Clinical trials: Coronary Angioplasty
Arteriosclerosis, Peripheral Artery Disease
Durg Coated Balloon Angioplasty in Infrapopliteal Lesions
This study is a multicenter observational study designed to evaluate the the effectiveness and safety of drug-coated balloon (DCB) angioplasty for below the knee arterial lesions in patients critical with Limb Threatening…
- Conditions
- Arteriosclerosis, Peripheral Artery Disease, Chronic Limb Threatening Ischemia
- Trial name
- Act (NCT05620095)
- Testing
- drug-coated balloon
- Where
- 10 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Liyuan Hospital of Tongji Medical College, Huazhong University of Science and Technology
ST Elevation Myocardial Infarction, Coronary Stenting
Revascularization StrategIes for ST Elevation Myocardial Infarction Trial
This study is being conducted in patients with a major heart attack caused by a blocked artery undergoing Percutaneous Coronary Intervention (PCI) to open up the blockage.
- Conditions
- ST Elevation Myocardial Infarction, Coronary Stenting, Primary Angioplasty
- Trial name
- ASSIST-MI (NCT03263468)
- Testing
- Same sitting PCI with complete revascularization, Staged PCI with complete revsacularization >48 hours pf primary PCI
- Volunteers
- 3,520 people
- Sponsor
- Unity Health Toronto
Coronary Heart Disease, Angioplasty, Balloon
The Clinical Efficacy and Safety of Drug-coated Balloon
Drug-Coated Balloon (DCB) angioplasty is similar to plain old balloon angioplasty procedurally, but there is an anti-proliferative medication paclitaxel coated on the balloon.
- Trial name
- NCT05133921
- Where
- China
- Volunteers
- 2,487 people
- Sponsor
- Xijing Hospital
Peripheral Vascular Disease
Tack Optimized Balloon Angioplasty (TOBA) Study
A multi-center, post-CE Mark study designed to evaluate the performance of the Intact Vascular Tack-IT Endovascular Stapler™ in subjects with vascular flaps (e.g.; post-angioplasty dissection) resulting from percutaneous…
- Trial name
- TOBA (NCT01663818)
- Testing
- Tack-It Endovascular Stapler
- Where
- Belgium
- Volunteers
- 138 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Myocardial Infarction
Myocardial Oedema in Acute Myocardial Infarction (AMI)
Despite recent improvements in treatment, myocardial infarction (heart attack) is still a leading cause of illness and death in the UK.
- Trial name
- NCT00987259
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Barts & The London NHS Trust
Coronary Occlusion, Angioplasty, Balloon, Coronary
Functional Assessment-guided Angioplasty in Patients With Coronary Chronic Total Occlusion
The aim of this study is to investigate the role of functional evaluation for predicting clinical outcome in patients with coronary chronic total occlusion (CTO) undergoing percutaneous coronary intervention (PCI), and to…
- Trial name
- FAGA-CTO (NCT03522038)
- Testing
- percutaneous coronary intervention
- Volunteers
- 300 people
- Sponsor
- Shanghai Zhongshan Hospital
Coronary Disease, Cardiovascular Diseases
Bypass Angioplasty Revascularization Investigation in Type 2 Diabetes
The BARI 2D trial is a multicenter study that uses a 2x2 factorial design, with 2400 patients being assigned at random to initial elective revascularization with aggressive medical therapy or aggressive medical therapy alone with…
- Conditions
- Coronary Disease, Cardiovascular Diseases, Heart Diseases, Insulin Resistance
- Trial name
- BARI2D (NCT00006305)
- Testing
- Angioplasty, Transluminal, Percutaneous Coronary, other catheter-based interventions, Coronary Artery Bypass, Biguanides, thiazolidinediones
- Volunteers
- 2,368 people
- Sponsor
- University of Pittsburgh
Coronary Artery Calcification, Angioplasty
CAlcified Lesion Intervention Planning Steered by OCT.
Calcified lesions are very frequent among coronary artery disease stenotic lesions. The prevalence of calcifications ranges from 30 to 40% (by angiography evaluation) but is higher when analyzed by intra coronary imaging.
- Trial name
- CALIPSO (NCT05301218)
- Testing
- angioplasty
- Where
- 14 sites in France
- Volunteers
- 140 people
- Sponsor
- Institut Mutualiste Montsouris
Stable Angina, Unstable Angina Pectoris
Opsens Optowire for Fractional Flow Reserve - The O2 Pilot Study
The purpose of this study is to assess the usability and safety of the Opsens OptoWire and Optomonitor in measuring fractional flow reserve (FFR) in patients with coronary artery disease who are undergoing a coronary angiogram.
- Conditions
- Stable Angina, Unstable Angina Pectoris, Chest Pain, Ischemia
- Trial name
- O2 (NCT02144090)
- Testing
- Fractional flow reserve measurement
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Laval University
Critical Limb Ischemia
Serrantor OCT Study
TA prospective randomized control trial to evaluate the serration angioplasty effect in BTK arteries with varying degrees of calcified plaque.
