Clinical trials: Coronary Artery Bypass
Coronary Artery Bypass Grafting Surgery
ESOS (Endoscopic Saphenous Harvesting With an Open CO2 System) Trial
The ESOS (Endoscopic Saphenous harvesting with an Open CO2 System) trial is a prospective randomized trial for coronary artery bypass grafting (CABG) surgery to compare endoscopic open CO2 harvesting system versus conventional…
- Trial name
- ESOS (NCT01121341)
- Testing
- Vein harvesting
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Azienda Ospedaliera San Giovanni Battista
Ischemic Heart Disease (IHD), Off-pump Coronary Artery Bypass
Efficacy of Multiple Nerve Blocks on the Recovery of Patients Undergoing Off Pump CABG Surgeries
In cardiac surgery patients , effective pain control is crucial to support early extubation, mobilization, and cognitive recovery, yet systemic opioids carry substantial risks such as respiratory depression, delirium, and delayed…
- Conditions
- Ischemic Heart Disease (IHD), Off-pump Coronary Artery Bypass, Regional Block for Pain Control
- Trial name
- NCT07794527
- Testing
- regional nerve block with local anesthesia
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Central Sleep Apneas Syndrome, Heart Failure
PAC-IC-SAS Pilot Study - Central Sleep Apneas Syndrome and Ventricular Function
The aim of this clinical trial is to evaluate the effect of an early treatment of sleep-disordered breathing by adaptive servo-ventilation in heart failure patient following coronary artery bypass graft surgery or other coronary…
- Conditions
- Central Sleep Apneas Syndrome, Heart Failure, Coronary Artery Bypass Graft Surgery or Other Coronary Reperfusion
- Trial name
- NCT01741337
- Testing
- Adaptive servo-ventilation post-operative treatment for 6 months
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Grenoble
Thrombocytopathy
Platelet Function in Minimal Extracorporeal Circulation in CABG
Rationale: Cardiac surgery with extracorporeal circulation (ECC) triggers platelets. Minimal extracorporeal circulation system (minimal-ECC) has several advantages compared with conventional ECC amongst less platelet activation.
- Trial name
- ECCTEG (NCT01935245)
- Testing
- Mini extracorporeal circulation, Conventional extracorporeal circulation
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Coronary Artery Disease
Effectiveness of Early Cardiac Rehabilitation
The goal of this experimental study is to compare the effects of early (2nd week) cardiac rehabilitation applied in addition to usual care on functional capacity, quality of life, frailty and body composition in patients…
- Trial name
- NCT06116773
- Testing
- Training, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
Coronary Artery Bypass Grafting, Medication Adherence
Quality Measurement and Improvement Study of Surgical Coronary Revascularization: Medication Adherence
The study is a randomized controlled trial, having a plan to recruit 1000 patients underwent coronary artery bypass grafting in 1 of 5 participating sites in 2015, and randomized to either the intervention group or control group…
- Conditions
- Coronary Artery Bypass Grafting, Medication Adherence, Mobile Applications
- Trial name
- MISSION-2 (NCT02432469)
- Testing
- APP intervention
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- China National Center for Cardiovascular Diseases
Other Surgical Procedures
Objective Assessment of Technical Skills in Cardiothoracic Surgery
The goal of this research study is to develop a method of rating videos of CAB procedures that will produce a reliable assessment of a cardiothoracic surgical trainee's technical proficiency.
- Trial name
- NCT01433029
- Testing
- Surgical Video Assessments, Video Recording of CAB
- Where
- 6 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Coronary Artery Disease (CAD)
Hybrid Revascularisation by Combined Coronary Artery Bypass Graft (CABG) and PCI in Multivessel Coronary Disease
The present study is designed as a prospective, single centre, open label, observational trial. The study will collect information about the medical care patients receive during their planned procedure(s).
- Trial name
- HYBRID (NCT01443754)
- Testing
- LIMA-LAD surgical revascularization, PCI
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Ettore Sansavini Health Science Foundation
Coronary Artery Disease
Multicentre Radial Artery Patency Study: Results of Patency Beyond 5 Years After Coronary Artery Bypass Surgery
Bypass surgery is often required to treat severe coronary heart disease. Either arteries or veins can be used as bypass grafts. We wish to compare the long-term durability of the saphenous vein from the leg to that of the radial…
- Trial name
- RAPS - 5 years (NCT00187356)
- Testing
- Radial Artery and Saphenous Vein Grafts Randomized to either right coronary or left circumflex coronary artery territories
- Where
- 13 sites in Canada, New Zealand
- Volunteers
- 269 people
- Sponsor
- Sunnybrook Health Sciences Centre
Postoperative Pain
REGIONAL ANALGESIA TECHNIQUES FOR EFFECTIVE RECOVERY TO CORONARY ARTERY BYPASS SURGERIES: A RETROSPECTİVE STUDY IN A SINGLE CENTER EXPERIENCE
Background Pain after cardiac surgery is both multifocal and multifactorial. Sternotomy, sternal retraction, internal mammary dissection, posterior rib dislocation or fracture, possible brachial plexus injury, and mediastinal and…
- Trial name
- NCT05282303
- Testing
- CABG operation
- Where
- Turkey (Türkiye)
- Volunteers
- 221 people
- Sponsor
- V.K.V. American Hospital, Istanbul
Kidney Failure, Acute, Oxidative Stress Induction
N-acetylcysteine to Prevent Renal Failure
The purpose of this study is to determine the possible effect nephroprotective of N-acetylcysteine in patients with chronic kidney disease undergoing elective coronary artery bypass grafting by serial evaluation of renal function…
- Trial name
- NCT01359722
- Testing
- N-acetylcysteine, Control
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Instituto do Coracao
Coronary Disease, Cardiovascular Diseases
Prospective Russian Evaluation of Lp(a) Role in cardiovascUlar DiseasE
The purpose of this study is to explore the role of lipoprotein(a) and apolipoprotein(a) phenotype in fatal and non-fatal cardiovascular disease (CVD) events risk in coronary disease patients divided on the basis of management…
- Trial name
- PRELUDE (NCT02515747)
- Testing
- percutaneous coronary intervention, coronary artery bypass grafting
- Volunteers
- 1,400 people
- Sponsor
- Russian Cardiology Research and Production Center
Coronary Arterial Disease (CAD), Bypass Graft Occlusion
Cardiac Computed Tomography Based 3-D Printing for Optimized Coronary Artery Bypass Graft Surgery
Coronary artery bypass graft surgery (CABG) is a preferred surgical treatment in patients with widespread coronary artery disease.
