Clinical trials: Coronary Artery Bypass
Type 2 Diabetes Mellitus, Cardiovascular Disease
Mechanistic Assessment of the Properties of Saxagliptin in Subjects Undergoing Coronary Artery Bypass Graft Surgery
Individuals with type 2 diabetes mellitus (T2DM) are at increased risk for cardiovascular events (for example, heart attack) and the risk is related to one's overall control of blood glucose levels.
- Trial name
- MAPSS (NCT01765270)
- Testing
- Saxagliptin
- Where
- 10 sites in United States
- Volunteers
- 12 people
- Sponsor
- Duke University
Primary Valvular Heart Disease With Comorbid Coronary Artery Disease, Planned to Undergo Elective On-pump Valve Surgery Due to Primary Mitral and/or Aortic Valvular Heart Disease
Quantitative Flow Ratio (QFR) Guided Coronary Artery Bypass Grafting for Patients Undergoing Primary Valve Surgery With Concomitant Coronary Artery Disease
This is a multicenter, prospective, randomized, blinded, controlled clinical study in patients with planned primary valvular surgery and comorbid coronary artery lesions with diameter stenosis of ≥ 50%, to compare the…
- Trial name
- FAVOR IV-QVAS (NCT03977129)
- Testing
- QFR-guided strategy, CAG-guided strategy
- Where
- 12 sites in China
- Volunteers
- 792 people
- Sponsor
- Ruijin Hospital
Coronary Heart Disease, Cardiovascular Diseases
Comparison Between Propofol and Inhalational Anaesthetic Agents on Cardiovascular Outcomes Following Cardiac Surgery
The objective of this research proposal is to find out whether comparing the two different anaesthetic maintenance techniques (Propofol vs volatile anaesthetics) in adult patients undergoing heart surgery is practical for the…
- Trial name
- COPIA (NCT04039854)
- Testing
- Isoflurane, Sevoflurane or Desflurane, Propofol
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- King's College Hospital NHS Trust
Heart Surgical Procedure
Blood Velocity Variation in Right Renal and Superior Mesenteric Arteries During Cardio-pulmonary Bypass
The cardiopulmonary by-pass technique, used in cardiac surgery to obtain a bloodless operating field and an immobile heart, determines important effects on the blood vessel wall, especially when a continuous and non-continuous…
- Trial name
- NCT06009809
- Testing
- transesophageal echocardiogram
- Where
- Italy
- Volunteers
- 92 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
CAD, LIMA
Long LIMA Patch on Left Anterior Descending Coronary Artery in CABG
To assess the effect of LIMA patch as a method for the reconstruction on diffusely diseased LAD in the early and midterm outcomes
- Conditions
- CAD, LIMA, CABG
- Trial name
- NCT06173609
- Testing
- CABG
- Volunteers
- 50 people
- Sponsor
- Assiut University
Coronary Artery Bypass, Anesthesia
Sustainable Anesthesia in Myocardial Revascularization Surgery.
Introduction: Greenhouse gases threaten the health and safety of humanity. The Declaration of Helsinki seeks to protect human health and emphasizes the urgency of implementing sustainable strategies.
- Conditions
- Coronary Artery Bypass, Anesthesia, Sustainability
- Trial name
- NCT07508865
- Testing
- Optimized recovery, Standard Anesthetic Practice
- Where
- Chile
- Volunteers
- 116 people
- Sponsor
- Universidad de La Frontera
Coronary Syndrome
Medical Evaluation of Scanner in Coronary Syndrome
Many recent publications have reported encouraging results on diagnostic cardiac multislice CT performance in 1) coronary artery disease, 2) coronary arterial bypass graft potency and 3) intrastent restenosis.
- Trial name
- EVASCAN (NCT00709709)
- Testing
- multislice coronary scan
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Frail Elderly Syndrome, Coronary Heart Disease
Frailty Syndrome in Daily Practice of Interventional Cardiology Ward
The impact of frailty on immediate and long term outcomes of invasive treatment of coronary artery disease is not fully characterized.
- Conditions
- Frail Elderly Syndrome, Coronary Heart Disease, Acute Coronary Syndrome, Coronary Artery Bypass Grafting
- Trial name
- FRAPICA (NCT03209414)
- Where
- Poland
- Volunteers
- 1,000 people
- Sponsor
- Medical University of Silesia
Coronary Artery Disease, Heart Valve Disease
A Randomized Multicenter Clinical Study On the High Vacuum Body Cavity Drainage System Following Open Heart Surgery
The purpose of this study is to compare a new high vacuum pressure chest drainage system (NO-NUMO™) with the standard low vacuum pressure drainage system already in use in cardiac surgeries.
