Clinical trials: Controlled Hypertension
Hypertension, Obstructive Sleep Apnea
Effect of Antihypertensive Agents Over Sleep Apnea
Obstructive sleep apnea and hypertension are well-known cardiovascular risk factors. Their control could reduce the burden of heart disease across populations.
- Trial name
- NCT01896661
- Testing
- Diuretics, Calcium Channel Blockers
- Where
- Brazil
- Volunteers
- 53 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Diabetes, Diabetes Mellitus
Computer-Assisted Cancer Risk Behavior Counseling
To test whether or not giving patients information before their doctor visits changes the care they receive and what type of information is best to give before the doctor visit.
- Conditions
- Diabetes, Diabetes Mellitus, Hypertension
- Trial name
- NCT00242645
- Testing
- Health Information, Preventive Services, Computer tailored information
- Volunteers
- 200 people
- Sponsor
- Thomas Jefferson University
Pulmonary Arterial Hypertension
Phase III Clinical Worsening Study of UT-15C in Subjects With PAH Receiving Background Oral Monotherapy
This is an international, multicenter, randomized, double-blind, placebo-controlled, event driven study in subjects with pulmonary arterial hypertension.
- Trial name
- FREEDOM-EV (NCT01560624)
- Testing
- Treprostinil Diolamine
- Where
- 155 sites in United States, Argentina and 21 more
- Volunteers
- 690 people
- Sponsor
- United Therapeutics
Ocular Hypertension
An Open-Label Study of an Ophthalmic Solution to Reduce Intraocular Pressure in Patients With Ocular Hypertension
The purpose of this study is to determine the safety and tolerability of topical C-KAD Ophthalmic Solution in reducing intraocular pressure in patients with ocular hypertension.
- Trial name
- NCT00825396
- Testing
- C-KAD Ophthalmic Solution
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Chakshu Research, Inc.
Severe Preeclampsia
Furosemide vs Placebo in Severe Preeclampsia Postpartum
This randomized, double-blind, placebo-controlled trial evaluates whether oral furosemide 40 mg, initiated 12 hours postpartum, reduces hospital length of stay compared to placebo (folic acid 5 mg) in postpartum women with severe…
- Trial name
- FUROPE (NCT07648251)
- Testing
- Furosemide, Folic Acid 5 MG
- Where
- Honduras
- Volunteers
- 186 people
- Sponsor
- Universidad Nacional Autonoma de Honduras
Hypertension
Efficiency of Monitoring and Control Program of Hypertension Through Pharmacy Offices. APOF Project
Background: Hypertension in adults is the factor most prevalent cardiovascular risk and motivates further inquiries, generating a very high cost of medical care.
- Trial name
- APOF (NCT02032472)
- Testing
- Measurement of Arterial Pressure
- Where
- Spain
- Volunteers
- 677 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Hypertension, Blood Pressure
A Registry Study on the "Action of Controlling Ambulatory Blood Pressure to Target in Ten Thousand Patients"
24 hour ambulatory blood pressure (ABP) monitoring should be the first choice for diagnosis and treatment of hypertension according to European Societyof Hypertension (ESH) and the European Society of Cardiology (ESC) guideline…
- Conditions
- Hypertension, Blood Pressure, Cardiovascular Diseases
- Trial name
- NCT03547856
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Yan Li
Uncontrolled Hypertension
A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
The purpose of this clinical trial is to measure the safety and efficacy of RTN-001 in adult participants with uncontrolled hypertension versus placebo.
- Trial name
- NCT07142356
- Testing
- RTN-001
- Where
- 34 sites in United States
- Volunteers
- 280 people
- Sponsor
- Retension Pharmaceuticals. Inc.
Hypercholesterolemia, Hypertension
Effectiveness of Nigella Sativa (Kalonji) Seed in Dyslipidemia
This is a pilot study. The aim of the investigators' study is to evaluate the effectiveness of nigella sativa seed in the treatment of dyslipidemia.
- Conditions
- Hypercholesterolemia, Hypertension, Diabetes Mellitus, Metabolic Syndrome X
- Trial name
- NCT00327054
- Testing
- Nigella sativa seed
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Primary Open-Angle Glaucoma (POAG)
Efficacy and Safety of Different Dosages of Mexidol® in Patients With Primary Open-angle Glaucoma (POAG)
The present trial is planned to investigate and identify the best dosage of investigational drugs with respect to the treatment of open-angle glaucoma.
- Trial name
- NCT06903156
- Testing
- Mexidol
- Where
- 7 sites in Russia
- Volunteers
- 102 people
- Sponsor
- Pharmasoft
Liver Transplant With Clinically Significant Portal Hypertension
Evaluation of Efficacy and Safety of Somatostatin Used as Inflow Modulator in Liver Transplantation.
