Clinical trials: Controlled Hypertension
Pregnancy
Education and Counseling Program on Pregnant Women With Risk of Preeclampsia
The aim of the study is to evaluate the effect of education and counseling program on healthy lifestyle behaviors, self-efficacy and maternal/neonatal consequences of pregnant women with risk of preeclampsia.
- Trial name
- NCT04036786
- Testing
- study group, standard care
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Portal Hypertension
The Effect of Probiotics (VSL) on Portal Hypertension
The investigators will address the hypothesis that portal hypertension is mediated in part by bacterial or endotoxin translocation and the production of inflammatory mediators (tumor necrosis factor-α (TNFα), etc.).
- Trial name
- NCT01032941
- Testing
- Probiotic
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Pulmonary Hypertension
Safety and Efficacy Study of Sitaxentan Sodium (Thelin™) in Patients With Pulmonary Arterial Hypertension
The purpose of this study is to evaluate the safety and efficacy of Thelin™ (sitaxsentan sodium) compared to placebo (sugar pill) in the treatment of patients with pulmonary arterial hypertension (PAH).
- Trial name
- NCT00080457
- Testing
- sitaxsentan sodium
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Encysive Pharmaceuticals
Hemorrhagic Strokes, Postoperative Hypertension
A Comparison of Nicardipine and Labetalol for Blood Pressure Control in Intensive Care Patients After Hemorrhagic Stroke Brain Surgery
Patients with hemorrhagic stroke who undergo brain surgery (craniotomy) often experience high blood pressure after surgery. Poor blood pressure control can increase the risk of bleeding, brain injury, and other serious…
- Conditions
- Hemorrhagic Strokes, Postoperative Hypertension, Hemodynamic Instability
- Trial name
- NIC-LAB ICU (NCT07364201)
- Testing
- Nicardipine, Labetalol
- Where
- Indonesia
- Volunteers
- 30 people
- Sponsor
- Universitas Sumatera Utara
Valid MeSH Conditions, Hypertension (HTN)
Mortality Outcome of Controlled Blood Pressure Participants
Despite advances in antihypertensive therapy, some patients with well-controlled blood pressure still experience fatal outcomes.
- Trial name
- HTN-Mort (NCT07067632)
- Testing
- Antihypertensive treatment
- Where
- Thailand
- Volunteers
- 246,587 people
- Sponsor
- DejthidaNathaphong
Pulmonary Hypertension, Iron Deficiency
The Impact of IV Iron on Exercise Capacity and Quality of Life in Pulmonary Hypertension
Pulmonary hypertension (PH) is a condition characterized by elevated blood pressure in the pulmonary arteries. This leads to symptoms such as shortness of breath and a significantly reduced exercise capacity, resulting in a very…
- Trial name
- IRON-PH (NCT07359599)
- Testing
- Ferric Carboxymaltose (FCM), Sodium Chloride (NaCl) 0.9 %
- Where
- 7 sites in Belgium
- Volunteers
- 306 people
- Sponsor
- Ziekenhuis Oost-Limburg
Hypertension
A Study To Evaluate The Dose-Related Efficacy and Safety of PS433540 in Subjects With Hypertension
The purpose of this study is to learn which doses of PS433540 should be given to patients with high blood pressure to lower their blood pressure.
- Trial name
- NCT00635232
- Testing
- irbesartan, PS433540
- Where
- 40 sites in United States
- Volunteers
- 261 people
- Sponsor
- Ligand Pharmaceuticals
Hypertension, Stress, Psychological
Effectiveness of Prazosin on the Urinary Sodium Excretion Response to Mental Stress
High blood pressure, or hypertension, is a serious problem in the African-American (AA) population which affects nearly 7 of every 10 AAs in our area.
- Conditions
- Hypertension, Stress, Psychological, Blood Pressure
- Trial name
- NCT02431936
- Testing
- Prazosin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Augusta University
CKD5 Stage Dialysis, Heart Failure
Sacubitril/Valsartan for CKD5 Stage Dialysis Patients
Hemodialysis or peritoneal dialysis CKD5 patients were randomly divided into Sacubitril/Valsartan and irbesartan treatment groups.