- Trial name
- NO-NUMO (NCT00581399)
- Testing
- NO-NUMO™ High Vacuum Body Cavity Drainage System, PVC Chest Tube
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- University of California, Irvine
Acute Coronary Syndrome
Ticagrelor Removal Study Using CytoSorb® 300 mL Device During CPB in Patients Undergoing Emergent Cardiothoracic Surgery
The aim of CyTation is to demonstrate intra-operative removal of ticagrelor by CytoSorb® hemadsorption in patients on ticagrelor undergoing emergent cardiothoracic surgery requiring CPB, using platelet reactivity to adenosine…
- Trial name
- CyTation (NCT04625764)
- Testing
- Blood sampling and analysis
- Where
- 4 sites in Germany, Luxembourg
- Volunteers
- 6 people
- Sponsor
- CytoSorbents Europe GmbH
Nitroprusside, Thyroid Hormones
Clinical Study Investigating the Effect of Sodium Nitroprusside Infusion on Thyroidal Function
Whether use of SNP during cardiac surgery has any effect on thyroid function has not yet been investigated in humans. The aim of this study was to investigate the effects of SNP administration during the rewarming period of…
- Trial name
- NCT00636584
- Testing
- sodium nitroprusside
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Kavaklıdere Umut Hospital
Coronary Artery Disease, Morphologic Change
IVUS Study for SV Graft: Y-composite vs Aortocoronary Conduit
Left internal thoracic artery (LITA) has been acknowledged as the first graft of choice for coronary artery bypass grafting (CABG).
- Trial name
- CONFIG (NCT04782492)
- Testing
- graft configuration in coronary artery bypass grafting
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Ho Young Hwang
Coronary Artery Bypass Grafting
Effects of CUrcuminoids on Coronary Artery byPass graftIng-related myocarDial Infarction Study
It is well-established that myocardial infarction (MI) associated with coronary artery bypass graft surgery (CABG) predicts the poor outcome.
- Trial name
- CUPID (NCT01528514)
- Testing
- Curcuminoids
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Wanwarang Wongcharoen, MD.
Complication of Coronary Artery Bypass Graft, Atrial Fibrillation
Atrial Fibrillation Prevention in Post Coronary Artery Bypass Graft Surgery With Cryoablation for Ganglionic Plexi
Atrial fibrillation after coronary artery bypass graft is a common complication. The investigators have thought that the mechanism of temporarily postoperative atrial fibrillation is closely related to the autonomic nervous…
- Trial name
- NCT02035163
- Testing
- Two sites cryoablation
- Where
- South Korea
- Sponsor
- Yong Seog Oh
Coronary Artery Bypass Graft Surgery(CABG)
Effects of Balance Training on Functional Capacity of Patients After Coronary Artery Bypass Grafting Surgery
Background:There are still many gaps in research concerning the effect of balance training on functional capacity of patient after coronary artery bypass graft.
- Trial name
- NCT06490458
- Testing
- Balance Training
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Coronary Artery Bypass, Thrombosis
Evaluating the Role of Thrombin in Saphenous Vein Graft Failure After Heart Bypass Surgery
Heart bypass surgery, also known as coronary artery bypass graft (CABG) surgery, creates a detour around the blocked part of a heart artery to restore blood supply to the heart muscle.
- Trial name
- NCT00481806
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- University of Arizona
Adult Patients Undergoing CABG
Effect of Preoperative Stellate Ganglion Block on Postoperative Atrial Fibrillation After Coronary Artery Bypass Grafting
The primary objective of this study is to determine the feasibility of preoperative stellate ganglion block in reducing the incidence of postoperative atrial fibrillation in patients undergoing CABG.
- Trial name
- NCT07271615
- Testing
- Stellate Ganglion Block
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital
Saphenectomy, No Touch
Morbidity of Conventional and No-touch Saphenectomy in Coronary Artery Bypass Grafting.
A clinical research project will be carried out that will consist of a non-inferiority study. The objective is to compare the morbidity of two different surgical techniques for the extraction of the internal saphenous vein…
- Conditions
- Saphenectomy, No Touch, Coronary Artery Disease, Cardiovascular Diseases
- Trial name
- TNT (NCT06496321)
- Testing
- Conventional Saphenous vein harvest, No touch Saphenous vein harvest
- Where
- Uruguay
- Volunteers
- 52 people
- Sponsor
- Instituto Nacional de Cirugia Cardiaca, Uruguay
Coronary Artery Bypass Surgery, Coronary Heart Disease
Clinical Study to Evaluate Nesiritide in Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery A014 / NAPA
The purpose of this study is to assess the effects of nesiritide compared to placebo when given with standard of care therapies, on kidney function, heart function and the need of other treatments in heart failure patients…
- Conditions
- Coronary Artery Bypass Surgery, Coronary Heart Disease, Coronary Artery Bypass Grafting, Cardiopulmonary Bypass
- Trial name
- NCT00653042
- Testing
- Nesiritide
- Volunteers
- 305 people
- Sponsor
- Scios, Inc.
Coronary Artery Disease
Endothelial Progenitor Cells
Vascular stenosis as a result of neointimal hyperplasia is a major clinical problem that has an impact on multiple and diverse disciplines, including cardiology (coronary restenosis), cardiothoracic and vascular surgery…
- Trial name
- NCT01686269
- Testing
- blood collecting
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Far Eastern Memorial Hospital
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