Clinical trials: Controlled Hypertension
Diabetes, Hypertension
Take Charge of Your Diabetes
The investigator plans to assess enrollment rates among two different enrollment methods, while providing a behavioral economic intervention to enhance the uptake of home-health monitoring devices to lower hemoglobin A1C among…
- Trial name
- NCT01977495
- Testing
- Financial Incentive: Fixed Lottery
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- University of Pennsylvania
Essential Hypertension
To Evaluate the Safety and Efficacy of a Single-Use IVUS Ablation for Primary Hypertension
This is a prospective, multicenter, blinded, randomized controlled clinical trial designed to evaluate the safety and efficacy of a single-use intravascular ultrasound ablation catheter and ultrasound ablation system in the…
- Trial name
- NCT07051811
- Testing
- Intravascular Ultrasound Ablation Therapy, Renal Artery Angiography
- Where
- 18 sites in China
- Volunteers
- 213 people
- Sponsor
- Lepu Medical Technology (Beijing) Co., Ltd.
Chronic Kidney Disease, Diabetes Mellitus, Type 2
GLUcose Transport and REnalPROtection in Chronic Kidney Disease
This is a single-center, double blind, randomized, parallel-arms study designed to investigate the effects of a six-month treatment with the SGLT2i dapagliflozin on markers of kidney senescence, inflammation and…
- Conditions
- Chronic Kidney Disease, Diabetes Mellitus, Type 2, Hypertension
- Trial name
- GLUTREPRO (NCT05998837)
- Testing
- Dapagliflozin 10mg Tab
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
Eye Movement Desensitization and Reprocessing Intervention, Blood Pressure
The Effect of Eye Movement Desensitization and Reprocessing Intervention in Hypertension Patient.
Eye Movement Desensitization and Reprocessing intervention may improve anxiety, depression, systolic blood pressure and heart rate variability in patients with hypertension.
- Conditions
- Eye Movement Desensitization and Reprocessing Intervention, Blood Pressure, Heart Rate Variability, Anxiety
- Trial name
- EMDR (NCT05836181)
- Testing
- Eye Movement Desensitization and Reprocessing
- Where
- Taiwan
- Volunteers
- 110 people
- Sponsor
- Miao-Yi Chen
Prehypertension, Hypertension, Stage I
Effect of Ginseol Kg1 on Blood Pressure Lowering
In this study, we investigate the effects of Ginseol Kg1 (Korea red ginseng extract) on blood pressure in prehypertensive or stage I hypertensive patients.
- Trial name
- NCT01483430
- Testing
- Ginseol Kg1 (low dose), Ginseol Kg1(high dose)
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Hypertension, Asthma
A Collaborative Model to Improve Blood Pressure (BP) Control and Minimize Racial Disparities
The purpose of the study is to determine the degree to which pharmacist-physician collaborative management (PPCM) of hypertension can be adopted and implemented in clinics with geographic and racial diversity and whether patients…
- Trial name
- NCT00935077
- Testing
- PPCM Asthma, 24 Month PPCM BP, 9 Month PPCM BP
- Where
- 28 sites in United States
- Volunteers
- 1,441 people
- Sponsor
- University of Iowa
Systemic Vascular Resistance
Hemodynamic Changes and Vascular Tone Control After Bariatric Surgery
Obese patients have increased cardiovascular risk and target organ damage (TOD) as compared to people with normal weight. Weight loss reduces cardiovascular risk and TOD.
- Trial name
- NCT03115502
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Parc de Salut Mar
Primary Aldosteronism, Hypertension
Adrenal Artery Ablation Treats Primary Aldosteronism
Primary aldosteronism (PA) is one of the most common cause of endocrine and resistant hypertension. Current studies have shown that the activation of the renin-angiotensin-aldosterone system (RAAS) and the increased sympathetic…
- Trial name
- NCT03398785
- Testing
- Endovascular chemical Ablation of Adrenal Gland
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Third Military Medical University
Type 2 Diabetes Mellitus
Evaluation of the Fixed-dose Combination of Irbesartan/Atorvastatin in Type 2 Diabetic Patients Diagnosed With Hyperlipidemia and Hypertension
Primary Objective: To evaluate the effect of irbesartan/atorvastatin fixed-dose combination comparing to each irbesartan and atorvastatin on flow mediated dilation change in type 2 diabetic patients diagnosed with hyperlipidemia…
- Trial name
- NCT02842359
- Testing
- Irbesartan/atorvastatin fixed dose combination, Irbesartan SR47436, Atorvastatin
- Where
- South Korea
- Volunteers
- 11 people
- Sponsor
- Sanofi
Eisenmenger Syndrome, Pulmonary Arterial Hypertension of Congenital Heart Disease
A Study of Sotatercept for Patients With Eisenmenger Syndrome or Unrepaired Shunt-Associated Pulmonary Arterial Hypertension Resistant to Vasodilator Therapy
What is this study about? This study will test whether adding sotatercept to usual medicines for pulmonary arterial hypertension (PAH) can help adults who have PAH due to unrepaired congenital heart defects (atrial or ventricular…
- Trial name
- SuMILE (NCT07356778)
- Testing
- Sotatercept, vasodilator-based PAH therapy
- Where
- 10 sites in Japan
- Volunteers
- 36 people
- Sponsor
- Kazuya Hosokawa
Hypertension,
Educational Intervention for Sodium Restriction in Patients With Hypertension
This parallel, randomized clinical trial will include 120 participants. They will be allocated to a sodium restriction educational intervention or usual care groups.
