Clinical trials: Coronary Artery Bypass
Frail Elderly Syndrome, Coronary Heart Disease
Frailty Syndrome in Daily Practice of Interventional Cardiology Ward
The impact of frailty on immediate and long term outcomes of invasive treatment of coronary artery disease is not fully characterized.
- Conditions
- Frail Elderly Syndrome, Coronary Heart Disease, Acute Coronary Syndrome, Coronary Artery Bypass Grafting
- Trial name
- FRAPICA (NCT03209414)
- Where
- Poland
- Volunteers
- 1,000 people
- Sponsor
- Medical University of Silesia
Coronary Artery Disease, Aortic Valve Disease
Clinical Evaluation of a Modular Extracorporeal Circulation Circuit
The purpose of this clinical research study is the design of a novel modular hybrid system extracorporeal circulation circuit for open heart procedures that could easily be converted from a closed to a semi-closed circuit…
- Conditions
- Coronary Artery Disease, Aortic Valve Disease, Mitral Valve Disease, Aortic Aneurysm
- Trial name
- MiECC MODULAR (NCT02000544)
- Testing
- Modular Cardiopulmonary Bypass Circuit
- Where
- Greece
- Volunteers
- 403 people
- Sponsor
- AHEPA University Hospital
Coronary Artery Disease
Tranexamic Acid in Clopidogrel Exposure to Decrease Hemorrhage and Transfusion
The use of platelet aggregation inhibitors, including aspirin and clopidogrel(CPDG), has become a standard management strategy for patients with acute coronary syndrome.
- Trial name
- TRACED (NCT01060163)
- Testing
- Tranexamic Acid, Saline
- Where
- 7 sites in China
- Volunteers
- 552 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Metabolism Disorder
Conventional Fasting Versus Lipid/Carbohydrate Infusion for Coronary Bypass Patients
Comparative study between conventional fasting versus overnight infusion of lipid or carbohydrate on free fatty acids and insulin in obese patients undergoing elective first time on-pump coronary artery bypass grafting.
- Trial name
- NCT03033667
- Testing
- G group, group L, Group C
- Volunteers
- 63 people
- Sponsor
- Cairo University
Coronary Disease
Using Intraoperative Coronary Bypass Graft Imaging to Improve Graft Patency
The primary objective of the proposed study is to determine if a strategy of intraoperative patency assessment and graft revision can decrease the rate of graft occlusion or significant stenosis (>50%) at 6-12 weeks after…
- Trial name
- GRIIP (NCT00187421)
- Testing
- Indocyanine green intraoperative angiogram and transit-time flowmetry
- Where
- Canada
- Volunteers
- 156 people
- Sponsor
- Sunnybrook Health Sciences Centre
Multivessel Coronary Artery Disease
Myocardial Hybrid Revascularization Versus Coronary artERy Bypass GraftING for Complex Triple-vessel Disease
This is a pilot randomized study that aim to assess the safety and feasibility of a hybrid myocardial revascularization strategy (coronary artery by-pass graft and percutaneous intervention) in comparison with conventional…
- Trial name
- MERGING (NCT02226900)
- Testing
- Hybrid Revascularization, Conventional Coronary Artery Bypass Surgery
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- InCor Heart Institute
Cardiovascular Diseases
Effects of the Low-level Laser Therapy on Inflammatory Profile of the Patients With Coronary Artery Bypass Surgery
Cardiovascular diseases are the leading causes of morbidity and mortality in Brazil and surgical procedures to treat these disorders have grown dramatically in recent years.
- Trial name
- NCT02709499
- Testing
- 0J LLLT, 6J LLLT
- Volunteers
- 38 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Coronary Artery Disease, Peripheral Nerve Blocks
Recto-intercostal Block for Coronary Artery Bypass Grafting
This interventional study aims to learn about the postoperative analgesic efficacy of a new fascial plane block, recto-intercostal fascial plane block, at coronary artery bypass grafting with sternotomy.
- Conditions
- Coronary Artery Disease, Peripheral Nerve Blocks, Sternotomy
- Trial name
- NCT06418100
- Testing
- The recto intercostal fascial plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Haseki Training and Research Hospital
Vasodilation
Effects of Exercise Training on Vascular Endothelial Function of Patients Submitted to Coronary Artery Bypass Graft
Objective: To observe the effects of exercise training on vascular endothelial function in patients undergoing coronary artery bypass graft (CABG) alone in phase III after six months of Cardiac rehabilitation programs (CRP).
