Clinical trials: Controlled Hypertension
Intracerebral Hemorrhage, Hypertension
Huayu Jiedu Formula (FTFY-919) Granules Versus Traditional Decoction for Acute Hypertensive Intracerebral Hemorrhage
This is a multicenter, randomized, double-blind, controlled, non-inferiority clinical trial to evaluate the efficacy and safety of Huayu Jiedu Formula (FTFY-919) Chinese medicine formula granules compared with traditional…
- Trial name
- CHAIN3 (NCT07801599)
- Testing
- Huayu Jiedu Formula (FTFY-919) Granules, Huayu Jiedu Formula (FTFY-919) Traditional Decoction
- Volunteers
- 300 people
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Hypertension
The Effects of Device-guided Breathing Exercises on Blood Pressure in Patients With Hypertension
The purpose of this study is to determine whether breathing-exercises with the Resperate or listening to a discman with freely chosen music are effective in the treatment of hypertension
- Trial name
- NCT00594048
- Testing
- Resperate, discman with freely chosen music
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Medical Research Foundation, The Netherlands
Hypertension
Advanced Practice Nurse Intervention Versus Usual Care for Hypertension Control
Hypertension is the most frequent chronic pathology in France and in the world. It is one of the main modifiable cardiovascular risk factors.
- Trial name
- NCT04448249
- Testing
- APN intervention
- Where
- France
- Volunteers
- 330 people
- Sponsor
- Hotel Dieu University Hospital, France
Type 2 Diabetes Mellitus, Obesity
The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes
This research study is being performed to begin to determine the effectiveness of two dominant bariatric surgery procedures versus an intensive lifestyle intervention to induce weight loss in patients and promote improvements in…
- Trial name
- TRIABETES (NCT01047735)
- Testing
- Roux-en-Y Gastric Bypass Surgery, Laparoscopic Adjustable Gastric Banding, Lifestyle Weight Loss Intervention
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Pittsburgh
Open Angle Glaucoma
Combined Phacoemulsification With iStent Inject W Versus Hydrus for Mild to Moderate Open Angle Glaucoma
The goal of the study is to prospectively evaluate and compare Hydrus microstent to the iStent Inject Wide in combination with cataract surgery in patients with mild to moderate open angle glaucoma.
- Trial name
- NCT05583591
- Testing
- Combined cataract surgery with Hydrus microstent, Combined cataract surgery with iStent Inject W
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Diablo Eye Associates
Hypertension
A Study to Investigate the Antihypertensive Efficacy of MK0954
After a 4 week placebo period, patients were randomized to Placebo or Losartan 50 mg arms, after 6 weeks non-responders were up titrated to 100 mg losartan for the remaining 6 weeks.
- Trial name
- NCT00887250
- Testing
- losartan potassium, Comparator: losartan
- Volunteers
- 366 people
- Sponsor
- Merck Sharp & Dohme LLC
Essential Arterial Hypertension
Efficacy and Safety of Candesartan Associated With Chlorthalidone in Essential Arterial Hypertension Control
The purpose of this study is to evaluate the non-inferiority clinical efficacy of two different drug associations in the essential hypertension control.
- Trial name
- NCT02521233
- Testing
- Candesartan + Chlorthalidone (8mg+12,5mg), Candesartan + Chlorthalidone (8 mg + 25 mg), losartan+hydrochlorothiazide
- Sponsor
- EMS
Hypertension, Mineralocorticoid Receptor Antagonist
The Effect of CS-3150 Exposure on Corrected QT (QTc) Interval Duration in Healthy Volunteers
This study will test if a study drug (CS-3150) will affect the heart rate in healthy males and females. Two doses of the study drug will be tested. Heart rate is not expected to be different between the study groups.
- Trial name
- NCT04019652
- Testing
- CS-3150, Moxifloxacin
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Daiichi Sankyo
Obesity, Diabetes Mellitus, Type 2
A Study of the Safety and Effectiveness of Topiramate on Insulin Sensitivity in Overweight or Obese Patients With Type 2 Diabetes
The purpose of this study is to investigate (1) the effect of topiramate on insulin sensitivity in overweight or obese patients with type 2 diabetes mellitus and (2) the safety of topiramate in type 2 diabetic patients.
- Conditions
- Obesity, Diabetes Mellitus, Type 2, Diabetes Mellitus, Adult-Onset
- Trial name
- NCT00236626
- Testing
- topiramate
- Volunteers
- 38 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Pulmonary Arterial Hypertension
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Assess Safety and Efficacy of Ambrisentan in Subjects With Pulmonary Arterial Hypertension.
A phase 3, randomized, double-blind, placebo-controlled study to assess safety and efficacy of ambrisentan in subjects with pulmonary arterial hypertension.
