Clinical trials: Corneal re-Epithelialization
Corneal Dystrophy, Epithelial Basement Membrane, Epithelial Recurrent Erosion Dystrophy
Cacicol20® in Corneal Wound Healing and Nerve Regeneration After Phototherapeutic Keratectomy
The objective of this clinical study is to test the efficacy of CACICOL20® (RGTA OTR 4120) in improving wound healing and nerve regeneration in the anterior cornea, in a patient population undergoing therapeutic laser treatment…
- Conditions
- Corneal Dystrophy, Epithelial Basement Membrane, Epithelial Recurrent Erosion Dystrophy, Corneal Erosions
- Trial name
- CACICOL-PTK (NCT02373397)
- Testing
- Cacicol20
- Where
- 2 sites in Sweden
- Volunteers
- 40 people
- Sponsor
- Neil Lagali
Corneal re-Epithelialization
A Study to Assess the Safety, Tolerability and Effect of Nexagon™ Applied to the Eye After PRK Laser Eye Surgery for Nearsightedness
Phase 1 randomized, prospective, double-masked, vehicle-controlled, dose-escalation study to evaluate the safety, tolerability and clinical effect of Nexagon™ in subjects following bilateral PRK for the correction of mild to…
- Trial name
- NCT00654550
- Testing
- Nexagon™ or Nexagon™ vehicle
- Where
- New Zealand
- Volunteers
- 24 people
- Sponsor
- OcuNexus Therapeutics, Inc.
Dry Eye Syndromes
A Study to Assess the Safety and Effectiveness of SJP-0035 for the Treatment of Patients With Dry Eye Disease
A double-masked, randomized, multi-center, placebo-controlled, parallel-group study in adult patients with Dry Eye Disease (DED). Patients will be randomly assigned to receive either SJP-0035 0.001% or placebo
- Trial name
- NCT03527212
- Testing
- SJP-0035 0.001%
- Where
- 23 sites in United States
- Volunteers
- 329 people
- Sponsor
- Senju Pharmaceutical Co., Ltd.
Corneal Wound Healing
Sutureless Cryopreserved Amniotic Membrane Graft (ProKera) and Wound Healing After Photorefractive Keratectomy
The purpose of this study is to evaluate the effect of ProKera on corneal wound healing after photorefractive keratectomy (PRK) in terms of re-epithelialization, pain, adverse effects, visual recovery, refractive accuracy, and…
- Trial name
- NCT00915759
- Testing
- ProKera, Bandage contact lens
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Photorefractive Keratectomy, Corneal De-epithelialization
Study to Evaluate the Efficacy of Lagricel® Ofteno PF Compared to Thealoz® Duo After Photorefractive Keratectomy
Phase IV comparative, controlled, parallel group, open, randomized multicenter study to evaluate the efficacy of Lagricel® Ofteno PF Compared to Thealoz® Duo.
- Trial name
- PRO-037 (NCT04704518)
- Testing
- Sodium Hyaluronate Ophthalmic 0.4%, Trehalose 3% / Sodium Hyaluronate Ophthalmic 0.15%
- Where
- Mexico
- Volunteers
- 96 people
- Sponsor
- Laboratorios Sophia S.A de C.V.
Ophthalmology, Photorefractive Keratectomy ("PRK")
Ocular Bandage Gel (OBG) Pivotal Trial in Patients Undergoing Photorefractive Keratectomy ("PRK")
Prospective, randomized, masked (reading center), controlled pivotal study of Ocular Bandage Gel (OBG) vs. a bandage contact lens (BCL) in subjects who have undergone bilateral photorefractive keratectomy (PRK).
- Conditions
- Ophthalmology, Photorefractive Keratectomy ("PRK"), Laser Assisted Surgery, Refractive Surgery
- Trial name
- NCT03938883
- Testing
- Ocular Bandage Gel (OBG), Bandage Contact Lens (BCL)
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Eyegate Pharmaceuticals, Inc.
Corneal Epithelial Defects After Ocular Surgeries
Topical Autologous Insulin Application for the Treatment of Corneal Epithelium Defect After Ocular Surgeries
Topical insulin application has been proved recently to increase corneal reepithelization rate over diabetic animals. However, its effectiveness on corneal epithelial wound healing in patients who received pars planar vitrectomy…
- Trial name
- NCT01031888
- Testing
- Topical insulin eye drops, Conventional postoperative eye drops
- Where
- Taiwan
- Volunteers
- 18 people
- Sponsor
- National Taiwan University Hospital
Corneal Epithelial Wound
Safety and Effectiveness of OBG vs.a Bandage Contact Lens for Large Corneal Epithelial Defects in Patients Post-PRK.
This is a prospective, randomized (Reading Center), masked, controlled study in up to 45 subjects who have undergone bilateral PRK with epithelial removal using alcohol in a 9.0 mm well or trephine at the time of surgery to…
- Trial name
- NCT03163641
- Testing
- Acuvue Oasys, Ocular Bandage Gel
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Eyegate Pharmaceuticals, Inc.
Corneal Epithelial Wound Healing
Evaluation of Dexpanthenol and Hyaluronic Acid Eye Drops on Corneal Epithelialization After Trans Epithelial PRK
The aim of this prospective, contralateral, randomized, double-blind, placebo-controlled study is the evaluation of the performance of a fixed combination of dexpanthenol and hyaluronic acid preservative-free eye artificial tears…
- Trial name
- NCT06822608
- Testing
- dexpanthenol and hyaluronic acid preservative-free eye artificial tears eye drops
- Where
- Greece
- Volunteers
- 68 people
- Sponsor
- National and Kapodistrian University of Athens
Corneal Erosion
Facilitation of Corneal Re-epithelialization After Photorefractive Keratectomy
Photorefractive keratectomy (PRK) or surface ablation is one of the most commonly used surgical procedures to correct refractive errors, which was proved to be safe and effective.
- Trial name
- NCT03739255
- Testing
- Cacicol20
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- SynsLaser Kirurgi AS