Clinical trials: Contrast Media
Coronary Artery Disease, Coronary Artery Angiography
Vitamin E and N-acetylcysteine for Preventing Contrast-Induced Acute Kidney Injury After Coronary Artery Catheterization
In a double-blinded randomized clinical trial, all patients undergoing coronary artery catheterization who will met our criteria, will be enrolled into three groups to receive either, vitamin e, n-acetylcysteine, or placebo.
- Conditions
- Coronary Artery Disease, Coronary Artery Angiography, Coronary Catheterization, Contrast-induced Nephropathy
- Trial name
- NCT03755700
- Testing
- Vitamin E, N-acetyl cysteine, Normal Saline Flush, 0.9% Injectable Solution
- Where
- Iran
- Volunteers
- 1,000 people
- Sponsor
- Rajaie Cardiovascular Medical and Research Center
Hepatic Disease
Evaluation of the Efficacy of Contrast Enhanced Ultrasound Compared to MRI for Differentiation of Hepatic Lesions
In patients with hepatic lesions, to evaluate the efficacy of contrast enhanced ultrasound compared to MRI in differentiating focal nodular hyperplasia and hepatic adenoma.
- Trial name
- NCT03652636
- Testing
- Sulfur Hexafluoride Microspheres
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Indiana University
Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)
The main purpose of this study is to evaluate the efficacy and safety of lebrikizumab in participants with chronic rhinosinusitis and nasal polyps treated with intranasal corticosteroids. The study will last about 18 months.
- Trial name
- NCT06338995
- Testing
- LY3650150, Standard therapy for INCS
- Where
- 202 sites in United States, Argentina and 18 more
- Volunteers
- 510 people
- Sponsor
- Eli Lilly and Company
Pulmonary Embolism
Strategies to Reduce Contrast Medium in Spectral CT Pulmonary Angiography
The purpose of this study is to assess the effect of three different strategies to inject at reduced volume of contrast medium in Computed Tomography Pulmonary Angiography (CTPA).
- Trial name
- NCT05592444
- Testing
- Low iodine Spectral Detector CT Pulmonary Angiography
- Where
- Norway
- Volunteers
- 330 people
- Sponsor
- University Hospital, Akershus
Multiple Sclerosis
Evaluation of Sloan-Charts for Assessment of Disease Progress in Multiple Sclerosis
Impairment of visual deficits, in particular contrast acuity and contrast impairment are frequent symptoms in MS. However, visual function is not appropriately covered by the standard tools for clinical assessment, namely, the…
- Trial name
- NCT01272596
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Charite University, Berlin, Germany
Acute Aortic Syndrome
Is a Pre-contrast Scan Necesary to Diagnose Acute Aortic Syndrome?
Acute Aortic Syndrome (AAS) is a potentially life-threatening cause of sudden, severe chest pain. There are several possible underlying causes, which cannot be distinguished from one another at the bedside.
- Trial name
- NCT02273245
- Testing
- Thoracic aortogram CT
- Where
- United Kingdom
- Volunteers
- 160 people
- Sponsor
- University Hospital Plymouth NHS Trust
Contrast Induced Acute Kidney Injury
Contrast-inDuced nephRotoxicity as Assessed by the KIdney Load-to-DAmage RElationship
We previously demonstrated that the slope of the relationship plotting individual iodine loads against contrast-induced serum creatinine changes ( the load-to-damage relationship, LDR) characterizes the intrinsic nephrotoxicity…
- Trial name
- DrKILDARE (NCT01908309)
- Testing
- Iobitridol 350, Iodixanol 320
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Azienda Sanitaria Locale 9, Grosseto
Healthy
Open Label, Randomized Study of Low Concentration Ioforminol Injections for Use in Abdominal CECT in Healthy Volunteers
To optimize both the Ioforminol concentration and dosage(s) for CECT of the abdomen. To evaluate the safety and tolerability of low concentration Ioforminol Injections. Study recruits healthy volunteers.
- Trial name
- NCT01672996
- Testing
- Ioforminol 160 mgI/mL, Ioforminol 200 mgI/mL, Iopamidol 300 mgI/mL
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
COPD
Assessment of Lung Perfusion in Patients With Chronic Obstructive Pulmonary Disease Using FD MRI
In the recent years a novel method for functional lung imaging called Fourier decomposition MRI (FD MRI) has been introduced that allows for simultaneous assessment of regional lung perfusion and ventilation-related information…
- Trial name
- FD-COPD (NCT02367209)
- Where
- Switzerland
- Volunteers
- 14 people
- Sponsor
- University Hospital, Basel, Switzerland
Lumbar Disc Herniation, Lumbosacral Radiculopathy
Comparing Three Epidural Steroid Injection Approaches for Lumbar Radicular Pain
This study will compare three fluoroscopy-guided epidural steroid injection approaches for adults with unilateral lumbosacral radicular pain caused by lumbar disc herniation.