- Trial name
- 3DCABG (NCT07039838)
- Testing
- 3D print of coronary arteries
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Jesper James Linde
Coronary Artery Disease
Long-term Comparison of Stenting Versus Off-pump Coronary Bypass Surgery
The randomized comparison of two strategies in coronary revascularization: bypass surgery without the use of a heart lung machine and coronary stenting procedure.
- Trial name
- OCTOSTENT (NCT00975858)
- Testing
- Coronary Revascularization
- Where
- Netherlands
- Volunteers
- 280 people
- Sponsor
- UMC Utrecht
Coronary Artery Bypass Graft With or Without ECC
Study Of Factors Favoring The Onset Of Novo Atrial Fibrillation In The Immediate Aftermath Of Coronary Artery Bypass Surgery
Before la surgery: Transthoracic cardiac echography will be done systematically, to measure among other things the size of the left atrium.
- Trial name
- NCT02042547
- Testing
- Tissue samples from the right atrium, Blood samples
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Disease Management, Diabetes Complications
Determining Rates of Cardiovascular Complications Among Patients of a Managed Diabetes Care Program
The primary objective of this study is to identify whether cardiovascular complication rates are lower in patients who participate in managed diabetes care, in comparison to provincial and national rates.
- Conditions
- Disease Management, Diabetes Complications, Diabetic Vascular Complications, Diabetic Neuropathy
- Trial name
- DECIDE (NCT00498147)
- Testing
- ADEC Program
- Where
- Canada
- Volunteers
- 1,213 people
- Sponsor
- Group Health Centre
Coronary Artery Disease, Postoperative Pain
Pectointercostal Fascial Plane Block (PIFB) Alone Versus PIFB With Rectus Sheath Block (RSB) in Cardiac Surgery
The purpose of this study is to determine if ultrasound-guided bilateral pectointercostal fascial plane blocks with bilateral rectus sheath blocks block decrease pain scores, decrease opioid consumption, improve respiratory…
- Conditions
- Coronary Artery Disease, Postoperative Pain, Respiratory Failure
- Trial name
- NCT04908449
- Testing
- Rectus sheath block with bupivacaine
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Medical College of Wisconsin
Postoperative Cognitive Dysfunction
Correlation Between Markers of Neuronal Injury and Cognitive Dysfunction After Coronary Artery Bypass Surgery
This study aims to evaluate the possible Correlation Between Serum Levels of Markers of Neuronal Injury and Cognitive Dysfunction after Coronary Artery Bypass Surgery.
- Trial name
- NCT01550159
- Where
- Brazil
- Volunteers
- 88 people
- Sponsor
- Maria José Carvalho Carmona
Coronary Artery Disease, Cardiac Autonomic Neuropathy
IMPACT OF CARDIAC AUTONOMIC NEUROPATHY ON QT AND QTC INTERVAL
This prospective observational cohort study evaluated the effect of cardiac autonomic neuropathy (CAN) on perioperative ventricular repolarization, specifically QT and corrected QT (QTc) intervals, in patients undergoing elective…
- Conditions
- Coronary Artery Disease, Cardiac Autonomic Neuropathy, QT Interval Prolongation
- Trial name
- QT interval (NCT07684768)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Haseki Training and Research Hospital
Complication of Extracorporeal Circulation, Complication of Coronary Artery Bypass Graft
Combined Use of a Novel Cardioplegic Formula With Myocardial Protection System (MPS)® Versus Cardioplexol ® in Isolated Coronary Artery Bypass Grafting (CABG) Using MiECC;
Combined use of a novel cardioplegic formula with MPS® (Myocardial protection system) versus Cardioplexol ® (colloid solution with Procaine, magnesium and potassium) in isolated CABG (coronary artery bypass grafting) using MiECC…
- Trial name
- MiECC (NCT03612388)
- Testing
- use of a cardioplegic formula in isolated CABG (coronary artery bypass grafting) using MiECC (Minimal extracorporeal circulation
- Where
- Switzerland
- Volunteers
- 211 people
- Sponsor
- University Hospital, Basel, Switzerland