- Trial name
- NCT02265107
- Testing
- exercise training
- Where
- Brazil
- Volunteers
- 9 people
- Sponsor
- Universidade Federal do Rio Grande (FURG)
Coronary Artery Bypass, Cardiopulmonary Bypass
The Effect of Nitroglycerin Infusion Rate on Cerebral Rewarming During Hypothermic Coronary Artery Bypass Grafting
Glyceryl trinitrate is used in coronary artery bypass grafting surgery. This surgery frequently employs hypothermic cardiopulmonary bypass, where the whole body is cooled down to 28-32 °C to arrest the heart, and protect the…
- Trial name
- nitrotherm (NCT03251599)
- Testing
- Glyceryl trinitrate 0.2, Glyceryl trinitrate 0.5
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Recep Tayyip Erdogan University
Aortic Valve Replacement, Coronary Artery Bypass Grafting
Hemodynamic Assessment of Mosaic Ultra Stented Heart Valve in the Aortic Position
The special fixation methodology of the Mosaic Ultra stented procine bioprosthesis allows valves to maintain their natural leaflet structure and root geometry which prevents leaflet calcification and improves hemodynamic…
- Trial name
- NCT00477555
- Testing
- Aortic implantation of Mosaic Ultra porcine bioprosthesis
- Where
- 11 sites in Austria, Belgium and 3 more
- Volunteers
- 43 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Coronary Artery Bypass Graft Surgery(CABG), Postoperative Pain Management
VR During Chest Tube Removal After CABG
The purpose of this randomized controlled clinical trial was to investigate whether virtual reality (VR) could reduce pain and anxiety during chest tube removal in adult patients who underwent coronary artery bypass graft (CABG)…
- Trial name
- VR-CABG (NCT07891299)
- Testing
- VR Shinecon G04EA Virtual Reality Headset
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Maltepe University
Cardiac Surgery, Cardiopulmonary Bypass
HEMO-INTEGRA: Integrated Intraoperative Hemodynamic Monitoring During Cardiac Surgery With Cardiopulmonary Bypass - A Pilot Study
HEMO-INTEGRA is a software system that integrates four domains of intraoperative hemodynamic monitoring in a single dashboard during cardiac surgery with cardiopulmonary bypass (CPB): (1) ventricular-arterial coupling (VAC)…
- Conditions
- Cardiac Surgery, Cardiopulmonary Bypass, Hemodynamic Monitoring, Ventricular-Arterial Coupling
- Trial name
- HEMO-INTEGRA (NCT07683299)
- Where
- Colombia
- Volunteers
- 30 people
- Sponsor
- Hernán Darío Castro Arias
Intracranial Embolism and Thrombosis, Postoperative Complications
TCD Detection of Gas and Solid Micro-Emboli in Patients Undergoing Coronary Artery Bypass Grafting (CABG): The Influence of Proximal Anastomosis Technique
The purpose of this study is to test the hypothesis that using three different techniques to anastomose coronary grafts to the aorta: partial occlusion, single cross clamp, or using the Heartstring anastomotic device, will change…
- Trial name
- NCT00294814
- Testing
- Proximal anastomosis using Heartstring anastomotic device
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus
Coronary Artery Disease, Myocardial Ischemia
Safety and Feasibility Evaluation of Planning and Execution of Surgical Revascularization Solely Based on Coronary CTA and FFRCT in Patients With Complex Coronary Artery Disease (FASTTRACK CABG)
To assess the feasibility of coronary computed tomography angiography (CTA) and fractional flow reserve derived from CTA (FFRCT) to replace invasive coronary angiography (ICA) as a surgical guidance method for planning and…
- Conditions
- Coronary Artery Disease, Myocardial Ischemia, Coronary Disease, Heart Diseases
- Trial name
- NCT04142021
- Testing
- Coronary computed tomography angiography
- Where
- 3 sites in Belgium, Germany and 1 more
- Volunteers
- 114 people
- Sponsor
- National University of Ireland, Galway, Ireland
Coronary Artery Disease
Rise Semi Compliant Balloon Study in Patient With CAD
Single arm, prospective, multi-center, trial designed to enrol approximately 66 patients. All patients will undergo PCI using at least one RISE SC balloon as per routine clinical practice and will be followed until discharge for…
- Trial name
- NCT04796038
- Testing
- Balloon dilatation
- Where
- 3 sites in Switzerland
- Volunteers
- 67 people
- Sponsor
- Biosensors Europe SA
Postoperative Delirium, Postoperative Stroke
Postoperative Stroke and Epiaortic Ultrasound in CABG
This study aims to investigate the incidence of postoperative stroke and neurocognitive impairment in patients undergoing coronary artery bypass grafting (CABG), with or without the use of epi-aortic ultrasound (EAU).
- Trial name
- EAU and POCD (NCT07101393)
- Testing
- Intraoperative Epiaortic Ultrasound (EAU)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Ataturk University
Percutaneous Coronary Intervention, Myocardial Infarction
Exercise Prescription in Cardiac Rehabilitation
Cardiac Rehabilitation (CR) is an effective exercise-based lifestyle therapy for patients with cardiac disease. There are two common methods of exercise prescription, an effort based exercise prescription and target heart rate…
- Conditions
- Percutaneous Coronary Intervention, Myocardial Infarction, Coronary Artery Bypass Graft
- Trial name
- NCT03925493
- Testing
- Graded Exercise Stress test (GXT) with Target Heart Rate Range, Heart rate monitors
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Baystate Medical Center
Coronary Disease, Heart Diseases
Effects of Magnesium on Individuals Undergoing Coronary Artery Bypass Graft Surgery
The purpose of this study is to examine the effects of supplemental magnesium on the neurocognitive function of individuals undergoing coronary artery bypass graft (CABG) surgery.
- Conditions
- Coronary Disease, Heart Diseases, Cardiovascular Diseases, Neurologic Manifestations
- Trial name
- POINT (NCT00041392)
- Testing
- Magnesium, 0.9% saline
- Where
- United States
- Volunteers
- 389 people
- Sponsor
- Duke University
Coronary Artery Bypass, Anesthesia
Sustainable Anesthesia in Myocardial Revascularization Surgery.
Introduction: Greenhouse gases threaten the health and safety of humanity. The Declaration of Helsinki seeks to protect human health and emphasizes the urgency of implementing sustainable strategies.
- Conditions
- Coronary Artery Bypass, Anesthesia, Sustainability
- Trial name
- NCT07508865
- Testing
- Optimized recovery, Standard Anesthetic Practice
- Where
- Chile
- Volunteers
- 116 people
- Sponsor
- Universidad de La Frontera
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