name
- NCT02398266
- Testing
- Contrast ultrasound of leg muscle with Sonazoid (Contrast ultrasound microvascular perfusion imaging)
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Ischemic Stroke
The Norwegian Sonothrombolysis in Acute Stroke Study Part 2
BACKGROUND: Thrombolytic drugs may dissolve blood vessel clots in acute ischemic stroke. The overall benefit of intravenous thrombolysis is substantial, but up to 2/3 of patients with large clots may not achieve re-opening of the…
- Trial name
- NOR-SASS 2 (NCT01949961)
- Testing
- Ultrasound
- Where
- Norway
- Volunteers
- 59 people
- Sponsor
- Haukeland University Hospital
Aortic Stenosis
Non-contrast 3-dimensional Cardiac Magnetic Resonance Imaging
Non-contrast enhanced cardiac MRI using 3D whole heart acquisition protocol is non-inferior to contrast enhanced CT in the assessment of aortic annulus complex for pre-TAVR imaging.
- Trial name
- NCT04496297
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- Baylor Research Institute
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