Clinical trials: Controlled Hypertension
Pregnancy Complications
The ADRB3 Receptor in Pregnancy
The primary overall objective of this study is to characterize the levels of and compare levels of the ADRB3 receptor in human non-pregnant myometrium, pregnant myometrium at different time points in pregnancy, in normal and…
- Trial name
- NCT02381106
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska Institutet
Cardiovascular Diseases, Heart Diseases
Urban African-American Community Hypertension Control
To investigate whether a health education program, developed in partnership with the community and delivered by nurse supervised community health workers (CHWs), lowered high blood pressure (HBP) in inner city African American…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension
- Trial name
- NCT00005706
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
HELLP Syndrome
Study of Prognostic Values of Platelet Indices and Inflammatory Markers in Patients With HELLP Syndrome.
This study aims to evaluate the prognostic values of platelet indices and inflammatory markers in patients with HELLP syndrome as:- :-Primary outcome To investigate prognostic values of platelet indices and. .
- Trial name
- NCT07377786
- Testing
- Group I: 30 patients with HELLP syndrome
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Arterial Hypertension
Temperature-elevating Armbaths for Arterial Hypertension
The goal of this randomized controlled trial is to learn about the effect of a hydrotherapeutic approach - a temperature-elevating armbath - in people with arterial hypertention.
- Trial name
- NCT05928702
- Testing
- temperature-elevating armbath
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Kliniken Essen-Mitte
Primary Open Angle Glaucoma
Multicenter Ab-interno Glaucoma Study Investigating Canaloplasty
A prospective, multicenter, randomized, single-masked clinical trial to evaluate the effectiveness outcomes of canaloplasty performed as a standalone procedure with the iTrack microcatheter to the Omni surgical system, and to…
- Trial name
- MAGIC (NCT04769453)
- Testing
- Canaloplasty using the iTrack microcatheter with Healon GV Pro, Canaloplasty using the Omni surgical system with Healon GV Pro, Canaloplasty using the iTrack microcatheter with Healon Pro
- Where
- 7 sites in United States
- Volunteers
- 20 people
- Sponsor
- Nova Eye, Inc.
Hypertension
Hypertension and Retinal Microvascular Dysfunction
Hypertension is a worldwide health care burden that affects the structure and function of the macro- and microcirculation. Non-invasive vascular biomarkers are essential to timely diagnose end organ damage to improve…
- Trial name
- HyperVasc (NCT04763005)
- Testing
- HIIT exercise intervention, Physical activity recommendations
- Where
- Switzerland
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Basel
Portal Hypertension, Cirrhosis
Esophageal Capsule Endoscopy in Children
The portal hypertension (PHT) is the main complication in patients presenting with cirrhosis. It can be the direct cause of bleeding by rupture of the esophageal or gastric varices and can also contribute to the development of…
- Trial name
- PREVOCAP (NCT01551966)
- Testing
- Wireless esophageal capsule endoscopy ( PillCam Eso2)
- Where
- 7 sites in France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Postmenopause, Hypertension
Effects of Angeliq and Prempro on Blood Pressure and Sodium Sensitivity in Postmenopausal Women With Prehypertension
The main purpose of this study is to compare the effects of treatment of two different formulations of Angeliq® and Prempro on blood pressure in post-menopausal women with prehypertension.
- Conditions
- Postmenopause, Hypertension, Pre-Hypertension
- Trial name
- NCT00420342
- Testing
- Drospirenone/17ß-estradiol (Angeliq, BAY86-4891), SH K 00641 C - Medroxyprogesterone acetate / conjugated equine (Prempro TM)
- Where
- 9 sites in United States
- Volunteers
- 92 people
- Sponsor
- Bayer
Metabolic Syndrome, Elevated Blood Pressure
Evaluation of a Nigella Sativa Extract (10% Thymoquinone, Nisatol®) in Perimenopausal Women With Metabolic Syndrome
A prospective, multicenter, randomized controlled study evaluating the efficacy and safety of a Nigella sativa extract standardized to 10% thymoquinone (Nisatol®) in perimenopausal women with metabolic syndrome.
- Trial name
- NCT07013058
- Testing
- Nigella sativa extract (Nisatol®), Mediterranean Diet
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Hypertension
Measuring Adherence to Control Hypertension
The purpose of this study is to test whether accurately measuring patients' adherence to their blood pressure medications with electronic pillbox monitors and then providing clinicians with this information can improve the…
- Trial name
- MATCH (NCT01257347)
- Testing
- Disclosure of adherence report to clinician, MedSignals pillbox
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Columbia University
Hypertension
Cardiovascular Autonomic Control Evaluation Through Cardiac Frequency Variability in Hypertensive Patients
Analyzing cardiovascular evaluation measures in the multidisciplinary and in the conventional treatment of hypertensive patients will provide better parameters for comparing the two approaches.
