Clinical trials: Coronary Arterioscleroses
Non-ST-segment Elevation Myocardial Infarction, Chronic Kidney Disease
Optimised Procedure in Patients With NSTEMI and CKD
Aim of the study is the determination of the ideal timepoint for the treatment of patients with acute Non-ST-segment Elevation Myocardial Infarction (NSTEMI) and an acute or chronic kidney disease (CKD) with a GRACE score < 140.
- Trial name
- NSTEMI-CKD (NCT02543177)
- Testing
- coronary angiography, ischemic precondition, prior kidney irrigation
- Where
- Germany
- Volunteers
- 1 people
- Sponsor
- RWTH Aachen University
Refractory Angina
Allopurinol in Patients With Refractory Angina to Improve Ischemic Symptoms
Despite numerous advances in medical treatment and revascularization procedures for the treatment of patients with stable angina, debilitating symptoms that are unresponsive to conventional therapy may occur in patients…
- Trial name
- ARAMIS (NCT04368819)
- Testing
- Allopurinol 300 MG
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Ministry of Health, Brazil
Coronary Artery Disease
The Effect of a Healthy Diet Containing Flaxseed and Olive Oil on Cardiovascular Disease Risk Markers
Flaxseed and olive oil consumption have beneficial effects on cardiovascular risk factors. Nonetheless the effects of their simultaneous consumption have not yet been studied.The purpose of this study is to investigate the…
- Trial name
- NCT04767230
- Testing
- Dietary Intervention
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Myocardial Infarction
Postconditioning in ST-elevation Myocardial Infarction
Study objectives: To assess the effects of postconditioning on infarct size in patients with ST-elevation infarction referred to PCI. Study design: Prospective, randomized, open-label study with blinded endpoint evaluation.
- Trial name
- POSTEMI (NCT00922675)
- Testing
- Postconditioning, Control intervention
- Where
- Norway
- Volunteers
- 272 people
- Sponsor
- Oslo University Hospital
Type 2 Diabetes Mellitus
Detection of Ischemia in Asymptomatic Diabetics
Asymptomatic subjects with Type 2 Diabetes Mellitus were randomized to either screening with Tc-99m sestamibi adenosine SPECT imaging or no screening.
- Trial name
- DIAD (NCT00769275)
- Where
- United States
- Volunteers
- 1,123 people
- Sponsor
- Yale University
Coronary Artery Disease, Ascending Aortic Aneurysm
Coronary Artery Bypass Grafting With Ascending Aortic Replacement
This retrospective study investigates early outcomes after CABG as well as graft patency rate in patients with concomitant AAR. 35 patients undergoing CABG with concomitant AAR (CABG+AAR group) were case-control matched to 35…
- Trial name
- NCT07071857
- Testing
- ECG CT angiography, TTFM, computed tomography of the aorta and/or grafts
- Volunteers
- 70 people
- Sponsor
- Tomsk Cardiology Research Institute
Coronary Arteries
Ten-Year Outcomes of Stents Versus Coronary-Artery Bypass Grafting for Left Main Coronary Artery Disease
The purpose of this study is to evaluate long-term outcome of treatment(percutaneous coronary intervention or coronary-artery bypass graft) in unprotected left main coronary artery stenosis in Korea.
- Trial name
- MAIN COMPARE (NCT02791412)
- Testing
- percutaneous coronary intervention or coronary-artery bypass graft
- Where
- 12 sites in South Korea
- Volunteers
- 2,240 people
- Sponsor
- Seung-Jung Park
Myocardial Infarction, Acute, ST Segment Elevation Myocardial Infarction
A Trial on the Role of Community Pharmacist in Improving Adherence and Clinical Outcomes in Post-Infarction
The purpose of this pilot study is to evaluate the effectiveness of the active involvement of Community Pharmacists in improving adherence to medical prescriptions in patients with acute myocardial infarction (AMI), reducing the…
- Conditions
- Myocardial Infarction, Acute, ST Segment Elevation Myocardial Infarction, Non-ST Elevation Myocardial Infarction (nSTEMI)
- Trial name
- IM-ADHERENCE (NCT03621111)
- Testing
- Patient-counseling, Patient self-administered questionnaire, Pills counts
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda ULSS 5 Polesana
Angina Pectoris
Comparison of Loading Strategies With Antiplatelet Drugs in Patients Undergoing Elective Coronary Intervention
Use of high loading doses of clopidogrel (antiplatelet drug) just before coronary interventions is associated with improved outcomes after coronary stenting.
- Trial name
- SASSICAIA (NCT02548611)
- Testing
- Prasugrel, Clopidogrel
- Where
- 5 sites in Germany, Hungary
- Volunteers
- 795 people
- Sponsor
- LMU Klinikum
Coronary Artery Disease
Programme to Optimise Risk Factors in Patients Waiting for Coronary Artery Bypass Surgery
The time spent waiting for heart surgery can be extremely stressful. This programme aims to address this by providing a home-based, nurse-led support and education programme.
