Clinical trials: Coronary Artery Bypass
Myocardial Injury
Effects of Remote Ischemic PreConditioning in Off-pump Versus On-pump Coronary Artery Bypass Grafting(RIPCON)
Purpose Remote ischemic preconditioning (RIPC) with transient upper limb ischemia reduces myocardial injury in patients undergoing On-pump coronary artery bypass (CABG) surgery with cross-clamp fibrillation or blood cardioplegia…
- Trial name
- RIPCON (NCT01608984)
- Testing
- Remote ischemic preconditioning (RIPC), Coronary artery bypass grafting (CABG) without remote ischemic preconditioning protocol, Off-pump Coronary artery bypass surgery without remote ischemic preconditioning
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Complete Revascularization, Coronary Artery Bypass Grafting
Complete Revascularization Via Inferior Part-sternotomy
To verify the effectiveness and safety of minimally invasive coronary artery bypass grafting for complete revascularization of multivessel coronary artery disease via inferior part-sternotomy, We aim to randomize 260 patients…
- Conditions
- Complete Revascularization, Coronary Artery Bypass Grafting, Multivessel Coronary Artery Disease
- Trial name
- NCT05835167
- Testing
- Inferior part-sternotomy, Full median sternotomy
- Volunteers
- 260 people
- Sponsor
- China National Center for Cardiovascular Diseases
Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis
Effects of Exercise Training on Left Ventricular Function in Type 2 Diabetic Patients Post Coronary Artery Bypass Graft
The purpose of this study is to investigate the changes of cardiorespiratory fitness and left ventricular function in type 2 diabetes after uncomplicated coronary artery bypass graft (CABG) surgery.
- Conditions
- Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Post Coronary Artery Bypass Grafting
- Trial name
- NCT00172536
- Testing
- Exercise training, Control
- Where
- Taiwan
- Volunteers
- 65 people
- Sponsor
- National Taiwan University Hospital
Coronary Artery Disease
CABG Based on CT-FFR Versus Conventional Coronary Angiography
The aims of study are (1) to compare early and 1-year graft patency rates in patients who underwent coronary artery bypass grafting (CABG) based on conventional coronary angiography(CAG) versus cardiac computed…
- Trial name
- NCT06028165
- Testing
- Coronary artery bypass grafting based on conventional coronary angiography, Coronary artery bypass grafting based on cardiac computed tomography-derived fractional flow reserve.
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Myongji Hospital
Saphenous Vein Graft Disease
Ticagrelor Antiplatelet Therapy to Reduce Graft Events and Thrombosis
Saphenous vein graft disease remains an unresolved medical problem. Many vein grafts occlude in the first year after bypass surgery, leading to adverse cardiovascular outcomes, including recurrent angina, myocardial infarction…
- Trial name
- TARGET (NCT02053909)
- Testing
- Aspirin, Ticagrelor
- Where
- 2 sites in United States, Canada
- Volunteers
- 250 people
- Sponsor
- Boca Raton Regional Hospital
This Study is Being Conducted to Collect Echocardiographic Data to Test the Lumify Ultrasound With Hemodynamic Automation Device
Testing Automated Echocardiography
The purpose of this research is to determine if software can accurately predict certain heart parameters from chest wall ultrasound (non-radiation, non-invasive, imaging modality).
- Trial name
- NCT04943965
- Testing
- Ultrasound imaging
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Pennsylvania
Post-operative Pain Management
Are Superficial Parasternal Intercostal Plane (SPIP) Blocks With Bupivacaine and With or Without Transversus Abdominis Plane Block (TAP) Helpful for Post-operative Pain After Coronary Artery Bypass Grafting?
The purpose of this study is to determine whether superficial parasternal intercostal plane (SPIP) block alone or with transverses abdominis plane (TAP) block can improve post-operative pain in patients undergoing cardiothoracic…
- Trial name
- NCT05090735
- Testing
- SPIP and TAP Block, SPIP Block
- Volunteers
- 100 people
- Sponsor
- Wayne State University
Coronary Artery Disease
The Effect of Video Education on Pain, Anxiety and Knowledge Levels of Coronary Bypass Graft Surgery Patients
The aim of this research to examine the effectiveness of video-education on pain, anxiety, and knowledge levels on adult patients undergoing coronary artery bypass graft surgery.
- Trial name
- NCT06174090
- Testing
- Coronary bypass graft surgery video education
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Baskent University
Coronary Artery Disease
Perioperative Depression and Postoperative Arrhythmia in Elective Coronary Bypass Graft Surgery
Postoperative arrhythmias (heart irregularities) are one of the most common complications after cardiac surgery and are associated with increased morbidity and mortality.
- Trial name
- NCT00622024
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University Health Network, Toronto
OPCABG
Study on the Myocardial Protective Effect of Upper Limb Ischemic Preconditioning in Patients Undergoing Off-pump Coronary Artery Bypass Grafting
The purpose of the study was to verify the myocardial protective effect of RIPC in patients undergoing OPCABG.
