Clinical trials: Coronary Arterioscleroses
Coronary Artery Disease
Comparison of Low-radiation Dose CT Angiography With Invasive Coronary Angiography in Stable Coronary Disease
This study is evaluating the performance of modern CT coronar angiography with low radiation technique compared to conventional invasive coronar angiography.
- Trial name
- NCT01476579
- Testing
- Cardiac Computer Tomography
- Where
- Norway
- Volunteers
- 769 people
- Sponsor
- University Hospital of North Norway
Coronary Disease, Aortic Valve Stenosis
Quantitative Measurement of Myocardial Perfusion by Cardiac CT in Patients
It is a common understanding that patients with coronary heart disease are suffering, among others, from reduced myocardial perfusion.
- Trial name
- CCT/MPERF (NCT02361996)
- Where
- 3 sites in Austria, Russia and 1 more
- Volunteers
- 690 people
- Sponsor
- Bakulev Scientific Center of Cardiovascular Surgery
Myocardial Infarction, Cerebral Infarction
Acute Myocardial Infarction and Acute Cerebral Infarction (AMIAC) Registry and Follow-up
A registry of consecutive patients who were admitted and diagnosed with acute myocardial infarction or acute cerebral infarction were conducted at the Guangdong General Hospital or the First Affiliated Hospital of Guangzhou…
- Conditions
- Myocardial Infarction, Cerebral Infarction, Chronic Kidney Diseases, Mortality
- Trial name
- AMIAC (NCT03166696)
- Where
- 3 sites in China
- Volunteers
- 30,000 people
- Sponsor
- Guangdong Provincial People's Hospital
Atrial Fibrillation
Coronary Computed Tomography AngioGraphy Prior to Catheter Ablation in Patients With Atrial FIBrillation
The purpose of this randomized, controlled trial is to investigate whether coronary computed tomography (CT) angiography prior to catheter ablation and derived treatment (medical anti-ischemic and multimodality treatment and/or…
- Trial name
- FIBCAG (NCT05978388)
- Testing
- Analysis of coronary CT Angiography and CAC scoring at the time of catheter ablation
- Where
- Denmark
- Volunteers
- 852 people
- Sponsor
- Tor Biering-Sørensen
Hypertension (HTN), Ischemic Heart Disease
Video Education to Improve Blood Pressure Control in Patients With Ischemic Heart Disease and Hypertension (V-EDUCATE)
We investigated whether video-based education using deepfake technology could improve blood pressure measurement adherence and medication adherence in patients with ischemic heart disease accompanied by hypertension.
- Trial name
- V-EDUCATE (NCT07210073)
- Testing
- Video Education, Control
- Where
- South Korea
- Volunteers
- 218 people
- Sponsor
- Keimyung University Dongsan Medical Center
Acute Myocardial Infarction With ST Elevation
Effect of Glp-1 and Antidiabetic sgLT2 Agents for myoCardial infarcTion and Ultrasensitive Inflammatory Surveillance (GALACTUS Trial)
The primary risk factor for coronary artery disease is atherosclerosis, with inflammation playing a crucial role in the development and progression of this condition.
- Trial name
- GALACTUS (NCT07295223)
- Testing
- Dapagliflozin 10 MG Oral Tablet, Semaglutide (Rybelsus®)
- Where
- Mexico
- Volunteers
- 44 people
- Sponsor
- Instituto Mexicano del Seguro Social
Acute Coronary Syndrome, NSTEMI - Non-ST Segment Elevation MI
Safety of Accelerated Rule-out Protocols in Patients Admitted With Chest Pain to a Crowded Chest Pain Unit (CPU)
The aim of this observational study registry is to assess the safety of a Non-ST-elevation myocardial infarction (STEMI) rapid rule-out strategy as proposed by European Guidelines in patients presenting with suspected acute…
- Trial name
- NCT03111862
- Testing
- NSTEMI Rule-Out according to hs-TnT
- Where
- Germany
- Volunteers
- 3,567 people
- Sponsor
- University Hospital Heidelberg
Cardiac Ischemia, Coronary Artery Disease
Radiographic Imaging Validation and EvALuation for Angio iFR (ReVEAL iFR)
The Philips Angio-iFR medical software device is intended to provide information on the functional significance of a coronary artery lesion to provide guidance on diagnostic decisions similar to that obtained through invasive…
- Conditions
- Cardiac Ischemia, Coronary Artery Disease, Coronary Stenosis
- Trial name
- ReVEAL (NCT03857503)
- Testing
- iFR
- Where
- 40 sites in United States, Germany and 5 more
- Volunteers
- 441 people
- Sponsor
- Volcano Corporation
Stable Angina
Outcome of Coronary High Angulated Bifurcation Lesions Treated With Kissing Ballooning or Sequential Ballooning Techniques
Coronary artery bifurcation lesions prone to occur with the worsening of atherosclerosis. Their structural properties make angioplasty technique to increase the difficulty of implementation, but also increased the risks of the…
- Trial name
- MV:main branch (NCT02137486)
- Where
- Taiwan
- Volunteers
- 214 people
- Sponsor
- Taipei City Hospital
Coronary Artery Disease
Prasugrel Re-load Strategies
A higher degree of platelet inhibition remains the goal of peri-interventional and long-term anti-thrombotic therapy in patients with coronary artery disease.
