Clinical trials: Contrast Media Reaction
Coronary Artery Disease, Contrast Media Reaction
Iso-Osmolar vs. Low-Osmolar Contrast Agents for Optical Coherence Tomography
The proposed study aims to compare (a) volume contrast administered for Optical Coherence Tomography (OCT) Imaging, (b) length of clear OCT images, and (c) electrocardiographic changes immediately after contrast injection between…
- Trial name
- GE OCT (NCT05065073)
- Testing
- Iodixanol, Iohexol
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Minneapolis Heart Institute Foundation
Contrast Media Adverse Reaction
Effects of Contrast Media Temperature on Image Quality and Clinical Adverse Events in Coronary CTA
Extrinsic prewarming of iodinated CT contrast media (CM) to body temperature reduces viscosity and injection pressures. However, guideline recommendations on the necessity to prewarm iodinated CM are conflicting.
- Trial name
- NCT05489055
- Testing
- Iopamidol
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Chongqing Emergency Medical Center
Contrast Enhanced X-ray Based Examination
A Study, Called UV Population, to Learn More About the Safety of the Study Drug Ultravist, Which is Given to Get Clearer X-ray Pictures, in People of Different Sexes, Races, and From Different Countries/Regions
This is an observational study in which patient data from the past of people who received Ultravist prior to an X-ray based scan are studied.
- Trial name
- NCT05428397
- Testing
- Iopromide (Ultravist, BAY86-4877)
- Where
- Germany
- Volunteers
- 152,233 people
- Sponsor
- Bayer
Acute Kidney Injury, Renal Insufficiency, Chronic
Balanced Salt Solution Versus 0.9% Saline Infusion for Prevention of Contrast-induced Acute Kidney Injury (BASIC Trial)
As iodinate contrast media (CM) has been widely used in current medical practice, contrast induced acute kidney injury (CI-AKI) has been an important issue.
- Conditions
- Acute Kidney Injury, Renal Insufficiency, Chronic, Contrast Media Reaction
- Trial name
- NCT02799368
- Testing
- CJ Plasma Solution A Injection, CJ 0.9% Normal Saline Injection
- Where
- South Korea
- Volunteers
- 493 people
- Sponsor
- Seoul National University Hospital
Acute Kidney Injury, Contrast Media Reaction
PrevenTion of Contrast-inducEd nephroAThy With urinE Alkalinization
Intravascular administration of iodinated contrast media is an essential tool for cardiovascular imaging and percutaneous coronary interventions.
- Trial name
- TEATE (NCT02980003)
- Testing
- isotonic saline, i.v. sodium bicarbonate, oral sodium bicarbonate
- Where
- Italy
- Volunteers
- 240 people
- Sponsor
- G. d'Annunzio University
Color Blindness, Red, Reaction Time
Effect of Protanopia on the Brightness Perception of Brake Lights
The aim of the offered project is to investigate the influence of protanopia (red blindness) or protanomaly (red vision weakness) on the recognizability of red brake lights with the help of a test person study.
- Trial name
- ProLight (NCT04060238)
- Testing
- Anomaloscope (colour vision test)
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Aalen University
Allergic Reaction
Interest of Challenge Tests for Diagnosis of Immediate Hypersensitivity Against Iodinated Contrast Agents
Iodinated contrast agents (ICA) are widely used in medical imaging. They provide however a risk of immediate hypersensitivity reactions (IHS). The risk of anaphylactic shock is estimated at 1/100 000 injections.
- Trial name
- DHIODE (NCT03525496)
- Where
- France
- Volunteers
- 85 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
MRI Contrast Media Adverse Reaction, Bladder Cancer
Can VI-RADS/ADC Accurately Stage Bladder Cancer??
Vesical Imaging-Reporting And Data System (VI-RADS) is proposed for predicting muscle invasive bladder cancer (MIBC) using multi-parametric MRI. However, No validation study on VI-RADS has been reported yet.
- Conditions
- MRI Contrast Media Adverse Reaction, Bladder Cancer, Bladder Disease, Bladder Neoplasm
- Trial name
- NCT04167631
- Testing
- Multi-parametric MRI
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Mansoura University
Contrast Media Reaction, Acute Renal Failure
IVUS Guidance to Reduce Contrast in Coronary Angioplasty
This study tests the hypothesis that ultrasound-guided PCI reduces contrast volume during the procedure.
