Clinical trials: Coronary Artery Bypass
Anticoagulation, Coronary Endarterectomy
Antithrombotic Therapy After Coronary Artery Bypass Grafting Combined With Coronary Endarterectomy
Coronary endarterectomy (CE) combined with coronary artery bypass grafting (CABG) can be the final option for achieving complete revascularization in diffuse coronary artery disease patients.
- Trial name
- NCT05782270
- Testing
- Warfarin, DAPT, CE+CABG
- Where
- China
- Volunteers
- 202 people
- Sponsor
- China National Center for Cardiovascular Diseases
Pulse Wave Analysis
Cardiac Output Monitoring With Estimated Continuous Cardiac Output (esCCO) vs. Transpulmonary Thermodilution (TPTD)
The main goal of our study is to assess the accuracy and reproducibility of continuous beat-to-beat cardiac output (CO) measurement using pulse wave transit time in patients undergoing off-pump coronary artery bypass grafting.
- Trial name
- NCT02352324
- Testing
- Fluid responsiveness tests
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- Northern State Medical University
Coronary Artery Bypass Grafting
Comparative Study of Two Brands of Heparin Already on the Market
Two heparin brands have been in the market in Canada for several years. Heparin Leo from Leo Pharma and Hepalean from Organon. The former is standardized by B.P (British pharmacopeia) while the latter is standardized by U.S.P…
- Trial name
- NCT00848796
- Testing
- Heparin Leo and Hepalean
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Southlake Health
Coronary Artery Bypass Grafting, Myocardial Infarction
ARomatherapy for Cognitive Trajectory in Chinese After Coronary Artery Bypass Grafting
The ARCTIC-CABG (Aromatherapy for Cognitive Trajectory in Chinese after Coronary Artery Bypass Grafting) trial is a randomized, double-blind, 2-arm, parallel group, placebo-controlled study to evaluated the effects of…
- Trial name
- ARCTIC-CABG (NCT04102696)
- Testing
- Aromatherapy
- Volunteers
- 460 people
- Sponsor
- Beijing Anzhen Hospital
Anxiety, Discharge Readiness
The Effect of Nurse-led Video-assisted Discharge Training on Anxiety and Readiness for Discharge After Coronary Artery Bypass Graft Surgery
This clinical trial aims to evaluate the effect of nurse-led video-assisted discharge education on discharge readiness and anxiety in patients undergoing coronary artery bypass graft surgery.
- Conditions
- Anxiety, Discharge Readiness, Nursing, Training
- Trial name
- NCT06806631
- Testing
- Video assisted discharge training
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people
- Sponsor
- Uskudar University
Ischaemic Heart Disease, Prehabilitation
CABGpreHAB - a Feasibility Study Protocol
Patients with ischemic heart disease (IHD) awaiting coronary artery bypass graft (CABG) surgery often face challenges like advanced age, frailty, comorbidities, and physical inactivity.
- Conditions
- Ischaemic Heart Disease, Prehabilitation, Coronary Artery Bypass, Feasibility Studies
- Trial name
- NCT07035171
- Testing
- Multimodal prehabilitation intervention, Control (Standard treatment)
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Coronary Artery Disease, Coronary Artery Bypass Grafting
Preoperative Aspirin and Postoperative Antiplatelets in Coronary Artery Bypass Grafting: The PAPA CABG Study
Main Research Question(s): What is the effect of continuing aspirin until the time of coronary artery bypass graft surgery and of adding clopidogrel to aspirin after coronary artery bypass graft surgery for preventing blockage of…
- Trial name
- PAPA CABG (NCT00330772)
- Testing
- Aspirin, Clopidogrel
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Hamilton Health Sciences Corporation
Cardiac; Arteriosclerosis, Aortic Valve Disease
The Association Between Delivered Oxygen and Cerebral Impact During the Use of Cardiopulmonary Bypass.
Investigating the connection between delivered oxygen index and cerebral impact with COx (cerebral oximetry index) och cerebral injury markers during the routine use of cardiopulmonary bypass.
- Trial name
- NCT05620875
- Testing
- Cerebral injury markers, Cerebral oximetry index
- Where
- Sweden
- Volunteers
- 106 people
- Sponsor
- Uppsala University
Coronary Artery Disease, Pain, Postoperative
Parasternal Nerve Block in Cardiac Patients
Exparel is a new local analgesic (numbing medication) that is intended to be longer acting than currently available local analgesics.
- Trial name
- NCT01826851
- Testing
- Exparel
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Peter A Knight
Thoracoabdominal Aortic Aneurysm, Cardiopulmonary Bypass
CompaRison of FEmorofemoral Bypass and Left-Heart ByPass Techniques in Open Thoracoabdominal AortIc Aneurysm Repair
The study is a multicenter, two-arm, open-label, randomized, parallel-controlled trial, which plans to enroll 236 participants diagnosed with TAAA from 4 hospitals in China.
- Conditions
- Thoracoabdominal Aortic Aneurysm, Cardiopulmonary Bypass, Open Repair
- Trial name
- REPAIR (NCT07518251)
- Testing
- Thoracoabdominal aortic aneurysm repair under fCPB, Thoracoabdominal aortic aneurysm repair under LHB
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Beijing Anzhen Hospital
Post Operative Pain
Ketamine Improves Post-Thoracotomy Analgesia
Thoracotomy for lung tumor or for minimally invasive direct coronary artery bypass (MIDCAB) surgery, may be associated with debilitating pain. Ketamine was shown to enhance opioid antinociception and prevent opioid resistance.
