Clinical trials: Coronary Arterioscleroses
Cardiovascular; Attack
Very Early Versus Delayed Angiography +/- Intervention on Outcomes in Patients With NSTEMI
Prospective, open, multicentre, randomised controlled trial in patients with higher risk non-ST elevation myocardial infarction acute coronary syndrome
- Trial name
- RapidNSTEMI (NCT03707314)
- Testing
- Angiography with follow-on revascularisation if indicated
- Where
- United Kingdom
- Volunteers
- 425 people
- Sponsor
- University Hospitals, Leicester
Coronary Heart Disease, NSTEMI
Bare Metal Stent Versus Drug Coated Balloon With Provisional Stenting in Non-ST-Elevation Myocardial Infarction
The aim of the present trial is to assess the efficacy of the standalone use of SeQuent(R) Please coated balloon compared to a bare metal stent (BMS) in patients with NSTEMI.
- Trial name
- PEPCADNSTEMI (NCT01489449)
- Testing
- Stent, SeQuent(R) Please coated balloon
- Where
- Germany
- Volunteers
- 210 people
- Sponsor
- University Hospital, Saarland
Coronary Artery Disease, Chronic Kidney Diseases
Intravascular Ultrasound-Guided PCI in Patients With Chronic Kidney Disease
The IVUS-CKD study is a prospective, randomized controlled, multicenter trial to determine whether the intravascular ultrasound (IVUS)-guided percutaneous coronary intervention is superior to the angiography-guidance in chronic…
- Trial name
- IVUS-CKD (NCT06567938)
- Testing
- Percutaneous coronary intervention
- Where
- China
- Volunteers
- 1,528 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Coronary Artery Disease
PRV-based Detection of CAD in Comparison to Standard Methods
This is a validation study comparing a pulse wave based algorithm for the detection of coronary artery disease with parameters from coronary angiography, echocardiography and cardiogoniometry.
- Trial name
- PRV-KORO (NCT02404948)
- Testing
- Diagnostic algorithm
- Where
- Germany
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Coronary Artery Disease, Coronary Occlusion
Coronary CTO PCI Using Antegrade Wiring Strategy With a First-choice Gladius Guidewire (Gladius First)
The Gladius First trial is designed as a single-centre, open, prospective, randomized clinical trial aimed to assess the efficiency and safety of coronary chronic total occlusion (CTO) percutaneous coronary intervention (PCI)…
- Conditions
- Coronary Artery Disease, Coronary Occlusion, Percutaneous Coronary Intervention
- Trial name
- Gladius First (NCT04691778)
- Testing
- CTO PCI with the first-choice Gladius guidewire, CTO PCI without the first-choice Gladius guidewire
- Where
- Poland
- Volunteers
- 69 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Arteriosclerosis
Mindfulness-Based Stress Reduction and Myocardial Ischemia
The principal objective of the study is to evaluate the effectiveness of a widely used complementary medicine intervention, mindfulness-based stress reduction (MBSR), in which mindfulness meditation and yoga are the principal…
- Trial name
- NCT00224835
- Testing
- Mindfulness Based Stress Reduction Class, Cardiac Education Class
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Florida
STEMI
Effect of Covid-19 Epidemic on Primary PCI in Patients With STEMI
The epidemic of covid-19 has spread all over the world and has a great impact on people's health and life. It is necessary to study the treatment of STEMI patients in the real world under the influence of the epidemic,which…
- Trial name
- NCT04427735
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Friendship Hospital
Coronary Artery Disease, Chronic Total Occlusion
CTO-PCI in Heart Failure Patients
The study investigates wheather CTO-PCI improves survival and heart failure related rehospitalization compared to optimal medical therapy (OMT).
- Conditions
- Coronary Artery Disease, Chronic Total Occlusion, Heart Failure
- Trial name
- CTO-HF (NCT05632653)
- Testing
- CTO-PCI
- Volunteers
- 783 people
- Sponsor
- Universitätsmedizin Mannheim
Angina Pectoris, Ischemic Heart Disease
Heart Rate Variability (HRV) Testing Compared With Exercise Stress Test in Hospitalized Patients With Chest Pain
There are many patients hospitalized for chest pain, which don't have high risk features that require invasive coronary angiography, but are considered intermediate risk and for which ischemic heart disease can not be excluded.
