Clinical trials: Coronary Angioplasty
Peripheral Vascular Diseases
DEB ( Drug Eluting Balloon) in Crural Arteries and Critical Limb Ischemia
The purpose of this trial is to compare short- medium long-term results in treatment of PAD (peripheral arterial disease) in the crural arteries with either drug coated balloon or conventional balloons in a prospective …
- Trial name
- NCT02750605
- Testing
- DEB, POBA
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Skane University Hospital
Angioplasty, Transluminal, Percutaneous Coronary
Efficacy Study of Cilostazol Loading in Elective Percutaneous Coronary Intervention
The purpose of this study is to investigate the effect of cilostazol loading before planned PCI on major adverse cardiac and cerebrovascular events in patients with coronary artery disease.
- Trial name
- PRECEDE (NCT00938522)
- Testing
- Cilostazol
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Samsung Medical Center
Myocardial Reperfusion, Myocardial Infarction
Effects of Postconditioning On Myocardial Reperfusion
The purpose of this study is to investigate the effects of postconditioning on myocardial reperfusion in patients with ST-segment elevation myocardial infarction.
- Trial name
- POST (NCT00942500)
- Testing
- Post-conditioning
- Where
- South Korea
- Volunteers
- 700 people
- Sponsor
- Samsung Medical Center
Right Coronary Artery Percutaneous Coronary Intervention, Right Ventricular Diastolic Dysfunction
Diastolic RV EvAluation With Millar Catheter to Investigate the Effect of Glucagon-Like Peptide-1 (GLP-1) on Right Ventricular Function During Elective Coronary Angioplasty and Stenting
The heart requires nutrients and oxygen carried in the blood to generate energy for healthy pump function. Blood is supplied via heart vessels called coronary arteries.
- Trial name
- DREAM GLP-1 (NCT02236299)
- Testing
- Right Coronary Artery Percutaneous Coronary Intervention, GLP-1 Infusion
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Lithotripsy, Angioplasty
Observatory on the Use of the Shockwave Medical C2 Coronary Lithotripsy System in the General Population in France.
Coronary calcified lesions will have an increasing impact in the daily practice of coronary angioplasty, considering the epidemiological explosion of factors favoring coronary calcifications, first of all diabetes.
- Conditions
- Lithotripsy, Angioplasty, Coronary Balloon
- Trial name
- France LILI (NCT05113407)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- French Cardiology Society
Dialysis, Angioplasty
Drug Eluting Balloon Angioplasty for Dialysis Access Treatment
The aim of the study is to compare the feasibility and the effectiveness, by means of immediate and long-term results, of drug eluting balloon (DEB) versus conventional balloon angioplasty for the treatment of failing dialysis…
- Trial name
- NCT01174472
- Testing
- Percutaneous Transluminal Angioplasty (PTA)
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- University of Patras
Angina Pectoris, Acute Coronary Syndrome
Integrated Distance Management Strategy for Patients With Cardiovascular Diseases in the Context of COVID-19
Management of known patients with cardiovascular disease (in particular the whole spectrum of atherosclerotic ischaemic coronary artery disease, essential hypertension under treatment, and also patients with chronic heart failure…
- Conditions
- Angina Pectoris, Acute Coronary Syndrome, Coronary Syndrome, Coronary Artery Disease
- Trial name
- eCardioCovid19 (NCT04325867)
- Testing
- Tele-medicine platform
- Where
- 2 sites in Romania
- Volunteers
- 200 people
- Sponsor
- Professor Adrian Covic
Stable Angina Pectoris, Coronary Artery Disease
1 or 6 Months of Dual Antiplatelet Therapy After Drug-coated Balloon Angioplasty for De-novo Small Coronary Artery Disease
1. Objective Objective: > The purpose of this study is to evaluate whether a short-term (1-month) dual antiplatelet therapy (DAPT) followed by single antiplatelet therapy (SAPT) is non-inferior to the standard 6-month DAPT in…
- Trial name
- D-ONE (NCT07592507)
- Testing
- 1-Month DAPT followed by SAPT, 6-Month DAPT followed by SAPT
- Volunteers
- 1,484 people
- Sponsor
- Daejeon St. Mary's hospital
Stable Angina, Myocardial Infarction
Safety Evaluation of Clopidogrel Sulfate in Patients With Stable Angina/Old Myocardial Infarction to Whom Percutaneous Coronary Intervention is Being Planned
Primary objective: To evaluate whether 12 weeks of clopidogrel is superior to ticlopidine in terms of lower risk of the safety events of interest in patients with stable angina (SA) or old myocardial infarction (OMI) to which…
- Trial name
- CLEAN (NCT00821834)
- Testing
- clopidogrel (SR25990), ticlopidine
- Where
- Japan
- Volunteers
- 1,003 people
- Sponsor
- Sanofi
Acute Coronary Syndrome, Angioplasty, Transluminal, Percutaneous Coronary
Early Use of Rosuvastatin in Acute Coronary Syndromes: Targeting Platelet-Leukocyte Interactions
The central hypothesis for this work is that platelet - leukocyte interactions play a critical role in the pathogenesis of acute ischemic events.
