Clinical trials: Coronary Artery Bypass
Coronary Artery Bypass
TELEsurveillance of Patients in PostopErative Bridge surgeryAge CoronairE
More than 20,000 patients benefit from coronary bypass surgery in France each year. Median discharge without complication is eight days postoperatively, whereas by day four after surgery, hospitalization is only necessary for…
- Trial name
- TELE-PEACE (NCT04236271)
- Testing
- connected objects
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Patient Depression, Anxiety, Stress and Pain
The Effect of Listening to Holy Quran Recital on Depression, Anxiety and Stress Post CABG
Coronary artery bypass graft (CABG) is one of the most common surgical treatments for coronary artery disease. CABG has many beneficial outcomes for patients.
- Trial name
- NCT05419544
- Testing
- Holy Quran Recital effect
- Where
- 2 sites in Jordan
- Volunteers
- 128 people
- Sponsor
- Applied Science Private University
Coronary Disease, Myocardial Infarction
Stem Cell Therapy to Improve Myocardial Function in Patients Undergoing Coronary Artery Bypass Grafting (CABG)
The purpose of this study is to determine whether intracoronary transfer of autologous bone marrow cells can induce angiogenesis, subsequently improving regional myocardial perfusion, and finally resulting in improved systolic…
- Trial name
- NCT00395811
- Testing
- Bone Marrow Stem Cell Therapy combined CABG
- Where
- China
- Volunteers
- 50 people
- Sponsor
- China National Center for Cardiovascular Diseases
Postoperative Pain, Coronary Artery Bypass Grafting
Serratus Anterior Plane and PECS II Blocks After Coronary Artery Bypass Grafting
This prospective randomized placebo-controlled trial was designed to evaluate the effects of ultrasound-guided bilateral pectoralis (PECS II) and serratus anterior plane (SAP) blocks on postoperative recovery in adult patients…
- Trial name
- NCT06793436
- Testing
- Bilateral Serratus Anterior Plane Block, Bilateral PECS II Block
- Where
- Turkey (Türkiye)
- Volunteers
- 243 people
- Sponsor
- Yuzuncu Yil University
Hyperalgesia, Opioid Use
Hyperalgesia, Persistent Pain, and Fentanyl Dosing in On-Pump Coronary Artery Bypass Grafting
Randomized, double-blinded, three arm study in adult patients undergoing first time coronary artery bypass grafting (CABG) surgery with median sternotomy.
- Conditions
- Hyperalgesia, Opioid Use, Pain, Postoperative, Pain, Chronic
- Trial name
- NCT03450161
- Testing
- Fentanyl dosing schemes
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- University Hospital, Ghent
Coronary Artery Bypass Grafting, Antiplatelet Therapy
DACAB Trial: Follow-up Extension
This study will include the subjects who enrolled in DACAB trial (NCT02201771) to observe clinical outcomes 5 years after coronary artery bypass grafting（CABG）.
- Trial name
- DACAB-FE (NCT03987373)
- Testing
- non-interventional
- Where
- 6 sites in China
- Volunteers
- 500 people
- Sponsor
- Ruijin Hospital
Hemodilution, Coronary Artery Disease
Retrograde Autologous Priming and Mannitol for Reducing Hemodilution in Cardiac Surgery
Hemodilution reduces concentrations of blood constituents: concentration of hemoglobin, red blood cells (hematocrit), physiological ions and coagulation factors that can contribute to impaired hemostasis and increasing the risk…
- Conditions
- Hemodilution, Coronary Artery Disease, Fluid Overload
- Trial name
- RAPPER-MAN (NCT04870073)
- Testing
- Retrograde autologous priming, Mannitol, Conventional Priming
- Where
- Canada
- Sponsor
- Hamilton Health Sciences Corporation
Coronary Artery Bypass Grafting, Secondary Preventions
Quality Measurement and Improvement Study of Surgical Coronary Revascularization: Secondary Prevention
The investigators have identified underuse of secondary prevention medications at discharge of patients underwent coronary artery bypass grafting (CABG) in China.
- Trial name
- MISSION-1 (NCT02430012)
- Testing
- Quality improvement strategies
- Where
- China
- Volunteers
- 10,009 people
- Sponsor
- China National Center for Cardiovascular Diseases
Atrial Fibrillation, Ischemic Heart Disease
Epicardial Fat Pads Ablation During Coronary Surgery
The aim of this prospective randomized study was to assess the efficacy of ablation of the ganglionated plexi localized in the epicardial fat pads for preventing recurrences of atrial tachyarrhythmia in patients with paroxysmal…
- Trial name
- NCT02984371
- Testing
- Coronary artery bypass grafting, Epicardial ganglionated plexi ablation, implantable loop recorder
- Where
- 2 sites in Russia
- Volunteers
- 264 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Heart Defects, Congenital, Hypertension, Pulmonary
Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery
This clinical trial will determine the safety and effectiveness of intravenous L-citrulline in children undergoing cardiopulmonary bypass during heart surgery.