- Trial name
- NCT00625911
- Testing
- morphine, morphine ketamine
- Where
- Israel
- Volunteers
- 44 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Patients Waiting for Elective Coronary Artery Bypass Graft Surgery
Pre-habilitation Program for Elective Coronary Artery Bypass Graft Surgery Patients
Low levels of physical fitness increase the risk of death in patients with cardiovascular disease. Although cardiac rehabilitation programs improve the health of patients after heart surgery, most patients are not referred until…
- Trial name
- NCT01914094
- Testing
- Prehab
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- St. Boniface Hospital
Coronary Artery Disease, CABG
The 10-Year Extended Follow-up of the DACAB Trial
The goal of this observational study is to learn about the very long-term effects of different antiplatelet strategies in patients who underwent coronary artery bypass grafting (CABG) and participated in the original DACAB trial.
- Conditions
- Coronary Artery Disease, CABG, Antiplatelet Therapy of Coronary Artery Bypass
- Trial name
- DACAB-FE-10Y (NCT07480629)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ruijin Hospital
Coronary Artery Disease, CABG
Clinimetric Properties of Performance Based Functional Outcome Measure After (CABG) Surgery
The purpose of this research is to determine which performance based functional outcome test among Time up and go test, Five times sit to stand test, 2 minute walk test and 6 minute walk test has the greatest significance in…
- Trial name
- NCT07060937
- Testing
- Physiotherapy Protocol
- Where
- 2 sites in Pakistan
- Volunteers
- 100 people
- Sponsor
- Riphah International University
Coronary Artery Disease, Cardiac Valve Insufficiency
Study on the Clinical Performance of Steelex® Sternum Set for Sternal Closure
The study is designed as a retrospective, international, multi-center cohort study to evaluate Steelex® Sternum Set for sternum closure.
- Conditions
- Coronary Artery Disease, Cardiac Valve Insufficiency, Aortic Valve Stenosis
- Trial name
- STERCCAS (NCT05439395)
- Testing
- Sternum Closure after Cardiac Surgery
- Where
- 2 sites in Germany, Spain
- Volunteers
- 229 people
- Sponsor
- Aesculap AG
Complication of Coronary Artery Bypass Graft
The Fusion Versus The Affinity Oxygenation Systems
This study compares between the clinical, hematological, inflammatory and neurological outcome of patients undergoing Coronary Artery Bypass Grafting (CABG) surgery in which different oxygenation systems will be used.
- Trial name
- NCT02554305
- Testing
- fusion oxygenation system, Affinity oxygenation system
- Volunteers
- 60 people
- Sponsor
- Hadassah Medical Organization
Coronary Heart Disease
Effect of Remote Ischaemic Preconditioning on Clinical Outcomes in CABG Surgery
Coronary heart disease (CHD) is the leading cause of death in the UK, accounting for 124,000 deaths (2006) and costing the UK economy over £7.9 billion a year.
- Trial name
- ERICCA (NCT01247545)
- Testing
- Remote ischaemic preconditioning, Control
- Where
- 28 sites in United Kingdom
- Volunteers
- 1,612 people
- Sponsor
- University College, London
Coronary Artery Disease
The Effect Of Antiplatelets Therapy On Saphenous Vein Coronary Artery Bypass Graft Patency
This protocol is designed to evaluate the effect of antiplatelets (Tirafiban and Prasugrel) on the incidence of early and intermediate graft patency after CABG.
- Trial name
- NCT01598337
- Testing
- Aspirin, Tirofiban, Clopidogrel
- Where
- Saudi Arabia
- Volunteers
- 200 people
- Sponsor
- Prince Sultan Cardiac Center, Adult Cardiology Department.
Post-operative Pain Management
Are Superficial Parasternal Intercostal Plane (SPIP) Blocks With Bupivacaine and With or Without Adjuvants Helpful for Post-operative Pain After Coronary Artery Bypass Grafting?
The purpose of this study is to determine whether the addition of the superficial parasternal intercostal plane (SPIP) block alone (30cc of 0.25% bupivacaine) or plus Magnesium (200mg of magnesium sulfate) or plus Magnesium +…
- Trial name
- NCT05003765
- Testing
- Bupivacaine 0.25% Injectable Solution, Bupivacaine 0.25% Injectable Solution, Magnesium Sulfate 200 mg, Bupivacaine 0.25% Injectable Solution, Magnesium Sulfate 200 mg, Buprenorphine 300 mcg
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Wayne State University
Coronary Artery Disease
CT-angiographic Follow up of Patients That Underwent Coronary Bypass Surgery Between 1993-1997
Coronary artery surgery (CABG) is necessary to improve blood circulation in many patients with coronary artery disease. This is done by using alternative blood vessels (grafts) to bypass the stenosed coronary arteries.
- Trial name
- NCT01686100
- Testing
- No touch technique, Conventional technique
- Where
- Sweden
- Volunteers
- 52 people
- Sponsor
- Örebro County Council
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