- Trial name
- NCT02530021
- Testing
- Heart rate monitor
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Meir Medical Center
Hypoglycemia, Type 2 Diabetes
Hypoglycemia (Low Blood Sugar) and the Heart
The risk of hypoglycemia (low blood sugar) associated with the treatment of diabetes increases with age. Hypoglycemia is a common reason for admission to hospital for older patients with diabetes.
- Trial name
- NCT01980914
- Testing
- iPro2 glucose sensor attachment
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- University of British Columbia
Stable Angina Pectoris
Quality of Life and Target Achievement After Treatment of Patients With Stable Angina Pectoris
The purpose of this study is to, in patients with stable angina pectoris, assess the additional benefit of PCI on top of optimized medical treatment, physical training and smoking cessation with regard to quality of life…
- Trial name
- LOBSTR (NCT00825604)
- Testing
- Percutaneous coronary angioplasty (PCI)
- Where
- Sweden
- Sponsor
- Göteborg University
Coronary Heart Disease
CTCA Prior to Invasive Angiography in Post-Bypass Patients (BYPASS CTCA 2)
The goal of this clinical trial is to evaluate whether a coronary computed tomography angiography (CTCA)-guided strategy can reduce the risk of death, heart attack, stroke, and hospital admissions in patients experiencing angina…
- Trial name
- NCT07165678
- Testing
- CTCA
- Where
- United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- Queen Mary University of London
CaIMR, Prognosis
The Usefulness of CaIMR in Patients With STEMI
The coronary artery system is composed of three different types of blood vessels, namely epicardial arteries, arterioles and capillaries.
- Conditions
- CaIMR, Prognosis, ST-segment Elevation Myocardial Infarction
- Trial name
- NCT04984915
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Zhongnan Hospital
Chronic Stable Angina, Periprocedural Myocardial Damage
MYocardial DAmage AND MIcrobiota STUDY
MYDA-MI study is a randomized, placebo controlled, double blind study performed in San Filippo Neri Hospital, Roma, Italy. The planned study duration is 18 months.
- Trial name
- MYDA-MI (NCT02908776)
- Testing
- Probiotic
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- San Filippo Neri General Hospital
Coronary Artery Disease, Anesthesia
Xenon in Off-pump Coronary Artery Bypass Graft Surgery
Purpose of this study is to test whether xenon application during off-pump-coronary artery bypass (OPCAB)-surgery is safe and feasible.
- Trial name
- NCT01757106
- Testing
- Xenon, sevoflurane
- Where
- Belgium
- Volunteers
- 42 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Coronary Artery Disease, Heart Diseases
Randomization of Single vs Multiple Arterial Grafts
The primary hypothesis of ROMA is that in patients undergoing primary isolated non-emergent coronary artery bypass surgery (CABG), the use of two or more arterial grafts compared to a single arterial graft is associated with a…
- Trial name
- ROMA (NCT03217006)
- Testing
- Single arterial graft, Multiple arterial grafting
- Where
- 59 sites in United States, Austria and 15 more
- Volunteers
- 4,300 people
- Sponsor
- Weill Medical College of Cornell University
Acute Myocardial Infarction
Thrombus Aspiration in Myocardial Infarction
Treatment of myocardial infarction (blood clot in the arteries of the heart) has improved after introduction of 24/7 balloon angioplasty to open the blocked artery.
- Trial name
- TASTE (NCT01093404)
- Testing
- Thrombus aspiration
- Where
- 29 sites in Denmark, Iceland and 1 more
- Volunteers
- 7,243 people
- Sponsor
- Region Örebro County
Acute Coronary Syndrome
Paradigm Shift in the Treatment of Patients With ACS
This protocol describes a pilot study intended to test the hypothesis that patients with acute coronary syndrome (ACS) caused by plaque erosion can be stabilized by effective antithrombotic treatment without stent implantation…
- Trial name
- NCT02041650
- Testing
- Ticagrelor
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Yu Bo
Acute Coronary Syndrome
PLIN1 Variants in Precocious ACS (SCAPLIN)
This study aims to identify a genetic predisposition factor of precocious acute coronary syndrome occurrence (ACS). ACS is a major public health problem and the first cause of mortality in the world.
- Trial name
- NCT04904432
- Testing
- PLIN1 gene sequencing
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Cardiovascular Diseases, Heart Diseases
Physicians' Health Study: Study of Low Cardiovascular Disease Mortality
To explain the extremely low cardiovascular mortality among Physicians' Health Study (PHS) participants by ascertaining all cardiovascular and total deaths among the 90,457 physicians who returned enrollment forms but were not…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Myocardial Infarction
- Trial name
- NCT00005252
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
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