- Trial name
- NCT05243199
- Testing
- Sacubitril/Valsartan, Irbesartan
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Ruijin Hospital
Glaucoma, Visual Acuity
Buyang Huanwu Decoction and Normal Tension Glaucoma
The goal of this clinical trial is to test Buyang Huanwu Decoction in normal intra-ocular pressure glaucoma. The main question to answer is: the effect of Buyang Huanwu Decoction and its safety in patients with normal…
- Conditions
- Glaucoma, Visual Acuity, Visual Field, Chinese Medicine
- Trial name
- NCT06054763
- Testing
- Buyang Huanwu Decoction
- Volunteers
- 60 people
- Sponsor
- China Medical University Hospital
Hypertension
Efficacy/Safety of Cilnidipine Plus Valsartan Versus Valsartan in Patients With Hypertension
The purpose of this study is to evaluate of efficacy and safety of cilinidipine plus valsartan and valsartan alone in patients with essential hypertension inadequately controlled on valsartan monotherapy
- Trial name
- NCT02145104
- Testing
- valsartan 160mg, cilnidipine 10mg, cilinidipine 5mg
- Where
- South Korea
- Volunteers
- 286 people
- Sponsor
- IlDong Pharmaceutical Co Ltd
Pre-Eclampsia, Obesity
Evaluating the Effectiveness of a Food is Medicine Community Health Worker Program for Pregnant Women
The purpose of this study is to conduct a pilot randomized controlled trial of a food is medicine community health worker intervention called the Women's Health Delaware Food Farmacy compared to the usual standard of care among…
- Conditions
- Pre-Eclampsia, Obesity, Gestational Diabetes, Gestational Hypertension
- Trial name
- NCT06180811
- Testing
- Women's Health Delaware Food Farmacy, Usual Standard of Care
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Christiana Care Health Services
Hypertension, Pulmonary
A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension
The purpose of this study is to evaluate whether the addition of selexipag to standard of care treatment delays disease progression in children with Pulmonary Arterial Hypertension (PAH) in comparison to placebo.
- Trial name
- SALTO (NCT04175600)
- Testing
- Selexipag, Standard of Care (SOC): Endothelin receptor antagonist, SOC: Phosphodiesterase type 5 (PDE-5) inhibitor
- Where
- 116 sites in United States, Australia and 30 more
- Volunteers
- 138 people
- Sponsor
- Actelion
Hypertension
Treatment of Hypertension in Tibetan Adult Population
Several surveys had revealed that Tibetan adults had high prevalence of hypertension. However, there was no research studying the antihypertensive effect of the known drugs in Tibetan.
- Trial name
- NCT02217852
- Testing
- Nitrendipine, Hydrochlorothiazide, Captopril,Hydrochlorothiazide
- Where
- China
- Volunteers
- 800 people
- Sponsor
- West China Hospital
Cholecystitis; Gallstone, Mechanical Ventilation Pressure High
The Effect of Ventilation Modes on Cerebral Oxymetry In Operation
In laparoscopic cholecystectomy method, Insufflation of CO2 in abdominal cavity causes positioning of the diaphragm upwards, a decrease in lung's volume and its compliance, an increase in the airway resistance, mismatch between…
- Conditions
- Cholecystitis; Gallstone, Mechanical Ventilation Pressure High, Intraabdominal Hypertension
- Trial name
- NCT04723043
- Testing
- mechanical ventilation modes
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Idiopathic Intracranial Hypertension (IIH)
Eptinezumab for Chronic Headache in Idiopathic Intracranial Hypertension
The goal of this clinical trial is to learn if eptinezumab can reduce headache frequency and headache-related disability in adults with idiopathic intracranial hypertension (IIH) and chronic headache.
- Trial name
- PRIMA (NCT07645833)
- Testing
- Eptinezumab
- Volunteers
- 96 people
- Sponsor
- Rigmor Højland Jensen
Glaucoma
Efficacy of SLT in Patients With Insufficient IOP Control Under Maximum Tolerated Drug Therapy (Eye Drops)
Examination and follow-up of efficacy and safety of SLT in patients with unsufficient IOP control despite maximum tolerated topical therapy.
- Trial name
- NCT00801658
- Testing
- selective Laser Trabeculoplasty (SLT)
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Resistant Hypertension
A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and Find Out More About Its Safety
The goal of this clinical trial is to show the blood pressure lowering effect of aprocitentan, a new drug, when added to other anti-hypertensive drugs of patients with difficult to control (resistant) high blood pressure…
- Trial name
- PRECISION (NCT03541174)
- Testing
- Aprocitentan 12.5 mg, Aprocitentan 25 mg
- Where
- 159 sites in United States, Australia and 18 more
- Volunteers
- 730 people
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Primary Open Angle Glaucoma, Ocular Hypertension
Ph2 Placebo-Controlled Study for Safety & Ocular Efficacy of SBI-100 Ophthalmic Emulsion in Pts w/ Elevated Eye Pressure
The goal of this clinical trial is to test in patients with glaucoma and elevated pressure in the eye. The main questions it aims to answer are: • ability to lower pressure in the eye • safety in the eye and the body of patients…
- Trial name
- NCT06144918
- Testing
- SBI-100 Ophthalmic Emulsion, 0.5%, SBI-100 Ophthalmic Emulsion, 1.0%
- Where
- 3 sites in United States
- Volunteers
- 56 people
- Sponsor
- Skye Bioscience, Inc.
Glaucoma
Travoprost/Timolol vs Latanoprost/Timolol Fixed Combination Therapy
The primary objective of this crossover trial is to compare the 3-month, mean 24-hour intraocular pressure (IOP) control and safety obtained with two popular fixed combinations in glaucoma patients insufficiently controlled with…
- Trial name
- NCT01779284
- Testing
- Travoprost/timolol therapy, Latanoprost/Timolol therapy
- Where
- Greece
- Volunteers
- 42 people
- Sponsor
- Aristotle University Of Thessaloniki
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