Clinical trials: Controlled Hypertension
Hypertension
MBSR on Nocturnal Hypertension
Objectives: To examine the feasibility and acceptability of treating nocturnal hypertension by mindfulness-based stress reduction program (MBSR).
- Trial name
- NCT06510907
- Testing
- mindfulness based stress reduction program
- Where
- Hong Kong
- Volunteers
- 76 people
- Sponsor
- Chinese University of Hong Kong
Hypertension, Metabolic Syndrome
Jiangzhuo Qinggan Prescription and Irbesartan in the Treatment of Essential Hypertension(Hepatogastric Damp-heat)Clinical Study
Jangzhuo Qinggan prescription and irbesartan in the treatment of essential hypertension(Hepatogastric Damp-heat), randomized, parallel-controlled, multi-center clinical study.
- Trial name
- JZQG (NCT01082835)
- Where
- 5 sites in China
- Volunteers
- 240 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Glaucoma, Ocular Hypertension
A Single Centre Study to Evaluate 3 Ophthalmic Formulations in Healthy Subjects
A Single Centre, Placebo-Controlled, Double-Masked, Sequential Designed Study to Evaluate 3 Ophthalmic Formulations of AMA0076 in Healthy Subjects
- Conditions
- Glaucoma, Ocular Hypertension, Eye Disease
- Trial name
- NCT02003547
- Testing
- AMA0076
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Amakem, NV
Glaucoma
Effects of Balance Training in Individuals With Glaucoma
Glaucoma is a chronic progressive eye disease characterized by visual field loss, which may adversely affect postural control, functional mobility, and increase the risk and fear of falling.
- Trial name
- NCT07910955
- Testing
- Balance Training Program
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Hypertension
Evaluation of the Effect of Telmisartan on Blood Pressure Control of High Risk Patients
The study is designed to evaluate the effect of treatment with Micardis/MicardisPlus on blood pressure and its ability to reduce different indicated cardiovascular risk scores.
- Trial name
- NCT01108809
- Testing
- Telmisartan or Telmisartan and Hydrochlorthiazide
- Where
- 49 sites in Romania
- Volunteers
- 295 people
- Sponsor
- Boehringer Ingelheim
Hypertension
Study to Evaluate Safety and Tolerability, Pharmacodynamic Effects and Exploratory Efficacy of a Vaccine Against Essential Hypertension
CYT006-AngQb is a vaccine that induces a B-cell mediated immune response characterized by the generation of specific antibodies (IgG and IgM) against Angiotensin II. The vaccine is administered by subcutaneous injection.
- Trial name
- NCT00701649
- Testing
- CYT006-AngQb
- Where
- 6 sites in Germany, Switzerland
- Volunteers
- 60 people
- Sponsor
- Cytos Biotechnology AG
Blood Pressure, Hypertension
Effect of Dietary Salt Reduction on Blood Pressure in Kidney Transplant Recipients
Cardiovascular morbidity and mortality is increased in kidney transplant patients. High blood pressure (BP) contributes significantly to this risk and is also associated with shortened allograft survival.
- Conditions
- Blood Pressure, Hypertension, Kidney Transplant; Complications, Dietary Modification
- Trial name
- NCT03373500
- Testing
- Dietary salt reduction
- Where
- United Kingdom
- Volunteers
- 66 people
- Sponsor
- Epsom and St Helier University Hospitals NHS Trust
Scleroderma, Diffuse, Scleroderma, Systemic
Oral Ifetroban to Treat Diffuse Cutaneous Systemic Sclerosis (SSc) or SSc-associated Pulmonary Arterial Hypertension
The purpose of this phase 2 multicenter, randomized, double-blind, placebo-controlled, study is to assess the safety and efficacy of ifetroban in patients with diffuse cutaneous systemic SSc (dcSSc) or SSc-associated pulmonary…
- Conditions
- Scleroderma, Diffuse, Scleroderma, Systemic, Scleroderma, Limited, Sclerosis, Progressive Systemic
- Trial name
- NCT02682511
- Testing
- Oral Ifetroban
- Where
- 13 sites in United States, India
- Volunteers
- 34 people
- Sponsor
- Cumberland Pharmaceuticals
Intra-abdominal Hypertension, Acute Respiratory Distress Syndrome (ARDS)
End-expiratory Transpulmonary Pressure-guided vs Electrical Impedance Tomography-guided PEEP Titration Methods in Patients With Intra-abdominal Hypertension Combined With Acute Respiratory Distress Syndrome: a Randomized Crossover Controlled Study
This study aims to adopt a randomized crossover design to compare the effects of end-expiratory transpulmonary pressure-guided PEEP titration and EIT-guided PEEP titration on local lung ventilation, shunt, dead space, and…
- Trial name
- NCT06697717
- Testing
- Transpulmonary Pressure-Guided PEEP Titration in IAH and ARDS Patients, EIT-Guided PEEP Titration in IAH and ARDS Patients
- Where
- China
- Volunteers
- 15 people
- Sponsor
- XiaoJing Zou,MD
Diabetes Mellitus, Diabetic Kidney Disease
DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study
SGLT2 inhibitors such as ertugliflozin improve blood pressure and kidney outcomes in people living with diabetes through incompletely understood mechanisms, however, not all patients treated with SGLT2 inhibition have improved…
- Conditions
- Diabetes Mellitus, Diabetic Kidney Disease, Hypertension
- Trial name
- DESIGN (NCT05727579)
- Testing
- Salt-Diet and/or Ertugliflozin, Ertugliflozin 15 mg
- Where
- Netherlands
- Volunteers
- 41 people
- Sponsor
- Amsterdam UMC, location VUmc
Hypertension
Individually Tailored Web-Based Program to Improve Blood Pressure Control
High blood pressure affects 65 million adults in the United States, and more than one third of these individuals do not have adequate control of their blood pressure.