- Trial name
- NCT02211248
- Testing
- Multidisciplinary assistance, Conventional treatment and follow up
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Hypertension
A Clinical Study to Compare the Safety and Efficacy of an Aliskiren-based Regimen With a Lisinopril Based Regimen in Patients With Severe Hypertension
To compare the safety and efficacy of an aliskiren-based regimen to a lisinopril-based regimen in the treatment of severe hypertension
- Trial name
- NCT00219050
- Testing
- aliskiren
- Where
- 4 sites in Germany, Hungary and 2 more
- Volunteers
- 180 people
- Sponsor
- Novartis
Intrahepatic Cholangiocarcinoma (Icc)
Intraarterial Therapies Plus Tislelizumab Plus Lenvatinib Versus Tislelizumab Plus Gemcitabine-Cisplatin in Unresectable Intrahepatic Cholangiocarcinoma
This is a phase III, multicenter, open-label, randomized controlled trial designed to evaluate the efficacy and safety of arterially directed therapy in combination with tislelizumab plus lenvatinib compared with gemcitabine and…
- Trial name
- RAINBOW (NCT07691515)
- Testing
- Gemcitabine, Cisplatin, Tislelizumab
- Where
- 21 sites in China
- Volunteers
- 140 people
- Sponsor
- Zhejiang Cancer Hospital
Elevated Intracranial Pressure (ICP)
Optic Nerve Sheath Diameter (ONSD) With the Raised PCO2 and Internal Jugular Venous Occlusion
Monitoring the ICP is the most important aspect of the management of these patients. Recently, transorbital ultrasonography has gained popularity as a noninvasive bedside exam that has been shown to be useful in the diagnosis of…
- Trial name
- NCT02361658
- Testing
- Ultrasonographic of the optic nerve sheath diameter, RespirAct™, Neck collar
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lashmi Venkatraghavan
Pre-Eclampsia
Esomeprazole for the Prevention of Preeclampsia
Preeclampsia, one of the hypertensive disorders of pregnancy, remains a leading cause of maternal death worldwide, with the majority of deaths occurring in developing countries.
- Trial name
- NCT03717740
- Testing
- Esomeprazole
- Where
- Egypt
- Volunteers
- 1,000 people
- Sponsor
- Aswan University Hospital
Hypertension
Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Dose Regimens of BIA 5-453
The purpose of this study was to characterise the plasma and urine pharmacokinetic profile of Etamicastat (BIA 5-453) and its metabolites after three multiple rising dose regimens of Etamicastat (BIA 5-453).
- Trial name
- NCT03099226
- Testing
- BIA 5-453
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Bial - Portela C S.A.
Essential Hypertension
Efficacy and Safety of Azilsartan in Participants With Mild to Moderate Uncomplicated Essential Hypertension
The purpose of this study was to evaluate the dose-response relationships of azilsartan, once daily (QD) in participants with mild to moderate uncomplicated essential hypertension.
- Trial name
- NCT01289132
- Testing
- Azilsartan, Candesartan cilexetil
- Volunteers
- 926 people
- Sponsor
- Takeda
Gastric and Esophageal Varices
Hemodynamic Effects of Terlipressin and High Dose Octreotide
The purpose of the study is to find patients's response to terlipressin and octreotide during hepatic venous pressure gradient measurement by observing portal and systemic hemodynamics.
- Trial name
- HEofT&O (NCT02119884)
- Testing
- Terlipressin, Octreotide
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Shanghai Zhongshan Hospital
Type 2 Diabetes, Coronary Artery Disease
Intensive Blood Pressure and LDL Lowering in Diabetic Patients With Coronary Artery Disease
The purpose of this study is to determine whether intensive blood pressure and low density lipoprotein (LDL) cholesterol lowering could improve survival and cardiovascular outcome in Japanese diabetic patients with coronary…
- Conditions
- Type 2 Diabetes, Coronary Artery Disease, Hypertension, Dyslipidemia
- Trial name
- NCT01422421
- Testing
- intensive control, standard control
- Where
- 2 sites in Japan
- Volunteers
- 798 people
- Sponsor
- Takeshi Morimoto
Liver Cirrhosis, Ascites Hepatic
Early TIPS in Patients With Liver Cirrhosis and Ascites
The aim of this clinical trial is to compare the safety and efficacy of transjugular intrahepatic portosystemic shunt (TIPS) implantation with standard treatment (diuretic medications, and if necessary, paracenteses) in patients…
- Conditions
- Liver Cirrhosis, Ascites Hepatic, Portal Hypertension
- Trial name
- eTIPS (NCT06576934)
- Testing
- Transjugular intrahepatic portosystemic shunt (TIPS)
- Where
- Germany
- Volunteers
- 134 people
- Sponsor
- University Hospital Freiburg
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.