- Trial name
- NCT07813988
- Testing
- High-Volume Parasagittal Interlaminar Epidural Steroid Injection, Low-Volume Parasagittal Interlaminar Epidural Steroid Injection, Transforaminal epidural steroid injection
- Where
- Egypt
- Volunteers
- 99 people
- Sponsor
- Benha University
Hepatocellular Carcinoma (HCC) Prognosis, Contrast-enhanced Ultrasound
A Comparative Study on the Diagnostic Efficacy of Ultrasound Contrast LI-RADS Grading and the German ESCULAP Standards for the Diagnosis of Recurrent Hepatic Mass Lesions After Hepatocellular Carcinoma Surgery
Hepatocellular carcinoma (HCC) is the sixth most common malignant tumor worldwide, with a significantly increased incidence among patients with liver diseases.
- Trial name
- NCT07600346
- Testing
- Contrast-Enhanced Ultrasound
- Volunteers
- 105 people
- Sponsor
- The First Hospital of Jilin University
Healthy
Multi-organ Transit Time Acquisition Using Contrast Ultrasound
Echocardiographic contrast will be administered to volunteers for the purpose of measuring transit time through various organs/vascular beds
- Trial name
- NCT05135169
- Testing
- Definity Suspension for Injection
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Colorectal Neoplasm, Hepatic Neoplasm
Metastatic Colorectal Cancer: Treatment Response With Dynamic Contrast MRI
The objectives for this study include: Testing a unique way of imaging people with colorectal cancer and other cancers that has spread to the liver using magnetic resonance imaging (MRI); Seeing if the MRI process can be used…
- Trial name
- NCT00820456
- Testing
- DCE-MRI
- Where
- 5 sites in United States
- Volunteers
- 6 people
- Sponsor
- American College of Radiology
Leakage, Anastomotic, Colon Cancer
COLOFLOW: Laser Speckle Contrast Imaging Versus Near-infrared Fluorescence Imaging With Indocyanine Green
COLOFLOW is a prospective observational study investigating whether Laser Speckle Contrast Imaging (LSCI), a dye-free and objective perfusion imaging technique, corresponds with the currently used subjective assessment of…
- Conditions
- Leakage, Anastomotic, Colon Cancer, Colon Anastomosis, Colon and Rectal Cancer
- Trial name
- COLOFLOW (NCT07720505)
- Testing
- Laser Speckle Contrast Imaging
- Volunteers
- 30 people
- Sponsor
- Leiden University Medical Center
Breast Cancer
Comparison of Positron Emission Mammography and Contrast-enhanced Breast MRI
The hypothesis of this study is that positron emission mammography will provide comparable sensitivity to contrast-enhanced breast MRI in women with a high suspicion of breast cancer.
- Trial name
- PEM/MRI (NCT02770586)
- Testing
- Breast PET
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Contrast Media Allergy
Persistence of Sensitization to Contrast Media
The study aims to evaluate the persistence of IgE-mediated allergy to contrast media (CM) after a second exposure in patients who tested positive at both the first and second evaluations for CM allergy.
- Trial name
- PersensPC (NCT07409051)
- Testing
- Skin testing, Baseline serum tryptase measurement
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Endoleak, Abdominal Aortic Aneurysm
Contrast Enhanced Ultrasound, Endoleak Detection Following EVAR v1.3
A single site cross-sectional comparison of paired diagnostic imaging modalities. This study will show the sensitivity and specificity of CEUS in detecting the various types of endoleaks, in comparison to tCTA, following EVAR.
- Trial name
- NCT02688751
- Testing
- time-resolved CT Angiography, Contrast Enhanced Ultrasound
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Limbal Dermoid
Visual Quality and Contrast Sensitivity Function for Limbal Dermoid Children After Corneal Transplantation
This study is to inquiry the contrast sensitivity function in the 50 eyes of limbal dermoid children with keratoplasty with quick contrast sensitivity function (quick CSF) test, as well asa to analyze its relationship between…
- Trial name
- NCT03447041
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Acute Kidney Injury, The Changes of Plasma Creatinine
Short-Term Alpha Lipoic Acid Therapy for Prevention of Contrast-induced Acute Kidney Injury and Endothelial Dysfunction in Type 2 Diabetes
Contrast-induced acute kidney injury (CIAKI) is a major complication with adverse outcomes after contrast media injection. Although the risk of developing CIAKI is low in patients with normal renal function, it is dramatically…
- Conditions
- Acute Kidney Injury, The Changes of Plasma Creatinine, The Changes of Plasma Free Radicals, The Changes of Endothelium-dependent Arterial Dilation
- Trial name
- NCT01978405
- Testing
- Alpha lipoic acid
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xiang Guang-da
Aortic Aneurysm, Ischemic Preconditioning
Effect of Remote Ischemic Preconditioning on the Incidence of Contrast Induced Nephropathy in Patients Undergoing EVAR
Introduction: Contrast induced nephropathy (CIN) is a major inconvenience in the use of iodinated contrast media (ICM) and it is associated with a significant increase in morbimortality and cost of hospitalization.
- Trial name
- RIPC-EVAR (NCT05350683)
- Testing
- Remote ischemic preconditioning
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Vascular Investigation Network Spanish Society for Angiology and Vascular Surgery