Clinical trials: Controlled Diabetes
Diabetes Complications, Inspiratory Muscle Weakness
Effects of Inspiratory Muscle Training on Type 2 Diabetes Mellitus Patients With Inspiratory Muscle Weakness
The purpose of the study is to determine if inspiratory muscle training improves inspiratory muscle strength of type 2 diabetes mellitus patients with inspiratory muscle weakness.
- Trial name
- NCT00815178
- Testing
- Inspiratory muscle training
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Type 1 Diabetes
Testing MST to Improve Adherence Among Youth With Chronic Poor Metabolic Control
The protocol is a randomized clinical trial providing Multisystemic Therapy (MST), an intensive home-based family psychotherapy intervention, to a group of urban adolescents with poorly controlled Type 1 diabetes and their…
- Trial name
- NCT00519935
- Testing
- Multisystemic Therapy
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- Wayne State University
Type 2 Diabetes Mellitus
Safety and Efficacy Study of Dutogliptin/PHX1149T to Treat Type 2 Diabetes Mellitus
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate Safety and Efficacy of PHX1149T as Monotherapy in Subjects with Type 2 Diabetes Mellitus
- Trial name
- NCT00690638
- Testing
- PHX1149T
- Where
- 62 sites in United States, Argentina and 7 more
- Volunteers
- 480 people
- Sponsor
- Phenomix
Diabetic Nerve Problems, Diabetic Neuropathy
The Efficacy and Safety Profile of Capsaicin 8% Patch Versus 5% Lidocaine Patch in Males With Diabetic Neuropathy
The study aims to compare the effectiveness and tolerability of using lidocaine 5% patch to 8% capsaicin patch in patients with diabetic neuropathy.
- Conditions
- Diabetic Nerve Problems, Diabetic Neuropathy, Diabetic Complications Neurological
- Trial name
- NCT04238208
- Testing
- Lidocaine 5% patch, Capsaicin 8% Patch, Per 10 Square Centimeters
- Where
- Pakistan
- Volunteers
- 290 people
- Sponsor
- Corporacion Parc Tauli
Diabetes, Diabetes Mellitus, Type 2
Treatment Intensification With Biphasic Insulin Aspart 30 in Subjects With Type 2 Diabetes Inadequately Controlled on Sitagliptin and Metformin
This trial is conducted in Asia, Europe, Oceania and South America. The aim of this clinical trial is to generate data demonstrating how to intensify diabetes treatment using BIAsp 30 (biphasic insulin aspart 30) by adding or…
- Trial name
- SIT2MIX (NCT01519674)
- Testing
- biphasic insulin aspart 30, sitagliptin, metformin
- Where
- 69 sites in Argentina, Australia and 8 more
- Volunteers
- 582 people
- Sponsor
- Novo Nordisk A/S
Hypertension, Cardiovascular Disease
Population Based Strategies for Effective Control of High Blood Pressure in Pakistan
Studies have established that high blood pressure (BP) is the most common risk factor for cardiovascular disease (CVD). Despite a heavy burden of hypertension (33% of all persons aged 45 years and over), there are no reliable…
- Conditions
- Hypertension, Cardiovascular Disease, Obesity, Diabetes
- Trial name
- NCT00327574
- Testing
- Home heath education +/_ GP training
- Where
- Pakistan
- Sponsor
- Aga Khan University
Diabetes Mellitus, Kidney Transplant; Complications
Empagliflozin Versus Linagliptin in Renal Ransplant Recipients With Diabetes Mellitus
This EmLina Renal trial is an investigator initiated, single-center, prospective, open-label, randomized clinical study to examine the safety and effect of empagliflozin 25 mg once a day vs.
- Trial name
- EmLina Renal (NCT06098625)
- Testing
- Empagliflozin 25 MG, Linagliptin 5 mg Oral Tablet
- Volunteers
- 200 people
- Sponsor
- Medanta, The Medicity, India
Diabetes Mellitus, Type 1
An Open-label, Two-center, Randomized, Cross-over Study to Evaluate the Safety and Efficacy of Glycemic Control Using Hybrid-closed Loop vs. Advanced Hybrid Closed-loop in Young Subjects With Type 1 Diabetes
Closed-loop systems are becoming an integral part of diabetes management. These systems were uniformly proven to improve glycemic control, reduce hyperglycemia and hypoglycemia while modestly reducing HbA1c levels and improving…
- Trial name
- NCT04269668
- Testing
- Medtronic Minimed 670G 3.0 HCL, Medtronic Minimed 670G 4.0 AHCL
- Where
- 2 sites in Germany, Israel
- Volunteers
- 28 people
- Sponsor
- Rabin Medical Center
Hypertension
Glycemic Control Of Carvedilol Versus Metoprolol In Patients With Type II Diabetes Mellitus And Hypertension
To evaluate the effects of two different antihypertensive medications in the drug class of beta-blockers on control of glucose in Type II diabetic patients with high blood pressure.
- Trial name
- NCT00060918
- Testing
- carvedilol, metoprolol
- Where
- 50 sites in United States
- Volunteers
- 1,210 people
- Sponsor
- GlaxoSmithKline
Diabetic Foot, Chronic Foot Ulcer
Randomized Clinical Study Comparing SynPath to Standard of Care in Treatment of Chronic Diabetic Foot Ulcers
The study will evaluate the efficacy of SynPath™, a synthetic dermal matrix, in the treatment of diabetic foot ulcers in subjects with diabetes mellitus versus Standard of Care treatment.
