Clinical trials: Coronary Artery Bypass Graft
Coronary Artery Disease
A Study of Hemopure® to Enhance Tissue Preservation During Cardiopulmonary Bypass Surgery
The purpose of this study is to determine if Hemopure® will enhance tissue preservation during Cardiopulmonary Bypass surgery.
- Trial name
- NCT00301535
- Testing
- HBOC-201 (hemoglobin glutamer-250 bovine)
- Where
- 3 sites in Greece, South Africa and 1 more
- Volunteers
- 60 people
- Sponsor
- Biopure Corporation
Atrial Fibrillation
READ-POAF Pilot Studies Postoperative Atrial Fibrillation After Cardiac Surgery
Postoperative atrial fibrillation after coronary artery bypass grafting will be monitored up to 1 year after the procedure by implanting a Reveal XT internal loop recorder two weeks before the surgery.
- Trial name
- NCT01530750
- Where
- 2 sites in Netherlands
- Volunteers
- 40 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Bloodloss
This Study Will Compare the Effect of Starch Containing to Non-Starch Containing Intravenous Fluid on Blood Loss During Coronary Artery Bypass Graft Surgery
The overall aim of this study is to determine if there is a bleeding risk associated with the use of starch-containing fluids during cardiac surgery.
- Trial name
- NCT00801190
- Testing
- HES (130/0.4), Ringer's Lactate
- Volunteers
- 500 people
- Sponsor
- St. Boniface Hospital
Coronary Artery Bypass Graft Redo, Heart Valve Diseases
SONOlysis in Risk REduction of Symptomatic and Silent Brain infarCtions dUring Cardiac surgEry
The aim of the project is to demonstrate a fibrinolytic effect of sonothrombolysis (continual transcranial Doppler monitoring) using 2 MHz diagnostic probe on the reduction of risk of brain infarctions due to the activation of…
- Trial name
- SONORESCUE (NCT01591018)
- Testing
- sonolysis, cardiac surgery
- Where
- Czechia
- Volunteers
- 120 people
- Sponsor
- University Hospital Ostrava
Post Coronary Artery Bypass Grafting
Effectiveness of Incentive Spirometer and Diaphragmatic Breathing Exercise on ABG Measures in Post-CABG Patients
The rate of pulmonary complications following Coronary artery bypass graft (CABG) is high. Early pulmonary exercises are important in preventing this complication following cardiac surgery.
- Trial name
- NCT05684679
- Testing
- Incentive spirometer plus Chest physiotherapy, Diaphragmatic breathing exercise plus Chest physiotherapy
- Where
- Saudi Arabia
- Volunteers
- 30 people
- Sponsor
- King Saud University
Surgery, Coronary Artery Disease
Role of Sugammadex as Reversal Agent in Patients Extubated Immediately After Isolated Coronary Artery Bypass Grafting Surgery
The purpose of this study is to examine whether the use of Sugammadex will reduce time from reversal to extubation and improve other post extubation outcomes in Coronary artery bypass grafting patients.
- Trial name
- NCT03939923
- Testing
- Rocuronium, Neostigmine, Glycopyrrolate
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- West Virginia University
Coronary Artery Occlusive Disease
The Effect of Tranexamic Acid on Postoperative Blood Loss and Coagulation in Patients With Preoperative Anemia Undergoing Off-Pump Coronary Artery Bypass Graft; Double Blind Randomized Control Study
The Effect of Tranexamic Acid on Postoperative Blood loss and Coagulation in Patients with Preoperative Anemia Undergoing Off-Pump Coronary Artery Bypass Graft; double blind randomized control study.
- Trial name
- NCT01067638
- Testing
- Tranexamic Acid
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Yonsei University
Coronary Artery Bypass
Systematic Assessment of Competitive Flow in Coronary Artery Bypass Grafts by Wave Intensity Analysis
Narrowing of the arteries that supply blood to the heart can lead to heart attacks and death. One way of treating this is to use artery and vein grafts from other parts of the body to bypass the narrowing.
- Trial name
- NCT01118468
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Imperial College London
Coronary Bypass Graft Stenosis, Valvular Heart Disease
Comparison of Post-operation Cardiopulmonary Capacity of Patients Underwent Conventional and Robot-assisted Coronary Artery Bypass Graft and Valve Replacement Surgery
Robotic surgery is one of the most popular minimally invasive procedures for patients with coronary artery disease or valvular diseases.
- Trial name
- NCT05430568
- Testing
- robot-assisted surgery
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taichung Veterans General Hospital
Coronary Artery Disease, Chronic Kidney Disease
Effects of Surgical, Percutaneous or Medical Treatments for Coronary Artery Disease on Renal Function: Long-Term Outcome. Cardiorenal-trial.
Background: Coronary artery disease (CAD) is treated with coronary artery bypass grafting (CABG), percutaneous coronary intervention (PCI), or optimized medical therapy (OMT).
- Trial name
- NCT07195747
- Testing
- Creatinine
- Where
- Brazil
- Volunteers
- 1,700 people
- Sponsor
- Instituto do Coracao
Coronary Artery Bypass Grafting, Postoperative Acute Kidney Injury
Trajectory-Based Phenotyping After Coronary Artery Bypass Surgery
Coronary artery bypass grafting is a commonly performed heart surgery, but patients may have different risks for postoperative complications even when their preoperative risk scores are similar.
