Clinical trials: Coronary; Ischemic
Coronary Artery Disease
Continued Ventilation During Cardiopulmonary Bypass
Cardiopulmonary bypass (CPB) is well known to induce a strong anti-inflammatory response. The investigators examined whether continued mechanical ventilation during CPB alters systemic immune activation.
- Trial name
- NCT01627756
- Testing
- Lung Ventilation, Non-ventilated Group
- Where
- Hungary
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Coronary Arteriosclerosis, Atrial Fibrillation
A(f)MAZE-CABG Study
Concomitant AF ablation with HIFU in patients with persistent or long standing persistent AF undergoing CABG will be superior in restoring SR, compared with patients with persistent or long standing persistent AF undergoing CABG…
- Conditions
- Coronary Arteriosclerosis, Atrial Fibrillation, Coronary Artery Bypass Graft Surgery
- Trial name
- AFMAZE-CABG (NCT00735722)
- Testing
- HIFU AF Ablation
- Where
- 10 sites in Canada, Finland and 4 more
- Volunteers
- 188 people
- Sponsor
- Abbott Medical Devices
Coronary Heart Disease
A Cohort Study of PCI Strategies for Severely Calcified Lesions of Complex Coronary Arteries in the Elderly
The aim of this observational study is to compare the prognostic outcomes of various PCI strategies in elderly patients with complex coronary calcified lesions.
- Trial name
- PSSCCE (NCT06168422)
- Testing
- DES, DCB
- Where
- China
- Volunteers
- 2,100 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Myocardial Infarction
Implementation and Validation of Telemedicine Software for the Automation of MRI Examinations of Acute Myocardial Infarctions
Validation of a telemedicine software application for an automated treatment of cardio-vascular MRI completely identical for both CHUs.
- Trial name
- TELECARD (NCT03601481)
- Volunteers
- 167 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Coronary Disease, Cardiovascular Diseases
Cardiac and Renal Disease Study (CARDS)
To examine the epidemiology of renal disease and its relationship to cardiovascular disease.
- Conditions
- Coronary Disease, Cardiovascular Diseases, Cerebrovascular Accident, Heart Failure
- Trial name
- NCT00049907
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Patent Foramen Ovale, Cryptogenic Stroke
Encore PFO Closure Device - The PerFOrm Trial
The objective of this study is to establish reasonable assurance of safety, effectiveness, and noninferiority of the Encore PFO closure device when compared to any investigator chosen FDA-approved PFO closure device.
- Trial name
- NCT05537753
- Testing
- Encore PFO closure device, FDA-approved PFO closure device
- Where
- 8 sites in United States
- Volunteers
- 500 people
- Sponsor
- Encore Medical Inc.
Coronary Artery Disease
Assessment of Translesional Markers and Metabolomics
Blockages in the blood vessels of the heart are the main cause of chest pain, heart attacks, and sudden death. A cardiac catheterization, or injecting x-ray dye into the blood vessels of the heart and taking pictures, is…
- Trial name
- NCT00321139
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Emory University
Cardiovascular Diseases, Cerebrovascular Accident
Low Cholesterol and Mortality in Blacks and Women
To determine and compare the long term (thirty year) relationship of total cholesterol and mortality in Blacks and whites in a predominantly urban Charleston, South Carolina cohort and a predominantly rural Evans County, Georgia…
- Conditions
- Cardiovascular Diseases, Cerebrovascular Accident, Coronary Disease, Heart Diseases
- Trial name
- NCT00005430
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Acute Myocardial Infarction, Unstable Angina
Exploring the Mechanism of Plaque Rupture in Acute Coronary Syndrome Using Coronary CT Angiography and Computational Fluid Dynamics II (EMERALD II) Study
The EMERALD II study is a multinational, multicenter, and retrospective study. ACS patients who underwent CCTA from 1 months to 3 years prior to the event will be retrospectively identified.
- Trial name
- EMERALD II (NCT03591328)
- Testing
- Coronary CT angiography
- Where
- South Korea
- Volunteers
- 429 people
- Sponsor
- Seoul National University Hospital
Coronary Artery Disease
Coronary Artery and Coronary Artery Bypass Graft Imaging Using a Specialized Catheter and Computed Tomography
The present study relates to a new approach to coronary artery and coronary artery by-pass graft imaging, and more particularly to computed tomographic angiography following an aortic root injection of a low amount of contrast…
- Trial name
- NCT00474565
- Testing
- Placement of an aortic root pigtail catheter.
- Where
- United States
- Sponsor
- Corewell Health East
Chronic Stable Angina
Phase IIb Study of STA-2 in Patients With Chronic Stable Angina
The objective of this study is to evaluate the dose-response of three different dose levels of STA-2 (900 mg daily, 1800 mg daily and 2700 mg daily for 42 days) versus placebo in patients with chronic stable angina.
