Clinical trials: Coronary Artery Bypass
Heart Surgery
Association Between S-LAAO and Adverse Cardiovascular Events Among Patients Undergoing Coronary Artery Bypass Grafting.
This is a prospective, single-center, randomized, active controlled, clinical trail to assess the efficacy and safety of surgical closure of left atrial appendage (LAA) in patients undergoing coronary artery bypass graft.
- Trial name
- NCT04108169
- Testing
- Left atrial appendage occlusion surgery
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Beijing Institute of Heart, Lung and Blood Vessel Diseases
Coronary Artery Disease, Atherosclerosis
Radial Artery Patency and Clinical Outcomes Trial
Coronary Artery Bypass Graft (CABG)Surgery is commonly used to treat patients with coronary artery disease (atherosclerosis) for the relief of angina (chest pain) and improve heart muscle function.
- Trial name
- RAPCO (NCT00475488)
- Testing
- Coronary artery bypass grafting
- Where
- Australia
- Volunteers
- 605 people
- Sponsor
- Austin Health
Coronary Bypass Stenosis, Coronary Artery Bypass Grafting Surgery
Correlation Between Internal Jugular Vein Ultrasound and Electrical Cardiometry
Coronary artery bypass graft (CABG) surgery is one of the most frequently performed cardiac surgery procedures worldwide. CABG has been used for more than 40 years to relieve symptoms and to reduce the risk of death in patients…
- Trial name
- NCT05945303
- Testing
- Coronary Artery Bypass Grafting surgery
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Egymedicalpedia
Acute Kidney Injury
Preoperative Level of Hemoglobin A1c and Acute Kindey Injury After Coronary Artery Bypass Grafting Surgery
Background: The development of acute kidney injury (AKI) is an important indicator of clinical outcomes after cardiac surgery. Elevated preoperative hemoglobin A1c level may be associated with acute kidney injury in patients…
- Trial name
- NCT05390281
- Testing
- increase in serum creatinine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Bleeding, Bypass Complication
A Pre-market, Multi-center, International, Double-blind, Randomized, Two-arms, Controlled, Prospective Clinical Investigation Assessing the Safety and Performance of a Medical Device (ClearPlasma™) for the Treatment of Patients Undergoing Coronary Artery Bypass or Valve Replacement
Bleeding is a significant complication in cardiac surgery, with 10-15% of open cardiac surgery patients experiencing major intra- or post-operative bleeding.
- Conditions
- Bleeding, Bypass Complication, Valve Replacement
- Trial name
- NCT05542277
- Testing
- ClearPlasma
- Where
- 8 sites in Czechia, Israel and 1 more
- Volunteers
- 130 people
- Sponsor
- PlasFree Ltd.
Coronary Artery Disease, Atrial Fibrillation
TEmporary Spinal CoRd StiMulatIon to PrevenNt Atrial FibrillaTION AFter Cardiac Surgery
To compare of atrial arrhythmia incidence in patients with coronary artery disease and atrial fibrillation history, undergoing either coronary artery bypass grafting plus temporary spinal cord stimulation or coronary artery…
- Trial name
- TerminationAF (NCT03539354)
- Testing
- Temporary spinal cord stimulation, Coronary artery bypass grafting, B-blockers
- Where
- 2 sites in Russia
- Volunteers
- 60 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Coronary Artery Disease
Heparin Dose and Post Operative Bleeding in Cardiopulmonary Bypass Patients
Blood is anticoagulated using a drug named heparin during open-heart surgery to allow it to safely pass through the heart-lung machine which pumps the blood throughout the body during the surgery.
- Trial name
- NCT01574105
- Where
- 2 sites in Canada
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Complications Due to Coronary Artery Bypass Graft
Effects of High-intensity Inspiratory Muscle Training in Patients Undergoing Coronary Artery Bypass Grafting Surgery
Even with the advances in clinical therapy and percutaneous interventions, coronary artery bypass grafting (CABG) is still widely used in the treatment of patients with coronary artery disease (CAD).