- Trial name
- NCT00423202
- Testing
- ambrisentan
- Volunteers
- 186 people
- Sponsor
- Gilead Sciences
Essential Hypertension, Sleep Quality
Sleep Hygiene Education and Blood Pressure Control in Essential Hypertension in Primary Care
This randomized controlled trial evaluated the effect of a brief sleep hygiene education program on sleep quality and blood pressure in adults with essential hypertension attending a family practice center in southern Türkiye.
- Conditions
- Essential Hypertension, Sleep Quality, Primary Care
- Trial name
- NCT07257237
- Testing
- Sleep hygiene education program
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people
- Sponsor
- Ozturk Gurer Tutu, MD
Glaucoma, Open-Angle, Ocular Hypertension
To Compare the Safety and Efficacy of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both Eyes
To compare the safety and efficacy of Perrigo's product to an FDA approved product in the treatment of Primary Open Angle Glaucoma or Ocular Hypertension in Both Eyes.
- Trial name
- NCT04024072
- Testing
- Brinzolamide 1% ophthalmic suspension, Azopt 1% Ophthalmic Suspension
- Where
- United States
- Volunteers
- 495 people
- Sponsor
- Padagis LLC
Multimorbidity, Hypertension
Development and Validation of a Comprehensive Management Service Package for Older Adults With Multimorbidity
This study aims to test a new comprehensive management service package for older adults with two or more chronic conditions (multimorbidity).
- Conditions
- Multimorbidity, Hypertension, Diabetes Mellitus, Coronary Artery Disease
- Trial name
- COMPASS (NCT07151430)
- Testing
- Service Package Group
- Volunteers
- 358 people
- Sponsor
- Xuanwu Hospital, Beijing
Resistant Hypertension, Controlled Hypertension
Prevalence, Clinical Characteristics and Treatment of Bulgarian Patients With Resistant Hypertension
Study objectives: Our study aimed to assess the prevalence, characteristics, and treatment of patients with resistant hypertension (HTN) in Bulgarian hypertensive population.
- Trial name
- NCT07877844
- Where
- Bulgaria
- Volunteers
- 256 people
- Sponsor
- Medical University of Sofia
Hypertension
Evaluating Control of Hypertension - Effect of Social Determinants
This study evaluates the impact of a large-scale, national expansion of Medicaid on hypertension incidence, screening, treatment, and management.
- Trial name
- ECHOES (NCT03545763)
- Testing
- Medicaid Expansion
- Where
- United States
- Volunteers
- 1,939,783 people
- Sponsor
- Oregon Health and Science University
Hypertension
A Study on the Long-term Efficacy of Nebivolol After Withdrawal of Therapy
This study will evaluate the long-term efficacy of nebivolol monotherapy in patients with stage 1 or stage 2 hypertension after the withdrawal of active medication.
- Trial name
- NCT00785512
- Testing
- Nebivolol
- Where
- 26 sites in United States
- Volunteers
- 207 people
- Sponsor
- Forest Laboratories
Hypertension
Evaluation of the Safety, Efficacy and Pharmacokinetics of MICARDIS® (Telmisartan) in Children and Adolescents With Hypertension
Study to assess the blood pressure lowering effects of two doses of telmisartan over a four-week treatment period; to determine potentially effective doses for pediatric patients for future studies; to assess the safety and…
- Trial name
- NCT02242344
- Testing
- Telmisartan
- Volunteers
- 77 people
- Sponsor
- Boehringer Ingelheim
Normal Tension Glaucoma
Evaluation of PHP-201 Ophthalmic Solution in Patients With Normal Tension Glaucoma
Evaluation of the optimal dose for the efficacy in reduction of intraocular pressure and safety of PHP-201 ophthalmic solution in patients with normal tension glaucoma
- Trial name
- NCT03106532
- Testing
- PHP-201 0.25% ophthalmic solution, PHP-201 0.5% ophthalmic solution
- Where
- South Korea
- Volunteers
- 119 people
- Sponsor
- pH Pharma
Primary Open Angle Glaucoma, Ocular Hypertension
A Study of Efficacy and Safety of PHP-201 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension
This is a phase 3 study to confirm the efficacy in reduction of intraocular pressure and safety of PHP-201 ophthalmic solution in patients with primary open-angle glaucoma or ocular hypertension.
- Trial name
- NCT04863365
- Testing
- PHP-201 ophthalmic solution
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- pH Pharma
Pulmonary Hypertension, COPD
SPHERIC-1. Sildenafil and Pulmonary HypERtension In COPD
Although pulmonary hypertension (PH) is a quite frequent complication of advanced pulmonary diseases, and it is an independent prognostic factor, until now no evidence-based treatment approach exists for those patients.
- Trial name
- SPHERIC-1 (NCT01441934)
- Testing
- Sildenafil citrate, Sugar pills
- Where
- 10 sites in Italy
- Volunteers
- 32 people
- Sponsor
- Italian Association of Hospital Pneumologists
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