Clinical trials: Controlled Hypertension
End Stage Liver DIsease, Portal Hypertension
Somatostatin in Living Donor Liver Transplantation
Aim of the study is to investigate the safety and the efficacy of somatostatin as liver inflow modulator in patients with end-stage liver disease (ESLD) and clinically significant portal hypertension (CSPH) undergoing…
- Trial name
- NCT04107428
- Testing
- Somatostatin
- Volunteers
- 56 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Hypertension, Patient Compliance
To Achieve Blood Pressure Control With Retained Quality of Life
The purpose of the study is to get an understanding about what problems patients with hypertension are facing, how they manage these challenges, how they feel and what requirements they believe are important to have in their…
- Trial name
- NCT02682095
- Where
- Sweden
- Volunteers
- 12 people
- Sponsor
- Eva Drevenhorn
Metabolic Cardiovascular Syndrome
Home Bicycle Exercise and Aerobic Capacity
The subjects with MetS or type 2 diabetes were enrolled for this exercise-training program. All participators underwent an indoor bicycle exercise for twelve weeks.
- Trial name
- NCT02268292
- Testing
- bicycle exercise
- Volunteers
- 37 people
- Sponsor
- Taichung Veterans General Hospital
Ischemic Stroke, Transient Ischemic Attack
European Blood Pressure Intensive Control After Stroke
Stroke is the third most common cause of death worldwide and the leading cause of disability. High blood pressure is an important risk factor for stroke.
- Trial name
- EPICS-Pilot (NCT04647292)
- Testing
- anti-hypertensive, home blood pressure measurement, telemonitoring and medication titration, Standard of Care Blood Pressure Management with Antihypertensives
- Where
- Ireland
- Volunteers
- 142 people
- Sponsor
- University College Dublin
Glaucoma, Ocular Hypertension
Tolerability, Safety and Efficacy of RKI983 Eye Drops in Subjects With Primary Open Angle Glaucoma and Ocular Hypertension
This study will evaluate the tolerability and safety of RKI983 ophthalmic solution and explore the effect of the compound on intraocular pressure in subjects with ocular hypertension.
- Trial name
- NCT00515424
- Testing
- RKI983
- Where
- 5 sites in United States
- Volunteers
- 90 people
- Sponsor
- Novartis
Glaucoma
Additive Intra-ocular Pressure Reduction Effect of Fixed Combination of Maleate Timolol 0.5%/Dorzolamide 2% on Monotherapy With Latanoprost in Patients With Elevated Intra-ocular Pressure
The purpose of this study is to evaluate the additive effect of dorzolamide/timolol fixed combination in patients undergoing monotherapy with latanoprost.
- Trial name
- NCT00906594
- Testing
- latanoprost
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- University of Sao Paulo
Lifestyle Intervention, Lifestyle Modification
Effect of Counselling Using Lifestyle Medicine Assessment Tool on Hypertensive Patients
The goal of this clinical trial is to learn if knowing and understanding a patient's daily habits and then giving clear advice on what changes to make can help control blood pressure better than the routine way of advising people…
- Conditions
- Lifestyle Intervention, Lifestyle Modification, Hypertension, Counselling
- Trial name
- NCT07449962
- Testing
- Lifestyle Intervention
- Where
- Pakistan
- Volunteers
- 126 people
- Sponsor
- Indus Hospital and Health Network
Hypertension, Pregnancy-Induced, Pre-Eclampsia
Early Vascular Adjustments During Hypertensive Pregnancy
Paradoxical fetal and maternal results of studies have led to inconsistent use of antihypertensive drugs or no treatment at all in mild to moderate gestational hypertension in the Netherlands.
- Trial name
- EVA (NCT02531490)
- Testing
- Labetalol, Nifedipine, Methyldopa
- Where
- Netherlands
- Volunteers
- 368 people
- Sponsor
- Maastricht University Medical Center
Hypertension
A Clinical Trial to Evaluate Efficacy, Tolerability, and Pharmacokinetic-Pharmacodynamic Relationship of Fimasartan/Hydrochlorothiazide
A 2-Week, Randomized, Double-Blind, Parallel, Placebo-Controlled Study to Evaluate the Efficacy, Tolerability, and Pharmacokinetic-Pharmacodynamic Relationship of Fimasartan in Combination with Hydrochlorothiazide in Patients…
- Trial name
- NCT02222480
- Testing
- Fimasartan, Hydrochlorothiazide
- Where
- South Korea
- Volunteers
- 103 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
High Blood Pressure (Hypertension).
Factorial Study of Metoprolol Succinate TOPROL-XL (324A)
The purpose of this research study is to determine if treatment with the combination of metoprolol succinate and hydrochlorothiazide is more effective at lowering blood pressure than treatment with either of the two drugs alone.
