Clinical trials: Coronary Angioplasty
Stroke, Coronary Artery Disease
Cerebral Artery Stenosis, Coronary Artery Disease and Arrhythmia
There are many reports about the association of coronary artery disease (CAD) and cerebral artery stenosis (CAS), which had been proved to induce stroke and cognition decline after the revascularization including coronary bypass…
- Conditions
- Stroke, Coronary Artery Disease, Arrhythmia
- Trial name
- NCT00247533
- Testing
- Digital subtraction angiography and 24-hour simultaneous recorder of electrocardiograph
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Far Eastern Memorial Hospital
Angina, Unstable, Angioplasty, Transluminal, Percutaneous Coronary
A Study Evaluating the Efficacy and Safety of Abciximab, an Anti-platelet Therapy, in Patients Undergoing High-risk Coronary Angioplasty
The purpose of this study is to evaluate the effectiveness and safety of abciximab (an anti-platelet therapy) versus placebo in patients undergoing high risk coronary angioplasty.
- Trial name
- NCT00269893
- Testing
- Abciximab
- Volunteers
- 2,038 people
- Sponsor
- Centocor, Inc.
Coronary Artery Disease
Optimal Strategy for Side Branch Stenting in Coronary Bifurcation Lesion
The purpose of this study is to establish the optimal strategy for side branch stenting in coronary bifurcation lesion.
- Trial name
- NCT00794014
- Testing
- Conservative strategy, Aggressive strategy
- Where
- South Korea
- Volunteers
- 258 people
- Sponsor
- Samsung Medical Center
Stent Thrombosis
Register of Patients Benefiting From a Coronary Bifurcation Angioplasty at the University Hospital of Nîmes and Montpellier in 2017
Cardiovascular diseases are the second leading cause of death in France and the world's leading cause.Coronary bifurcations are conducive to the development of atheromatous lesions due to flow turbulence generating a…
- Trial name
- Register (NCT04011046)
- Testing
- Stent
- Where
- France
- Volunteers
- 143 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Myocardial Ischemia, Coronary Disease
Efficacy of FX06 in the Prevention of Myocardial Reperfusion Injury
The purpose of the study is to evaluate whether FX06 is capable of limiting infarct size following balloon catheterization for acute myocardial infarction.
- Conditions
- Myocardial Ischemia, Coronary Disease, Myocardial Infarction
- Trial name
- NCT00326976
- Testing
- FX06, Percutaneous coronary intervention
- Where
- 32 sites in Austria, Belgium and 9 more
- Volunteers
- 234 people
- Sponsor
- Fibrex Medical Research & Development GmbH
Saphenous Vein Graft Atherosclerosis
Drug-Eluting Stents vs. Bare Metal Stents In Saphenous Vein Graft Angioplasty
Patients who have undergone coronary bypass surgery have had a vein removed from the leg and implanted in the chest to "bypass" blockages in the coronary arteries. These veins are called saphenous vein grafts or SVGs.
- Trial name
- DIVA (NCT01121224)
- Testing
- Bare Metal Stent, Drug-Eluting Stent, Blinded clopidogrel
- Where
- 25 sites in United States
- Volunteers
- 597 people
- Sponsor
- VA Office of Research and Development
Myocardial Infarction
Feedback Intervention and Treatment Times in ST- Elevation Myocardial Infarction
Part I (Pilot Phase): The purpose of this study is to examine if formalized data assessment and systematic feedback improves treatment times (i.e.
- Trial name
- FITT-STEMI (NCT00794001)
- Testing
- Data analysis and Feedback
- Where
- Germany
- Volunteers
- 50,000 people
- Sponsor
- Karl Heinrich Scholz
ST Elevation Myocardial Infarction
Impact of Glycemic State on Patients ST Elevation Myocardial Infarction With Primary Percutaneous Coronary Angioplasty
ST-elevation myocardial infarction is a major cause of morbidity and mortality worldwide. ST-elevation myocardial infarction damages the regional myocardium that undergoes ischemia and necrosis, resulting in impairment of both…
- Trial name
- NCT03266978
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Assiut University
Stable Angina, Unstable Angina Pectoris
Opsens Optowire for Fractional Flow Reserve - The O2 Pilot Study
The purpose of this study is to assess the usability and safety of the Opsens OptoWire and Optomonitor in measuring fractional flow reserve (FFR) in patients with coronary artery disease who are undergoing a coronary angiogram.
- Conditions
- Stable Angina, Unstable Angina Pectoris, Chest Pain, Ischemia
- Trial name
- O2 (NCT02144090)
- Testing
- Fractional flow reserve measurement
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Laval University
Aorto-ostial Coronary Lesions, Coronary Angioplasty
The OSTIAL Study (Optimization of Stent Placement in Aorto-ostial Lesions)
Aorto-ostial coronary lesions present a significant challenge during coronary angioplasty. This is due to the difficulty of precisely identifying the aorto-ostial plane and the frequent instability of the guiding catheter during…
- Conditions
- Aorto-ostial Coronary Lesions, Coronary Angioplasty, Floating Balloon" (FB) Technique
- Trial name
- OSTIAL (NCT07835048)
- Testing
- Coronary angioplasty using the floating balloon technique, Coronary angioplasty without the floating-balloon technique
- Where
- 6 sites in France
- Volunteers
- 75 people
- Sponsor
- Centre Cardiologique du Nord
Coronary Artery Disease
Safety of High-dose Tirofiban During Coronary Angioplasty
This single-centre study is intended to retrospectively check the safety of high-dose bolus of tirofiban in patients who underwent percutaneous angioplasty.
