Clinical trials: Coronary Angioplasty
Myocardial Reperfusion Injury
POSTconditioning During Coronary Angioplasty in Acute Myocardial Infarction Study
The POST-conditioning during coronary angioplasty in Acute Myocardial Infarction (POST-AMI) trial will evaluate the usefulness of postconditioning in limiting infarct size and microvascular damage during the early and late phases…
- Trial name
- POST-AMI (NCT01004289)
- Testing
- Postconditioning, Primary angioplasty and stenting without additional intervention
- Where
- Italy
- Volunteers
- 78 people
- Sponsor
- University of Padova
Acute Myocardial Infarction With ST Elevation
Dextran Use for Primary Angioplasty Protection in Acute Myocardial Infarction
Reperfusion therapy in acute myocardial infarction saves viable myocardium, but paradoxically reestablishment of coronary artery flow also induces damage and cell death, decreasing the full benefit of reperfusion in terms of…
- Trial name
- DUPAP (NCT03148834)
- Testing
- Controlled Reperfusion
- Volunteers
- 100 people
- Sponsor
- Centro Cardiovascular Salta
Critical Limb Ischemia, Peripheral Artery Disease
Tack Optimized Balloon Angioplasty Below the Knee (TOBA - BTK) Study
Multi-center study to optimize below the knee (BTK) balloon angioplasty results by creating tissue apposition in peripheral arteries with Reference Vessel Diameter's (RVD) ranging from 1.5mm to 4.5mm.
- Trial name
- TOBABTK (NCT02235675)
- Testing
- Tack-It Endovascular System
- Where
- Austria
- Volunteers
- 35 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Myocardial Infarction, Unstable Angina
Evaluation of an Introductory Videotape Intervention to Improve Cardiac Rehabilitation Participation
The purpose of this study is to determine whether a pre-discharge videotape introducing the concept and benefit of a Cardiac Rehabiliation \& Secondary Prevention (CRSP) program will increase intent to participate in a CRSP…
- Conditions
- Myocardial Infarction, Unstable Angina, Coronary Angioplasty, Coronary Artery Bypass Surgery
- Trial name
- NCT00372671
- Testing
- Survey, Survey and videotape
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Femoral Artery Stenosis, Angioplasty
an Observational Study Evaluting the Effectiveness and Safety of DKutting LL Noval Scoring Balloon Angioplasty for Vessel Preparation Facilitated by IVUS on the Lower Limb Ischemia Patients With Calcified Lesions
This is a prospective, single-center, single-arm, observational study. It plans to enroll 58 patients with moderate to severely calcified lesions in the femoropopliteal or infrapopliteal arteries.
- Conditions
- Femoral Artery Stenosis, Angioplasty, Cutting Balloon Angioplasty, Calcifications, Vascular
- Trial name
- DkuLL CALVEP (NCT07397390)
- Testing
- DKutting LL scoring balloon angioplasty
- Where
- China
- Volunteers
- 58 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Coronary Artery Lesions With Implantation of Coronary Device
REPARA Study: REgistry of PAtients With bioResorbable Device in Daily Clinical prActice
A multicentre, observational, prospective device registry, with no control group, designed to evaluate the efficacy and safety of the bioresorbable coronary device, used according to the indications of use, in daily clinical…
- Trial name
- REPARA (NCT02256449)
- Where
- Spain
- Volunteers
- 2,440 people
- Sponsor
- Sección Hemodinamica y Cardiologia Intervencionista
Coronary Artery Bypass, Atherosclerosis
Study of the Xience V Everolimus-eluting Stent in Saphenous Vein Graft Lesions
The specific aim of the SOS-Xience V study is to examine the 12-month incidence of binary angiographic in-stent restenosis after implantation of the Xience V stent in aortocoronary saphenous vein bypass graft lesions.
- Trial name
- SOS-Xience V (NCT00911976)
- Testing
- Xience V coronary stent
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- North Texas Veterans Healthcare System
Peripheral Vascular Disease
Popliteal Artery of Treatment With Balloon Angioplasty vs. SUPERA VERITAS Peripheral Stent System
Unblinded, randomized, balanced trial comparing 12 month target lesion patency rates of the IDEV SUPERA VERITAS peripheral stent system to PTA in the treatment of obstructive atherosclerotic popliteal artery disease.
- Trial name
- PARADIGM (NCT01667393)
- Testing
- IDEV SUPERA Stent, Percutaneous Transluminal Angioplasty
- Sponsor
- Abbott Medical Devices
Coronary Artery Bypass, Arteriosclerosis
The SOS (Stenting Of Saphenous Vein Grafts) Trial
The main purpose of this study is to determine whether implantation of a paclitaxel-eluting stent (Taxus™) in saphenous vein graft lesions will reduce the incidence of in-stent restenosis after 12 months when compared to a…
- Trial name
- NCT00247208
- Testing
- Taxus polymer-based paclitaxel-eluting stent, Express 2 bare metal stent
- Where
- 5 sites in United States, Greece
- Volunteers
- 80 people
- Sponsor
- North Texas Veterans Healthcare System
Acute Myocardial Infarction
Optical Coherence Tomography Assessment of Gender diVersity In Primary Angioplasty: The OCTAVIA Trial
Recent studies suggest important gender differences in the pathophysiology and prognosis of ST-segment elevation myocardial infarction (STEMI).
