Clinical trials: Controlled Diabetes
Impact of Structured DTTP on Quality of Life, Insulin Therapy
Structured Patient Education and Quality of Life of Elderly Patients With Diabetes Mellitus- a Prospective Study
The improvement of the quality of life (QoL) is one of the key treatment goals in patients with diabetes mellitus. Objective: Prospective study to evaluate the impact of structured diabetes education on the QoL in…
- Conditions
- Impact of Structured DTTP on Quality of Life, Insulin Therapy, Metabolic Control, Psychological Aspects
- Trial name
- NCT00444483
- Testing
- Structured diabetes teaching and treatment program
- Volunteers
- 50 people
- Sponsor
- Heidelberg University
Prediabetes / Type 2 Diabetes
Effects of Exercise Prediabetic Individuals
The aim of this study was to determine the effects of two different exercise protocols on body composition, aerobic capacity, blood lipid profile, some biomarkers, quality of life and exercise beliefs in participants at risk of…
- Trial name
- NCT06831266
- Testing
- High Intensity Interval Training (HIIT), Moderate Intensity Continuous Training (MICT)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Eastern Mediterranean University
Diabetes Mellitus
DSME or DSME + MI in T1DM on Glycemic Control
This study evaluates the effect of diabetic knowledge and self care behavior (DSME) alone or DSME plus motivational interviewing on glycemic control among children and adolescents with DM type 1.
- Trial name
- NCT03104829
- Testing
- Motivational interviewing, DSME participants in this arm will receive standard care for diabetes (DSME) at the beginning of the study and 3 months later
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Obesity
Efficacy and Safety of HDM1005 Compared to Tirzepatide in Obese Adults Without Diabetes
This is a 56-week randomized, open-label, controlled study evaluating the efficacy and safety of the HDM1005 compared to tirzepatide in adults with obesity but without diabetes.
- Trial name
- NCT07521631
- Testing
- HDM1005 dose level 1, HDM1005 dose level 2, HDM1005 dose level 3
- Where
- China
- Volunteers
- 372 people
- Sponsor
- Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
Diabetes Mellitus, Type 2
GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation in Monotherapy (GETGOAL-MONO Japan LTS)
The purpose of this study is to compare the benefits and risks of lixisenatide (AVE0010) used as 2-step initiation regimen and 1-step initiation regimen in Japan, over a period of 24 weeks of treatment, followed by an extension…
- Trial name
- GETGOAL-MONO (NCT00905255)
- Testing
- Lixisenatide (AVE0010), Pen auto-injector
- Where
- Japan
- Volunteers
- 69 people
- Sponsor
- Sanofi
Type 2 Diabetes
Lifestyle Control of Postprandial Hyperglycemia
Large spikes in blood glucose experienced after meals in people with type 2 diabetes are known to damage blood vessels. Low carbohydrate high fat diets and exercise can improve blood glucose control in people with type 2 diabetes…
- Trial name
- NCT02683135
- Testing
- High-carbohydrate diet, Low-carbohydrate diet, Low-carbohydrate diet with post-meal walking
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of British Columbia
Non Alcoholic Fatty Liver Disease, Type2 Diabetes Mellitus
Effect of Dulaglutide on Liver Fat in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease
This D-LIFT (Effect of dulaglutide on Liver Fat) trial is an investigator initiated, prospective, open label, randomized clinical study to examine the effect of dulaglutide 0.75 mg subcutaneously weekly for 4 weeks, followed by…
- Trial name
- D-LIFT (NCT03590626)
- Testing
- Dulaglutide
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Medanta, The Medicity, India
Type 2 Diabetes Mellitus
Organization Program of DiabEtes INsulIN ManaGement
Diabetes is a common, costly condition associated with significant morbidity and mortality. Diabetes self-management education, the process of teaching individuals to manage their diabetes, has been considered an important part.
- Trial name
- OPENING (NCT01338376)
- Testing
- Structured Education, Conventional Diabetes Education, Scilin®M30
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Chinese Diabetes Society
Diabetes Mellitus, Type II
Metformin Add-on Study in Patients With Type 2 Diabetes Mellitus (0431-020)(COMPLETED)
The purpose of this study is to determine the safety and efficacy of an investigational drug in patients with type 2 diabetes mellitus.
- Trial name
- NCT00086515
- Testing
- Sitagliptin (MK0431), Metformin, Pioglitazone
- Volunteers
- 701 people
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes Mellitus, Type 2
A 12-week Digital Physical Activity Programme, With or Without Physical Education Support for Type 2 Diabetes Patients.
Investigation into the effects of a 12-week digital physical activity programme, with or without physical education support on blood glucose control in patients with T2DM using HbA1c testing.
- Trial name
- NCT06402578
- Testing
- HbA1c testing
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Queen Margaret University
Diabetes
Free Test Strips and Blood Glucose Control
This study is designed to determine if there is an impact on blood glucose control in patients who receive free test strips. Patients in the study have no insurance or insurance that does not cover the purchase of test strips.
