Clinical trials: Contrast Media
Breast Cancer
Cone Beam Computed Tomography for Breast Imaging
The primary aim of this study is to investigate the use of cone beam computed tomography (CBCT) for breast imaging in the diagnostic setting by providing a compelling body of evidence incorporating both non-contrast and contrast…
- Trial name
- CBCTBI (NCT00972413)
- Testing
- Computed Tomography
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Koning Corporation
Atrial Fibrillation
High-resolution MRI of Atrial Fibrillation Patients Prior to Focal Impulse and Rotor Modulation (FIRM) Ablation
Patients undergoing FIRM guided ablation of atrial fibrillation will undergo high resolution MRI imaging to determine correlation of underlying anatomic fibrotic regions with FIRM targeted sites for ablation.
- Trial name
- NCT03444337
- Testing
- Catheter Ablation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Carcinoma, Renal Cell, Diagnostic Imaging
Deep Learning for Automated Discrimination Between Stage T1-T2 and T3 Renal Cell Carcinoma on Contrast-Enhanced CT
This study aims to develop and validate a contrast-enhanced CT-based deep-learning model for automatic and accurate preoperative discrimination between T1-T2 and T3 renal cell carcinoma.
- Conditions
- Carcinoma, Renal Cell, Diagnostic Imaging, Pathology, Deep Learning
- Trial name
- NCT07166445
- Testing
- None intervention
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Peripheral Artery Disease
Optical Imaging Measurement of Intravascular Solution Efficacy Trial
Iodinated contrast is the current gold standard for infrainguinal angiography imaging in patients without renal insufficiency and has also been used with intravascular Optical Coherence Tomography (iOCT) to improve image quality…
- Trial name
- OPTIMISE (NCT01743872)
- Testing
- Contrast Injection, Dextran Injection, CO2 Injection
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Anxiety, Stress
Assessment of Stress and Anxiety for Patients Undergoing MRI Using, Holy Quran, Music, and Natural Sounds
The aim of the current study is to analyze the effect of listening to Quran or music or natural sounds on anxiety and stress level among patients undergoing MRI.
- Conditions
- Anxiety, Stress, MRI Contrast Media Adverse Reaction
- Trial name
- NCT06348862
- Testing
- Listening to either Quran, Music, and or Natural sound
- Where
- Palestinian Territories
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Al-Quds University
Coronary Artery Disease, Coronary Atheroscleroses
Screening Coronary Artery Disease Using artiFicial intelligencE in Non-contrast Computed Tomography
This project aims to improve direct patient care by reducing the risks of futile exposure to ionizing radiation and iodinated contrast in patients referred for coronary computed tomography angiography
- Trial name
- SAFE-CT (NCT06438393)
- Testing
- CT coronary angiography and non-contrast CT
- Where
- Portugal
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Carotid Artery, External
Feasibility Study of Phase-contrast MRI for Flow in the External Carotid Branches Arteries
The phase-contrast MRI offers the advantage to combine precisely vascular flow measurements data with morphological images. Even if the anatomy of the external carotid artery is well known, data obtained through Phase contrast…
- Trial name
- IRM-de-FLUX (NCT02829190)
- Testing
- Magnetic Resonance Imaging (MRI),
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Emergency
Variation IGFBP7 Markers and TIMP2 Induced by Injection of Contrast Iodized Drug at the Intensive Care Patient
Multicenter, prospective, uncontrolled study to evaluate variations in urinary concentrations of TIMP-2 and PCI IGFBP7 induced injection during a CT scan in intensive care patient.
- Trial name
- ContraCHECK (NCT02881710)
- Testing
- contrast product used to assess biomarkers variations
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Transcatheter Aortic Valve Replacement
CT TAVR Abdomen Study
A standard polyenergetic CT (computed tomography) procedure utilizes 100 ml of iodinated contrast. A recent world-wide shortage of iodine based intravenous contrast has highlighted the need to search for alternative methods or…
- Trial name
- CT TAVR (NCT05758701)
- Testing
- Iodinated Contrast Agent (Omnipaque), Dual Energy CT
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Breast Cancer Diagnosis
Evaluation of Diagnostic Accuracy of Contrast Enhanced Dual Energy Mammography Imaging in Comparison to CE-MRI
Clinical study to evaluate diagnostic accuracy of low dose contrast enhanced dual energy mammography imaging (CEDEM+PRIME) in comparison with CE-MRI The primary objective of this clinical study is to assess diagnostic accuracy in…
- Trial name
- CEDEM (NCT02608281)
- Testing
- CONTRAST ENHANCED DUAL ENERGY (CEDEM)
- Where
- Austria
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Siemens Healthcare QT
Cataract After, Astigmatism
Influence of Residual Astigmatism on Visual Acuity in Patients Undergoing Cataract Surgery With Trifocal Intraocular Lens Implantation
MAIN OBJECTIVE: To assess the influence of residual astigmatism on visual acuity in the different lens foci in patients operated on for cataracts with a trifocal intraocular lens implant.
