Clinical trials: Contrast Agent
Calculi, Stenosis of Bile Duct
EUS Prior to ERCP in the Positive Setting of Positive Intraoperative Cholangiogram (IOC) During Cholecystectomy
Performing an EUS prior to ERCP in the setting of a positive intraoperative cholangiogram will identify and risk stratify patients for the presence of CBD stones and strictures.
- Trial name
- NCT01525355
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Breast Cancer
Comparison of CE-DBT and MRI in Patients With Known Breast Lesions
The purpose of this pilot study is to compare radiologist confidence level in evaluating patients with known breast lesions between contrast enhanced digital breast tomosynthesis (CE- DBT) and contrast enhanced dynamic magnetic…
- Trial name
- NCT05754749
- Testing
- Iohexol 350 Mg/mL Injectable Solution
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
DCIS, Breast Carcinoma in Situ
The Added Value of Contrast Enhanced Mammography to Standard Mammography in Assessing the Extent of DCIS
The study hypothesis is that the rate of inadequate surgical margins after conservative breast surgery for DICS and the rate of reoperation (re-excision or/and mastectomy) is lower in the group of patients who underwent standard…
- Conditions
- DCIS, Breast Carcinoma in Situ, Calcification
- Trial name
- CEMinDCIS (NCT06217458)
- Testing
- Contrast Enhanced Mammography
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- Clinical Hospital Center Rijeka
Pulmonary Hypertension, Elevated Mean Pulmonary Arterial Pressure
Non-contrast Enhanced Cardiac Magnetic Resonance Imaging in the Diagnosis and Classification of Pulmonary Hypertension
Pulmonary hypertension (PH) is a life-threatening cardiovascular disease characterized by pathological elevation of mean pulmonary arterial pressure (mPAP) >/= 25 mmHg at rest.
- Conditions
- Pulmonary Hypertension, Elevated Mean Pulmonary Arterial Pressure, Normal Mean Pulmonary Arterial Pressure
- Trial name
- CMR-PH (NCT01725763)
- Testing
- Cardiac MRI
- Where
- Austria
- Volunteers
- 150 people
- Sponsor
- Medical University of Graz
Myocardial Perfusion Imaging
Real-Time Myocardial Perfusion Echocardiography in the ICU
This study is being done to find out if and how much the use of RTMPE improves a provider's confidence in the diagnosis they assign.
- Trial name
- NCT03173716
- Testing
- Definity
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Mayo Clinic
Breast Cancer
Comparison of MRI and CEDM to Evaluate Treatment Response Before Surgery
The purpose of this study is to compare the diagnostic accuracy of breast magnetic resonance imaging (MRI) and contrast enhanced digital mammography (CEDM) in assessing the residual disease extent in patients who have completed…
- Trial name
- NCT03070340
- Testing
- Breast Magnetic Resonance Imaging (MRI), Contrast Enhanced Mammography (CEDM)
- Where
- 5 sites in United States
- Volunteers
- 125 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Non Mass Breast Lesions
Diagnostic Accuracy of Multiparametric Dynamic Contrast Enhanced Magnetic Resonance Imaging in Improving Detection of Ultrasound Non-mass Breast Lesions According to ACR BI-RADS v2025
this study aims To evaluate the diagnostic performance of Ultrasound (US) in correlation with Dynamic Magnetic Resonance Imaging (MRI) for the assessment, characterization, and evaluation of non-mass breast lesions.
- Trial name
- NCT07679308
- Testing
- multiparametric DCE- MRI and US for all patients
- Volunteers
- 60 people
- Sponsor
- Sohag University
Renal Artery Stenosis
A Safety & Efficacy Clinical Study to Evaluate the Narrowing of the Renal Arteries While Using Gadodiamide
Magnetic Resonance Angiography (MRA) is an examination similar to Magnetic Resonance Imaging (MRI) which uses a magnetic field and a contrast medium when needed to visualize blood flow in the arterial vessels throughout the body.
- Trial name
- NCT00209391
- Testing
- Gadodiamide Injection
- Where
- Germany
- Volunteers
- 395 people
- Sponsor
- GE Healthcare
Multiple Sclerosis, Optic Nerve
Single Oral Doses Study of Nerispirdine on Visual Function in Patients With Multiple Sclerosis
The primary objective of the study was to evaluate the effect of Nerispirdine (50 mg or 400 mg) and placebo given orally as a single dose once a week in crossover design on latency of Visual Evoked Potentials (VEP) P100 in optic…
- Conditions
- Multiple Sclerosis, Optic Nerve, Neuritis
- Trial name
- NCT00772525
- Testing
- Nerispirdine
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Sanofi
Nephropathy
Effect of Intravenous Acetadote on Incidence of Contrast Induced Nephropathy
In patients undergoing coronary angiography, the incidence of contrast induced nephropathy(CIN)varies widely and ranges from < 5% in the lowest risk patients, to nearly 50% in the highest risk patients.