- Trial name
- NCT00205335
- Testing
- Ascencia Breeze Glucose meter, Breeze Glucose Monitor (Bayer)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Wisconsin, Madison
Gastroparesis, Diabetes Mellitus
A Safety and Efficacy Study of Relamorelin in Diabetic Gastroparesis 01
This study will evaluate the safety and efficacy of relamorelin compared to placebo in participants with diabetic gastroparesis. Participants will report daily severity scores of their diabetic gastroparesis symptoms.
- Trial name
- NCT03285308
- Testing
- Relamorelin
- Where
- 216 sites in United States, Australia and 12 more
- Volunteers
- 336 people
- Sponsor
- Allergan
Diabetes Mellitus, Type 1
International Diabetes Closed Loop (iDCL) Trial: Research Site Training Protocol
The objective of the study is for clinical staff to gain experience using the proposed artificial pancreas system named inControl and the inControl Cloud and assess 24/7 in-home usability prior to initiating a large randomized…
- Trial name
- NCT02844517
- Testing
- Artificial Pancreas
- Where
- 10 sites in United States, France and 2 more
- Volunteers
- 43 people
- Sponsor
- University of Virginia
Gastroparesis
G-POEM for Glycemic Control in Diabetic Gastroparesis
Gastroparesis, commonly caused by diabetes, affects 30-50% of diabetic individuals and complicates glycemic control due to its bidirectional relationship with blood glucose levels. Current treatments are often ineffective.
- Trial name
- DIAPOEM (NCT06965543)
- Testing
- Immediate G-POEM, Delayed G-POEM
- Volunteers
- 40 people
- Sponsor
- French Society of Digestive Endoscopy
Diabetes Type 2, Hyperglycaemia (Diabetic)
Effect of Hyperglycaemia and Moxifloxacin on QTc Interval in T2DM
Diabetes is a significant risk factor for sudden cardiac death, with the QTc interval on electrocardiograms (ECGs) often prolonged in diabetic patients due to factors such as hyperglycaemia and insulin resistance.
- Conditions
- Diabetes Type 2, Hyperglycaemia (Diabetic), QT Interval, Variation in, Torsades de Pointes
- Trial name
- NCT07014735
- Testing
- glucose, moxifloxacin
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- Richmond Pharmacology Limited
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Tavua, Fiji
Ambient air temperatures in Fiji are increasing due to climate change. Solutions are needed to build heat resilience in communities and adapt.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- NCT07592117
- Testing
- Cool roof
- Where
- Fiji
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Diabetes Mellitus, Type 2
Study to Examine the Effect on Glucose Control and Safety/Tolerability of Exenatide Given Two Times a Day to Subjects With Type 2 Diabetes
This open label study is designed to assess long term glucose control, as measured by hemoglobin A1c (HbA1c) and to evaluate long term safety and tolerability in subjects with type 2 diabetes mellitus who receive subcutaneously…
- Trial name
- NCT00111540
- Testing
- exenatide
- Where
- 60 sites in United States
- Volunteers
- 456 people
- Sponsor
- AstraZeneca
ESRD, Diabetes
IMPENDIA- PEN VS Dianeal Only Improved Metabolic Control In Diabetic CAPD and APD Patients
Primary Objective: To demonstrate that use of glucose sparing prescriptions (PEN vs Dianeal only) in diabetic (Type 1 and Type 2) Continuous Ambulatory Peritoneal Dialysis (CAPD) and Automated Peritoneal Dialysis (APD)patients…
- Conditions
- ESRD, Diabetes, CAPD, APD
- Trial name
- Impendia (NCT00567489)
- Testing
- Physioneal, Dianeal, Extraneal
- Where
- 19 sites in Hong Kong, Russia and 3 more
- Volunteers
- 137 people
- Sponsor
- Vantive Health LLC
Diabetic Peripheral Neuropathic Pain
Effect of NRD135S.E1 in Peripheral Neuropathic Pain in Diabetic Patients
A multicenter, Phase 2a, randomized, double-blind, placebo (vehicle)-controlled, parallel-group, dose-finding study designed to evaluate the efficacy, safety and tolerability of NRD135S.E1 in adult patients with diabetes mellitus…
- Trial name
- NCT02345291
- Testing
- NRD135S.E1
- Where
- 10 sites in Israel
- Volunteers
- 88 people
- Sponsor
- Novaremed Ltd.
Diabetes, Hyperglycemia
In-Hospital Hyperglycemia: Effects of Treatment on Glycemic Control and Clinical Outcome
To improve glycemic control of inpatients admitted to the internal medicine wards, the researchers generated a protocol based on intensive insulin treatment for use in all inpatients with hyperglycemia.
- Trial name
- NCT00302874
- Testing
- Implementation of a protocol for treatment of hyperglycemia
- Where
- Israel
- Volunteers
- 400 people
- Sponsor
- Hadassah Medical Organization
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