- Conditions
- Cataract After, Astigmatism, IOL, Visual Acuity
- Trial name
- NCT04387721
- Testing
- Kind of trifocal IOL
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Enrique Ordiñaga-Monreal, OD, MSc
Visual Acuity
Role of Glare and Spectral Filtering on Contrast Sensitivity: A Pilot Study
This will be a split-plot design, randomized, parallel, double-masked feasibility study to evaluate the role of a test lens on contrast sensitivity with and without glare.
- Trial name
- NCT05582304
- Testing
- Test Lens, Control Lens
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
AKI - Acute Kidney Injury
Allopurinol and Trimetazidine as a Preventive of Acute Kidney Injury in PCI Patients
Contrast-associated acute kidney injury (CA-AKI) is a common complication of procedures with intravascular contrast. Generally, CA-AKI is defined as serum creatinine (Scr) ≥ 25 to 50% or Scr rise around 0.3 to 0.5 mg/dl.
- Trial name
- NCT05540184
- Testing
- Trimetazidine 35 mg, Allopurinol 300 MG, Normal saline
- Where
- Egypt
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Contrast-enhanced MRI With Dotarem
Post-marketing Surveillance Study for Evaluation of Dotarem Safety
Guerbet conducted a non-interventional post-marketing surveillance study on its Magnetic Resonance Imaging (MRI) contrast agent Dotarem (gadoteric acid/gadoterate meglumine).
- Trial name
- NCT03048006
- Testing
- MRI with Dotarem
- Volunteers
- 44,456 people, healthy volunteers welcome
- Sponsor
- Guerbet
Lenses, Intraocular
Visual Acuity After Using A New Monofocal Intraocular Lens Compared To Standard Monofocal Lens
This is a prospective comparative interventional clinical study, that took place from January 2021 to November 2021. Twenty patients (20) were enrolled in this study 10 patients in each group.
- Trial name
- NCT05430295
- Testing
- phacoemulsification, monofocal intraocular lens implantation
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Breast Cancer Screening
CESM ABMR Breast Cancer Screening Trial
This is a single institution, prospective screening trial of women at high risk for developing breast cancer, enriched with women with suspicious lesions on breast MRI which have been recommended for biopsy.
- Trial name
- NCT03517813
- Testing
- Contrast-enhanced Spectral Mammography (CESM)
- Where
- United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- University of Washington
Healthy
Renal NCE-MRI in Healthy Volunteers
Non-contrast enhanced (NCE) structural MRI enables to investigate renal anatomy. Additional NCE-MR acquisition modalities (e.g. Diffusion Weighted Imaging (DWI), Blood Oxygenation Level Dependent (BOLD) MRI, Arterial Spin…
- Trial name
- NCT02618460
- Testing
- Non contrast-enhanced magnetic resonance imaging
- Where
- Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
Pulmonary Embolism
Assessment of Contrast Enhancement Boost for the Direct Identification of Pulmonary Emboli in Thoracic CT Angiography
Pulmonary embolism is a common cardiovascular disease and thoracic CT angiography is currently considered the gold standard for its non-invasive diagnosis.
- Trial name
- NCT04654156
- Testing
- Contrast Boost post processing technique
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Brain Vascular Disorders, Coronary Artery Disease
Detection of Ultrasound Contrast Signals in the Cerebral Circulation
To Determine whether transcranial ultrasound can detect the presence of intravenously injected microbubbles used routinely for dobutamine stress echocardiography.
- Trial name
- NCT00579241
- Testing
- Ultrasound on Temporal Bone
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nebraska
Abdominal Diseases
Rapid Abdominal Diagnosis With AI & Radiology
This study aims to develop an AI-assisted diagnostic system for abdominal contrast-enhanced CT images using data from multiple inpatient centers.
- Trial name
- RADAR (NCT07040358)
- Where
- China
- Volunteers
- 2,000,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University