Clinical trials: Controlled Diabetes
Type2diabetes, Disordered Eating
ARIADNE: A Study of Weight Loss for Diabetes Treatment and Wellbeing
The NHS has started a trial-run of a weight loss programme replacing food with 800-calorie shakes and soups for 3 months, offered to people with newly diagnosed type 2 diabetes (T2D) to lose weight and put their diabetes into…
- Conditions
- Type2diabetes, Disordered Eating, Obesity, Overweight and Obesity
- Trial name
- NCT05744232
- Testing
- Low calorie total diet replacement, Usual care
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Diabetes Mellitus, Type 2
Efficacy of Vildagliptin 100 MG as Compared to Placebo as Add-on to Metformin in Patients With Type 2 Diabetes
Vildagliptin is an oral anti-diabetic agent. This is a 24-week study to assess the efficacy on HbA1c of 100 mg vildagliptin once daily as compared to placebo as add-on to metformin in patients with type 2 diabetes inadequately…
- Trial name
- NCT00351884
- Testing
- Vildagliptin AM, vildagliptin pm
- Where
- 2 sites in United States, Germany
- Volunteers
- 370 people
- Sponsor
- Novartis Pharmaceuticals
Type 2 Diabetes Mellitus
DBPR108 Tablets in Type 2 Diabetes Mellitus Patients
This study evaluate DRBP108 in the treatment of type 2 diabetes mellitus. The patients were randomly allocated to four groups: 50 mg, 100 mg, 200 mg and placebo group.
- Trial name
- NCT04124484
- Where
- China
- Volunteers
- 276 people
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Cardiovascular Disease
Cardiovascular Inflammation Reduction Trial
The Cardiovascular Inflammation Reduction Trial (CIRT) is a randomized clinical trial investigating whether taking low-dose methotrexate reduces heart attacks, strokes, or death in people with type 2 diabetes or metabolic…
- Trial name
- CIRT (NCT01594333)
- Testing
- Methotrexate
- Where
- 470 sites in United States, Canada and 1 more
- Volunteers
- 4,786 people
- Sponsor
- Brigham and Women's Hospital
Diabetes Mellitus Type 1
The Effect of Supplementation With Two Different Doses of Vitamin D on Bone Mineral Density, Vitamin D Levels and Hand Grip Strength in Children With Diabetes Mellitus Type 1
The aim of the study is to assess the effect of 12 month supplementation with two different doses of vitamin D ( 500 vs 1000) on bone mineral density, serum 25 hydroxyvitamin D levels and hand grip strength in preadolescents with…
- Trial name
- NCT01277913
- Testing
- Vitamin D3
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Warsaw
Diabetes Mellitus, Type 1
A Research Study to Compare a New Weekly Insulin, Insulin Icodec, and an Available Daily Insulin, Insulin Degludec, Both in Combination With Mealtime Insulin in People With Type 1 Diabetes (ONWARDS 6)
This study compares insulin icodec (a new insulin) to insulin degludec (an insulin already available on the market) in people with type 1 diabetes.
- Trial name
- ONWARDS 6 (NCT04848480)
- Testing
- insulin icodec, insulin degludec, insulin aspart
- Where
- 130 sites in United States, Austria and 10 more
- Volunteers
- 582 people
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes Mellitus
How Improvement in Control of Diabetes Influences the Production of a Hormone Produced in the Gut Which Improves the Release and Action of Insulin.
The study is aimed at Type 2 Diabetics who are taking Metformin, but whose Diabetes remains poorly controlled. There are two additional medications already in use, Glimepiride and Sitagliptin will be compared to assess levels of…
- Trial name
- MSD-GLP1 (NCT00747383)
- Testing
- Glimepiride, Sitagliptin
- Where
- United Kingdom
- Volunteers
- 74 people
- Sponsor
- The Royal Bournemouth Hospital
Neuropathic Pain, Neuropathy;Peripheral
The Effect of Lacosamide in Peripheral Neuropathic Pain
The main purpose of this study is to compare the change in pain intensity during treatment with a sodium-channel blocker (lacosamide) in patients with peripheral neuropathic pain with and without the irritable nociceptor…
- Conditions
- Neuropathic Pain, Neuropathy;Peripheral, Neuropathy, Painful, Neuropathy, Diabetic
- Trial name
- NCT03777956
- Testing
- Lacosamide
- Where
- Denmark
- Volunteers
- 63 people
- Sponsor
- Danish Pain Research Center
Type 2 Diabetes
The Effect of Nexium and Probiotics on Insulin Secretion and Cardiovascular Risk Factors in Patients With Type 2 Diabetes
To test the effect of Nexium and probiotics on insulin secretion and cardiovascular risk factors on type 2 diabetic patients. Study Hypothesis: 1.
- Trial name
- Nexium (NCT00699426)
- Testing
- nexium, Yoghurt
- Volunteers
- 41 people
- Sponsor
- Lise Tarnow
Diabetes Mellitus
Women in Control: A Virtual World Study of Diabetes Self-Management
This study evaluates the comparative effectiveness of a diabetes self management (DSM) group medical visit in the virtual world (Second life) verses a face-to-face format, aimed to increase physical activity and improve glucose…
- Trial name
- NCT02726425
- Testing
- Diabetes Self Management Medical Group Visits
- Where
- United States
- Volunteers
- 309 people
- Sponsor
- Boston Medical Center
Type 2 Diabetes Mellitus (T2DM)
Spiritual Care for Psychological and Glycemic Outcomes in Type 2 Diabetes
This study aims to evaluate the effects of integrating spiritual care into the management of patients with type 2 diabetes mellitus.
