Clinical trials: Controlled Diabetes
Type 1 Diabetes, Diabetic Ketoacidosis
Study to Explore the Effect of Dapagliflozin and Stress in Adolescent and Adult Subjects With Type 1 Diabetes (T1D)
Type 1 Diabetes is characterized by an absolute lack of insulin caused by autoimmune ß-cell destruction. Looking for different therapeutic approaches, beyond the administration of Insulin SGLT-Inhibitors (SGLT=sodium-glucose…
- Trial name
- Dapa-Stress (NCT04234867)
- Testing
- Dapagliflozin, Stress
- Where
- Germany
- Volunteers
- 2 people
- Sponsor
- Kinderkrankenhaus auf der Bult
Diabetes Mellitus Type 2
Mulberry Leaf Extract and Blood Glucose Control in Diabetics
Mulberry leaf teas or extracts are used as a natural remedy for diabetes in some countries. Animal studies have shown some effect of mulberry leaf extract on blood glucose.
- Trial name
- NCT01305434
- Testing
- Mulberry leaf extract effect on post prandial blood glucose
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Craig, Nancy, M.D.
Diabetes, Gestational
Postpartum Diabetes Screening in Women With Gestational Diabetes
Assess postpartum diabetes screening in GDM patients with initiation of a reminder system in the postpartum period
- Trial name
- NCT02520336
- Testing
- Reminder
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Comparison of Glycemic Control Among Diabetics Using Three Different Pen Needles
Anxiety about needles is a commonly expressed concern by diabetics about beginning insulin therapy. A shorter, thinner pen needle that delivers insulin with the safety and efficacy profile of currently marketed pen needles may…
- Trial name
- NCT00928057
- Testing
- 4mm x 32G pen needle, 8mm x 31G pen needle, 5mm x 31G pen needle
- Where
- 4 sites in United States
- Volunteers
- 173 people
- Sponsor
- Becton, Dickinson and Company
Diabete Type 1, Diabete Type 2
Effects of LP-LDL® on Lipid Metabolism, Glycemic Control, Inflammatory Markers, and Cognitive Function in Individuals With Prediabetes and Diabetes Mellitus
This randomized, double-blind, placebo-controlled clinical trial investigates the effects of the probiotic LP-LDL® (Lactobacillus plantarum ECGC 13110402) on lipid metabolism, glycemic control, inflammatory biomarkers, and…
- Conditions
- Diabete Type 1, Diabete Type 2, Prediabetes
- Trial name
- NCT07373392
- Testing
- Lactobacillus plantarum ECGC 13110402
- Where
- 2 sites in Denmark
- Volunteers
- 210 people
- Sponsor
- Aalborg University
Type 1 Diabetes
MICHAEL Method- Fulfilling Individual Potential to Attain Excellence - as a Tool for Improving Metabolic Control and Quality of Life Among Adolescence With Type 1 Diabetes
Type 1 diabetes is the most common childhood disease. Treatment of diabetes requires personal checks of blood sugar levels, injecting insulin, changing eating habits and physical exercise, which requires a real change in the life…
- Trial name
- NCT01691287
- Testing
- Michael Method
- Where
- Israel
- Volunteers
- 23 people
- Sponsor
- Rabin Medical Center
Non-alcoholic Steatohepatitis
A Double-blind Study to Assess 2 Doses of an Investigational Product for 16 Weeks in Participants With Non-alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus
This is a double-blind, placebo-controlled study in adults with non-alcoholic steatohepatitis and Type 2 Diabetes Mellitis on stable dose of metformin monotherapy.
- Trial name
- NCT03969719
- Testing
- PF-06835919
- Where
- 106 sites in United States, Canada
- Volunteers
- 164 people
- Sponsor
- Pfizer
Diabetic Foot Ulcer
Evaluating the Efficacy of OCM™ (Omeza® Complete Matrix) in the Treatment of Diabetic Foot Ulcers
This study aims to compare two treatment approaches for diabetic foot ulcers (DFUs): the standard of care (SOC) alone versus SOC combined with OCM.
- Trial name
- NCT07161830
- Testing
- Omeza® Complete Matrix, Standard of Care
- Where
- 10 sites in United States
- Volunteers
- 180 people
- Sponsor
- Omeza, LLC
Diabetes, Foot Ulcer
Use of INTEGRA™ Flowable Wound Matrix to Manage Diabetic Foot Ulcers
After determining if subjects meet the criteria to be included in the study they will be randomly placed in either Group 1 or 2 and patient will be blinded from randomization group.
- Trial name
- NCT01108263
- Testing
- INTEGRA™ Flowable Matrix (Collagen)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Georgetown University
Type 2 Diabetes Mellitus
Drug-Drug Interaction Study of Mitiglinide and Gemfibrozil
The primary objective of this study is to determine the extent of effect of gemfibrozil on the pharmacokinetics and pharmacodynamics of mitiglinide.