- Trial name
- NCT00642096
- Testing
- Metoprolol Succinate, Hydrochlorothiazide
- Volunteers
- 1,900 people
- Sponsor
- AstraZeneca
Hypertension
A Clinical Study to Compare Long-term Efficacy and Safety of an Aliskiren Based Regimen to a Hydrochlorothiazidebased Treatment Regimen With Optional Addition of Amlodipine
This study is designed to compare the long-term efficacy and safety of an aliskiren based regimen to an HCTZ based treatment regimen with optional addition of amlodipine in patients with essential hypertension.
- Trial name
- NCT00219154
- Testing
- aliskiren
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 1,125 people
- Sponsor
- Novartis
Hypertension
The Effect of Orally Administrated Nitrate on Renal Parameters and Systemic Haemodynamics
Treatment with nitrate has shown to lower blood pressure in both healthy subjects and hypertensive patients.Beside this nitrate have also shown to decrease arterial stiffness and improve endothelial function.But the effect of…
- Trial name
- APNI (NCT04755400)
- Testing
- isotonic saline 9%, Potassium nitrate, Potassium chloride
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Frank Mose
Obstructive Sleep Apnea
Targeted CPAP Therapy for Obstructive Sleep Apnea in Pregnancy
Prospective, randomized controlled trial. Pregnant women in early pregnancy will be randomized to either the Sleep Study + CPAP (Continuous Positive Airway Pressure Therapy) group or to a Standard Prenatal Care group.
- Trial name
- NCT02755831
- Testing
- CPAP, Pre-natal care
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Advanced Chronic Liver Disease, NASH
Non-invasive Evaluation of Portal Hypertension in Patients With Compensated Advanced Chronic Liver Disease by Assessment of Spleen Stiffness Using VCTE by FibroScan.
Hypothesis: The severity of portal hypertension in compensated advanced chronic liver disease (cACLD) can be assessed using vibration controlled transient elastography (VCTE) via the FibroScan® 502 Touch by measuring SS (splenic…
- Trial name
- NCT03778411
- Testing
- VCTE with splenic stiffness measurement
- Where
- United States
- Volunteers
- 298 people
- Sponsor
- Indiana University
Hypertension, High Blood Pressure
Uptake of Task-Strengthening for Blood Pressure Control
Uptake of a community-based evidence-supported interventions for hypertension control in Ghana are urgently needed to address the cardiovascular disease epidemic and resulting illness, deaths, and societal costs.
- Conditions
- Hypertension, High Blood Pressure, Cardiovascular Diseases
- Trial name
- NCT03490695
- Testing
- Practice Facilitation, Usual Care
- Where
- Ghana
- Volunteers
- 700 people
- Sponsor
- Kintampo Health Research Centre, Ghana
Pulmonary Hypertension
Safety of SonoVue on Pulmonary Hemodynamics
This is an intra-subject crossover comparative safety study to evaluate the effect of intravenous (IV) bolus injection of SonoVue on pulmonary hemodynamics.
- Trial name
- NCT01306292
- Testing
- SonoVue
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Bracco Diagnostics, Inc
Artificial Intelligence (AI), Artificial Intelligence (AI) in Diagnosis
A Deep-Learning-Enabled Electrocardiogram for Detecting Pulmonary Hypertension
This study aims to validate the use of an artificial intelligence-enabled electrocardiogram (AI-ECG) to screen for elevated PAP.
- Conditions
- Artificial Intelligence (AI), Artificial Intelligence (AI) in Diagnosis, Hypertension, Pulmonary
- Trial name
- ADDPH (NCT07079592)
- Testing
- AI-ECG Guidance
- Where
- Taiwan
- Volunteers
- 8,666 people
- Sponsor
- National Defense Medical Center, Taiwan
Preeclampsia
Assessing the Usability and Clinical Utility of the Congo Red Dot Test: A Case-control Study
A case-control study will evaluate the clinical utility of the Congo Red test GV-005 in following women with a clinical diagnosis of preeclampsia and clinically healthy women in the postpartum period
- Trial name
- NCT02610972
- Testing
- Congo Red test GV-005
- Where
- 2 sites in Bangladesh, Mexico
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Left Ventricular Hypertrophy, High Blood Pressure
Stress Reduction in the Prevention of Left Ventricular Hypertrophy
This study evaluated the effect of stress reduction by Transcendental Meditation (TM) on left ventricular mass compared to a health education control group in pre-hypertensive or hypertensive African-American adults over a…
- Trial name
- NCT05373732
- Testing
- meditation, Health education control
- Volunteers
- 171 people
- Sponsor
- Maharishi International University
Hypertension
Nutritional Strategy for Blood Pressure Control in Patients With Hypertension (NUPRESS)
Adherence to a healthy dietary pattern is part of the self-care of patients with hypertension, and may contribute substantially to therapeutic target goals as well as to a better quality of life.
- Trial name
- NCT03793881
- Testing
- Nutritional Strategy, Dietary Prescription
- Where
- 8 sites in Brazil
- Volunteers
- 408 people
- Sponsor
- Hospital do Coracao
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