- Trial name
- SC-DMT2 (NCT07333625)
- Testing
- Spiritual Care Program, Standard Diabetes Care
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- Universitas Noor Huda Mustofa
T2DM (Type 2 Diabetes Mellitus), Dyslipidemias
To Assess With Ezefeno Tab. in Patients With Dyslipidemia and T2DM
The goal of this Randomized controlled trials is to assess in the long term efficacy and safety of ezefeno. The primary endpoint are: major adverse cardiovascular events within 48 months of the trial duration microvascular events…
- Trial name
- ENSEMBLE (NCT06293417)
- Testing
- Ezetimibe/fenofibrate (Ezefeno) and moderate-intensity statin, Dose escalation of moderate-intensity statin
- Where
- South Korea
- Volunteers
- 3,958 people
- Sponsor
- Korea University Anam Hospital
Influenza-like Illness
Biobran/MGN-3 Increases Innate Resistance and Reduces the Incidence of Influenza-like Illnesses
Influenza is a seasonally-epidemic viral infection causing 3-5 million severe illnesses and up to approximately 500,000 annual deaths around the world.
- Trial name
- NCT04646980
- Testing
- Biobran/MGN-3
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Zagazig University
Diabetes, Diabetes Mellitus, Type 2
The Effect of Insulin Detemir on Blood Glucose Control in Taiwanese Patients With Type 2 Diabetes Failing on OAD
The trial is conducted in Asia. The aim of the trial is to evaluate the effect of insulin detemir on blood glucose control in Taiwanese patients with type 2 diabetes failing on OAD with/without once-daily NPH Insulin treatment.
- Trial name
- NCT00521690
- Testing
- insulin detemir
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Novo Nordisk A/S
Overweight or Obese Participants Without Diabetes
A Study to Evaluate Efficacy and Safety of BGM0504 Tablets in Overweight or Obese Participants Without Diabetes
To evaluate the efficacy of BGM0504 tablets compared with placebo in reducing body weight in overweight or obese participants without diabetes after 20 weeks of treatment.
- Trial name
- NCT07658560
- Testing
- BGM0504 tablets
- Where
- China
- Volunteers
- 200 people
- Sponsor
- BrightGene Bio-Medical Technology Co., Ltd.
Diabetic Foot Ulcers
Dehydrated Human Umbilical Cord Allograft in the Management of Diabetic Foot Ulcers
A Multicenter, Prospective, Randomized Controlled Comparative Parallel Study To determine the safety and effectiveness of EpiCord as compared to standard of care (SOC) therapy for the treatment of chronic, non-healing diabetic…
- Trial name
- NCT02844660
- Testing
- EpiCord, Standard of Care
- Where
- 13 sites in United States
- Volunteers
- 130 people
- Sponsor
- MiMedx Group, Inc.
Diabetes, Diabetes Mellitus, Type 2
Effect of Liraglutide or Glimepiride Added to Metformin on Blood Glucose Control in Subjects With Type 2 Diabetes
This trial is conducted in Asia. The trial is designed to compare the effect on glycaemic control of liraglutide or glimepiride added to metformin in subjects with type 2 diabetes
- Trial name
- NCT00614120
- Testing
- liraglutide, glimepiride, metformin
- Where
- 50 sites in China, India and 1 more
- Volunteers
- 929 people
- Sponsor
- Novo Nordisk A/S
Diabetic Nephropathy
Naoxintong Capsule for Diabetic Nephropathy With Dampness Retention Pattern: A Multicenter, Randomized, Double-Blind, Placebo-Controlled TrialAcronymNXT-DKD
Diabetic nephropathy (DN) is a leading cause of end-stage kidney disease worldwide and is associated with a high risk of cardiovascular events and mortality.
- Trial name
- NXT-DKD (NCT07698223)
- Testing
- Naoxintong Capsule
- Where
- 8 sites in China
- Volunteers
- 410 people
- Sponsor
- Chen Xiangmei
Atrial Fibrillation (AF), Heart Failure
Somatic Health Screening for Adults in Outpatient Psychiatric Care in Denmark (SomaScreen)
People with severe mental illness have a substantially increased risk of undiagnosed and insufficiently treated somatic disease.
- Conditions
- Atrial Fibrillation (AF), Heart Failure, Asthma (Diagnosis), Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- SomaScreen (NCT07518446)
- Testing
- Somatic Health Screening for Adults in Outpatient Psychiatric Care in Denmark (SomaScreen)
- Where
- Denmark
- Volunteers
- 2,800 people
- Sponsor
- Amager Hospital
PreDiabetes
Efficacy of Physical Exercise on Glucose Control in People With Prediabetes (GLYCEX) - Phase II
Aim: To assess the efficacy of different frequencies of physical exercise on glycaemic control in adults with prediabetes. Methods: parallel, randomised, controlled, clinical trial will be carried out, with a total of 90…
- Trial name
- GLYCEX (NCT05658770)
- Testing
- 5 days/ week, 3 days/ week, 2 days/ week
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of the Balearic Islands
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