- Conditions
- Diabetic Foot, Chronic Foot Ulcer, Wound Healing, Foot Ulcer
- Trial name
- DFUs (NCT05506215)
- Testing
- SynPath Acellular Dermal Matrix plus Off-loading Device, Wound Dressing composed of 90% collagen and 10% Alginate plus Off-loading Device
- Where
- 7 sites in United States
- Volunteers
- 25 people
- Sponsor
- PolyNovo Biomaterials Pty Ltd.
Stress, Diabetes Mellitus, Type 2
Decreasing Stress in Diabetes
The purpose of this study is to conduct a randomized controlled trial (RCT) to determine the effects of an online 6-month Mindfulness-based stress reduction (MBSR) intervention compared to an active control Stress Management…
- Conditions
- Stress, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
- Trial name
- De-Stress (NCT04016415)
- Testing
- Mindfulness Based Stress Reduction, Stress Management Education
- Where
- United States
- Volunteers
- 309 people
- Sponsor
- Milton S. Hershey Medical Center
Diabetes Mellitus, Type 2, Diabetic Nephropathy
Evaluation of the Effects of Canagliflozin on Renal and Cardiovascular Outcomes in Participants With Diabetic Nephropathy
The goal of this study is to assess whether canagliflozin has a renal and vascular protective effect in reducing the progression of renal impairment relative to placebo in participants with type 2 diabetes mellitus (T2DM), Stage…
- Trial name
- CREDENCE (NCT02065791)
- Testing
- Canagliflozin
- Where
- 575 sites in United States, Argentina and 32 more
- Volunteers
- 4,401 people
- Sponsor
- Janssen Research & Development, LLC
Apathy, Diabetes
The Role of Apathy in Glycemic Control
In spite of several new medications and insulins for the control of blood sugars in patients with diabetes, a large number of patients do not have good control.
- Trial name
- NCT00844090
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- US Department of Veterans Affairs
Uncontrolled Diabetes, Diabetes Mellitus Type 2
Efficacy of Diacerein Supplementation on Interleukin-1β, Hs-CRP, TNF-α Levels and Glycemic Control in Uncontrolled Type 2 Diabetes Mellitus Patients at Dr. Mohammad Hoesin General Hospital Palembang
The goal of this clinical trial is to learn if diacerein supplementation can help improve inflammation and glycemic control in adults with uncontrolled type 2 diabetes. It will also study the safety and tolerability of diacerein.
- Trial name
- NCT06912035
- Testing
- Diacerein 50 mg Capsule
- Where
- Indonesia
- Volunteers
- 34 people
- Sponsor
- Universitas Sriwijaya
Type 2 Diabetes, Obesity
Remission of Diabetes With Lifestyle Intervention for Malaysian Patients
This study aims to evaluate the effectiveness of structured lifestyle intervention to induce remission of Type 2 Diabetes Mellitus (T2DM) among Malaysian adults.
- Trial name
- ReDiaL-MY (NCT07270068)
- Testing
- Total Diet Replacement, Standard of Care
- Where
- 2 sites in Malaysia
- Volunteers
- 92 people
- Sponsor
- Winnie Chee Siew Swee
Diabetes Mellitus, Type 2
Sucralose in Subjects With Diabetes Mellitus Insulin Requesting
To evaluate the acute effect of a preload of sucralose in presence of carbohydrate (HC) available on the glycemic response, postprandial C peptide and satiety in patients with type 2 diabetes mellitus (DM2) in intensive insulin…
- Trial name
- SDMIR (NCT02813759)
- Testing
- Sucralose
- Volunteers
- 10 people
- Sponsor
- Universidad de Valparaiso
Diabetes Mellitus, Non-Insulin Dependent
Evaluation of SCOUT DS in Subjects With Type 2 Diabetes #2
The primary objective of the trial is to collect SCOUT DS and Hemoglobin A1c measurements of subjects who have been diagnosed with Type 2 diabetes.
- Trial name
- TCOYD2 (NCT01346046)
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- VeraLight, Inc.
Cognition, Diabetes Mellitus, Type 2
Adaptive Cognitive Training on Cognitive Function in Elderly Diabetes Patients in the Community
Objective A growing body of evidence supports diabetes as a risk factor for cognitive decline. Diabetes is significantly associated with accelerated cognitive decline, poorer cognitive function, and mild cognitive impairment and…
- Conditions
- Cognition, Diabetes Mellitus, Type 2, Aging
- Trial name
- NCT06524388
- Testing
- adaptive cognitive training
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Fanfan Zheng
Continuous Glucose Monitoring, Diabetes, Gestational
Early Pregnancy Lifestyle and Glucose Patterns: A Substudy of TOFFFY
The goal of this clinical trial is to examine how daily behavioral patterns in early pregnancy, including sleep, physical activity, and meal timing, influence continuous glucose dynamics and subsequent risk of gestational…
- Conditions
- Continuous Glucose Monitoring, Diabetes, Gestational, Diet During Pregnancy, Meal Time
- Trial name
- NCT07534670
- Testing
- Continuous glucose monitor (CGM), Wrist actigraphy device, AI-based dietary and meal timing logging mobile application
- Where
- Singapore
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Intervention
To Evaluate the Impact of Consumption of Bioactive Compounds Extracted From Hemp Hull and Black Pepper on Fasting Blood Glucose Levels in People With Pre-diabetes: A Randomized Placebo-Controlled Parallel Arm Trial
This is randomized controlled parallel arm study on free living Asian Indians. Eligible subjects will undergo one-week run-in period and subjects will be asked to maintain their usual diet and exercise regime.
- Trial name
- NCT06454773
- Testing
- NCT/NFT
- Where
- India
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Diabetes Foundation, India
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