- Trial name
- SANTISS (NCT00566891)
- Testing
- tirofiban, Clopidogrel
- Where
- Italy
- Volunteers
- 2,000 people
- Sponsor
- S. Anna Hospital
Arterial Occlusive Diseases
The Study to Compare the Treatment of Angioplasty and Stents in SFA Occlusions.
The main objective of this study is to assess the patency rate of the nitinol self-expandable stent device in the treatment of superficial femoral artery (SFA) occlusions as compared to angioplasty only.
- Trial name
- DURAVEST (NCT00289055)
- Testing
- stent, angioplasty
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Cordis US Corp.
Lithotripsy, Angioplasty
Observatory on the Use of the Shockwave Medical C2 Coronary Lithotripsy System in the General Population in France.
Coronary calcified lesions will have an increasing impact in the daily practice of coronary angioplasty, considering the epidemiological explosion of factors favoring coronary calcifications, first of all diabetes.
- Conditions
- Lithotripsy, Angioplasty, Coronary Balloon
- Trial name
- France LILI (NCT05113407)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- French Cardiology Society
STEMI - ST Elevation Myocardial Infarction
Clinical Characteristics and Prognosis of STEMI Patients Undergoing Primary Percutaneous Coronary Angioplasty and Angiographic Data
Gensini score (GS) provides valuable information on severity and prognosis of coronary artery disease (CAD). We aim to evaluate the relationship between the severity of CAD determined by the GS and short and long term of…
- Trial name
- NCT05679843
- Volunteers
- 3,000 people
- Sponsor
- Central Hospital, Nancy, France
Coronary Artery Disease
Do Cobalt Chrome Stent and Paclitaxel-Eluting Stent Have Equivalent Clinical Result in Non-Complex Lesion?
We sought to evaluate the long-term safety and efficacy of drug-eluting stent in large vessels compared with bare metal stent.
- Trial name
- COPE (NCT00852215)
- Testing
- Taxus stent, Vision stent
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Samsung Medical Center
Bioresorbable Scaffolds
Performance of Bioabsorbable Vascular Scaffolds (Absorb) Compared to Xience Stents - an Optical Coherence Tomography Study
The biodegradable ABSORB scaffold is characterized by a greater strut thickness, but it has a greater flexibility compared to the XIENCE stent.
- Trial name
- NCT02001025
- Testing
- Absorb scaffold, Xience stent
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Rudolf Berger
Coronary Disease, Heart Diseases
Single vs. Dual Antiplatelet Therapy in Elderly or HBR Patients Undergoing Percutaneous Intervention With DCB (PICCOLETO IV-EPIC 38)
This international, multicenter, open-label, randomized clinical trial evaluates the safety and efficacy of single antiplatelet therapy (SAPT) compared to dual antiplatelet therapy (DAPT) in elderly or high bleeding risk patients…
- Conditions
- Coronary Disease, Heart Diseases, Cardiovascular Diseases, Myocardial Ischemia
- Trial name
- PIV-EPIC (NCT06535568)
- Testing
- Drug-coated balloon, Single antiplatelet therapy (SAPT), Dual antiplatelet therapy (DAPT)
- Where
- Italy
- Volunteers
- 576 people
- Sponsor
- Fondazione Ricerca e Innovazione Cardiovascolare ETS
Coronary Occlusion
Validation Of Quantitative Flow Ratio (QFR) - Derived Virtual Angioplasty
Prospective intervention study to assess the accuracy of the predicted QFR-derived virtual angioplasty compared to hyperaemic and non-hyperaemic pressure-wire derived indexes after PCI, as well as with QFR post-PCI.
- Trial name
- QIMERA-I (NCT04200469)
- Testing
- Quantitative Flow Ratio (QFR) measurement
- Where
- 5 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Clínico Universitario de Valladolid
Angioplasty, Transluminal, Percutaneous Coronary, Coronary Arteriosclerosis
Plug Arterial Closure System (PACS, 7F)
The purpose of this study is to assess the safety and feasibility of the 7F Ensure Medical Vascular Closure Devices to facilitate hemostasis in patients undergoing diagnostic or interventional coronary procedures using a standard…
- Trial name
- PACS 7F (NCT00533156)
- Testing
- Vascular access site closure (7F Ensure)
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Cordis US Corp.
Myocardial Infarction, Coronary Artery Disease
The Viability-Guided Angioplasty After Acute Myocardial Infarction-Trial (The VIAMI-Trial)
The VIAMI-trial investigates the effects of balloon angioplasty with stenting of the infarct-vessel in the early phase after acute myocardial infarction.
- Trial name
- NCT00149591
- Testing
- coronary balloon-angioplasty with stenting
- Where
- 12 sites in Netherlands
- Volunteers
- 300 people
- Sponsor
- Netherlands Heart Foundation