- Trial name
- NCT02885077
- Testing
- High-intensity IMT + combined exercise
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Universidade Federal de Santa Maria
Acute Kidney Injury, Coronary Artery Disease
Renal Doppler Indices for Predicting Acute Kidney Injury After Isolated CABG
Acute kidney injury can occur after coronary artery bypass grafting (CABG). This prospective, single-center observational study will evaluate whether two measurements obtained from renal Doppler ultrasound-the renal augmented…
- Trial name
- NCT07821983
- Testing
- Renal Doppler Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Patient Undergoing CABG Surgery, Ischemic Heart Disease Patients
Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass
This trial aims to study the performance of CO2 gap, lactate level, and central venous oxygen saturation in predicting major postoperative complications after cardiac surgery with cardiopulmonary bypass
- Trial name
- NCT06839027
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Ain Shams University
Coronary Artery Disease
Clinical Trial of Kryptonite for Prevention of Sternal Complications in High Risk Patients Undergoing Cardiac Surgery
Kryptonite is a non-toxic biologic polymer, that has previously been used in orthopedic surgery. The objective of our study is to demonstrate the benefits of Kryptonite in cardiac surgery patients at high risk for sternal wound…
- Trial name
- Kryptonite (NCT01368991)
- Testing
- Kryptonite, Conventional closure
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Cardiology Research UBC
Coronary Bypass Graft Failure/Occlusion
Fondaparinux to Prevent Thrombotic Complications and Graft Failure in Patients Undergoing Coronary Artery Bypass Graft Surgery: The Fonda CABG Study
(i) Main Research Question(s): What is the effect of fondaparinux on coronary graft patency, heart attack, stroke, and death in patients who have undergone coronary artery bypass grafting (CABG)? To reliably answer this question…
- Trial name
- Fonda CABG (NCT00474591)
- Testing
- Fondaparinux
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Hamilton Health Sciences Corporation
Coronary Artery Atherosclerosis
Radial vs Vena No-Touch Assessment
This study examines the outcomes of coronary artery bypass grafting (CABG) in women at 1 year after surgery. A randomized controlled trial is planned, including a comparative analysis of two observed groups depending on the…
- Trial name
- RAVENTA (NCT07552948)
- Testing
- radial artery graft, no-touch vein graft
- Where
- Russia
- Volunteers
- 110 people
- Sponsor
- Tomsk Cardiology Research Institute
Coronary Artery Bypass
Comparison of Minimal Versus Conventional Extracorporeal Circulation in Coronary Surgery
The aim of this study is to assess the effect of minimal (MiECC) versus conventional (CECC) extracorporeal circulation on perfusion characteristics and remote end-organ protection (lungs, brain, kidneys, liver, stomach…
- Trial name
- NCT01603589
- Testing
- Coronary artery bypass grafting with the use of minimal invasive extracorporeal circulation, Coronary artery bypass grafting under conventional extracorporeal circulation
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- AHEPA University Hospital
Coronary Artery Disease, Coronary Artery Bypass Grafting
Ticagrelor-Based Dual Antiplatelet Therapy Duration in CABG
This randomized controlled trial aims to evaluate the impact of different durations of Ticagrelor-based dual antiplatelet therapy (DAPT) on saphenous vein graft (SVG) patency in patients undergoing coronary artery bypass grafting…
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Grafting, Saphenous Vein, Dual Antiplatelet Therapy
- Trial name
- NCT06981390
- Testing
- Ticagrelor + Aspirin for 3 Months (followed by aspirin monotherapy), Ticagrelor + Aspirin for 6 Months (followed by aspirin monotherapy), Ticagrelor + Aspirin for 12 Months (followed by aspirin monotherapy)
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Kexiang Liu, MD
Coronary Artery Disease, Aspirin
Effect of Preoperative Aspirin in Patients Undergoing Off-pump Coronary Artery Bypass Grafting
Effect of Preoperative Aspirin in patients undergoing Off-pump Coronary Artery Bypass Grafting. A double-blind, placebo-controlled, randomized trial.
- Trial name
- NCT03049085
- Testing
- Aspirin, vitamin C
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Medinet Heart Centre
Coronary Artery Occlusive Disease
Effect of Intraoperative Iloprost Inhalant on Hemodynamic Stability in Patients Undergoing Off-pump Coronary Artery Bypass Graft Surgery
Considering that the cause of hemodynamic instability during OPCAB is closely related to right ventricular dysfunction with pulmonary artery hypertension, the use of inhaled iloprost (a selective pulmonary vasodilator) in…
- Trial name
- NCT04598191
- Testing
- Iloprost, Control (Normal saline)
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Coronary Artery Bypass Grafting
Treatment of Moderate Vein Graft Lesions With Paclitaxel Drug Eluting Stents: The VELETI Trial
HYPOTHESIS 1. Sealing moderate SVG lesions with the TAXUS stent prevents SVG atherosclerosis progression as evaluated by IVUS. 2.
- Trial name
- VELETI (NCT00289835)
- Testing
- Paclitaxel eluting stent
- Where
- Canada
- Volunteers
- 57 people
- Sponsor
- Laval University
Cardiac Surgery Intensive Care Treatment
Identification of Dominate Stressors in the Intensive Care Unit (ICU)
Undergoing cardiopulmonary bypass surgery and the subsequent admission to the intensive care unit (ICU) is known to be a stressful event to the patient.
- Trial name
- NCT00645008
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Weill Medical College of Cornell University
Coronary Artery Occlusion
Neuroaxial Prophylaxis for CABG
Investigators plan to study the effect of thoracic epidural analgesia on postoperative parameters (complication rate, duration of hospitalization, mortality, etc.) of coronary artery bypass grafting.
- Trial name
- NCT04244435
- Testing
- CABG, thoracic epidural analgesia, analgesia of opioids
- Where
- Russia
- Volunteers
- 300 people
- Sponsor
- Volgograd State Medical University
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