- Trial name
- MOZART (NCT01947335)
- Testing
- IVUS-guided PCI
- Where
- Brazil
- Volunteers
- 83 people
- Sponsor
- InCor Heart Institute
Adverse Reaction to Drug, Allergic Reaction to Contrast Media
Assessment of Immediate Adverse Reactions From Dotarem in Children Under 2 Years of Age
Our primary outcome is to assess the safety of Dotarem in children <2 years old up to 24 hours after Dotarem injection. Patients will be monitored for any adverse events that occur for 2 hours following the completion of the MRI…
- Trial name
- NCT02609919
- Testing
- Gadoteric Acid
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- St. Louis University
Allergic Reaction to Contrast Media, Hypersensitivity Reaction
1-hour Premedication for Allergy Goal in Emergency: PAGE-1 Study
1-hour Premedication for Allergy Goal in Emergency: PAGE-1 is a prospective, parallel, two-arm, non-inferiority, randomized controlled trial evaluating the safety of a 1-hour (intervention) versus a 4-hour (standard regimen)…
- Conditions
- Allergic Reaction to Contrast Media, Hypersensitivity Reaction, Computed Tomography, Premedication
- Trial name
- PAGE1 (NCT07268248)
- Testing
- IV glucocorticoid and antihistamine, IV glucocorticoid and antihistamine (standard of care)
- Volunteers
- 540 people
- Sponsor
- Paul Peng, MD PhD MSCR
Hyperthyroidism/Thyrotoxicosis, Hyperthyroidism; Goiter
Iodinated Contrast Media Induced Hyperthyroidism
The proper synthesis of thyroid hormones is dependent on adequate iodine supply. The mean daily iodine intake recommended by World Health Organization is 150 mg.
- Conditions
- Hyperthyroidism/Thyrotoxicosis, Hyperthyroidism; Goiter, Iodine Induced Thyrotoxicosis, Contrast Media Adverse Reaction
- Trial name
- NCT04304794
- Testing
- Administration of iodinated contrast media, Prophylactic administration of antithyroid drugs before iodinated contrast media exposure
- Volunteers
- 36 people
- Sponsor
- Medical University of Warsaw
X-ray Contrast Media Adverse Reaction
Preparative Fasting Before Contrast-enhanced Computed Tomography
The study aims to determine whether there is a need for preparative fasting prior to contrast-enhanced computed tomography (CT).
- Trial name
- NCT03533348
- Where
- Israel
- Volunteers
- 2,148 people
- Sponsor
- HaEmek Medical Center, Israel
Venous Insufficiency of Leg, Venous Leg Ulcer
Non Contrast MRI in Lower Extremity
We collected retrospectively the non contrast MRI in chia yi memorial hospital for different venous disease of lower extremity morphology and flow ananlysis were done.
- Conditions
- Venous Insufficiency of Leg, Venous Leg Ulcer, Venous Occlusion, Contrast Media Reaction
- Trial name
- NCT04995432
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Magnetic Resonance Imaging Contrast Media Adverse Reaction, Sedation Complication
Non-operating Room Anesthesia Experiences in Pediatric Magnetic Resonance Imaging Cases
In recent years, out patient anesthesia applications have been increasing for diagnostic and interventional procedures for pediatric patients.
- Trial name
- NCT05423821
- Testing
- Anesthesia efficacy in patients undergoing MRI
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Yunus Emre
CA-AKI - Contrast-Associated Acute Kidney Injury, Coronary Artery Disease
Efficacy of Phentolamine in Prevention of Contrast-Associated Acute Kidney Injury After Complex PCI
To evaluate the efficacy and safety of phentolamine in prevention of CA-AKI following complex PCI in patients at high risk of CA-AKI.
- Conditions
- CA-AKI - Contrast-Associated Acute Kidney Injury, Coronary Artery Disease, Acute Coronary Syndrome, Adrenergic Receptor Antagonist Adverse Reaction
- Trial name
- NCT06286059
- Testing
- Phentolamine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Helwan University
X-ray Contrast Media Adverse Reaction
Bioimpedance Analysis Guided Volume Expansion for the Prevention of Contrast Induced-acute Kidney Injury
Bioelectrical impedance analysis guided volume expansion for the prevention of contrast induced-acute kidney injury
- Trial name
- BELIEVE (NCT02449317)
- Testing
- Bioimpedance guided, standard hydration
- Volunteers
- 56 people
- Sponsor
- Mahidol University
Anxiety, Stress
Assessment of Stress and Anxiety for Patients Undergoing MRI Using, Holy Quran, Music, and Natural Sounds
The aim of the current study is to analyze the effect of listening to Quran or music or natural sounds on anxiety and stress level among patients undergoing MRI.
- Conditions
- Anxiety, Stress, MRI Contrast Media Adverse Reaction
- Trial name
- NCT06348862
- Testing
- Listening to either Quran, Music, and or Natural sound
- Where
- Palestinian Territories
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Al-Quds University
Kidney Diseases, Contrast Media Reaction
A Prospective Study on Incidence and Prevention of Contrast-induced Nephropathy in Croatia
The study is analysis of the incidence of contrast-induced nephropathy (CIN) in patients with previously normal renal function undergoing angiography and comparison between the three different treatment protocols on renal…
- Trial name
- NCT02761577
- Testing
- Sodium bicarbonate, N-acetylcysteine
- Volunteers
- 90 people
- Sponsor
- Clinical Hospital Centre Zagreb
Small Bowel Obstruction, Contrast Media Adverse Reaction
Use of a Water Soluble Contrast-Based Protocol to Assist in the Management of Pediatric Adhesive Small Bowel Obstruction
The goal of this prospective observational study is to evaluate the diagnostic and therapeutic utility of an enteral contrast challenge for pediatric patients with adhesive small bowel obstruction (ASBO). The aims are to 1.
- Trial name
- SBO (NCT06101719)
- Testing
- Enteral contrast challenge
- Where
- 9 sites in United States
- Volunteers
- 136 people
- Sponsor
- Children's Hospital Colorado