- Trial name
- NCT06434194
- Testing
- Serranator PTA Serration Catheter, PTA (Standard of Care)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Cagent Vascular LLC
Heart Disease, Ischemia
Efficacy Study of Paclitaxel-eluting Balloon, -Stent vs. Plain Angioplasty for Drug-eluting Stent Restenosis
The purpose of this randomized study is to determine which treatment option, either paclitaxel-eluting balloon, paclitaxel-eluting stent or plain balloon angioplasty is the most effective in the treatment of restenosis after…
- Conditions
- Heart Disease, Ischemia, Restenosis
- Trial name
- ISAR-DESIRE-3 (NCT00987324)
- Testing
- Taxus stent, SeQuent Please, Conventional Balloon Catheter
- Where
- 3 sites in Germany
- Volunteers
- 402 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Ischemic Cardiomyopathy
Effect of Smoking on Activated Clotting Time Values During Coronarography and Angioplasty
analyzing influence of smoking on patients anti-coagulation status as assessed by ACT measurements during coronary angioplasty
- Trial name
- NCT04897997
- Testing
- coronarography and angioplasty
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Central Hospital, Nancy, France
Peripheral Arterial Diseases
Comparing Angioplasty and DES in the Treatment of Subjects With Ischemic Infrapopliteal Arterial Disease
The primary objective of this study is to compare the performance of the CYPHER SELECTTM + Sirolimus-eluting Balloon-expandable Coronary and Infrapopliteal Stent over balloon angioplasty in de novo and restenotic native below the…
- Trial name
- ACHILLES (NCT00640770)
- Testing
- balloon angioplasty, drug eluting stent
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Cordis US Corp.
Angioplasty, Coronary Angiography
Analysis of Hospitalizations One Year After Acts of CAG and PCI in the Aquitaine région - ACIRA Register Data Analysis
Hospital readmission rate following percutaneous coronary interventions (PCI) or coronary angiographies (CAG) is a main indicator of quality of care and addresses economic issues.
- Trial name
- ACIRA-REHOSP (NCT03115723)
- Testing
- Percutaneous coronary intervention, Coronary angiography
- Where
- 11 sites in France
- Volunteers
- 11,487 people
- Sponsor
- University Hospital, Bordeaux
Arterial Occlusive Diseases
The Study to Compare the Treatment of Angioplasty and Stents in SFA Occlusions.
The main objective of this study is to assess the patency rate of the nitinol self-expandable stent device in the treatment of superficial femoral artery (SFA) occlusions as compared to angioplasty only.
- Trial name
- DURAVEST (NCT00289055)
- Testing
- stent, angioplasty
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Cordis US Corp.
Heart Diseases, Heart Failure
Mindfulness & Stress Management Study for Cardiac Patients
The guideline-recommended standard of care for patients who have experienced a heart attack, heart failure, or other coronary event or procedure is exercise-based cardiac rehabilitation (CR).
- Conditions
- Heart Diseases, Heart Failure, Myocardial Infarction, Chronic Stable Angina
- Trial name
- NCT02722213
- Testing
- Mindfulness-Based Stress Reduction (MBSR).
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Minnesota
Peripheral Arterial Disease, Intermittent Claudication
Systematic Review and Meta-Analysis on DCB vs. POBA in De-novo Femoropopliteal Disease
Restenosis is still an issue after endovascular revascularization for femoropopliteal occlusive disease. One approach to reduce the rates of restenosis and reintervention is local application of Paclitaxel with drug-coated…
- Trial name
- DOND (NCT02927574)
- Testing
- DCB, POBA
- Volunteers
- 1,400 people
- Sponsor
- Jena University Hospital
Chronic Coronary Occlusion, Left Main Coronary Artery Disease
EXCEL Clinical Trial (Universal Registry)
The purpose of the Universal Registry is to assess the proportion and reasons for which subjects with angiographically significant ULMCA disease requiring revascularization during the time course of this study are not randomized…
- Conditions
- Chronic Coronary Occlusion, Left Main Coronary Artery Disease, Stent Thrombosis, Vascular Disease
- Trial name
- EXCEL (NCT01205789)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Abbott Medical Devices
ST-segment Elevation Myocardial Infarction
Henan STEMI Registry
ST-segment elevation myocardial infarction (STEMI) remains among the most acute and critical diseases, with primary percutaneous coronary intervention (pPCI) and thrombolysis as mainstay reperfusion treatments.
- Trial name
- NCT02641262
- Where
- China
- Volunteers
- 5,479 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Vertebral Artery Stenosis
Drug-coated Balloon Angioplasty for Patients With Symptomatic Vertebral Artery Stenosis
Posterior circulation stroke accounts for 20% of ischemic stroke. A quarter occurs in patients with stenosis in the vertebral and/or basilar arteries. Vertebral artery stenosis can be treated with stenting.
- Trial name
- NCT03504657
- Testing
- Drug-coated balloon angioplasty, stenting angioplasty
- Where
- 2 sites in China
- Volunteers
- 150 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University