- Trial name
- NCT00124371
- Testing
- a nurse led home-based education and support programme
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Coronary Heart Disease
Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - SAfety & EffectiveneSS of Drug-ElUting Stents & Anti-platelet REgimen
Objectives 1. To compare the safety and long-term effectiveness of coronary stenting with the new platform Everolimus-Eluting coronary stenting system (EECSS, Promus Element) compared with the Zotarolimus-Eluting coronary…
- Trial name
- HOST-ASSURE (NCT01267734)
- Testing
- Everolimus-eluting coronary stenting system (EECSS, Promus Element), Zotarolimus-eluting coronary stenting system (ZECSS, Endeavor Resolute), Triple anti-platelet therapy (TAT)
- Where
- South Korea
- Volunteers
- 3,750 people
- Sponsor
- Seoul National University Hospital
Troponin, Age
NIHR CV Health Informatics Collaborative
The National Institute for Health Research (NIHR) Cardiovascular Health Informatics Collaborative is an observational, multi-centre and longitudinal study of clinical data from collaborating hospitals.
- Conditions
- Troponin, Age, Mortality, Acute Coronary Syndrome
- Trial name
- NHIC-CV (NCT03507309)
- Volunteers
- 257,948 people
- Sponsor
- Imperial College London
Coronary Artery Disease
Balloon-Stent Kissing Technique Versus Jailed Wire Technique for the Coronary Bifurcation Lesions
To compare the immediate and long-term clinical outcomes between Balloon-Stent Kissing Technique (BSKT) and Jailed Wire Technique (JWT) for the interventional treatment of coronary bifurcation lesions.
- Trial name
- NCT03429634
- Testing
- Balloon-Stent Kissing technique, Jailed Wire technique
- Where
- China
- Volunteers
- 89 people
- Sponsor
- Dalian University
ECMO Treatment, ARDS (Acute Respiratory Distress Syndrome)
Ciprofol's Impact on Oxygenator Function in Extracorporeal Membrane Oxygenation (ECMO) Patients
This study evaluates the safety and effectiveness of Ciprofol, a new sedative, in critically ill patients receiving Extracorporeal Membrane Oxygenation (ECMO), a life-support system for heart or lung failure.
- Conditions
- ECMO Treatment, ARDS (Acute Respiratory Distress Syndrome), ECMO and Acute MI, Respiratory Failure Patients Treated With ECMO
- Trial name
- CIP-OXY (NCT06934811)
- Testing
- Ciprofol, Midazolam
- Volunteers
- 30 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Coronary Artery Disease
Effect of Colchicine on Progression of Known Coronary Atherosclerosis in Patients With Stable Coronary Artery Disease
This is a randomized double-blind, placebo-controlled, investigator-initiated trial that compares Colchicine 0.5mg/day with placebo, among patients with stable CAD.
- Trial name
- EKSTROM (NCT06342609)
- Testing
- Colchicine 0.5 MG
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Coronary Artery Disease
ENdothelial Healing Assessment With Novel Coronary tEchnology
This is a prospective, non-randomized, single center clinical trial to assess neointimal coverage on the stent or scaffold strut and apposition of SYNERGY™ and ABSORB in minimum of 12 eligible human subject at 4 month and 12…
- Trial name
- ENHANCE (NCT02747199)
- Testing
- SYNERGY stent, BVS ABSORB scaffold
- Volunteers
- 13 people
- Sponsor
- University of Malaya
Myocardial Ischemia
A Comparison of the Effects of Intraoperative Administration of Metoprolol or Esmolol on General Anesthetic Requirement
We will compare three study groups receiving metoprolol, esmolol, or placebo. Level of anesthesia will be titrated to achieve the same range of BIS value in all groups.
- Trial name
- NCT00756236
- Testing
- Metoprolol, Esmolol, P-Group
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Oklahoma
Coronary Disease
Study on Registration of Xinyuan Capsule
The purpose of this study is get to know what and how Xinyuan capsule in hospital results in drug-induced liver injury or adverse drug reactions from a cohort event monitoring as registration research.
- Trial name
- NCT03197844
- Volunteers
- 3,000 people
- Sponsor
- China Academy of Chinese Medical Sciences
Atherosclerosis, Cardiovascular Diseases
Coffee Consumption and Coronary Artery Calcium Score
Coffee is one of the dietary factors associated with cardiovascular disease (CVD) but its role in the cardiovascular system is not yet clear.
- Trial name
- NCT03139071
- Where
- Brazil
- Volunteers
- 4,426 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Coronary Artery Disease
Comparison of One-stop Hybrid Revascularization Versus Percutaneous Coronary Intervention for the Treatment of Multi-vessel Disease
The "one-stop" hybrid coronary revascularization combines minimally invasive direct coronary artery bypass (MIDCAB) and PCI to be performed in the hybrid operating suite, an enhanced operating room equipped with radiographic…
- Trial name
- NCT01035034
- Testing
- Hybrid MIDCAB/PCI, PCI with DES
- Where
- 2 sites in China
- Volunteers
- 480 people
- Sponsor
- China National Center for Cardiovascular Diseases
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