- Trial name
- OCTAVIA (NCT02577965)
- Testing
- Percutaneous Coronary Intervention, XIENCE PRIME Everolimus Eluting Coronary Stent System
- Volunteers
- 140 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Vascular Graft Anastomotic Stenosis
Drug-coated Balloon Versus Conventional Balloon Angioplasty in Hemodialysis Graft
To evaluate the role of DCB angioplasty for venous anastomotic stenosis of hemodialysis graft, investigators would like to perform randomized study comparing the results of drug- coated balloon angioplasty with conventional…
- Trial name
- NCT02706444
- Testing
- Conventional Balloon angioplasty, Drug-coated Balloon angioplasty
- Volunteers
- 190 people
- Sponsor
- Konkuk University Medical Center
Chronic Limb Threatening Ischemia
Laser Atherectomy and Sirolimus-eluting Balloon Angioplasty for CLTI
Peripheral arterial disease (PAD) is a widespread pathology affecting over 200 million adults globally and is primarily caused by atherosclerosis.
- Trial name
- LASER-S (NCT07858539)
- Testing
- Laser atherectomy followed by Sirolimus-eluting balloon angioplasty of femoropopliteal or infrapopliteal or both arterial stenosis or occlusions
- Where
- Greece
- Volunteers
- 55 people
- Sponsor
- Attikon Hospital
Cardiovascular Diseases
Non-invasive Peri- and Postoperative Monitoring of Femoral Artery Balloon Angioplasty
This study evaluates a novel noninvasive method to dynamically monitor the effect of percutaneous transluminal angioplasty on arterial pulse wave
- Trial name
- NCT02725307
- Testing
- Noninvasive pulse wave analysis sensor, ECG-sensor
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Tampere University Hospital
Peripheral Artery Disease
Sirolimus- vs. Paclitaxel-Drug Coated Ballons in Patients With Peripheral Artery Disease
This study is a prospective, interventional, multi-center 1:1 randomized non-inferiority trial. The trial evaluates the safety and efficacy of the Magic Touch PTA sirolimus drug-coated balloon in comparison to the treatment with…
- Trial name
- SIRONA (NCT04475783)
- Testing
- Percutaneous Transluminal Angioplasty (PTA)
- Where
- 22 sites in Austria, Germany
- Volunteers
- 478 people
- Sponsor
- Jena University Hospital
Drug Coated Balloon
Drug Coated Ballon in Critical Limb Ischemia
Evaluate the safety and efficacy of drug coated balloon (DCB) for the treatment of femoropopliteal lesions in patients with critical limb ischemia (CLI)
- Trial name
- DCB (NCT04737291)
- Testing
- drug coated balloon
- Volunteers
- 36 people
- Sponsor
- Assiut University
Cardiovascular Disease, Myocardial Infarction
A Prospective, Randomized Trial of BVS Veruss EES in Patients Undergoing Coronary Stenting for Myocardial Infarction
The aim of the current study is to test the clinical performance of the everolimus-eluting BVS compared with that of the durable polymer everolimus-eluting stent (EES) in patients undergoing PCI in the setting of acute MI.
- Conditions
- Cardiovascular Disease, Myocardial Infarction, Thrombus, Primary Angioplasty
- Trial name
- ISAR-Absorb MI (NCT01942070)
- Testing
- Bioresorbable vascular scaffold, Durable polymer everolimus-eluting metallic stent
- Where
- 2 sites in Germany
- Volunteers
- 262 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Angioplasty, Balloon, Coronary
COmparison of Xience PrimE Versus REsolute Integrity in Diabetes or Small Vessel Disease
The newer generation ZES (Medtronic, Minneapolis, MN, Resolute Integrity) and EES (Abbott Vascular, Abbott Park, Illinois, Xience Prime) were introduced to South Korea.
- Trial name
- COPERES (NCT01752127)
- Testing
- percutaneous coronary intervention using drug eluting stent
- Where
- South Korea
- Volunteers
- 600 people
- Sponsor
- Chonbuk National University Hospital
Femoropopliteal Lesion
DRug-Eluting BallOOn Versus Primary Polymer-coated Paclitaxel Eluting STenting for Femoro-popliteal Lesions
Main objective of the study: To demonstrate that a primary DCB strategy is non-inferior in terms of primary patency to a primary SEDES strategy for above-the-knee femoro-popliteal lesions at 12 months.
- Trial name
- REBOOST (NCT06835660)
- Testing
- procedure of DCB implantation, procedure of SEDES implantation
- Where
- France
- Volunteers
- 402 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ischemia, Stenosis
Paclitaxel-Eluting Balloon Angioplasty and Coroflex™-Stents in the Treatment of Bifurcated Coronary Lesions
The aim of the study is to investigate the feasibility of Paclitaxel-eluting PTCA-balloon dilation (SeQuent Please) followed by bare metal stent (Coroflex ) deployment in the main branch (reference diameter: ≥ 2.5 mm and ≤ 3.8…
- Trial name
- PEPCAD V (NCT00540813)
- Testing
- drug eluting balloon
- Where
- 2 sites in Germany
- Volunteers
- 28 people
- Sponsor
- Heart Centre Rotenburg
Coronary Angiogram, Early Discharge Trans Radial Angiography
Potassium Ferrate Hemostatic Sealant-Assisted Early Radial Hemostasis After Transradial Coronary Angiography and PCI
This study aims to evaluate patients undergoing coronary angiography by comparing the use of Potassium Ferrate Hemostatic Sealant (PFHS) in addition to the standard of care (SOC) pneumatic radial compression device versus SOC…
- Trial name
- MAHI-SEAL-60 (NCT07768839)
- Testing
- Experimental: PFHS + pneumatic radial compression device, Pneumatic radial compression device alone.
- Volunteers
- 300 people
- Sponsor
- University of Alberta