- Trial name
- NAC (NCT00939913)
- Testing
- intravenous NAC
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Ochsner Health System
Pulmonary Perfusion, Ventilation-Perfusion Ratio
Non-apnea Electrical Impedance Tomography for Bedside Ventilation-Perfusion Assessment: a Prospective Cross-over Validation Study
Title: Validating the Accuracy of Lung Blood Flow Monitoring Without Breath-Holding Under Spontaneous Breathing Support Purpose: The purpose of this study is to evaluate the accuracy of a new Electrical Impedance Tomography (EIT)…
- Conditions
- Pulmonary Perfusion, Ventilation-Perfusion Ratio, Respiratory Insufficiency, Critical Illness
- Trial name
- NELSB (NCT07489950)
- Testing
- Saline-contrast EIT with a non-apnea algorithm
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Ruijin Hospital
Renal Malignant Tumor
Correlation of Renal Mass Pathologic Grade and Contrast Enhanced Ultrasound (CEUS)
Patients with renal lesions suspicious for renal cell carcinoma (RCC) have a variety of different treatment pathways available to them.
- Trial name
- NCT03821376
- Testing
- Contrast enhanced ultrasound with Lumason
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Indiana University
Coronary Artery Disease
Safety and Effectiveness of Visipaque 320mg-I/ml for Use in Contrast-Enhanced CT Angiography of Arteries of the Heart
CT (computed tomography) angiography (CTA) is an examination similar to a CAT scan that uses x-rays and a contrast medium (also called dye) to visualize blood flow in arteries and veins throughout the body.
- Trial name
- NCT00335335
- Testing
- iodixanol
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- GE Healthcare
Aortic Aneurysm
Patient Tailored Contrast Volume for Preoperative CT Angiography of the Aorta
An in-house calculator was developed to calculate the appropriate contrast dose, rather than standardly administering a 120ml dose.
- Trial name
- NCT05716568
- Testing
- Contrast dose reduction, CT-angiography
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Colorectal Cancer
Trial of Aflibercept Monotherapy With DCE-US in Chemorefractory Metastatic Colorectal Cancer
Various antiangiogenic agents have a modest effect in prolonging overall survival in solid tumours. In colorectal cancer it is clear that there are some patients in whom bevacizumab significantly prolongs survival, but it is not…
- Trial name
- AUSCOR (NCT03264274)
- Testing
- Aflibercept, Dynamic Contrast Enhanced Ultrasound
- Sponsor
- Barts & The London NHS Trust
Breast Cancer
Performance of Contrast-Enhanced Spectral Mammography to Assess Neoadjuvant Chemotherapy Response (CEDM)
This study is designed to investigate the diagnostic accuracy of Contrast Enhanced Spectral Mammography (CEDM) in predicting early neoadjuvant therapy response and pathologic complete response (pCR) compared to mammography.
- Trial name
- NCT04625517
- Testing
- Digital Mammography, Low Osmolar Contrast Material, 300-399 Mg/Ml Iodine Concentration, Per Ml
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Texas Southwestern Medical Center
Renal Failure
Urinary Neutrophil Gelatinase-Associated Lipocalin (uNGAL) in Invasive Cardiology
Diagnosis of acute kidney injury (AKI) relies on a late marker, namely serum creatinine (SCr). New biomarkers are considered for early and sensitive detection of CIN.
- Trial name
- NCT01612117
- Where
- Switzerland
- Volunteers
- 244 people
- Sponsor
- University of Freiburg
Neonatal Post-Hemorrhagic Hydrocephalus
Contrast Enhanced Ultrasound Evaluation of Brain Perfusion in Neonatal Post-Hemorrhagic Hydrocephalus
The aim of the proposed project is therefore to utilize the CEUS technique to assess cerebral perfusion changes before and after ventricular shunting in neonatal cases of PHH.
- Trial name
- NCT03061045
- Testing
- Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Intravenous Powder for Suspension [LUMASON]
- Sponsor
- Johns Hopkins University
Hypertension,Essential
Brain BOLD fMRI in Hypertensive and Normotensive Participants
This study will explore the brainstem activity in response to stress in hypertensive patients and normotensive subjects. In addition, it will evaluate if the response in hypertensive patients can be modulated by blocking the…
- Trial name
- BRAIrdN (NCT03473275)
- Testing
- Cold Pressor test, PinPrick test
- Where
- Switzerland
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
ST Elevation (STEMI) Myocardial Infarction, Contrast Induced Nephropathy (CIN)
Beyond the Mehran Risk Score: Predictive Value of Total Ischemic Time for Contrast-Induced Nephropathy in ST Segment Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention.
Contrast-Induced Nephropathy (CIN) is a serious complication following primary percutaneous coronary intervention (PCI) in patients presenting with acute ST-segment elevation myocardial infarction (STEMI).
- Conditions
- ST Elevation (STEMI) Myocardial Infarction, Contrast Induced Nephropathy (CIN), Acute Kidney Injury
- Trial name
- NCT07826572
- Testing
- Total Ischemic Time Evaluation
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assiut University
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