Clinical trials: Coronary Angioplasty
Arterial Occlusive Diseases, Cardiovascular Diseases
Evaluation of Effectiveness and Safety of Bioresorbable Vascular Scaffold in Routine Clinical Practice
The purpose of this study is to evaluate the relative effectiveness and safety of Bioresorbable Vascular Scaffold compared to other (drug eluting stents) DES.
- Conditions
- Arterial Occlusive Diseases, Cardiovascular Diseases, Coronary Artery Disease, Coronary Disease
- Trial name
- IRIS BVS (NCT02622100)
- Testing
- Bioresorbable Vascular Scaffold
- Where
- 14 sites in South Korea
- Volunteers
- 629 people
- Sponsor
- Duk-Woo Park, MD
Renal Artery Obstruction, Hypertension, Renovascular
Endovascular Therapy for Renal Artery Stenosis in China
A multicenter prospective registry planned to recruit more than 5 000 patients with renal artery stenosis was carried out in China.
- Trial name
- ETRAS-China (NCT03080519)
- Testing
- Endovascular Therapy
- Where
- 16 sites in China
- Volunteers
- 5,000 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Coronary Artery Disease, Ischaemic Heart Disease
Coronary Artery Endothelial Dysfunction With Drug Coated Balloons
Use of intracoronary acetylcholine to investigate endothelial function in coronary arteries treated with either drug coated balloon angioplasty of drug eluting stents.
- Conditions
- Coronary Artery Disease, Ischaemic Heart Disease, Endothelial Dysfunction
- Trial name
- SPARTAN-VM (NCT04901767)
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Coronary Artery Disease
Rotational Atherectomy for Calcified lEsion By Smart Angioplasty Research Team (SMART-RACE)
Current guidelines recommend the use of rotational atherectomy (RA) for preparation of heavily calcified or severely fibrotic lesions that cannot be crossed by a balloon or adequately dilated before planned stenting (bailout…
- Trial name
- NCT02716363
- Testing
- Rotational Atherectomy by Rotablator
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Samsung Medical Center
Peripheral Arterial Disease
TurboPower + DCB Treatment of Femoropopliteal De Novo/ Restenotic and In-Stent Restenosis Lesions
A retrospective study to evaluate Turbo Power laser atherectomy + drug coated balloon (DCB) angioplasty for the treatment of femoropopliteal de novo/restenotic lesions and in-stent restenosis (ISR).
- Trial name
- NCT03306199
- Testing
- Laser Atherectomy
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Spectranetics Corporation
Angina, Chronic Coronary Occlusion
XIENCE V/PROMUS Everolimus-Eluting Stent System Post-marketing Surveillance Protocol for Japan
The objectives of this post-marketing surveillance, conducted in Japan, is to know the frequency, type and degree of device malfunction, to assure the safety of the medical device, and to collect information on evaluation of the…
- Conditions
- Angina, Chronic Coronary Occlusion, Stent Thrombosis, Vascular Disease
- Trial name
- NCT01086228
- Testing
- XIENCE V / PROMUS stent
- Where
- 47 sites in Japan
- Volunteers
- 2,010 people
- Sponsor
- Abbott Medical Devices
Myocardial Infarction, Angioplasty, Balloon, Coronary
Comparison of Prasugrel and Ticagrelor in the Treatment of Acute Myocardial Infarction
This study evaluates the efficacy of Prasugrel and Ticagrelor in the treatment of acute myocardial infarction.
- Conditions
- Myocardial Infarction, Angioplasty, Balloon, Coronary, Platelet Aggregation Inhibitors
- Trial name
- PRAGUE-18 (NCT02808767)
- Testing
- Prasugrel, Ticagrelor
- Where
- Czechia
- Volunteers
- 1,226 people
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Coronary Artery Disease
Computational μFR-Guided Versus Angiographic Guidance in Drug-Coated Balloon Angioplasty
The MAGIC trial is an investigator-initiated, multicenter, randomized (1:1) interventional study designed to evaluate whether drug-coated balloon (DCB) angioplasty guided by computational μFR assessment is superior to…
- Trial name
- MAGIC (NCT07917234)
- Testing
- μFR-Based Group (Intervention)
- Where
- 4 sites in Italy
- Volunteers
- 250 people
- Sponsor
- Centro Cardiologico Monzino
Angina Pectoris, Angina, Unstable
Intravascular Near Infrared Spectroscopy (NIRS) Bifurcation - Lipid Core Plaque Shift Study
This pilot study is going to examine the hypothesis that in coronary arteries, soft lesions that contain lipid cores, but are not calcified or fibrotic and are located in proximity to side branches, are associated with side…
- Conditions
- Angina Pectoris, Angina, Unstable, Atherosclerosis, Coronary Artery Disease
- Trial name
- NCT00905671
- Testing
- LipiScan Coronary Imaging Catheter
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Infraredx
Myocardial Infarction
Coronary Anatomy Study and Times Since the Onset of Acute Myocardial Infarction Symptoms in Women Until the Opening of the Artery (TAPAC Study)
TAPAC study is an an investigator-driven, observational, prospective,cohort aimed at evaluating differences between men and women in patients undergoing primary angioplasty : hospital medical care, successful markers myocardial…
- Trial name
- TAPAC (NCT03152240)
- Testing
- Non intervention
- Where
- Spain
- Volunteers
- 800 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Myocardial Infarction, Occlusive Thrombus
Thrombus Aspiration for OcLuded Coronary Artery Enhanced With Distal Injection Of Abciximab
Aims: (to prove that) The distal injection of IIb IIIa platelet receptor blocker to the thrombus occlusion is better than normal injection during primary percutaneous intervention (PCI) for the treatment of acute myocardial…
- Trial name
- TOLEDO1 (NCT01383785)
- Testing
- Intracoronary direct injection, Intracoronary and distal injection by aspiration device, Intracoronary distal injection by aspiration catheter device
- Where
- Spain
- Volunteers
- 186 people
- Sponsor
- Hospital Virgen de la Salud
Myocardial Infarction
Safety of TG100-115 for Heart Attack Treated With Angioplasty
TG100-115 is able to reduce the size of heart attacks in pre-clinical models. The hypothesis of this study is that TG100-115 can be given safely to patients who suffer a heart attack and undergo angioplasty to restore blood flow.