- Conditions
- Acute Coronary Syndrome, Angioplasty, Transluminal, Percutaneous Coronary, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Blood Platelets
- Trial name
- NCT01241903
- Testing
- rosuvastatin
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Susan Smyth
Coronary Disease
Mechanism of Percutaneous Revascularization for Coronary Bifurcation Disease
The main objectives of this study are define frequency of plaque shift phenomenon and impact on flow dynamics in the side branch as assessed by intravascular ultrasound, and evaluate acute and late side branch ostial vessel…
- Trial name
- NCT00429052
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Florida
ST-elevation Myocardial Infarction
Primary Reperfusion Secondary Stenting Trial
The purpose of this research project is to improve how we treat heart attacks. The study will assess whether it might not be better to wait a few hours before implanting the coronary stent into the coronary artery rather than…
- Trial name
- PRIMACY (NCT01542385)
- Testing
- Stent
- Where
- 16 sites in Canada, France
- Volunteers
- 307 people
- Sponsor
- Montreal Heart Institute
Arteriovenous Fistula Stenosis
The SIR-POBA Shunt Trial
The goal of this clinical trial is to compare plain old balloon angioplasty with sirolimus-coated balloon angioplasty in patients with an arteriovenous shunt stenosis.
- Trial name
- NCT06056206
- Testing
- Balloon Angioplasty
- Where
- Austria
- Sponsor
- Paracelsus Medical University
Radial Artery Spasm
Nitrate Use to Obtain Radial Spasm Embarrassment (NURSE - TTS Trial)
Transradial cardiac catheterization and percutaneous coronary intervention are increasingly being performed worldwide in elective and emergency procedures, with many centres adopting the transradial route as their first choice of…
- Trial name
- NURSE-TTS (NCT04766151)
- Testing
- Transdermal glyceryl trinitrate 10mg patches
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- 424 General Military Hospital
Myocardial Ischemia, Coronary Disease
Efficacy of FX06 in the Prevention of Myocardial Reperfusion Injury
The purpose of the study is to evaluate whether FX06 is capable of limiting infarct size following balloon catheterization for acute myocardial infarction.
- Conditions
- Myocardial Ischemia, Coronary Disease, Myocardial Infarction
- Trial name
- NCT00326976
- Testing
- FX06, Percutaneous coronary intervention
- Where
- 32 sites in Austria, Belgium and 9 more
- Volunteers
- 234 people
- Sponsor
- Fibrex Medical Research & Development GmbH
Coronary Arteriosclerosis, Angina Pectoris
Randomized Comparison Angioplasty Outcomes at Hospitals With and Without On-site Cardiac Surgery
Angioplasty is a procedure which opens blocked heart arteries using balloons and/or stents. Most U.S. states and all national heart organizations require that angioplasty be done only at hospitals that can also perform open heart…
- Trial name
- NCT00549796
- Testing
- Percutaneous coronary intervention (PCI)
- Where
- 60 sites in United States
- Volunteers
- 18,876 people
- Sponsor
- Johns Hopkins University
Chronic Total Occlusion
Use of Drug-Coated Balloon to Improve Recanalization of a Coronary Chronic Total Occlusion After Failed Angioplasty
Observational retrospective registry to compare effectiveness of paclitaxel-coated vs. non coated balloon angioplasty proximal to a Chronic Total Occlussion (CTO) after failed revascularization.
- Trial name
- IMPROVED-RECTO (NCT05158686)
- Testing
- Paclitaxel-coated Balloon dilation angioplasty, Non-coated Balloon dilation angioplasty
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Ignacio J. Amat Santos
Peripheral Vascular Disease
Standard Balloon Angioplasty Versus Angioplasty With a Paclitaxel-eluting Balloon for Femoral Artery In-stent Restenosis
Comparison of recurrent-restenosis rates 6 months after angioplasty of in-stent restenoses or in-stent reocclusions in the superficial femoral artery (SFA) using either a standard balloon (Admiral Xtreme, Invatec) or a…
- Trial name
- FAIR (NCT01305070)
- Testing
- Admiral Xtreme, In.Pact Admiral
- Where
- Germany
- Volunteers
- 118 people
- Sponsor
- Medical Care Center Prof. Mathey, Prof. Schofer, Ltd.
Critical Limb Ischemia
Lutonix DCB Versus Standard Balloon Angioplasty for Treatment of Below-The-Knee (BTK) Arteries
To assess the safety and efficacy of the Lutonix Drug Coated Balloon (DCB) for treatment of stenosis or occlusion of native below-the-knee arteries.
- Trial name
- NCT01870401
- Testing
- Lutonix DCB, Uncoated PTA Catheter
- Where
- 51 sites in United States, Austria and 6 more
- Volunteers
- 442 people
- Sponsor
- C. R. Bard
Anterior Wall Acute Myocardial Infarction
Evaluation of the Delivery of Optimized Supersaturated Oxygen Therapy to Treat Patients With an Acute Heart Attack
The purpose of this study is to evaluate the feasibility of the delivery of SuperSaturated Oxygen (SSO2) Therapy for 60 minutes selectively into the left main coronary artery (LMCA).
- Trial name
- NCT01630707
- Testing
- SuperSaturated Oxygen (SS02) Therapy
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- TherOx