- Conditions
- Coronary Artery Bypass Grafting, Postoperative Acute Kidney Injury, Postoperative Complications, Risk Stratification
- Trial name
- NCT07598682
- Testing
- Early Postoperative Phenotype Classification
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Bursa Sevket Yilmaz Training and Research Hospital
Postoperative Complications
Cardiopulmonary Exercise Testing in Cardiosurgery Patients
Cardiopulmonary exercise testing (CPET) is considered to be a gold standard in pre-operative risk assessment and stratification of high risk patients scheduled for major surgery.
- Trial name
- NCT06702059
- Testing
- Cardiopulmonary exercise testing
- Where
- 2 sites in Czechia
- Volunteers
- 130 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Coronary Artery Bypass, Off-Pump
Cell Savers and Blood Quality
Cell savers are routinely used in our hospital during off-pump coronary artery bypass grafting to retrieve and wash blood that is lost during the operation.
- Trial name
- NCT02046824
- Testing
- Xtra®, Sorin cellsaver, C.A.T.S.®, Fresenius cellsaver, CardioPAT®, Haemonetics, cellsaver
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- University Medical Center Groningen
Coronary Artery Disease, Postoperative Pulmonary Complications
Flow-Controlled vs. Pressure-Controlled Ventilation in CABG: Effects on Lung Aeration and Diaphragm Function
Pulmonary atelectasis and loss of lung aeration are common complications following cardiac surgery with cardiopulmonary bypass (CPB) and are associated with impaired oxygenation and prolonged mechanical ventilation.
- Conditions
- Coronary Artery Disease, Postoperative Pulmonary Complications, Pulmonary Atelectasis, Postoperative, Diaphragm Dysfunction
- Trial name
- FCV-PCV-DTI-LU (NCT07800741)
- Testing
- Flow-Controlled Ventilation, Pressure-Controlled Ventilation (PCV)
- Where
- Turkey (Türkiye)
- Volunteers
- 154 people
- Sponsor
- Koşuyolu Kartal Heart Training and Research Hospital
Chronic Total Occlusion
CABG Versus PCI in Patients With Isolated LAD Chronic Total Occlusion
The aim of this study is to compare coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) in the treatment of isolated chronic total occlusion (CTO) of the left anterior descending (LAD) artery in…
- Trial name
- RITUAL (NCT07373678)
- Testing
- Coronary Artery Bypass Grafting, Percutaneous Coronary Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 302 people
- Sponsor
- Mersin Medicalpark Hastanesi
Coronary Artery Bypass
One-lung Ventilation During Internal Thoracic Artery Grafting in Cardiac Surgery
Coronary artery bypass grafting is a current cardiac surgery. Internal thoracic artery is usually taking to restore coronary revascularization, and its dissection can lead to accidental or voluntary pleural effusions.
- Trial name
- VUPPAM (NCT02823054)
- Testing
- EZ-Blocker
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Coronary Artery Disease, Aspirin Resistance
Dual Antiplatelet Therapy in Patients With Aspirin Resistance Following Coronary Artery Bypass Grafting
Reactive platelet hyperactivity following coronary artery bypass grafting (CABG) might lead to thrombotic complications and major ischemic cardiac events.
- Trial name
- NCT01159639
- Testing
- Clopidogrel
- Where
- Croatia
- Volunteers
- 200 people
- Sponsor
- University of Zagreb
Anxiety, Discharge Readiness
The Effect of Nurse-led Video-assisted Discharge Training on Anxiety and Readiness for Discharge After Coronary Artery Bypass Graft Surgery
This clinical trial aims to evaluate the effect of nurse-led video-assisted discharge education on discharge readiness and anxiety in patients undergoing coronary artery bypass graft surgery.
- Conditions
- Anxiety, Discharge Readiness, Nursing, Training
- Trial name
- NCT06806631
- Testing
- Video assisted discharge training
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people
- Sponsor
- Uskudar University
Coronary Artery Disease
SYNTAX Study: TAXUS Drug-Eluting Stent Versus Coronary Artery Bypass Surgery for the Treatment of Narrowed Arteries
The SYNTAX trial is designed to determine the best treatment for patients with complex coronary disease (blocked or narrowed arteries in both the right and left sides of the heart) by randomizing patients to receive either…
- Trial name
- SYNTAX (NCT00114972)
- Testing
- Polymer-based Paclitaxel-Eluting TAXUS Express2-SR Stent, Coronary Artery Bypass Surgery
- Where
- 106 sites in United States, Austria and 16 more
- Volunteers
- 1,800 people
- Sponsor
- Boston Scientific Corporation
Wounds, Infection
Autologous Platelet Gel in Wound Healing of Coronary Artery Bypass Grafting (CABG) Patients
This study will determine if autologous platelet gel (APG) on sternal incision and conduit sites will improve wound healing and decrease infection in coronary artery bypass grafting surgery patients.
- Trial name
- NCT00672672
- Testing
- autologous platelet gel
- Sponsor
- University of Nebraska
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