- Trial name
- NCT00566865
- Testing
- gemfibrozil
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Elixir Pharmaceuticals
Diabetic Nephropathy
Controlled Study to Evaluate Efficacy and Safety of α-KA Tab With Low Protein Diet (LPD) in Delaying the Progress of Type 2 Diabetic Nephropathy (DN)
Current expert opinion based consensus guidelines recommend usage of α-Keto analogues of essential amino acids in the diet of diabetic nephropathy patients, along with restricted protein diets.
- Trial name
- NCT00363987
- Testing
- Ketosteril®, diabetic diet
- Where
- China
- Volunteers
- 179 people
- Sponsor
- Fresenius Kabi
Diabetes Mellitus, Type 2
Wine Consumption and Glycemic Control
Many studies have reported that alcoholic beverage consumption, especially in the form of wine, reduces the risk of developing type 2 diabetes by as much as 40%.
- Trial name
- WGC (NCT02518334)
- Testing
- Alcohol consumption
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Missouri-Columbia
Diabetes Mellitus, Type 2
A Study in North Macedonia Investigating Retrospective Data of Glucagon-like Peptide-1 (GLP-1) Participants With Type 2 Diabetes (T2D) in Real World Environment (RWE) Setting (MIRAGE)
The purpose of this study is to investigate glycaemic control and other clinical parameters in glucagon like peptide -1 (GLP-1) naive adult participants with type 2 diabetes (T2D) who initiated once weekly (OW) semaglutide in…
- Trial name
- MIRAGE (NCT05468632)
- Testing
- Semaglutide
- Where
- 17 sites in North Macedonia
- Volunteers
- 314 people
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes Mellitus
Placebo Controlled, Dose Escalation Study in Subjects With Type 2 Diabetes Mellitus Being Treated With Sulfonylurea
The purpose of this study is to provide an initial assessment of the safety, tolerability and efficacy of ISIS 113715 in combination with sulfonylurea in type 2 diabetes subjects.
- Trial name
- NCT00455598
- Testing
- ISIS 113715
- Where
- 39 sites in Poland, Romania and 1 more
- Volunteers
- 88 people
- Sponsor
- Ionis Pharmaceuticals, Inc.
Diabete Type 2
Effectiveness of Motivational Interviewing on Improving Care for Type 2 Diabetes Mellitus Patients in China
The International Diabetes Federation estimated that there were nearly 110 million diabetes mellitus (DM) patients in China, which was the highest number recorded in the world.
- Trial name
- NCT04120844
- Testing
- Motivational interviewing (MI)-based patient empowerment program (PEP), Traditional lecture style health education
- Volunteers
- 225 people
- Sponsor
- The University of Hong Kong-Shenzhen Hospital
PreDiabetes, Obesity
Effect of Mango Consumption on Individuals with Pre-diabetes
This study is designed to explore the effect of mango consumption on glycemic indices, cardiovascular health, and body composition in overweight and obese individuals with prediabetes.
- Trial name
- NCT05571800
- Testing
- Mango
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Florida State University
Obesity, Type 2 Diabetes
Effects of Oral Sodium Butyrate Supplementation on Body Weight Reduction in Overweight/Obese Individuals With and Without Type 2 Diabetes
The goal of this clinical trial (randomized controlled trial with parallel group design) is to evaluate the effects of oral sodium butyrate supplementation for 12 weeks, compared with placebo, in addition to a moderately…
- Trial name
- ButRed (NCT07252609)
- Testing
- Sodium Butyrate (NaBut)
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- Federico II University
Type2 Diabetes
Oat Beta-glucan as a Supplement in Chilean Type 2 Diabetics
Objective: To evaluate the effect of oat β-glucans on the satiety perception, metabolic control and intestinal microbiota of type 2 diabetics from Talca, Chile.
- Trial name
- NCT04299763
- Testing
- Oat Beta-glucan as a Supplement in Type 2 Diabetics
- Where
- Chile
- Volunteers
- 37 people
- Sponsor
- Centro de Estudios en Alimentación y Nutrición, Chile
Type1 Diabetes Mellitus
Adolescence and Diabetes:Can an Automated Closed Loop System Improve Control ?
This study evaluates the use of the FD2 automated closed loop insulin administration in Adolescents with a poor metabolic control .
- Trial name
- SPIDIMAN2 (NCT03300934)
- Testing
- closed loop glucose control system
- Where
- Luxembourg
- Volunteers
- 16 people
- Sponsor
- Centre Hospitalier du Luxembourg
Type 2 Diabetes Patients
A Study to Access the Efficacy in Type 2 Diabetes Mellitus on Stable Metformin
This is a randomized, double-blind, placebo-controlled, repeat-dose study to evaluate the safety, tolerability, PK, and PD of L47 as an add-on treatment to stable metformin therapy in patients with T2DM.
- Trial name
- NCT04662164
- Testing
- hepalatide
- Sponsor
- Shanghai HEP Pharmaceutical Co., Ltd.
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