- Trial name
- NCT03340181
- Testing
- RIPC
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Shanghai Zhongshan Hospital
Coronary Artery Disease, Coronary Artery Bypass Graft (CABG)
The Effect of Ultra-Fast-Track Cardiac Anesthesia in Coronary Artery Bypass Grafting Surgery
This randomized controlled trial aims to evaluate the impact of Ultra-Fast-Track (UFT) anesthesia on postoperative recovery in patients undergoing elective coronary artery bypass grafting (CABG).
- Trial name
- NCT07207421
- Testing
- Ultra-Fast-Track Anesthesia, Standart care anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Adiyaman University Research Hospital
Systemic Inflammatory Response Syndrome (SIRS), Leukocyte Disorders
Effects of Cardiopulmonary Bypass (CPB)-Leukocyte Filtration on Interleukins Serum Levels and Pulmonary Function
To test the hypothesis that leukocyte filtering during cardiopulmonary bypass (CPB) might reduce the inflammatory response and protect the lungs against the acute injury
- Conditions
- Systemic Inflammatory Response Syndrome (SIRS), Leukocyte Disorders, Complications Due to Coronary Artery Bypass Graft
- Trial name
- PulmFunction (NCT01469676)
- Testing
- Filtering group LG-6, Pall Biomedical Products
- Volunteers
- 22 people
- Sponsor
- University of Sao Paulo
Myocardial Reperfusion Injury, Hypoxia
Effects of Hypoxic-hyperoxic Preconditioning in Cardio-surgical Patients
Coronary artery bypass grafting (CABG) with cardiopulmonary bypass is a common surgical therapy for patients suffering from coronary artery diseases.
- Conditions
- Myocardial Reperfusion Injury, Hypoxia, Hyperoxia, Coronary Artery Disease
- Trial name
- NCT05354648
- Testing
- Hypoxic-hyperoxic preconditioning
- Volunteers
- 120 people
- Sponsor
- Alexander Averyanov
Prehabilitation, Cardiac Surgery
Feasibility of Physical Prehabilitation for High-Risk Patients Undergoing Cardiac Surgery Via Sternotomy
Rationale Cardiac surgery via median sternotomy carries an elevated risk of postoperative complications and delayed functional recovery.
- Conditions
- Prehabilitation, Cardiac Surgery, Risk Assesment, Aortic Valve
- Trial name
- PREPA-STER (NCT07893184)
- Testing
- Physical Prehabilitation Intervention
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Maastricht University Medical Center
Ischaemic Heart Disease, Contrast-induced Nephropathy
Trial to Assess Whether Computed Tomography Cardiac Angiography Can Improve Invasive Coronary Angiography in Bypass Surgery Patients
A large number of patients with symptomatic ischaemic heart disease undergo coronary artery bypass grafting (CABG) to alleviate their symptoms and improve prognosis.
- Trial name
- BYPASS-CTCA (NCT07022626)
- Testing
- CTCA
- Where
- 2 sites in United Kingdom
- Volunteers
- 688 people
- Sponsor
- Barts & The London NHS Trust
Postoperative Atelectasis
GO2 PEEP Study: Bidirectional Oxygenation Valve in Postoperative Atelectasis
This study compares a novel breathing device, called the GO2 Mouthpiece, to the standard breathing tool called the incentive spirometer, thus improving respiratory dynamics of the postoperative patient.
- Trial name
- NCT04253834
- Testing
- Incentive spirometer, GO2 Mouthpiece
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Multi Vessel Coronary Artery Disease
Xeltis Coronary Artery Bypass Graft (XABG) First in Human (FIH)
A prospective, single arm, non-randomized FIH feasibility study to evaluate the preliminary safety and performance of the XABG technology in patients with multi-vessel atherosclerotic coronary artery disease, scheduled by the…
- Trial name
- XABG FIH (NCT04545112)
- Testing
- CABG
- Where
- 4 sites in Belgium, Lithuania and 1 more
- Volunteers
- 20 people
- Sponsor
- Xeltis
Postoperative Acute Kidney Injury After Off-pump Coronary Artery Bypass Graft
Effect of N-acetylcysteine on Prevention of Acute Kidney Injury in High Risk Patients Undergoing Off-pump Coronary Artery Bypass Graft
N-acetylcysteine may prevent acute kidney injury in high risk patients undergoing off-pump coronary artery bypass graft.
- Trial name
- NCT01394419
- Testing
- N-acetylcysteine, Saline
- Where
- South Korea
- Volunteers
- 115 people
- Sponsor
- Yonsei University
Coronary Artery Bypass Graft (CABG)
Saudi CABG Audit and Registry
The Saudi CABG Audit and Registry (SCAR) is a prospective, multicenter national clinical quality registry designed to systematically collect perioperative and long-term outcome data for all patients undergoing coronary artery…
- Trial name
- SCAR (NCT07316777)
- Testing
- Prospective Clinical Data Collection
- Volunteers
- 3,000 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Brain Ischemia, Postoperative Confusion
Impact of Remote Ischemic Preconditioning Preceding Coronary Artery Bypass Grafting on Inducing nEuroprotection
Coronary artery disease (CAD) is the leading cause of death worldwide. Patients with severe CAD are often treated with coronary artery bypass grafting (CABG).
- Trial name
- RIPCAGE (NCT02177981)
- Testing
- Remote ischemic preconditioning, Control
- Where
- Croatia
- Volunteers
- 70 people
- Sponsor
- University of Zagreb
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