Clinical trials: Controlled Hypertension
Infections, Heart Failure
Rural Hospital-Level Care at Home for Acutely Ill Adults
This study examines the implications of providing hospital-level care in rural homes.
- Conditions
- Infections, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT05256303
- Testing
- Home Hospital care, Traditional Hospital care
- Where
- 3 sites in United States, Canada
- Volunteers
- 160 people
- Sponsor
- Brigham and Women's Hospital
Hepatocellular Carcinoma With CSPH
Surgical Resection Versus Percutaneous Local Ablative Therapy for Hepatocellular Carcinoma
The aim of this study is to compare the operative complication and short-/long-term therapeutic effects of percutaneous local ablative therapy (PLAT) versus surgical resection(SR) on small hepatocellular carcinoma(HCC) patients…
- Trial name
- NCT01860222
- Testing
- SR, PLAT
- Where
- 2 sites in China
- Volunteers
- 160 people
- Sponsor
- Eastern Hepatobiliary Surgery Hospital
Idiopathic Intracranial Hypertension
An RCT of Bariatric Surgery vs a Community Weight Loss Programme for the Sustained Treatment of IIH
Idiopathic intracranial hypertension (IIH) is a condition with an unknown cause or causes. The condition is associated with raised pressure in the brain and can cause disabling daily headaches and loss of sight, which can be…
- Trial name
- IIH:WT (NCT02124486)
- Testing
- Bariatric surgery, Dietetic intervention
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Glaucoma
Endothelial Cell Loss in Pseudophakic Patients Receiving a Paul Glaucoma Drainage Device With Its Tube Inserted in the Anterior Versus Posterior Chamber: a Randomized Controlled Trial
Rationale: Glaucoma is a group of diseases characterized by progressive neuropathy of the optic nerve associated with visual field loss.
- Trial name
- NCT05500469
- Testing
- Paul glaucoma drainage device (GDD)
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Oogziekenhuis Rotterdam
Pregnancy Induced Hypertension (PIH)
Randomized Controlled Study to Compare Efficacy of Aspirin 75mg and 150mg In the Prevention of Preeclampsia In High Risk Pregnant Women
Preeclampsia in pregnancy is a dreaded complication which has both fetal and maternal adverse outcomes. Studies and WHO have advocated that this complication can be prevented by Aspirin.
- Trial name
- NCT07373756
- Testing
- Aspirin
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Dr. Sunita Pun
Arterial Hypertension, Metabolic Syndrome
Blood Pressure Control and Compliance to Treatment in Hypertensive Patients With Metabolic Syndrome: a Study Based on Home Blood Pressure Telemonitoring and Assessment of Psychological Determinants
The purpose of this study is to assess whether, in patients at high cardiovascular risk (hypertension with metabolic syndrome), long-term (1-year) blood pressure control is most effective when based on home blood pressure…
- Trial name
- TELEBPMET (NCT01541566)
- Where
- 12 sites in Italy
- Volunteers
- 254 people
- Sponsor
- Italian Institute of Telemedicine
HELLP Syndrome
Study of Prognostic Values of Platelet Indices and Inflammatory Markers in Patients With HELLP Syndrome.
This study aims to evaluate the prognostic values of platelet indices and inflammatory markers in patients with HELLP syndrome as:- :-Primary outcome To investigate prognostic values of platelet indices and. .
- Trial name
- NCT07377786
- Testing
- Group I: 30 patients with HELLP syndrome
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Diabetes, Hypertension
Impact of Intermittent Fasting and Mediterranean Diet on the Physical Health of the Elderly
The prevalence of chronic diseases is increasing globally. In recent years, intermittent fasting has emerged as an effective dietary pattern against some of the most common chronic diseases in the elderly, alongside the…
- Conditions
- Diabetes, Hypertension, Dyslipidemias, Obesity
- Trial name
- FASTMED (NCT06480669)
- Testing
- Time Restricted Feeding, Mediterranean Diet
- Where
- Spain
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Esophageal Varices, Bleeding
Self-expandable Esophageal Stent Versus Balloon Tamponade in Refractory Esophageal Variceal Bleeding.
In the last years, important advances have been done in the treatment and prevention of esophageal variceal bleeding. Experts agree that the combination of pharmacological and endoscopic therapy should be the first line therapy…
- Conditions
- Esophageal Varices, Bleeding, Cirrhosis
- Trial name
- NCT01242280
- Testing
- Stent, Tamponade
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- Hospital Clinic of Barcelona
Hypertension, Obesity
Renal Response to Lower Body Negative Pressure in Pre-hypertensive States
The purpose of this study is to determine whether in pre-hypertensive and hypertensive states such as white coat hypertension, obesity related hypertension or resistant hypertension, renal function is more sensitive to…
- Conditions
- Hypertension, Obesity, White Coat Hypertension, Resistant Hypertension
- Trial name
- NCT01734096
- Testing
- Lower body negative pressure (LBNP), Candesartan cilexetil
- Where
- 2 sites in Switzerland
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- PD Dr. Grégoire Wuerzner
Primary Aldosteronism, Hypertension
Comparing the Efficacy and Safety of Finerenone and Spironolactone in the Treatment of Primary Aldosteronism
Primary aldosteronism (PA) is thought to be the most common secondary endocrine form of hypertension. Compared with patients with essential hypertension with similar blood pressure, patients with PA have significantly higher…
- Trial name
- NCT05814770
- Testing
- Finerenone, Spironolactone
- Volunteers
- 96 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Hypertension, Renal Denervation Therapy
Efficacy and Safety of Renal Denervation on Isolated Diastolic Hypertension
This study aims to evaluate the efficacy and safety of renal denervation (RDN) in patients with isolated diastolic hypertension (IDH).
