Clinical trials: Coronary Artery Bypass
Embolic Stroke, Postoperative Cognitive Dysfunction
Perfusion Pressure Cerebral Infarction Trial (PPCI)
STUDY HYPOTHESIS In cardiac surgery the volume of perioperative cerebral infarctions can be reduced by increasing mean arterial pressure (MAP) during the cardiopulmonary bypass procedure.
- Trial name
- PPCI (NCT02185885)
- Testing
- Increased bloodpressure during CPB.
- Where
- Denmark
- Volunteers
- 197 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Myocardial Revascularization, Atherosclerosis
Coronary Artery Bypass Grafting: Factors Related to Late Events and Saphenous Graft Patency
The purpose of this study is to determine the relations between conventional and unconventional risk factors and adverse clinical events at follow-up (including coronary bypass patency) in patients undergoing surgical myocardial…
- Trial name
- NCT00755248
- Testing
- Coronary Artery Bypass Grafting
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Centro Cardiologico Monzino
Coronary Artery Disease, Post Operative Pain
Ketorolac-an Option for Post Operative Pain Management After Elective Cardiac Surgery.
OBJECTIVE: The purpose of this study was to compare the efficacy of Ketorolac versus Paracetamol as an adjunct to Nalbuphine in the management of post-operative pain following elective cardiac surgery.
- Conditions
- Coronary Artery Disease, Post Operative Pain, Analgesia, Coronary Artery Bypass Grafting Surgery
- Trial name
- KOPAC (NCT05361824)
- Testing
- Ketorolac Injection, Paracetamol
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- National Institute of Cardiovascular Diseases, Pakistan
Right Ventricular Function, Prone Position
Bedside Assessment of Right Ventricular Output Lying in Prone Or Supine
Right ventricular failure (RVF) is a common complication to cardiac surgery, which is associated to mortality, kidney failure, stroke, prolonged mechanical ventilation and ICU stay.
- Conditions
- Right Ventricular Function, Prone Position, Atelectasis, Atelectases, Postoperative Pulmonary
- Trial name
- BAROLO (NCT07632027)
- Testing
- Prone position
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Sahlgrenska University Hospital
Ischemic Heart Disease
The Danish On-pump, Off-pump Randomization Study (DOORS)
Background: Coronary artery bypass grafting (CABG) can be performed either with or without the use of cardiopulmonary bypass (CPB) to obtain myocardial re-vascularisation.
- Trial name
- NCT00123981
- Testing
- Off-Pump Coronary Artery Bypass Grafting
- Where
- Denmark
- Volunteers
- 900 people
- Sponsor
- Kim Houlind
Ischemic Heart Disease, Atherosclerosis
Graft Patency as a Predictor of Health-related Quality of Life.
The health-related quality of life questionnaire "EQ-5D" has been collected in connection with several interventional and observational studies where the no-touch vein harvesting technique in CABG has been used.
- Trial name
- NCT02547194
- Where
- Sweden
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Örebro County Council
C.Surgical Procedure; Cardiac
HELIox CardiOPlegia Trial During Cardiac surgERy
The HELICOPTER-1 Trial is a single centre pilot study to determine the feasibility of administering Heliox in cardioplegia during cardiac surgery and whether it has the potential to reduce the incidence and severity of myocardial…
- Trial name
- HELICOPTER-1 (NCT02745951)
- Testing
- Heliox, Standard of care
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Unity Health Toronto
Coronary Artery Disease
Impact of Three Body Positioning Strategies in the Drainage Fluids After Coronary Artery Bypass Surgery
To investigate different strategies of body positioning associated to early corporal mobilization and verify the impact int the time and quantification of thoracic and mediastinal drainage, pulmonary complications and time of…
- Trial name
- positioning (NCT02525289)
- Testing
- Bed Rotation Group, Orthostatic Group
- Volunteers
- 101 people
- Sponsor
- University of Sao Paulo General Hospital
Cardiac Surgery Patient, Postoperative Pain
Effect of Intraoperative Morphine on Postoperative Pain After CABG
Ethics committee approval was obtained for this study, which was planned as a prospective, randomized, controlled, single-center trial to be conducted in patients undergoing coronary artery bypass grafting (CABG) surgery between…
- Conditions
- Cardiac Surgery Patient, Postoperative Pain, Pain After Surgery
- Trial name
- NCT07472959
- Testing
- In this study, morphine administration, which is routinely and frequently used in our operating room for patients undergoing CABG, was applied as an additional intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Coronary Artery Disease, Coronary Artery Bypass Graft Surgery
Transitional Rehabilitation in CABG Patients
The goal of this research study is to understand whether an at-home exercise program started soon after CABG surgery, and continuing for 4 weeks following discharge from the hospital, can preserve or improve physical function.
- Trial name
- NCT03892460
- Testing
- neuromuscular electrical stimulation
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Vermont
Angina Pectoris
Evaluation of Graft Material in Coronary Artery Bypass Grafting (CABG)
The aim of the study is to evaluate the patency in different kinds of vessels used as graft material in coronary artery bypass grafting.