- Trial name
- NCT01201772
- Testing
- Prasugrel
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Florida
Acute Coronary Syndrome
Assessment of Biomarkers for Diagnosis in Geriatric Patients
Elderly patients are often admitted to hospital because of chest pain that is atypical for angina pectoris. In case of inconclusive electrocardiograms, determination of troponin is important for the diagnosis of an acute coronary…
- Trial name
- BOSCH1 (NCT01370395)
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Ischemic Heart Disease
Vegetarian Diet in Patients With Ischemic Heart Disease
Open label, 4 week randomized, cross-over study to compare the effect of a vegetarian diet to a conventional (meat containing) diet based on the Swedish average meat consumption on a range of parameters with prognostic importance…
- Trial name
- VERDI (NCT02942628)
- Testing
- Vegetarian diet followed by meat diet or vice versa
- Where
- Sweden
- Volunteers
- 31 people
- Sponsor
- Region Örebro County
Atherosclerosis, Acute-Phase Reaction
Erythrocyte-Mediated Drug Delivery for the Prevention of Stent Restenosis
The purpose of this study is to determine whether erythrocyte mediated dexamethasone delivery reduces circulating inflammatory markers after coronary stent implantation and improves clinical and angiographic outcomes.
- Trial name
- TROY (NCT00484965)
- Testing
- Coronary stenting
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Rome Tor Vergata
Myocardial Infarction
Genetic Variation in Platelet Aggregation
The aim of the study is to test whether genetic variation in the alpha 2A adrenergic receptor affects diurnal variation in platelet aggregation.
- Trial name
- NCT01576536
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Sudden Cardiac Death, Acute Myocardial Infarction
Thrombus and Inflammation Study in Sudden Cardiac DEath
Sudden death is a natural death occurring within one hour after the onset of symptoms. It remains a major public health problem and accounts for 5 to 10 % of the annual total mortality ie about 300.000 in the United States.
- Trial name
- TIDE (NCT00748111)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 380 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Myocardial Infarction
Acute Myocardial Infarction by Penetrating Cardiac Trauma
Patients with a cardiac stab wound could be complicated by a posttraumatic acute myocardial infarction (PAMI). Traditionally, the investigators can explain it by the occlusion of a coronary artery; but the PAMI isn´t constantly…
- Trial name
- NCT01182064
- Where
- Colombia
- Volunteers
- 51 people
- Sponsor
- Universidad de Antioquia
Coronary Artery Disease, Atherosclerosis
Nitrite Effects on Cardiac Muscle in CABG
The purpose of this study is to test whether sodium nitrite affects the expression of cellular proteins important for metabolic and vascular function in vascular offcuts and cardiac biopsies taken from patients undergoing…
- Conditions
- Coronary Artery Disease, Atherosclerosis, Vascular Diseases, Cardiac Disease
- Trial name
- NCT04001283
- Testing
- Sodium Nitrite, 0.9% Sodium-chloride
- Where
- 2 sites in United Kingdom
- Volunteers
- 75 people
- Sponsor
- University of East Anglia
Kawasaki Disease, Pilot Study
Model-informed Dose Optimization for Rivaroxaban in Children With Giant Coronary Artery Aneurysm After Kawasaki Disease
Based on a population pharmacokinetic model-based dose optimization study, a 15 mg-equivalent, age-, and bodyweight-adjusted dosing regimen for Chinese children with giant coronary artery aneurysms after Kawasaki disease was…
- Conditions
- Kawasaki Disease, Pilot Study, Coronary Artery Aneurysm, Rivaroxaban
- Trial name
- NCT06978439
- Testing
- Rivaroxaban (Xarelto)
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Fudan University
Myocardial Infarction
Abciximab i.v. Versus i.c. in Primary PCI Patients With STEMI
Randomized comparison of abciximab i.v. versus i.c. in patients with STEMI undergoing primary PCI. The hypothesis is, that higher concentration of abciximab i.c.
- Trial name
- NCT00299377
- Testing
- Abciximab i.v., Abciximab i.c.
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- University of Leipzig
Cardiovascular Diseases, Coronary Disease
Neighborhoods and CVD Risk in a Multiethnic Cohort - Ancillary to MESA
To investigate if neighborhood characteristics are related to disease risk in a multiethnic cohort.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Atherosclerosis
- Trial name
- NCT00063557
- Sponsor
- University of Michigan
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