- Trial name
- NCT01239511
- Testing
- green tea polyphenols (STA-2)
- Where
- 5 sites in Taiwan
- Volunteers
- 186 people
- Sponsor
- Sinphar Pharmaceutical Co., Ltd
Myocardial Infarction, Inflammation
Effects of Oxygen Treatment on Mechanisms Involved in Ischemia-reperfusion Injury: A Pilot Study in Healthy Volunteers
Oxygen treatment is widely used in acutely ill patients. In particular, oxygen treatment is routinely used in acute coronary syndrome (ACS) patients with suspected acute myocardial infarction and variably recommended in…
- Conditions
- Myocardial Infarction, Inflammation, Acute Coronary Syndrome (ACS), Reperfusion Injury
- Trial name
- NCT02286544
- Testing
- Salmonella typhi vaccine (Typhim Vi®), Oxygen (Oxymask®), Atorvastatin
- Where
- Sweden
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Coronary Artery Disease, High-risk Percutaneous Coronary Intervention
Early Feasibility Study of the Supira System in Patients Undergoing HRPCI
The objective of this study is to assess the feasibility and safety of the Supira System in providing temporary cardiovascular hemodynamic support in patients undergoing HRPCI.
- Conditions
- Coronary Artery Disease, High-risk Percutaneous Coronary Intervention, Interventional Cardiology
- Trial name
- NCT06087575
- Testing
- Supira System
- Where
- 4 sites in United States
- Volunteers
- 15 people
- Sponsor
- Supira Medical
Coronary Artery Disease, Coronary Disease
Optimal dRug Eluting steNts Implantation Guided By Intravascular Ultrasound and Optical coheRence tomoGraphy ORENBURG
The objective of this research is to assess the clinical results of implantation of different drug eluting stents under "aggressive" intravascular ultrasound (IVUS) guided all the way up to 24 months after operation and to…
- Conditions
- Coronary Artery Disease, Coronary Disease, Heart Diseases
- Trial name
- ORENBURG (NCT01917201)
- Testing
- IVUS-guided group, Non-IVUS group
- Where
- Russia
- Volunteers
- 1,000 people
- Sponsor
- The Orenburg Regional Clinical Hospital
Atrial Fibrillation, Stroke
Feasibility and Safety Study of LAmbre Left Atrial Appendage Occluder
This study mainly evaluated the feasibility and safety of LAmbre Left Atrial Appendage Occluder which is to prevent ischemic stroke caused by atrial fibrillation(AF).
- Trial name
- NCT01920412
- Testing
- LAmbre Left Atrial Appendage(LAA) Occluder
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Lifetech Scientific (Shenzhen) Co., Ltd.
Coronary Artery Disease
Notify 2: An Evaluation of the Impact of Notification of Incidental Coronary Artery Calcium on Statin Rates
The primary objective is to estimate the impact of notification of primary care provider and patient of at least moderate incidental coronary artery calcification (CAC) on a prior non-gated chest CT on statin prescription rates…
- Trial name
- NCT05394181
- Testing
- Notification
- Where
- United States
- Sponsor
- Stanford University
Coronary Disease
International Post PCI FFR Registry
The prognostic factors after a percutaneous coronary intervention (PCI) have not been comprehensively investigated. The investigators sought to develop a risk model to predict future clinical events after PCI using contemporary…
- Trial name
- NCT04012281
- Testing
- Percutaneous coronary intervention
- Volunteers
- 2,228 people
- Sponsor
- Seoul National University Hospital
Coronary Artery Disease
Carotid Atherosclerosis: MEtformin for Insulin ResistAnce Study
Hypothesis: Treatment with metformin in overweight non-diabetic individuals with coronary heart disease and on standard cardiovascular risk reducing agents including statins will have a beneficial impact on carotid artery…
- Trial name
- CAMERA (NCT00723307)
- Testing
- Metformin
- Where
- United Kingdom
- Volunteers
- 173 people
- Sponsor
- Professor Naveed Sattar
Myocardial Ischemia, Physical Exercise
Randomized Clinical Trial by Conglomerates on the Efficacy of Maintenance of Physical Exercise in Myocardial Ischemia
Main objective: To assess the efficacy of a phase III cardiac rehabilitation program (CRP), based on counseling in the maintenance of physical exercise (time of physical exercise per week) for patients with myocardial ischemia…
- Trial name
- CarPE3 (NCT04251611)
- Testing
- Maintenance of physical exercise
- Where
- Spain
- Volunteers
- 101 people
- Sponsor
- Núria Santaularia Capdevila
Cardiovascular Diseases, Coronary Artery Disease
Supporting Methods in Cardiovascular Diseases Rehabilitation
The study evaluates how various therapeutic approaches perform in addressing depression, anxiety symptoms, and stress levels among patients in the second stage of cardiac rehabilitation.
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Mood Disorders, Depressive Symptoms
- Trial name
- NCT06241534
- Testing
- Cardiac rehabilitation, Relaxation-therapeutic recordings, Virtual reality therapy
- Where
- Poland
- Volunteers
- 45 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.