- Trial name
- NCT00377208
- Testing
- Web-Based Intervention
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Glaucoma
The Laser in Pseudoexfoliation (LIP) Study
A number of large clinical trials have found pseudoexfoliation (PXF) to be a major risk factor for glaucoma progression and risk of blindness.
- Trial name
- LIP (NCT01704989)
- Testing
- SLT Laser, Prostagladin
- Where
- Canada
- Sponsor
- Nova Scotia Health Authority
Diabetes Mellitus, Type 2, Obesity
Microclinic Social Network Behavioral Health Trial in Jordan
This 3-armed randomized controlled trial aims to evaluate the effectiveness of The Microclinic Behavioral Health Program in improving obesity and diabetes risk factors through a behavioral intervention program structured to…
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Hypertension, Hyperglycemia
- Trial name
- NCT01818674
- Testing
- Microclinic Behavioral Health Full Program (education curriculum in classroom setting, plus full social interaction program), Microclinic Behavioral Health Basic Program (education-only in classroom setting; no structured social interactions)
- Where
- 3 sites in Jordan
- Volunteers
- 914 people
- Sponsor
- Microclinic International
Hypertension
Improving BP Control in Diverse Populations Using BP MAP
BP-MAP is a cluster randomized controlled trial (RCT) designed to compare the effectiveness of BP lowering from a clinic-based quality improvement program with Full Support (dedicated practice facilitation) vs.
- Trial name
- BP MAP (NCT03818659)
- Testing
- Self-Guided M.A.P. BP Improvement Program, Full Support M.A.P. BP Improvement Program
- Where
- 24 sites in United States
- Volunteers
- 1,238,835 people
- Sponsor
- University of California, San Francisco
Hypertension
A Cluster-Randomized Trial of a Hypertension Risk Model-Based Precision Intervention in High-Risk Adults in Shunyi District
This community cluster-randomized controlled trial aims to evaluate the effectiveness of a hypertension risk model-based precision intervention among adults at high risk of developing hypertension in Shunyi District, Beijing…
- Trial name
- NCT07804420
- Testing
- Hypertension Risk Model-Based Precision Intervention, Standard Health Education
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Peking University
Pulmonary Arterial Hypertension
Hypotonic Treprostinil Subcutaneous Infusion for Control of Treprostinil Related Site Pain
The investigators will test whether hypotonic (diluted) remodulin solution causes less pain than the eutonic (undiluted) solution supplied by the manufacturer.
- Trial name
- NCT01615627
- Testing
- HypotonicTreprostinil Solution, Eutonic Treprostinil Solution
- Where
- Canada
- Sponsor
- Jewish General Hospital
Hypertension
Valsartan/Hydrochlorothiazide Combination in Hypertensive Patients Not Controlled With Valsartan Alone
This study will test the effectiveness and safety of a combination treatment in patients whose blood pressure is not controlled with a single medication.
- Trial name
- NCT00170989
- Testing
- valsartan plus hydrochlorothiazide
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 2,714 people
- Sponsor
- Novartis
Obesity
Spirulina Supplementation and Cardiovascular Risk in Obese Caucasians With Treated Hypertension
Potential protective cardiovascular effect of Spirulina maxima supplementation was studied in a double-blind placebo-controlled trial of obese subjects with treated hypertension, each randomized to receive spirulina or a placebo.
- Trial name
- NCT02575690
- Testing
- Spirulina
- Volunteers
- 50 people
- Sponsor
- Poznan University of Medical Sciences
Renovascular Hypertension, Renovascular Hypertension With Renal Failure
Effects of Percutaneous Transluminal Renal Angioplasty of Atherosclerotic Renal Artery Stenosis in High-Risk Patients.
The goal of this clinical trial is to document a beneficial effect of percutaneous transluminal renal angioplasty (PTRA) of atherosclerotic renal artery stenosis in high-risk patients selected according to the criteria used in…
- Conditions
- Renovascular Hypertension, Renovascular Hypertension With Renal Failure, Heart Failure, Renal Artery Stenosis Atherosclerotic
- Trial name
- DAN-PTRAII (NCT05834803)
- Testing
- Optimal medical therapy (OMT), Catheter-based angiography, Measurement of translesional pressure gradients
- Where
- 3 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Hypertensive Disorders of Pregnancy (HDP), Hypertension, Pregnancy Induced
Community Support and Mobile Apps to Help Black Women Control High Blood Pressure After Pregnancy
The goal of this randomized clinical trial is to evaluate the effectiveness of a collaborative care intervention, consisting of remote blood pressure monitoring and support from community health workers, in improving blood…
- Conditions
- Hypertensive Disorders of Pregnancy (HDP), Hypertension, Pregnancy Induced, Severe Maternal Morbidity, Postpartum Hypertension
- Trial name
- PRIME CARE (NCT07606027)
- Testing
- Collaborative care, Standard of Care (SOC)
- Volunteers
- 404 people
- Sponsor
- University of Nebraska
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