- Trial name
- NCT06783296
- Testing
- Renal Denervation, Renal Angiography
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Shanghai 10th People's Hospital
Intervention, Control Group
"Health in Mobile" for Community-dwelling Individuals With Chronic Diseases
This study aims to provide a mobile-apps-based intervention to facilitate individuals with chronic diseases such as high blood pressure and diabetes to adopt healthy behaviours.
- Trial name
- NCT05949320
- Testing
- e-Motivational Interviewing
- Where
- 3 sites in Hong Kong
- Volunteers
- 461 people
- Sponsor
- Education University of Hong Kong
Hypertension, Blood Pressure
Check and Support -Enhancing the Treatment of Hypertension in Outpatient Care, a Multicenter Study
The purpose of this pragmatic multi-centre, cluster randomized controlled trial is to test the effectiveness of tailored SMS-text message support combined with an information-motivation-behavioral skills (IMB) model-based…
- Conditions
- Hypertension, Blood Pressure, Patient Compliance, Patient Adherence
- Trial name
- NCT02377960
- Testing
- IMB model-based initiation of antihypertensive medication, Tailored SMS-text message support, Usual care
- Where
- 6 sites in Finland
- Volunteers
- 119 people
- Sponsor
- Kuopio University Hospital
Obstructive Sleep Apnea Syndrome, Hypertension
Combination Therapy Associating CPAP and Mandibular Advancement Device in OSA
The aim of this study is to evaluate the efficacy of a combination of Continuous Positive Airway Pressure (CPAP) and a Mandibular Advancement Device (MAD) on nocturnal Blood Pressure control in hypertensive patients in…
- Trial name
- PPC-OAM (NCT04021810)
- Testing
- Continuous Positive Airway Pressure (CPAP) and patient education, Mandibular Advancement Device
- Where
- 4 sites in France
- Volunteers
- 5 people
- Sponsor
- University Hospital, Grenoble
Chronic Kidney Diseases, Hypertension
Nephrospec Switzerland
This is a randomized, double-blind sham-controlled monocentric trial. 30 patients that are diagnosed with hypertension and with moderate to severe chronic kidney disease are included in this trial.
- Trial name
- NCT06194591
- Testing
- NephrospecTM, low-intensity extracorporal shockwave therapy device
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Menno Pruijm
Hypertension
Treatment of Hypertension: an Interventional Approach to Improve Blood Pressure Control
The purpose of the study is to access the change in mean daytime systolic blood pressure in participants with essential hypertension not adequately controlled (defined as mean systolic daytime ambulatory blood pressure ≥ 135…
- Trial name
- DRIVE (NCT02362893)
- Testing
- Direct Observed Therapy
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
CSF Leak, CSF Pressure Increased
Conservative vs Interventional Management of Postsurgical CSF Pseudomeningocele
Dear Sir or Madam, You have been invited to participate in a clinical study whose aim is to compare the effectiveness of two different approaches to the treatment of cerebrospinal fluid (CSF) pseudomeningocele - conservative…
- Conditions
- CSF Leak, CSF Pressure Increased, CSF Circulation Disorder, Puncture
- Trial name
- PSEUDO (NCT07614399)
- Testing
- Lumbar Drainage, Pseudomeningocele Puncture, Puncture with Fibrin Glue Application
- Where
- Czechia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Systemic Scleroderma, Pulmonary Hypertension
Placebo Controlled Trial of Bosentan in Scleroderma Patients
The purpose of this study is to determine whether the drug Bosentan improves exercise tolerance in scleroderma patients.
- Trial name
- NCT00377455
- Testing
- Bosentan
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Georgetown University
Hypertension
An Comparative Pharmacokinetic Study of Amlodipine Besylate Controlled-release Tablets,China in Normal, Healthy, Adult, Human Subjects Under Fasting Conditions
Amlodipine Besylate Controlled-release Tablets in Healthy Volunteers in a Randomized, Open, Two-cycle, Double-cross, Fasting State Comparative Pharmacokinetic Study.
- Trial name
- NCT05667818
- Testing
- Amlodipine besylate tablets (trade name: Norfloxacin ®）, Amlodipine besylate controlled-release tablets
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Overseas Pharmaceuticals, Ltd.
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