- Trial name
- NCT01310725
- Testing
- Coronary artery bypass grafting
- Where
- Sweden
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Coronary Artery Disease, Cardiac Rehabilitation
Home-based Transitional Telerehabilitation in Cardiac Recovery
The main aim is to determine the impact of home video-based cardiac rehabilitation program on elderly patients' health-related quality of life and therapeutic self-care post-coronary revascularization
- Trial name
- NCT06192290
- Testing
- Home-based transitional Cardiac Telerehabilitation
- Where
- Egypt
- Volunteers
- 118 people
- Sponsor
- Mansoura University
Coronary Artery Disease, Coronary Artery Bypass Graft (CABG)
Photobiomodulation in Coronary Artery Bypass Grafting With No-Touch vs Conventional Saphenous Vein Harvesting.
This randomized, double-blind clinical trial aims to evaluate the impact of photobiomodulation therapy on postoperative outcomes in patients undergoing coronary artery bypass grafting (CABG).
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Graft (CABG), Surgical Wound Healing
- Trial name
- PHOTON (NCT07699679)
- Testing
- Photobiomodulation Therapy, Conventional Saphenous Vein Harvesting, No-Touch Saphenous Vein Harvesting
- Where
- Brazil
- Volunteers
- 292 people
- Sponsor
- Federal University of São Paulo
Coronary Artery Disease, Coronary Artery Bypass Graft Surgery
The Effect of Listening to Holy Quran Recital on the Incidence of Delirium Post-CABG
This study is planned to check the effect of holy Quran recital on the development of delirium after conronary artery bypass graft surgery (CABG).
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Graft Surgery, Delirium, Postoperative
- Trial name
- NCT06346990
- Testing
- Holy Quran Recital
- Volunteers
- 264 people
- Sponsor
- Applied Science Private University
Coronary Artery Bypass Grafting, Postoperative Acute Kidney Injury
Trajectory-Based Phenotyping After Coronary Artery Bypass Surgery
Coronary artery bypass grafting is a commonly performed heart surgery, but patients may have different risks for postoperative complications even when their preoperative risk scores are similar.
- Conditions
- Coronary Artery Bypass Grafting, Postoperative Acute Kidney Injury, Postoperative Complications, Risk Stratification
- Trial name
- NCT07598682
- Testing
- Early Postoperative Phenotype Classification
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Bursa Sevket Yilmaz Training and Research Hospital
Myocardial Ischemia, Coronary Artery Bypass Grafting
The Effects of Allicor on Patients After Coronary Arteria Revascularization Treatment
Coronary revascularization interventions such as coronary artery bypass graft (CABG) and percutaneous coronary intervention (PCI) are the standard of surgical treatment of patients with myocardial ischemia.
- Conditions
- Myocardial Ischemia, Coronary Artery Bypass Grafting, Coronary Arteriosclerosis, Percutaneous Coronary Revascularization
- Trial name
- TEA-CART (NCT05803759)
- Testing
- Allicor
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Institute for Atherosclerosis Research, Russia
Coronary Artery Bypass
Prasugrel for Prevention of Early Saphenous Vein Graft Thrombosis
This is a randomized-controlled clinical trial that will randomize 120 patients undergoing clinically-indicated coronary artery bypass graft surgery to prasugrel at a dose of 10 mg daily or matching placebo for 12 months…
- Trial name
- NCT01560780
- Testing
- Prasugrel
- Where
- 4 sites in United States
- Volunteers
- 84 people
- Sponsor
- VA Office of Research and Development
Counterpulsation, Coronary Artery Bypass
Efficacy of External CounterPulsation for Postoperative Coronary Artery Bypass Grafting Patients
The aim of this study is to evaluate the effect of External CounterPulsation on postoperative heart function and vein graft failure rates of coronary artery bypass grafting patients.
- Trial name
- SEECABG (NCT03235323)
- Testing
- External Counterpulsation
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Mengya Liang
Coronary Artery Disease, Coronary Stenosis
Transit Time Flow Measurement in Coronary Surgery
Transit-time flowmetry (TTFM) allows grafts quality control during coronary artery bypass surgery by measuring the flow volume through them.
- Conditions
- Coronary Artery Disease, Coronary Stenosis, Coronary Bypass Graft Stenosis
- Trial name
- COLLATERAL (NCT06471062)
- Where
- Italy
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Coronary Artery Bypass Grafting (CABG) Surgery
Improving Adherence to Medication After Coronary Artery Bypass Surgery (CABG) in Older Adults
Coronary artery bypass grafting (CABG) surgery is often performed in elderly patients, but non-adherence to post-CABG guideline medications is a common and serious clinical concern in this age group.
- Trial name
- NCT02109523
- Testing
- Motivational Interviewing (MI, volitional intervention, Routine discharge counseling
- Where
- 13 sites in Iran
- Volunteers
- 288 people
- Sponsor
- Qazvin University Of Medical Sciences
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