- Trial name
- NCT00103350
- Testing
- TG100-115
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- TargeGen
High Bleeding Risk, Coronary Artery Disease
Zotarolimus vs Sirolimus Eluting Stent in High Bleeding Risk
Randomized, single-blind, single-center, non-inferiority clinical trial to compare target lesion failure (TLF) at 12 months in high bleeding risk patients who underwent elective coronary percutaneous intervention with a…
- Conditions
- High Bleeding Risk, Coronary Artery Disease, Percutaneous Coronary Intervention
- Trial name
- ZEVS-HBR (NCT05240781)
- Testing
- Zotarolimus eluting stent, Sirolimus eluting stent
- Where
- Mexico
- Volunteers
- 280 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Coronary Artery Disease
VIBE-assisted DEB Registry
VIBER aims at assessing angiographic outcome of drug-eluting balloon angioplasty assisted by the Vascular Imaging Balloon Catheter (VIBE, Volcano, San Diego, CA) device, which integrates a predilation catheter with electronic…
- Trial name
- VIBER (NCT01411462)
- Testing
- VIBE + drug-eluting balloon
- Where
- Italy
- Sponsor
- Ospedale Santa Maria Goretti
Ischemic Heart Disease, Coronary Artery Stenosis
A Clinical Evaluation of the MINI TREK RX 1.20 mm Coronary Dilatation Catheter in Stenotic Lesions
This is a prospective, single-arm, open-label, multi-center, observational study to assess the acute safety and efficacy of MINI TREK RX 1.20 mm for enlarging coronary luminal diameter during percutaneous coronary intervention…
- Conditions
- Ischemic Heart Disease, Coronary Artery Stenosis, Chronic Coronary Total Occlusion, Coronary Bypass Graft Stenosis
- Trial name
- CROSS (NCT01186198)
- Testing
- MINI TREK RX 1.20 mm Coronary Dilatation Catheter
- Where
- 4 sites in United States
- Volunteers
- 71 people
- Sponsor
- Abbott Medical Devices
Right Coronary Artery Percutaneous Coronary Intervention, Right Ventricular Diastolic Dysfunction
Diastolic RV EvAluation With Millar Catheter to Investigate the Effect of Glucagon-Like Peptide-1 (GLP-1) on Right Ventricular Function During Elective Coronary Angioplasty and Stenting
The heart requires nutrients and oxygen carried in the blood to generate energy for healthy pump function. Blood is supplied via heart vessels called coronary arteries.
- Trial name
- DREAM GLP-1 (NCT02236299)
- Testing
- Right Coronary Artery Percutaneous Coronary Intervention, GLP-1 Infusion
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Acute Coronary Syndrome, Percutaneous Transluminal Coronary Angioplasty
Establish a Telecare Model of Acute Coronary Syndrome Patient With Heart Stent Implantation by a Non-invasive Wearable Device and Artificial Intelligence Cloud to Reducing Medical Adverse Events.
Heart disease is still one of the world's most important health problems, and it ranks second among the top ten causes of death among Taiwan.
- Trial name
- NCT04455568
- Testing
- use EKG Wisdom bracelet
- Volunteers
- 400 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
ST-elevation Myocardial Infarction
Intracoronary Cocktail Injection Combined With Thrombus Aspiration in STEMI Patients Treated With Primary Angioplasty
This is a randomized, double blind, placebo controlled study of intracoronary cocktail injection combined with thrombus aspiration versus thrombus aspiration alone in ST-elevation myocardial infarction patients treated with…
- Trial name
- NCT02592694
- Testing
- cocktail, thrombus aspiration
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xijing Hospital
Coronary Artery Disease
Randomized Trial of Creatine-kinase Leak After Rosuvastatin At the Time of Percutaneous Coronary Intervention
Patients with stable coronary disease when undergoing percutaneous coronary intervention may present periprocedural myocardial infarction defined at present as a creatine kinase-myocardial isoenzyme (CK-MB) elevation 3 times…
- Trial name
- CLEAR-PCI (NCT01968577)
- Testing
- Rosuvastatin
- Where
- Brazil
- Volunteers
- 528 people
- Sponsor
- Kleber Bomfim Araujo Martins
Popliteal Arterial Stenosis
Drug-Eluting Balloons vs Mimetic Stents for Popliteal Artery Disease
More advanced and severe cases of chronic lower limb ischemia (the so-called critical lower limb ischemia) are painful and limiting conditions that impact on patients' quality of life.
- Trial name
- NCT05651165
- Testing
- Pharmacoactive balloon angioplasty. Lutonix®, Mimetic stent.Supera®
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Hospital Universitari de Bellvitge