- Trial name
- NCT00335244
- Testing
- L-citrulline
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Asklepion Pharmaceuticals, LLC
Ischemic Heart Disease
Sevoflurane Effect on Left Atrial Performance: A Transoesophageal Echocardiographic Study
The left atrial performance is affected by the preload as well as the afterload. The LA active pumping is increased by stretching of the LA but within limits, after which the active pumping declines.
- Trial name
- NCT03999463
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Coronary Artery Disease, Coronary Artery Bypass Grafting
Total Arterial Revascularization (TAR)
Total arterial revascularisation with in-situ confihuration of BITA is superior than y-graft in patients underwent CABG.
- Trial name
- NCT03753048
- Testing
- Y-Graft, In-Situ
- Where
- Russia
- Volunteers
- 880 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Stroke Volume Variation
Effect of Wide Pulse Pressure on the Predictability of Stroke Volume Variation for Fluid Responsiveness in Patients Undergoing Off-pump Coronary Artery Bypass Graft
The investigators examined the predictability of stroke volume variation for fluid responsiveness in patients with wide pulse pressure undergoing off-pump coronary artery bypass graft
- Trial name
- NCT01404455
- Testing
- HES 130/0.4 (VoluvenⓇ, Fresenius Kabi, Graz, Austria) 500mL loading
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Severance Hospital
Cardiac Disease
The Effects of Neurophysiological Facilitation Techniques After Coronary Artery Bypass Graft Surgery
The aim of the study is to investigate the effects of neurophysiological facilitation techniques, applied in addition to Phase I cardiac rehabilitation in the early postoperative period after coronary artery bypass graft (CABG)…
- Trial name
- NCT06640699
- Testing
- exercise
- Volunteers
- 36 people
- Sponsor
- Istanbul University - Cerrahpasa
Endothelial Function of Saphenous Vein Grafts
Investigation of Endothelium in Saphenous Vein Grafts
This is a single center prospective study of 30 patients undergoing elective heart bypass surgery (CABG) with at least two vein grafts from the leg (SVG).
- Trial name
- NCT01510821
- Testing
- Use of Maquet Vasoshield Pressure-limiting syringe on SVG, Use of non-regulated syringe on SVG
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Emory University
Coronary Artery Disease, Myocardial Ischemia
The eSVS® Mesh Randomized Post-Market Study
The purpose of this study is to evaluate patency rates of the external Saphenous Vein Support (eSVS) Mesh Saphenous Vein Grafts (SVG) and Control SVG at 3-6 months and 24 months.
- Conditions
- Coronary Artery Disease, Myocardial Ischemia, Coronary Disease, Heart Diseases
- Trial name
- NCT01462721
- Testing
- eSVS® Mesh
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- Kips Bay Medical, Inc.
Complications Due to Coronary Artery Bypass Graft, Graft Failure
Patency-Coronary Trial
Heart bypass surgery is used to increase blood flow to the heart. This surgery is usually done using a heart-lung machine (on-pump surgery) allowing the surgeon to perform the procedure on a still heart.
- Trial name
- PATENCY (NCT01414049)
- Testing
- On-pump CABG, Off-pump CABG
- Where
- 3 sites in Canada
- Volunteers
- 1,200 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Cardiovascular Diseases
Effects of the Low-level Laser Therapy on Inflammatory Profile of the Patients With Coronary Artery Bypass Surgery
Cardiovascular diseases are the leading causes of morbidity and mortality in Brazil and surgical procedures to treat these disorders have grown dramatically in recent years.
- Trial name
- NCT02709499
- Testing
- 0J LLLT, 6J LLLT
- Volunteers
- 38 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Coronary Artery Bypass Grafting (CABG), Chronic Heart Failure
A Phase I/II Clinical Trial of Intramyocardial Injection of HucMSCs for the Treatment of Chronic Heart Failure
B2278 is a human umbilical cord mesenchymal stem cell (HucMSCs) injection derived from the umbilical cord. It has the advantages of stronger immune regulation, stronger expansion capacity, lower immunogenicity, and greater…
- Conditions
- Coronary Artery Bypass Grafting (CABG), Chronic Heart Failure, Chronic Ischemic Cardiomyopathy
- Trial name
- NCT07265349
- Testing
- Mesenchymal stem cells(HucMSCs), CABG
- Where
- 4 sites in China
- Volunteers
- 51 people
- Sponsor
- Tasly Pharmaceutical Group Co., Ltd
Coronary Artery Disease
Clinical Trial of Kryptonite for Prevention of Sternal Complications in High Risk Patients Undergoing Cardiac Surgery
Kryptonite is a non-toxic biologic polymer, that has previously been used in orthopedic surgery. The objective of our study is to demonstrate the benefits of Kryptonite in cardiac surgery patients at high risk for sternal wound…
- Trial name
- Kryptonite (NCT01368991)
- Testing
- Kryptonite, Conventional closure
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Cardiology Research UBC
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