This study is a 5 day, single-center, randomized, double blind, placebo-controlled study to evaluate the efficacy and safety of Somatostatin used as inflow modulator in liver transplantation.
- Trial name
- NCT01290172
- Testing
- Administration of Somatostatin
- Where
- Belgium
- Volunteers
- 33 people
- Sponsor
- University Hospital, Ghent
Respiratory Control in Premature Infants
Prematurity-Related Ventilatory Control
The purpose of this research study is to improve our understanding of unstable breathing and heart blood flow patterns seen in premature infants.
- Trial name
- PreVent (NCT03464396)
- Testing
- Bedside Physiology study, Carotid Body Function Test, Room Air Challenge
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- Washington University School of Medicine
Pregnancy, Gestational Diabetes Mellitus (GDM)
Polyphenol Intake, Mediterranean Diet Adherence, and Oxidative Stress in Pregnancy
This study is a randomized controlled clinical trial designed to evaluate the effect of a polyphenol-rich dietary intervention during pregnancy on endothelial function, oxidative stress biomarkers, and maternal and neonatal…
- Conditions
- Pregnancy, Gestational Diabetes Mellitus (GDM), Preeclampsia, Hypertension, Pregnancy-Induced
- Trial name
- PREGPOLY (NCT07656532)
- Testing
- Natural Non-Alkalized Cocoa, Polyphenol-Rich Dietary Counseling
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Hypertension
Italian Study on the Cardiovascular Effects of Systolic Blood Pressure Control - CARDIOSIS Study
Multicenter, prospective, randomised, open study comparing the effect of the following two strategies in hypertensive subjects > 55 years and poorly controlled (systolic blood pressure >= 150 mmHg) by antihypertensive treatment…
- Trial name
- NCT00421863
- Testing
- Triatec 10 mg, Triatec HCT 5, Lasix 25
- Where
- 45 sites in Italy
- Volunteers
- 1,111 people
- Sponsor
- Heart Care Foundation
Hypertension
Treating Hypertension With Breath Control
The purpose of this study is to determine if blood pressure can be reduced in hypertensive subjects by regularising and slowing their breathing. This may be a safe and affordable complementary treatment for hypertension.
- Trial name
- NCT01285193
- Testing
- Breath control
- Where
- Malaysia
- Volunteers
- 84 people
- Sponsor
- Penang Hospital, Malaysia
Intra Cerebral Hemorrhage, Hypertension
Proper Timing of Control of Hypertension and Outcome in Acute Spontaneous Intracerebral Hemorrhage.
The ideal management of blood pressure in BP after acute intracerebral haemorrhage is still debated and whether a higher intensive reduction of blood pressure after acute intracerebral haemorrhage may be better or not is still…
- Trial name
- NCT04167644
- Testing
- Modified Rankin Scale (mRS)
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Mansoura University Hospital
Hypertension
Blood Pressure-Improving Control Among Alaska Native People" (BP-ICAN)
"Blood Pressure: Improving Control among Alaska Native People" (BP-ICAN) that targets blood pressure control among Alaska Native and American Indian (AN/AI) people diagnosed with hypertension.
- Trial name
- CHAR2 (NCT03872856)
- Testing
- BP-ICAN
- Where
- 2 sites in United States
- Volunteers
- 164 people
- Sponsor
- Southcentral Foundation
Hypertension
A Study to Assess the Safety, Tolerability, and Efficacy of Monthly Subcutaneous Administration of ION904 in Participants With Uncontrolled Hypertension
The purpose of this study is to evaluate the effect of ION904 on plasma angiotensinogen (AGT) in participants with uncontrolled hypertension.
- Trial name
- NCT05314439
- Testing
- ION904
- Where
- 8 sites in United States
- Volunteers
- 48 people
- Sponsor
- Ionis Pharmaceuticals, Inc.
Sleep Apnea Syndrome
Cardiovascular Consequences of Intermittent Hypoxia in Healthy Subjects
The study is a prospective field evaluation to assess the effects of the chronic Intermittent Hypoxia exposure in 12 healthy humans.
- Trial name
- NCT00746928
- Testing
- Chronic Intermittent Hypoxia
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Open-angle Glaucoma
Open-angle Glaucoma Subjects on One Ocular Hypotensive Medication Randomized to Treatment With Two Trabecular Micro-bypass Stents or Selective Laser Trabeculoplasty
Evaluation of intraocular pressure (IOP) lowering effect of two iStent stents versus a SLT procedure in subjects with open-angle glaucoma on one ocular hypotensive medication.
- Trial name
- NCT01444105
- Testing
- iStent, SLT
- Where
- Armenia
- Volunteers
- 80 people
- Sponsor
- Glaukos Corporation