- Trial name
- NCT02848690
- Testing
- Educational Intervention, Usual Care Intervention Group
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Hypertension
Study of a Comprehensive Intelligent Hypertension managEment SyStem
This cluster randomized controlled trial aims to evaluate the efficacy of a comprehensive intelligent hypertension management system (CHESS) in blood pressure lowering in primary health care (PHC) settings of China.
- Trial name
- CHESS (NCT05605418)
- Testing
- CHESS intervention
- Where
- China
- Volunteers
- 1,666 people
- Sponsor
- China National Center for Cardiovascular Diseases
Hypertension, Hyperlipidemia
Cardiovascular Lifestyle Study: Effects and Expense of a Cardiovascular Risk Reduction Clinic in Primary Care
The purpose of this trial is to study the effects on risk reduction and expense of 3 approaches to the care of people with cardiovascular risk factors in a naturalistic primary care environment.
- Conditions
- Hypertension, Hyperlipidemia, Hyperglycemia, Cardiovascular Disease
- Trial name
- NCT00291824
- Testing
- Cardiovascular risk factors and willingness to change
- Where
- Canada
- Volunteers
- 670 people
- Sponsor
- Caroline Medical Group
Hypertension
Efficacy and Safety of Azilsartan Medoxomil in African American Participants With Essential Hypertension
The purpose of this study is to evaluate the effectiveness and safety of azilsartan medoxomil compared to placebo, once daily (QD), in African-American participants with essential hypertension.
- Trial name
- NCT00591253
- Testing
- Azilsartan medoxomil
- Where
- 64 sites in United States, Puerto Rico
- Volunteers
- 413 people
- Sponsor
- Takeda
Hypertension, Type 2 Diabetes Mellitus
Amiloride for Resistant Hypertension
To evaluate the antihypertensive effect of amiloride added to triple antihypertensive therapy in patients with resistant hypertension (RH) and type 2 diabetes mellitus (T2DM)
- Conditions
- Hypertension, Type 2 Diabetes Mellitus, Microalbuminuria
- Trial name
- NCT02122731
- Testing
- Amiloride
- Where
- 4 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- Ib Abildgaard Jacobsen
Idiopathic Pulmonary Arterial Hypertension
Virtual Reality in Patients With Pulmonary Hypertension: A Randomized Controlled Trial
The goal of this research is to investigate the effectiveness of exercise administered via immersive virtual reality in patients with pulmonary hypertension, thereby contributing to the existing literature on this subject.
- Trial name
- NCT07558460
- Testing
- Virtual Reality Group
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Istanbul University - Cerrahpasa
Glaucoma
Impact of an Educational Video on Satisfaction After Glaucoma Surgery
Overall Objective: This study will assess whether an educational video is effective in increasing patient satisfaction with glaucoma surgery. 1.
- Trial name
- NCT03958929
- Testing
- Educational Video
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Sun Yat-sen University
Hypertension
Nebivolol in Patients With Systolic Stage 2 Hypertension
The primary object of this study is to evaluate the efficacy and safety of 6 weeks of nebivolol monotherapy compared with placebo in patients with systolic stage 2 hypertension.
- Trial name
- NEB-MD-20 (NCT01057251)
- Testing
- Nebivolol
- Where
- 36 sites in United States
- Volunteers
- 433 people
- Sponsor
- Forest Laboratories
Primary Open Angle Glaucoma (POAG), Ocular Hypertension (OH)
A Study to Evaluate Efficacy and Safety of YSBP Compared to Lumigan in Patients With Glaucoma or Ocular Hypertension
This study is to establish non-inferiority of a preservative free formulation of Bimatoprost ophthalmic solution 0.01% (YSBP) of YS Life Science Co., Ltd.
- Trial name
- NCT07661329
- Testing
- Bimatoprost ophthalmic solution 0.01% YSBP, bimatoprost ophthalmic solution 0.01% (Lumigan®)
- Where
- 22 sites in United States, India
- Volunteers
- 600 people
- Sponsor
- YS Life Science Co., Ltd.
Hypertension, Diabete Type 2
Comorbidity-Oriented Primary Care and Integrated Management for Hypertension and Diabetes Mellitus
The COMPACT-HTDM study is a parallel, two-arm cluster randomized controlled trial designed to evaluate a comorbidity-oriented integrated primary care management model for elderly patients with coexisting hypertension and type 2…
- Conditions
- Hypertension, Diabete Type 2, Comorbidities and Coexisting Conditions
- Trial name
- COMPACT-HTDM (NCT07528391)
- Testing
- Integrated Comorbidity Management Package, Usual Care intervention
- Volunteers
- 960 people
- Sponsor
- Nanchang University
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